JP2008073163A - Medical sticking material and its manufacturing method - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a medical sticking material which is excellent in handleability and through which one relatively wide area part of the body surface to be stuck can be viewed, and to provide its manufacturing method. <P>SOLUTION: In the medical sticking material having an adhesive material layer on at least one surface of a base material, the base material 2 is a fibrous base material comprising a thermoplastic resin or a laminate base material of the fibrous base material 3 comprising the thermoplastic resin and a film base material 4, the fibrous base material 3 is provided with a part (heat fusion part) 20 fused by heat and a part (non heat fusion part) 10 not fused by heat at a part or whole of the periphery of the heat fusion part, and the sticking part of the heat fusion part is visualized. <P>COPYRIGHT: (C)2008,JPO&INPIT

Description

  The present invention relates to a medical patch having visibility and a manufacturing method thereof. More particularly, the present invention relates to a medical patch used for fixing a medical material to the skin, protecting or treating a skin or a wound in the medical field, and a manufacturing method thereof. The medical patch of the present invention can be used by sticking to the skin or other body surface for home use, sports use, cosmetic use, and the like.

  Sheet-like or roll-like patch materials are used for fixing medical materials such as tubes, gauze, and bandages used for treatment of diseases to the body surface, treating and protecting wounds and skin, and beauty.

  In general, a medical patch is required to have the property of following the movement of the skin (elongation and contraction of the skin), the property of adapting to unevenness, and the like. As a patch having these characteristics, a polyurethane film coated with a pressure sensitive adhesive is known. When this patch is used, the release paper placed on the pressure-sensitive adhesive is removed, a plastic film is placed on, for example, a wound surface, and the adhesive is fixed with the pressure-sensitive adhesive. Since this type of patch is extremely thin and flexible, and has no elasticity, it is very difficult to handle after removing the release paper, causing wrinkles on the film and adhesion between the films. .

  In order to improve this point, Patent Document 1 proposes a thin polymer film having a peelable frame attached to the outer periphery of the polymer film on the side opposite to the side to which the pressure-sensitive adhesive is applied. Has been. This patch has a frame to keep the film flat and free of wrinkles. Although it improves operability compared to conventional patches, it is the same when removing release paper and frames from the film. In addition, the film tends to wrinkle, and the frame is hard, so that it is difficult to apply the film particularly when applied to a curved portion of a human body. Furthermore, since the frame becomes unnecessary after being attached, the amount of garbage to be discarded increases.

  Accordingly, the present applicant has created a patch material in which a plastic film and a nonwoven fabric as disclosed in Patent Document 2 are laminated and an adhesive layer is provided on the entire surface of the plastic film opposite to the nonwoven fabric. This sticking material has very good operability, and even an extremely thin film can be stuck to the target part and stuck. However, since non-woven fabric is used as a base material, it lacks transparency, and there is another problem that it is impossible to apply it to the optimal position while looking at the wound site through the adhesive, or to observe the affected area after application. It was.

Therefore, the present applicant has further created a patch having good operability and improved transparency of the surface to be pasted (Patent Document 3). The patch of Patent Document 3 is obtained by laminating a non-woven fabric and a light transmissive and flexible plastic film, embossing at least the non-woven fabric, and providing a light transmissive adhesive layer on the entire surface of the plastic film opposite to the non-woven fabric. Is.
This patch material has good handleability when the area ratio of embossing is small, but the transparency decreases, and when the area ratio of embossing is large, the transparency increases but the handleability decreases. It was difficult to satisfy the properties at the same time.

  Moreover, in patent document 4, in the adhesive bandage which provided the adhesive layer in the base material which laminated the thermoplastic fiber cloth and the film, and the thermoplastic fiber cloth side surface of this base material, it was made to melt a thermoplastic fiber. A pattern-sealed one has been proposed. In order to prevent water from entering from around the bandage, this bandage only seals the pattern around the bandage and does not consider the visibility of the wound. It was not satisfactory.

