JP2008013504A - Oily cosmetic - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide an oily cosmetic which has a surfactant concentration of 15 to 60 mass%, has low assimilability against acne bacteria in spite of the high concentration, hardly causes pimples, is low in skin irritation, and has high safety. <P>SOLUTION: This oily cosmetic is characterized by comprising a polyglyceryl fatty acid ester type nonionic surfactant, a polyoxyethylene glyceryl fatty acid type nonionic surfactant, and a polyoxyethylene fatty acid glyceryl type nonionic surfactant, wherein the surfactants are contained in an amount of 15 to 60 mass% based on the total amount of the oily cosmetic. <P>COPYRIGHT: (C)2008,JPO&INPIT

Description

  The present invention relates to an oily cosmetic that is hypoallergenic and low-efficiency against acne bacteria despite a high surfactant-containing concentration.

  Conventionally, many oil-based cleansing agents have been proposed as makeup removers due to their excellent cleaning effect, and various products have been put on the market. Among these, cleansing cosmetics (see Patent Document 1) containing a specific nonionic surfactant, water and a liquid oil as essential components, a specific nonionic surfactant, a hydrophobic group and a polar group in the molecule. Oil-based skin cleanser (see Patent Document 2), which contains a compound having a liquid and a liquid oil as essential components, an oily component containing a specific amount of a fatty acid ester having a branched chain in the molecule, and a polyvalent alcohol having three or more hydroxyl groups -Oil, detergents containing a specific nonionic surfactant (see Patent Document 3), oily cosmetics containing grape seed oil (see Patent Document 4), and the like have been proposed.

  Other proposals other than makeup remover include oil-containing compositions containing a specific nonionic surfactant, water and liquid oil as essential components (see Patent Document 5), and specific alkyl phosphate ester-based interfaces. An active agent, a liquid oil, water and a polyhydric alcohol as essential components, a transparent skin cosmetic (see Patent Document 6), a specific hydrophilic surfactant and a water-soluble substance having a hydroxyl group in the molecule A liquid crystal structure containing oily components and water as essential components as a base (see Patent Document 7) has been proposed.

  The oil bath agent is used for the purpose of imparting a moist feeling to the skin after bathing, in addition to the aromatherapy effect by aroma. The oil bathing agent is based on the state of dissolution and dispersion of oil during use (a) floating bath type (floating on the surface as oil droplets), (b) spreading bath type (spreading as an oil film), (c) dispersion There are four types, bath type (oil component becomes fine particles and dispersed in bath water), and (d) milk bath type (oil component is dispersed in white turbidity in bath water). Of these, the milk bath type is preferred because it is smooth and non-sticky. A milk bath is composed of an oil component and a surfactant, and in many cases, a high-concentration surfactant is blended in order to disperse white turbidity in a large amount of hot water. (See Non-Patent Document 1)

Japanese Patent Laid-Open No. 3-161428 JP 11-35421 A JP 2001-342115 A JP 2003-0470730 A JP-A-1-238518 Japanese Examined Patent Publication No. 7-78009 JP-A-1-53845 Edited by Takeo Mitsui, “New Cosmetics”, 2nd edition, Nanzan-do, January 18, 2001, p. 520-521

  However, the oil cleansing and oil bath preparations described above have a drawback that they tend to cause acne because they contain a large amount of oil. In addition, there is a drawback in that it is difficult to ensure the safety to the skin because the amount of the surfactant is apt to increase in order to improve the washability, cleansing power, and cloudiness stability.

  Therefore, in the present invention, despite the high surfactant concentration of 15 to 60% by mass, it is less assimilated to acne bacteria and less likely to acne, and has low irritation to skin and high safety. The object was to obtain an oily cosmetic composition having

  In preparing oily cosmetics, the present inventors incorporated a specific nonionic surfactant in combination, so that the surfactant concentration is as high as 15 to 60% by mass, It has been found that an oily cosmetic material having low safety to acne and less acne, and having low skin irritation and high safety can be obtained.

  The oily cosmetic composition of the present invention comprises a polyglycerin fatty acid ester type nonionic surfactant, a polyoxyethylene glyceryl fatty acid ester type nonionic surfactant, and a polyoxyethylene fatty acid glyceryl type nonionic surfactant. It contains 15-60 mass% with respect to oily cosmetics whole quantity, It is characterized by the above-mentioned.

