JP2008156467A - Positive feeling improver for male - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a positive feeling improver for a male contributing to formation of sufficient human relation in an environment that men and women in the office work together and satisfying a fundamental wish of the male. <P>SOLUTION: A compound incorporated with at least one kind of perfume ingredient of citrus-based, herb-based, green-based and musk-based, and 4,16-androstadien-3-one is used as the positive feeling improver for the male. As the perfume ingredient also used with the 4,16-androstadien-3-one, citral, limonene, mint, linalool, linalyl acetate, pinene, cineole, citronellol, hexenal, muscone, civetone, exaltolide and ambrettolide are preferable, particularly limonene, linalool and linalyl acetate are preferable. <P>COPYRIGHT: (C)2008,JPO&INPIT

Description

  The present invention relates to an agent for improving male preference for causing a woman to have a favorable impression on a man.

  In recent years, the advancement of women into society has become natural and the proportion of women in various workplaces has increased. While engaging in the same work in various workplaces, women and men have different sensitivities, which may cause unnecessary friction. Of course, in social life, especially in the workplace, it is better to have a good impression of each other than to hate each other. It is well known that good human relations are important for the efficiency of work that requires coordination in the workplace.When women and men with different sensitivities work together, their negative impressions are It is necessary to avoid it.

  In order to improve each other's impression, it is necessary to be careful about cleanliness, be careful about clothes, etc., but such normal methods prevent the drunkenness of human relationships due to stress in modern life, especially at work It is not possible. For women, perfume is often used to change the impression of men to women in a favorable direction. However, since there are a wide range of preferences for perfumes, in some cases, a negative impression may be given. .

  Conventionally, there has been proposed a female recognition enhancer that changes the impression of men towards women in a favorable direction, although it is not intended to prevent the above-described unnecessary habits of human relationships due to stress in modern life, particularly in the workplace (Patent Literature). 1). This female recognition enhancer is composed of a steroid having 19 carbon atoms, and specifically, the steroid having 19 carbon atoms is androsterone, androstenone, and dehydroandrosterone. And the effect is said to be that the woman is strongly recognized and a favorable impression is formed on the man.

Japanese Patent Laid-Open No. 08-003580

  The agent disclosed in Patent Document 1 makes men strongly recognize women, does not have a bidirectional action, and does not have an effect of changing the impression of men around women to favorable ones. It is clear that it is not enough to change the impression of men around women to a favorable one in order to form good human relationships between men and women with different sensibilities in the environment where men and women work together at the current workplace etc. It is necessary that the impression is good in both directions. In this sense, there is a demand for an agent for improving male preference that enables a woman to easily have a good impression on surrounding men.

In addition, although the goal is to improve the human relationship when men and women in the workplace work together, the desire for men to have a positive impression on women This is the basic desire of men regardless of east or west. For this reason, men train their bodies and take care of cleanliness. Many of these are visually appealing to women, but visually changing impressions often requires time and effort and is limited. On the other hand, olfactory information is also important as an influence on the impression formation between men and women in a situation where men and women face each other. And changing an olfactory impression is much simpler than changing a visual impression. As a method for controlling such olfactory information and improving the impression on women, a method for reducing discomfort due to body odor such as an antiperspirant, or a preferable scent such as a perfume is used. The method of giving is mentioned. However, the action of antiperspirants is to suppress perspiration, and to suppress the generation of unpleasant odors when sweating, so that it does not seem unpleasant, so that it can be seen more favorably Not for. Moreover, the improvement effect of the impression in the situation where you are not sweating cannot be expected. As for the method for imparting a preferable scent such as perfume, as described above, the scent of the scent varies widely, and in some cases, it may have an adverse effect. Even if the taste as a scent is evaluated, the preference for a man with the scent cannot be changed greatly.
In response to the basic desire of men to have a good impression on such men's women, the provision of an agent for improving men's preference that can realize this is greatly welcomed.

  The present invention has been made in view of the above-described conventional circumstances, and the problem can contribute to the formation of good human relations in an environment where men and women in the workplace work together, and the basics of men The object is to provide an agent for improving likability to men that can satisfy the desires.

In order to solve the above-mentioned problems, the present inventors have conducted intensive studies, experiments, and studies, and have obtained the following knowledge.
In other words, in an environment where men and women are mixed, when 4,16-androstadien-3-one is released in the atmosphere to a predetermined concentration range and is naturally sucked by a woman, the impression of surrounding men is preferable. When a specific perfume ingredient is released simultaneously with the release of 4,16-androstadien-3-one, the effect of improving the preference for males of 4,16-androstadien-3-one is further enhanced. It was discovered.