Japanese Patent Publication No. 62-28994 Japanese Utility Model Publication No. 3-32345 Utility Model Registration No. 2535473 Japanese Patent Laid-Open No. 9-299396

  The present invention has been made in view of the above-described problems, and an object of the present invention is to handle easily and to see through a relatively large area portion of the body surface to be affixed. An object of the present invention is to provide a medical patch and a method for producing the same.

  As a result of conducting earnest research to achieve the above-mentioned problems, the present inventors have a fiber base material made of a thermoplastic resin or a laminated base material of a fiber base material made of a thermoplastic resin and a film base material as a base material. It has been found that a pressure-sensitive adhesive layer may be provided on at least one surface of the base material, and a predetermined portion of the base material may be melted by heat, and the present invention has been completed based on this finding.

  In order to solve the above-described problems, the present invention provides a medical patch having an adhesive layer on at least one surface of a substrate, wherein the substrate is a fiber substrate made of a thermoplastic resin or a fiber substrate made of a thermoplastic resin. It is a laminated base material of a material and a film base material, and the fiber base material is a part melted by heat (heat melted part) and a part that is not melted by heat in part or all of the periphery of the heat melted part. (Non-heat-melting part), The sticking site | part of the said heat-melting part can be visually recognized (Claim 1).

  As an embodiment of the invention of claim 1, the inventions of claims 2 to 8 below are preferable. That is, in the above-described first aspect, the non-thermal melted portion provided in the fiber base material has a frame shape around the base material (claim 2).

Furthermore, the thing of any one of the said Claim 1 or 2 WHEREIN: A heat fusion part shall be 16 to 85% of the area of the whole fiber base material (Claim 3). Moreover, the thing of any one of the said Claims 1-3 WHEREIN: The area of one heat-melting part shall be 1 cm < ² > or more (Claim 4). Furthermore, the thing of any one of the said Claims 1-4 WHEREIN: The bending resistance of the sticking material of a non-thermal-melting part shall be 10-40 mm / 20mm (Claim 5).

  Moreover, in the thing of any one of the said Claims 1-5, the visible light transmittance | permeability (wavelength 550nm) of a heat fusion part shall be 10% or more (Claim 6). Furthermore, in the thing of any one of the said Claims 1-6, it is set as the laminated base material in which a base material contains a nonwoven fabric or a nonwoven fabric (Claim 7). Moreover, the thing of any one of the said Claims 1-7 WHEREIN: An adhesive layer shall consist of a transparent or translucent adhesive (Claim 8).

  Further, as an invention of a manufacturing method, in a manufacturing method of a medical patch having an adhesive layer on at least one surface of a base material, a fiber base material made of a thermoplastic resin or a fiber base material made of a thermoplastic resin and a film A pressure-sensitive adhesive layer is provided on the base material laminated with the base material, and then a heat source is brought into contact with the base material side to form a part of the fiber base material that is melted by heat and melted by this heat. The formed part is formed so that the sticking part can be visually recognized.

According to the medical patch of the present invention, the entire base material is kept flat and free of wrinkles at the time of sticking by allowing a fiber material having flexibility, excellent followability, and a certain degree of elasticity to be present around the base material. In addition, the peripheral portion can be attached without wrinkles even in a bent portion.
In addition, when applying the patch, it can be applied while seeing through the affected part from the part melted by heat, so that it can be applied at an accurate position, and one part of the affected part is relatively wide even after application. It is possible to clearly observe the area of the area. Moreover, since the part melt | dissolved with the heat | fever is flexible and is excellent in followability | trackability, it does not produce discomfort during sticking.
Furthermore, according to the manufacturing method of the present invention, a relatively wide area portion can be visualized by a relatively simple method, and the manufacturing cost is reduced.