  Further, in the oily cosmetic composition of the present invention, the polyoxyethylene glyceryl fatty acid ester type nonionic surfactant has a liquid or paste-like appearance at room temperature, so that elongation at the time of use and skin familiarity are good. Become.

  According to the present invention, although the surfactant concentration is as high as 15 to 60% by mass, the assimilation property against acne bacteria is low and acne is difficult to occur, and the skin irritation is low and the safety is high. Oily cosmetics can be provided.

  Hereinafter, embodiments of the present invention will be described in detail. First, each component of the oily cosmetic of the present invention will be described.

  The oily cosmetic of the present invention contains a polyglycerin fatty acid ester type nonionic surfactant, a polyoxyethylene fatty acid ester type nonionic surfactant, and a polyoxyethylene fatty acid glyceryl type nonionic surfactant.

  As the polyglycerin fatty acid ester type nonionic surfactant, the polyglycerin fatty acid ester type nonionic surfactant is preferably an ester of polyglycerin having a polymerization degree of 3 to 15 and a fatty acid having 8 to 22 carbon atoms. Examples of such polyglycerol fatty acid esters include tetraglycerol monolaurate, hexaglycerol monolaurate, pentaglycerol monolaurate, decaglycerol monolaurate, pentaglycerol monomyristate, decaglycerol monomyristate, hexaglycerol monostearate. Acid ester, hexaglycerin sesquistearic acid ester, decaglycerin monostearic acid ester, decaglycerin distearic acid ester, decaglycerin tristearic acid ester, hexaglycerin monoisostearic acid ester, decaglycerin monoisostearic acid ester, decaglycerin diisostearic acid ester, Decaglycerin monocapric acid ester, hexag Serine monooleate, pentaglycerol monooleate, decaglycerol monooleate and the like. Among these, tetraglycerin monolaurate, hexaglycerin monolaurate, decaglycerin monolaurate and the like are exemplified, and among these, use of decaglycerin monolaurate is preferable from the viewpoint of utilization against acne bacteria.

  As a compounding quantity to the oily cosmetics of a polyglyceryl fatty acid ester type nonionic surfactant, 1-20 mass% is preferable. When the amount is less than 1% by mass, there is a possibility that the assimilation property against acne bacteria becomes high. Moreover, even if it mixes exceeding 20 mass%, the improvement of the assimilation with respect to an acne microbe will not be recognized.

  The polyoxyethylene glyceryl fatty acid ester nonionic surfactant has a structure in which a fatty acid is ester-bonded to polyoxyethylene glyceryl, and includes a monoester, a diester, and a triester. In the present invention, a triester is preferably used from the viewpoint of cleansing force. As fatty acids to be ester-bonded, fatty acids having 8 to 22 carbon atoms are used. For example, octanoic acid, 2-ethylhexanoic acid, decanoic acid, lauric acid, myristic acid, palmitic acid, isostearic acid, stearic acid, oleic acid, behenine Of these, among them, 2-ethylhexanoic acid, isostearic acid, and oleic acid can be used to obtain a liquid or pasty hydrophilic polyoxyethylene fatty acid ester nonionic surfactant at room temperature. This is preferable from the viewpoint of elongation on the skin. The degree of polymerization of ethylene oxide (hereinafter abbreviated as EO) is preferably from 5 to 60 in terms of a refreshing feeling after use. Specifically, polyoxyethylene (3) glyceryl trioleate, polyoxyethylene (5) glyceryl trioleate, polyoxyethylene (10) glyceryl trioleate, polyoxyethylene (20) glyceryl trioleate, trio Polyoxyethylene (30) glyceryl oleate, polyoxyethylene trioleate (40) glyceryl, polyoxyethylene trioleate (50) glyceryl, polyoxyethylene trioleate (60) glyceryl, polyoxyethylene triisostearate ( 3) Glyceryl, polyoxyethylene triisostearate (5) glyceryl, polyoxyethylene triisostearate (10) glyceryl, polyoxyethylene triisostearate (20) glyceryl, triisostearate Polyoxyethylene (30) glyceryl phosphate, polyoxyethylene (40) glyceryl triisostearate, polyoxyethylene (50) glyceryl triisostearate, polyoxyethylene (60) glyceryl triisostearate, polyoxyethylene diisostearate (10 ) Glyceryl, polyoxyethylene diisostearate (20) glyceryl, polyoxyethylene diisostearate (30) glyceryl, polyoxyethylene diisostearate (60) glyceryl, polyoxyethylene isostearate (3) glyceryl, polyoxyethylene isostearate (5 ) Glyceryl, polyoxyethylene isostearate (6) glyceryl, polyoxyethylene isostearate (8) glyceryl, isostearate Polyoxyethylene (10) glyceryl, polyoxyethylene (15) glyceryl isostearate, polyoxyethylene (20) glyceryl isostearate, polyoxyethylene (isostearate) (25) glyceryl, polyoxyethylene (30) glyceryl isostearate, isostearic acid Examples include polyoxyethylene (40) glyceryl, polyoxyethylene (50) glyceryl isostearate, and polyoxyethylene (60) glyceryl isostearate. In the oily cosmetics of the present invention, cleansing can be achieved by selecting those having different HLB values by using in combination two or more polyoxyethylene glyceryl fatty acid ester type nonionic surfactants having different oxyethylene chain lengths. It is possible to obtain an oily cosmetic with a good feeling of use, in which both strength, moist feeling and a refreshing feeling after washing away are compatible.