  As the specific perfume component, citrus, herb, green, floral, resin, and musk are preferable, and it has also been confirmed that at least one selected from these groups may be used. Citrual fragrance ingredients that have been confirmed to be effective are citral and limonene, herbal fragrance ingredients are mint, green fragrance ingredients are hexenal, and floral fragrance ingredients are linalool, linalyl acetate, and citronellol. Yes, the resin-based fragrance components were pinene and cineole, and the musk-based fragrance components were Muscon, Cibeton, Exaltride, and Amblet Ride.

  In addition, the citrus-type fragrance | flavor component said here is a fragrance | flavor component classified by the definition that it has the fragrance which recalls citrus fruits, and citral and limonene are mention | raise | lifted as a typical thing. The herb-based fragrance component is a fragrance component classified by the definition of having an aroma reminiscent of an edible herb, and representative examples include mint and sage. Moreover, a green fragrance | flavor component is a fragrance | flavor component classified by the definition that it has the fragrance which recalls green leaves, and a green leaf alcohol and green leaf aldehyde are mentioned as a typical thing. A floral fragrance | flavor component is a fragrance | flavor component classified by the definition that it has the fragrance which recalls a flower, and citronellol and geraniol are mentioned as a typical thing. The resin-based fragrance component is a fragrance component classified based on the definition of having an aroma reminiscent of a tree resin, and representative examples include pinene and cineole. And a musk type fragrance | flavor component is a fragrance | flavor component classified by the definition that it has the fragrance which recalls the secretion of an animal, and includes Muscon and Sibeton as an intentional thing.

  The present invention has been made on the basis of the aforementioned findings. That is, the male sensibility improver according to the present invention comprises at least one fragrance ingredient of citrus, herb, green, floral, resin, and musk, and 4,16-androstadiene-3- It is characterized by containing ON.

  As the citrus fragrance component, citral and limonene are preferable. As the herb fragrance component, mint is preferable. As the green fragrance component, hexenal is preferable. As the floral fragrance component, linalool and linalyl acetate are preferable. Citronellol is preferable, and the resin-based fragrance component is preferably pinene or cineole, and the musk-based fragrance component is preferably muscone, cibetone, exaltride, or ambretride.

  The agent for improving men's preference for men according to the present invention can change a woman's impression of surrounding men to a favorable one, and contributes to the formation of good human relations in an environment where men and women in the workplace work together There is an effect that can be done.

As described above, the agent for improving male sensitivity according to the present invention includes at least one fragrance component of citrus, herb, green, floral, resin, and musk, and 4,16-androstadiene. It is characterized by containing -3-one.
Hereinafter, 4,16-androstadien-3-one, which is an active ingredient of the male sensibility improver according to the present invention, and specific various perfume ingredients will be described individually.

  4,16-androstadien-3-one is a compound belonging to 16-androstene steroid which is a compound having a pheromone-like action. This compound has an effect of changing the impression of a woman to a man by making the woman suck a concentration in a predetermined range.

  When the 4,16-androstadien-3-one is blended as an active ingredient in the male sensibility improver of the present invention, the blending amount is 0.01-100 ppm (0.01 μg / mL-100 μg / mL). ) Is preferable, and more preferably 0.1 to 10 ppm (0.1 μg / mL to 10 μg / mL). If the blending amount is less than 0.01 ppm, it is not possible to obtain the desired effect of improving male preference. Moreover, when it exceeds 100 ppm, it may feel uncomfortable depending on the woman who inhaled.

  Examples of the fragrance ingredients that increase the effect of improving the sensibility to males that occur in women when used in combination with the amount of 4,16-androstadien-3-one include the following plant-based fragrance ingredients and animal-based fragrance ingredients: Can do. As the plant-based fragrance component, citrus-based, herbal-based, green-based, floral-based, and resin-based fragrance components are preferable. Specifically, these plant-based fragrance components are preferably citral, limonene, mint, linalool, linalyl acetate, pinene, cineol, citronellol, and hexenal. Further, as the animal-based fragrance component, a musk-based fragrance component is preferable, and more specifically, muscone, cybeton, exaltride, and amblet ride are preferable. In environments such as workplaces where work is important, combinations with plant-based fragrance ingredients that can also be expected to have a relaxing effect and soothing effect are preferred, and in associations between men and women outside the workplace, combinations with animal-based fragrance ingredients are more suitable for men. It can be said that it is preferable because it strengthens the discrimination against. Among these plant-based fragrance components and animal-based fragrance components, limonene, linalool, and linalyl acetate are preferable from the viewpoint of an auxiliary effect that increases the effect of improving the sensitivity to men.