An embodiment of the present invention will be described below based on FIGS. In addition, the same code | symbol is used about the same site | part. HYPERLINK "javascript: fGetImage ('000003', 'FIG. 1', 'K2');" FIG. 1 shows a configuration diagram of an embodiment according to the adhesive material of the present invention, a) a front view, and b) a diagram. FIG. 5A is a cross-sectional view taken along line bb of FIG.
The patch 1 in the embodiment of FIG. 1 has a structure in which a pressure-sensitive adhesive layer 5 is provided on one surface of a substrate 2 and the surface of the pressure-sensitive adhesive layer 5 is covered with a peelable pressure-sensitive adhesive protective layer 6. Yes. The base material 2 is a laminated base material in which the nonwoven fabric 3 and the film 4 are laminated, and forms a portion (hereinafter also referred to as a heat melting portion) 20 in which the nonwoven fabric 3 is melted by heat. In this example, a part 20 melted by heat formed into a film in a circular shape at the substantially central part of the base material, and a part not melted by the frame-like heat around the base material (hereinafter referred to as non-thermal melting) 10) is provided, and the part 20 melted by the heat of the base material 2 is visible.
In the present embodiment, a laminated base material of the nonwoven fabric 3 and the film 4 is used as the base material 2, but an embodiment in which the nonwoven fabric 3 is a single base material can also be implemented.

FIG. 2 is obtained by changing the pattern of the heat-melting portion and the non-heat-melting portion from that in FIG. 1, and the other portions are the same as those in the embodiment of FIG.
In the embodiment of FIG. 2a), the proportion of the thermal melting portion 20 occupying the entire base material is larger than that of the embodiment of FIG. 1, and the non-thermal melting portion 10 is substantially framed as a whole at the four corners around the base material. It is formed so as to be in a shape.
In the embodiment of b) in FIG. 2, a rectangular heat melting part 20 is provided at the center of the base material, and non-thermal melting parts 10 are provided on two opposite sides around the base material.
The embodiment of c) in FIG. 2 is a mode in which a plurality of heat-melting portions 20 are provided substantially at the center of the substrate, and the non-heat-melting portion 10 is formed in a substantially net shape over the entire substrate.

3 and 4 show a tape-like patch, which is in the form of a roll in this embodiment. In the embodiment of FIG. 3, a portion 20 melted by heat continuous in the longitudinal direction of the patch and a portion 10 not melted by heat continuous at both edges in the longitudinal direction of the patch are provided. In this embodiment, the pressure-sensitive adhesive protective layer is not provided, and the pressure-sensitive adhesive layer 5 is temporarily attached to the back surface of the substrate 2 (the surface opposite to the surface on which the pressure-sensitive adhesive layer is formed) so as to be peelable.
The embodiment of FIG. 4 is substantially the same as the embodiment of FIG. 3, but differs in that the adhesive protective layer 6 is provided and the mode of the portion 10 not melted by heat. That is, in the embodiment of FIG. 4, a portion 10 that is not melted by heat at intervals is provided in a direction perpendicular to the longitudinal direction of the patch, and a plurality of portions 20 that are melted by heat in one roll are continuously provided. It is a place formed. The embodiment of FIG. 4 can be used, for example, by separating the cut line 7 so that the part 10 not melted by heat forms a frame around the base material.

In the present invention, it is preferable that the heat melting portion of the fiber base is formed in a film shape at a substantially central portion of the fiber base, and the non-heat melting portion is provided in a part or all of the periphery of the heat melting portion. The non-thermal melting part is preferably provided in a portion of 50% or more around the thermal melting part, and more preferably provided in the entire circumference of the thermal melting part.
The non-heat-melting part of the fiber base material can be provided in a frame shape around the fiber base material, or can be provided in a net shape around the fiber base material, and is preferably provided in a frame shape around the fiber base material. The non-thermal melted portion provided in a frame shape around the fiber base material preferably extends over the entire periphery of the fiber base material, but may lack a part of the frame.
In order to improve visibility, the heat-melting part of the fiber base material is preferably formed into a film and has a certain size, and 16 to 85% of the entire area of the fiber base material is the heat-melting part. It is more preferable that 32 to 80% of the total area of the fiber base material is the heat melting part. Alternatively, a large number of relatively small heat-melting portions may be gathered, and the fiber base material may be melted by heat so that the gathered portion has a planar shape as a whole.
Moreover, the heat-melting part of a fiber base material may exist in multiple places in a base fiber, and it is preferable that the area of one heat-melting part in that case is 1 cm < ² > or more from a viewpoint of visibility, More preferably, it is 4 cm ² or more. Furthermore, it is preferable from a viewpoint of visibility that the area of one heat-melting part occupies a region of 8% or more with respect to the area of the entire fiber base material.

(About fiber base materials)
The patch of the present invention has an adhesive layer on at least one surface of a substrate, and the substrate uses at least a fiber substrate such as a nonwoven fabric, a knitted fabric, or a woven fabric made of a thermoplastic resin. . Among these, it is preferable to use a non-woven fabric as a base material in which a uniform film layer is easily formed when melted by heat.
Examples of the thermoplastic resin used as the fiber base material include polyesters such as polyethylene terephthalate and polybutylene terephthalate; polyurethanes; polyolefins such as polyethylene and polypropylene; ethylene / vinyl acetate copolymers (EVA) and ethylene / ethyl acrylate copolymers. Olefins such as (EEA), ethylene / methyl acrylate copolymer (EMA), ethylene / methyl methacrylate copolymer (EMMA), ethylene / methacrylic acid polymer (EMAA), ethylene / acrylic acid copolymer (EAA) Copolymers; Polyamides such as nylon 6 and nylon 66; polystyrenes; silicones and the like. Basically, these materials are preferably used alone, but two or more types may be mixed and used. Among them, a polyester elastomer and a polyurethane elastomer having moisture permeability and stretchability are preferable, and a polyester elastomer is particularly preferable.

(Physical properties of fiber base material)
In the present invention, it is preferable that the basis weight of the fiber base material is 10 to 150 g / m ^2, and still more preferably from 10 to 100 g / m ^2. If the basis weight is lower than 10 g / m ² , the strength of the substrate is not sufficient, and there is a possibility that it will be broken by repeated friction during use. On the other hand, if the basis weight is higher than 150 g / m ² , it becomes bulky and uncomfortable when affixed to the skin, the followability to a curved surface portion is deteriorated, and melting by heat may be difficult.
In the present invention, the thickness of the fiber base material is preferably 15 to 1,000 μm, and more preferably 15 to 400 μm.

(About laminated substrates with film)
The substrate of the medical patch of the present invention is preferably a laminated substrate obtained by laminating a film substrate on the above fiber substrate. By laminating the film base material on the fiber base material, it is possible to prevent water and microorganisms from the outside from entering the affected part. As a method of laminating the fiber base material and the film, thermal lamination, laminating with an adhesive, or the like can be used.
Examples of the film base material used for the laminated base material include the same thermoplastic resins that can be used as the above-mentioned fiber base material. Among them, a polyester elastomer and a polyurethane elastomer having moisture permeability are preferable. These materials may be used alone or in combination of two or more. Further, the laminated film may be a single layer or two or more layers.
In the present invention, it is preferable that the basis weight of the film substrate to be laminated with the fibrous base material is 5 to 150 g / m ^2, and still more preferably from 5 to 50 g / m ^2.
In this invention, it is preferable that the thickness of the film base material laminated | stacked with a fiber base material is 1-1000 micrometers, and 5-150 micrometers is further more preferable.

(About general substrates)
In this invention, it is preferable that the elongation rate of a base material (The fiber base material which consists of thermoplastic resins or the lamination base material of the fiber base material which consists of thermoplastic resins, and a film base material) is 40 to 1,500%. If the elongation percentage of the base material is less than the above lower limit, the base material may not easily follow the extension of the skin and may cause a sense of incongruity during application, and the buffering ability against stress from the outside or the skin may also be reduced. . On the other hand, if the elongation percentage of the base material is larger than the above upper limit, the base material may be easily wrinkled or twisted during use.
In addition, an antioxidant, an antistatic agent, an inorganic filler, a lubricant, a pigment, a dye, an antibacterial agent, and the like can be added to the resin material used for the substrate to the extent that the object of the present invention is not impaired.