  The blending amount of the specific fragrance component is desirably set within a range of 0.001 to 10% on a weight basis. If the blending amount is less than 0.001%, it is not perceived by human olfaction and the desired effect on improving male likability cannot be obtained. If it exceeds 10%, some users may feel uncomfortable. In addition, as a compounding amount as a fragrance | flavor, 0.001% is a very low value as a compounding amount for being recognized by an odor sense, but it can be recognized by an odor sense by such a low compounding amount. , 16-androstadien-3-one. It is presumed that this action on olfaction also has a positive effect on the effect of improving the preference for males, which is the main purpose of the present invention.

  Both the plant-based fragrance component and the animal-based fragrance component are known fragrance components, and can be obtained from a specific part of a specific plant or an animal secretion by a conventionally known method. It is also well known that it can be partially obtained by chemical synthesis, and these synthetic products may be used. Moreover, you may use the essential oil containing these fragrance | flavor components.

  In the male sensibility improver according to the present invention, a suitable blending ratio of the 4,16-androstadien-3-one and a specific perfume component is 1:10 as a blending ratio in the final preparation. ˜1: 100,000 is preferable, and more preferably 1: 100 to 1: 10000. When the blending ratio of 4,16-androstadien-3-one increases beyond the blending ratio, the odor of 4,16-androstadien-3-one becomes too strong and the good effect of the present invention is obtained. It may not be possible. In addition, when the blending ratio of 4,16-androstadien-3-one falls below the blending ratio, the olfactory stimulation of 4,16-androstadien-3-one may be insufficient, and the present invention. In some cases, it is not possible to obtain a good effect.

  The agent for improving male sensitivity according to the present invention can be applied to a wide variety of specific preparations. For example, the agent for improving the preference for men according to the present invention is an environmental fragrance composition such as perfume, cosmetics, body cleaning agent, body care agent such as bathing agent, air freshener, space fragrance, clothing care agent, clothing cleaning agent, etc. In addition, it can be used for body clothing materials and accessory materials such as fabric products, leather products, chemical fiber products, and plastic products. Depending on the final product, known ingredients can be added. Examples of the additive component include surfactants, oils, alcohols, moisturizers, thickeners, preservatives, chelating agents, pH adjusters, fragrances, dyes, ultraviolet absorption / scattering agents, vitamins, and water. These can be appropriately blended as necessary.

  Examples of the present invention will be described below. The following examples are only suitable examples for explaining the present invention, and do not limit the present invention.

(Examples 1-12, Comparative Examples 1-20)
Twelve evaluation samples (Examples 1 to 12) and 20 comparative samples (Comparative Examples 1 to 20) were prepared for the evaluation examples of male likability improvers in Examples, and each trial was performed using each evaluation sample as a fragrance. Taking the time to avoid being affected by the effects, 60 female panelists sucked in through the atmosphere, and after sucking, they looked at the face photo and evaluated the impression.

(Impression evaluation method)
For the impression evaluation, we used a male face-to-face photo, and a female panelist answered the impression of the face photo. As impressions, I asked about manly feelings and favorability, and asked them to answer the impression level of each item using VAS (visual analog scale). VAS presents a 10.0 cm long horizontal straight line, with the left end being the most negative (negative impression) and the right end being the most positive (positive impression). It is a method used for psychological evaluation by having a straight line mark whether it is located at a certain level. The measurement of the evaluation result was performed by measuring the position of the point marked by each panel as the distance from the left end and digitizing it. The most negative end (left end) was 0 point, and the most positive end (right end) was 10.0 point.

(Preliminary evaluation: Panel grouping and extraction of factors highly correlated with impressions)
Image data sold for research purposes by Softpia Foundation was used for the face photo. Among these, front face photographs of men in their 20s to 30s were arbitrarily selected and used. Female evaluators selected healthy women who had no problems with their olfaction in their 20s and 40s. As a preliminary evaluation, the conference room without characteristic odor was performed at room temperature. First, under the situation where no scent (evaluation sample) was presented, impression evaluation was performed on three face photographs arbitrarily selected from image data. As a result of having all the 60 panelists evaluate the three face photographs, the 60 panelists were divided into 12 groups consisting of 5 members per group so that the first impression evaluation points were equal.

(Evaluation of effects on facial impression by presenting evaluation samples)
Impression evaluation was performed on two points of “masculine impression” and “favorability” under the condition that the panel was sucked the evaluation sample. The evaluation was performed at room temperature using the same conference room where the preliminary evaluation was performed. Each of the 12 groups divided in the preliminary evaluation is sequentially sucked with different scent evaluation samples, and the face photograph is selected from 10 images in their 20s to 30s, excluding 3 images used in the preliminary evaluation. And all 12 groups evaluated the same 10 photos. The action method of the evaluation sample is to put about 15 mL of the evaluation sample solution prepared for each evaluation group in a 90 mm glass petri dish, and cover the petri dish at a position 60 cm from the end on the panel side of the desk on which the panel performs the evaluation. A simple fan-type aroma aroma (product name "Aroma Breeze NOVA", manufactured by Alta Corporation) is installed just behind it (on the opposite side of the panel), and the fan runs in the direction of the panel's face. The evaluation sample that volatilizes from the petri dish reaches the panel as a fragrance and is naturally sucked.