(About adhesive layer)
The patch of the present invention has an adhesive layer on at least one surface of the substrate. Depending on the application, a pressure-sensitive adhesive layer may be provided on the other surface of the base material to form a double-sided adhesive patch. When a laminated substrate is used as the substrate, the pressure-sensitive adhesive layer may be provided on either the fiber substrate side or the film substrate side. Examples of the pressure-sensitive adhesive to be used include silicone-based, acrylic-based, rubber-based, and urethane-based adhesives. Silicone-based and acrylic-based materials having good heat resistance are preferable, and silicone-based is particularly preferable. Furthermore, these adhesives, the added hydrophilic substance, if a so-called hydrocolloid pressure-sensitive adhesive, it is possible to absorb the exudate from sweat or wound, it is possible to reduce the rash and itching due to stuffiness.
In the present invention, the pressure-sensitive adhesive used is preferably visible when used as a patch, and is preferably transparent or translucent. The pressure-sensitive adhesive preferably has a light transmittance (wavelength 550 nm) of 10% or more, and more preferably 15% or more.
In this invention, it is preferable that the thickness of an adhesive layer is 10-500 micrometers, and it is still more preferable that it is 10-200 micrometers. Further preferably in the range of the coating in terms of the weight 10 to 500 g / m ² of adhesive, more preferably in the range of 20 to 150 g / m ^2. When the thickness of the pressure-sensitive adhesive layer is within this range, an appropriate adhesive force is exhibited at the time of sticking, the adhesiveness to the body surface or the like is excellent, and good moisture permeability can be obtained.

(Production method)
Next, the manufacturing method of the medical adhesive patch of this invention is demonstrated. As a method for producing the medical patch of the present invention, the following two methods can be generally used.
1) A pressure-sensitive adhesive layer is provided on a base material, and then a heat source is brought into contact with a predetermined part that requires formation of a heat melting part from the base material side (side on which the pressure-sensitive adhesive layer is not provided) A method of forming a heat melting part in a part and forming a non-heat melting part around the heat melting part.
2) A heat source is brought into contact with a predetermined portion of the base material that requires the formation of a heat melting portion, and a heat melting portion is formed on a part of the fiber base material, and a non-heat melting portion is formed around the heat melting portion. And then providing a pressure-sensitive adhesive layer on the substrate.

A specific method for producing the medical patch of the present invention is as follows.
Examples of the method of providing the pressure-sensitive adhesive layer on the substrate include a method of directly applying the pressure-sensitive adhesive on the substrate, a method of applying the pressure-sensitive adhesive to the pressure-sensitive adhesive protective layer, and affixing it to the substrate. .
The method of applying the adhesive to the base material or adhesive protective layer is not particularly limited, and the coating pattern and thickness are controlled using a known coating method such as comma direct, knife coater, or gravure direct. can do. As the coating pattern of the pressure-sensitive adhesive layer, the surface of the substrate may be partially covered or the entire surface may be covered, and any form such as a lattice shape, a net shape, a granular shape, an arabesque pattern, etc. is selected. it can.
In the patch of the present invention, the base material may be subjected to surface treatment or primer treatment in order to improve the adhesion between the base material and the pressure-sensitive adhesive layer. Examples of the surface treatment of the substrate include embossing, sand mat processing, corona discharge treatment, plasma treatment, and alkali treatment.

As a method for melting a fiber base material into a film, known heat processing methods such as heat sealing, impulse sealing, ultrasonic sealing (ultrasonic welding), and high frequency sealing (high frequency welding) can be used. The method is preferred. When heat sealing is used, a mold having a shape to be melted is attached to a hot press apparatus, and the substrate is applied at a temperature of 150 to 250 ° C., a pressure of 19.5 to 50 N / cm ² , and a pressing time of about 0.2 to 10 seconds. By bringing the mold into contact with each other, a desired position and size of the base material is melted by heat to form a portion having visibility.
In addition, in the manufacturing method of 1) above, when a patch having a predetermined shape such as a quadrangle or a circle is manufactured, an adhesive layer is continuously provided on a substrate continuously extending in a specific direction, and the continuous base A method can be used in which a heat source is brought into contact with the base material at the same time as punching the adhesive material of a predetermined shape from the material, and the fiber base material can be melted and the adhesive material can be punched at a time. Particularly preferred.

(Characteristics of medical patch)
Thus, the obtained medical patch of the present invention preferably has a transparent or translucent portion where the fiber substrate of the patch is melted by heat, and the fiber substrate of the patch is heated. The visible light transmittance (wavelength 550 nm) of the melted portion is preferably 10% or more, and more preferably 15% or more. Good visibility can be obtained when the visible light transmittance of the patch at the part melted by heat is 10% or more.
In the medical patch of the present invention, the stiffness of the portion not melted by heat is preferably 10 to 40 mm / 20 mm, and more preferably 15 to 35 mm / 20 mm. When the bending resistance is in this range, it is easy to handle before sticking to the skin, and there is little discomfort after sticking to the skin. In addition, the bending resistance of the part melted by heat of the medical patch is preferably lower than the bending resistance of the part not melted by heat, and is preferably 20 mm / 20 mm or less.
In the medical patch of the present invention, the tensile load at 40% displacement is preferably 10.0 N / 25 mm or less, and more preferably in the range of 1.0 to 10.0 N / 25 mm. When the tensile load at 40% displacement is 10.0 N / 25 mm or less, the medical patch of the present invention follows the skin stretch well and gives a sense of incongruity and physical irritation during application to the skin. There is no. If the thickness is less than 1.0 N / 25 mm, the medical patch may be more easily wrinkled and may be difficult to handle during application.

The form of the medical patch of the present invention is not particularly limited, and is a polygon such as a triangle, a quadrangle, a rhombus, a circle, an ellipse, or a sheet-like form obtained by appropriately combining these forms, or in a specific direction. A continuously manufactured roll form can be used.
Moreover, in order to protect the adhesive layer, the medical patch of the present invention may be provided with a removable adhesive protective layer on the surface of the adhesive layer, if desired. As the pressure-sensitive adhesive protective layer, a film made of polyester, polyethylene, polypropylene or the like, a film which has been subjected to a release treatment with a silicone release agent, fluorine, a fluorine compound, or the like can be used. Moreover, you may provide unevenness, such as embossing, in these protective films.
In addition, even without an adhesive protective layer, the adhesive layer of a continuously produced patch can be temporarily attached to the back of the substrate (the side opposite to the side where the adhesive layer of the substrate is present). And it can also be made into a roll form.

  EXAMPLES Hereinafter, although this invention is demonstrated further in detail based on an Example, this invention is not limited to these. Each characteristic of the patch was evaluated by the following method.

[Area ratio of fiber base material melted by heat]
The ratio of the area of the part melted by heat to the area of the entire fiber substrate was calculated. In addition, when embossing, many small heat-melted portions are scattered and each point portion does not have visibility, the point portion is assumed to be a portion melted by heat. It was decided not to calculate. However, when a large number of relatively small heat-melting parts are gathered and formed into a film so that the gathered part is planar as a whole, the whole planar part is regarded as a part melted by heat. It was decided.

[Visible light transmittance]
Using a UV-visible spectrophotometer (manufactured by Shimadzu Corporation, UV-1650PC), the transmittance of the patch at a wavelength of 550 nm was measured.

[Visibility of the patch]
Whether or not the surface portion of the adherend can be visually recognized through the adhesive material when the adhesive material was applied was evaluated in three stages: clearly visible, slightly visible Δ, and invisible.
As the adherend, paper having a blue grid line drawn on a black background was used. A plan view of the adherend is shown in FIG. Moreover, the figure which shows the result of having evaluated the visibility of a patch by affixing a patch on the said adherend and seeing a patch from the front side is shown to FIGS. 7-2-FIGS. 7-8.

[Flexibility of adhesive material]
In accordance with JIS L 1096 “Bending / softening A method (45 ° cantilever method)”, the bending / softening property of the patch was evaluated.

[Tensile load at 40% displacement of the patch]
According to JIS Z 0237 “Tensile strength and elongation”, the load (N / 25 mm) at the time of 40% displacement of the patch was measured.