  The evaluation samples naturally sucked in each group are Examples 1 to 12 and Comparative Examples 1 to 20, and their compositions are shown in (Table 1) to (Table 5). In addition, the evaluation score for the evaluation sample of each example is shown by the average value of impression evaluation VAS value data of five female panelists (all evaluators in each group) for 10 face photographs.

  The following were used for each composition used for each evaluation sample shown in (Table 1) to (Table 5).

4,16-androstadien-3-one (abbreviated as AND in the table), 1,3,5 (10), 16-estraditetraen-3-ol (abbreviated as EST in the table), 5α-androst- As 16-en-3-one (abbreviated as ASN in the table), a product made by Stellaloids was used.
Further, as the solvent propylene glycol, one manufactured by Wako Pure Chemical Industries, Ltd. was used.

On the other hand, each fragrance | flavor component used the following commercial items, respectively.
Citral, limonene, hexenal, linalool, linalyl acetate, citronellol, pinene and cineole were those manufactured by Wako Pure Chemical Industries. Mint, Muscon, Sibeton, Exhaltride, and Amblet Ride were manufactured by We Mann Fis Fragrance.

  As is apparent from the above (Table 1) to (Table 5), 4,16-androstadien-3-one enhances the masculine impression, and furthermore, a specific fragrance component, particularly a citrus fragrance component such as citral, is used in combination. As a result, it was confirmed that, compared with the case where 4,16-androstadien-3-one was used alone, the favorable sensitivity of males was synergistically increased.

(Evaluation Examples 1 to 16, Evaluation Comparative Examples 1 to 18)
(Evaluation of fragrance by blending 4,16-androstadien-3-one)
As shown in (Table 6) to (Table 9), the amount of 4,16-androstadien-3-one in a 20 ppm monolauric acid polyoxyethylene sorbite (Nikko Chemical, trade name “GL-1”) solution And each fragrance | flavor component was melt | dissolved and the sample of each evaluation example 1-16 and evaluation comparative examples 1-18 was obtained. The following were used for each composition used for the samples of these evaluation examples 1 to 16 and evaluation comparative examples 1 to 18.

  As 4,16-androstadien-3-one (abbreviated as AND in the table), a product manufactured by Stellaloids was used. Further, as the solvent, polyoxyethylene sorbite monolaurate, a product manufactured by Nikko Chemicals was used.

On the other hand, each fragrance | flavor component used the following commercial items, respectively.
Citral, limonene, hexenal, linalool, linalyl acetate, citronellol, pinene and cineole were those manufactured by Wako Pure Chemical Industries. Mint, Muscon, Sibeton, Exhaltride, and Amblet Ride were manufactured by We Mann Fis Fragrance.

  10 mL of each sample was placed in a screw bottle with a diameter of 27 mm (manufactured by Maruemu, product number “NO.5”), the cap was closed, and the sample was left at room temperature. Then, it was evaluated whether or not the sample smelled when the cap was opened by a panel of specialists of 2 men and 3 women. The results are also shown in (Table 6) to (Table 9).

  As is clear from the above (Table 6) to (Table 9), when 4,16-androstadien-3-one and a fragrance component are combined, the concentration at which fragrance can be felt compared to the case where they are used alone. Was found to be low and the aroma enhanced. It was speculated that this aroma enhancing action by 4,16-androstadien-3-one is closely related to the action effect of the agent for improving male sensibility according to the present invention.

  As described above, the agent for improving men's preference for men according to the present invention can change a woman's impression of surrounding men to a favorable one, and is a good human being in an environment where men and women in the workplace work together. Can contribute to the formation of relationships.

Claims (4)

  Improves male preference, comprising at least one fragrance component of citrus, herb, green, floral, resin and musk and 4,16-androstadien-3-one Agent.   Citrus fragrance component is citral, limonene; herb fragrance component is mint; green fragrance component is hexenal; floral fragrance component is linalool, linalyl acetate, citronellol; resin fragrance component is pinene, cineol; musk fragrance component The agent for improving susceptibility to males according to claim 1, wherein the agent is Muscon, Siveton, Exaltride, or Amblet Ride.   3. The agent for improving susceptibility to men according to claim 1, wherein the amount of 4,16-androstadien-3-one is 0.01 to 100 ppm.   The compounding amount of the said fragrance | flavor component is 0.001 to 10 weight%, The male sensibility improvement agent of any one of Claims 1-3 characterized by the above-mentioned.