[Example 1]
A silicone pressure-sensitive adhesive layer coated on a release paper at a thickness of 70 μm on a laminated base material (weight per unit area: 70 g / m ² ) by embossing of a thermoplastic polyester elastomer film and a thermoplastic polyester elastomer non-woven fabric (Unicel R860). It bonded together on the film side of the base material. Thereafter, a circular mold heated to 195 ° C. is pressed against the center of the adhesive material from the nonwoven fabric side for 7 seconds to form a nonwoven fabric portion of the base material, and the medical adhesive material of the present invention as shown in FIG. Obtained. The non-filmed portion of the nonwoven fabric was formed in a frame shape around the patch. The results of evaluating each characteristic are shown in FIG. Moreover, the figure which shows the result of having evaluated visibility about the adhesive material of a present Example is shown to FIGS. 7-2. According to FIG. 7-2, the lattice lines of the adherend can be clearly observed in the upper left heat melting portion, but the other non heat melting portions have the embossing in spite of the embossing. It can be seen that almost no lattice lines can be observed.

[Example 2]
A silicone pressure-sensitive adhesive layer coated on a release paper with a thickness of 70 μm was bonded to an embossed thermoplastic polyester elastomer nonwoven fabric base material (Nyuberan R668 manufactured by Unicel) (weight per unit area: 80 g / m ² ). Thereafter, the nonwoven fabric was formed into a film under the same conditions as in Example 1 to obtain the medical patch of the present invention. The non-filmed portion of the nonwoven fabric was formed in a frame shape around the patch. The results of evaluating each characteristic are shown in FIG. Moreover, the figure which shows evaluation of the visibility of a patch is shown to FIGS. 7-3.

Example 3
A medical patch of the present invention was obtained in the same manner as in Example 1 except that an acrylic adhesive coated on a release paper with a thickness of 60 μm was used as the adhesive layer. The results of evaluating each characteristic are shown in FIG. Moreover, the figure which shows the visibility evaluation of a patch is shown to FIGS. 7-4.

Example 4
An acrylic pressure-sensitive adhesive layer applied on a release paper at a thickness of 50 μm was bonded to a thermoplastic polyurethane elastomer nonwoven fabric substrate (Microflex UC0050 manufactured by Kuraray Co., Ltd.) (weighing 50 g / m ² ). Thereafter, the nonwoven fabric was formed into a film under the same conditions as in Example 1 to obtain the medical patch of the present invention. The non-filmed portion of the nonwoven fabric was formed in a frame shape around the patch. The results of evaluating each characteristic are shown in FIG. Moreover, the figure which shows evaluation of the visibility of a patch is shown to FIGS. 7-5.

Example 5
A laminated base material (weight per unit of 60 g / m ² ) obtained by laminating an embossed thermoplastic polyurethane elastomer non-woven base material (Espancione manufactured by KB Seiren Co., Ltd.) and a polyurethane film base material with a urethane-based adhesive. An acrylic pressure-sensitive adhesive layer applied at a thickness of 40 μm was bonded to the film side of the substrate. Thereafter, a circular mold heated to 190 ° C. was pressed against the center of the adhesive material for 7 seconds from the nonwoven fabric side, and the nonwoven fabric portion of the substrate was formed into a film to obtain the medical adhesive material of the present invention. The non-filmed portion of the nonwoven fabric was formed in a frame shape around the patch. The results of evaluating each characteristic are shown in FIG. Moreover, the figure which shows the visibility evaluation of a patch is shown to FIGS. 7-6.

[Comparative Example 1]
Acrylic adhesive coated on release paper with a thickness of 50 μm on a laminated base material (weight per unit of 55 g / m ² ) obtained by laminating a composite non-woven fabric (Elves manufactured by Unitika Ltd.) with a polyethylene core and a polyethylene film by hot embossing. The agent layer was bonded. The result of evaluating each characteristic is shown in FIG. Moreover, the figure which shows evaluation of the visibility of a patch is shown to FIGS. 7-7. In this case, the lattice lines of the adherend cannot be visually recognized.

[Comparative Example 2]
A silicone adhesive applied on a release paper at a thickness of 70 μm was bonded to a laminated base material (weight per unit 42 g / m ² ) of a polyester nonwoven fabric (manufactured by Vilene LMW9004 / PET2) and a polyester film. A mold heated to 220 ° was pressed against this central portion for 7 seconds, but the nonwoven fabric was not melted because it was not a thermoplastic resin. The result of evaluating each characteristic is shown in FIG. Moreover, the figure which shows the visibility evaluation of a patch is shown to FIGS. 7-8. Also in this case, the lattice lines of the adherend cannot be visually recognized.

  As described above, according to the embodiment of the present invention, it can be seen that a relatively wide area portion can be visualized by a relatively simple method. Moreover, the following can be said including the results of FIGS.

Visibility is not imparted by mere embossing (see the portions of Examples 1 to 3 and 5 where heat welding is not performed, Comparative Example 1).
When a non-thermoplastic non-woven fabric is used, film formation does not occur even after heat treatment, and visibility is not imparted (see Comparative Example 2).
On the other hand, the adhesive material of the present invention has good visibility, and by using a base material having a predetermined tensile load and bending resistance, it is easy to handle and has no sense of incongruity when applied to the skin. there were.

The figure of the patch which concerns on an example of embodiment of this invention. The figure of the patch which concerns on an example of other embodiment of this invention. The figure of the patch which concerns on an example of other embodiment of this invention. The figure of the patch which concerns on an example of other embodiment of this invention. The figure which shows the evaluation result of the Example of this invention. The figure which shows the evaluation result of the comparative example of this invention. The top view of the to-be-adhered body used for evaluation of visibility of this invention. The figure which shows evaluation of the visibility of Example 1 of this invention. The figure which shows evaluation of the visibility of Example 2 of this invention. The figure which shows evaluation of the visibility of Example 3 of this invention. The figure which shows evaluation of the visibility of Example 4 of this invention. The figure which shows evaluation of the visibility of Example 5 of this invention. The figure which shows the evaluation of the visibility of the comparative example 1 of this invention. The figure which shows the evaluation of the visibility of the comparative example 2 of this invention.

Explanation of symbols

DESCRIPTION OF SYMBOLS 1 Adhesive material 2 Base material 3 Nonwoven fabric 4 Film 5 Adhesive layer 6 Adhesive protective layer 7 Cut line 10 The part which is not melted by heat (non-thermal melting part)
20 The part melted by heat (heat melting part)

Claims (9)

  In a medical patch having an adhesive layer on at least one surface of a substrate, the substrate is a fiber substrate made of a thermoplastic resin or a laminated substrate of a fiber substrate made of a thermoplastic resin and a film substrate. The fiber base material includes a part melted by heat (heat melting part) and a part not melted by heat (non-heat melting part) around a part of the heat melting part (non-heat melting part). A medical patch characterized by the fact that the fusion site is visible in the melting part.   The medical patch according to claim 1, wherein the non-thermally melted portion provided on the fiber base material has a frame shape around the base material.   The medical patch according to any one of claims 1 and 2, wherein the heat-melting portion is 16 to 85% of the entire area of the fiber base material. The medical patch according to any one of claims 1 to 3, wherein the area of one heat melting part is 1 cm ² or more.   The medical patch according to any one of claims 1 to 4, wherein the bending resistance of the patch at the non-heat-melting portion is 10 to 40 mm / 20 mm.   The medical patch according to any one of claims 1 to 5, wherein the visible light transmittance (wavelength 550 nm) of the heat melting portion is 10% or more.   The medical patch according to any one of claims 1 to 6, wherein the substrate is a nonwoven fabric or a laminated substrate containing a nonwoven fabric.   The medical adhesive patch according to any one of claims 1 to 7, wherein the adhesive layer comprises a transparent or translucent adhesive.   In a method for producing a medical patch having an adhesive layer on at least one surface of a substrate, the substrate is adhered to a fiber substrate made of a thermoplastic resin or a laminated substrate of a fiber substrate made of a thermoplastic resin and a film substrate. Next, a heat source is contacted from the base material side, and a part of the fiber base material melted by heat is formed on a part of the fiber base material. A method for producing a medical patch, characterized by being formed as follows.