  The blending amount of the poxyethylene glyceryl fatty acid ester type nonionic surfactant into the oily cosmetic is preferably 1 to 40% by mass. When the amount is less than 1% by mass, cleansing power and a refreshing feeling after washing off may be reduced, or when dispersed in oil, the oil may not float uniformly and cause oil floating.

  The polyoxyethylene fatty acid glyceryl type nonionic surfactant is not particularly limited as long as it can be usually blended into a skin external preparation. It is produced by adding ethylene oxide to a glycerin fatty acid ester obtained by reacting 1 to 2 mol of a fatty acid with respect to 1 mol of glycerin. The fatty acid used is a linear or branched fatty acid having 8 to 24 carbon atoms, and the average number of moles of ethylene oxide added is 5 to 80. For example, polyoxyethylene (20) glyceryl monolaurate, polyoxyethylene (7) mono coconut oil fatty acid glyceryl, polyoxyethylene (30) mono coconut oil fatty acid glyceryl, polyoxyethylene (80) mono tallow fatty acid glyceryl, polyoxyethylene (3 ) Glyceryl isostearate, polyoxyethylene (5) glyceryl isostearate, polyoxyethylene (6) glyceryl isostearate, polyoxyethylene (8) glyceryl isostearate, polyoxyethylene (10) glyceryl isostearate, polyoxyethylene (15 ) Glyceryl isostearate, polyoxyethylene (20) Glyceryl isostearate, polyoxyethylene (25) Glyceryl isostearate, polyoxyethylene (7) Capric / caprylic acid) glyceryl, mono [polyoxyethylene (20) isostearate] glyceryl di [polyoxyethylene (20) glyceryl isostearate, and the like.

  As a compounding quantity to the oily cosmetics of polyoxyethylene fatty acid glyceryl type nonionic surfactant, 1-40 mass% is preferable. If the blending amount is less than 1% by mass, cleansing power and a refreshing feeling after washing off may be reduced, or when dispersed in hot water, the oil may not float uniformly and cause oil floating.

  In the oily cosmetic composition of the present invention, a polyglycerin fatty acid ester type nonionic surfactant, a polyoxyethylene glyceryl fatty acid ester type nonionic surfactant, and a surfactant other than the polyoxyethylene fatty acid glyceryl type nonionic surfactant Does not prevent you from doing.

  The oily cosmetic of the present invention contains 15 to 60% by mass of a surfactant based on the total amount of the oily cosmetic. When the blending amount is less than 15% by mass, it may be difficult to obtain a sufficient cleansing power, or white turbidity in hot water may not be sufficient and may cause oil floating. If it exceeds 60% by mass, it may cause skin irritation or a moist feeling.

  The oily cosmetic of the present invention can contain purified water in order to make the appearance transparent. As a compounding quantity of purified water, the compounding of 0.05-10 mass% is preferable on the property of oily cosmetics.

  The oily cosmetic composition of the present invention is provided in a liquid form or a gel form with the addition of a gelling agent. The gelling agent is not particularly limited as long as it is usually blended as a gelling agent for oily cosmetics. For example, metal soaps such as aluminum stearate and magnesium stearate, sucrose palmitate, starch palmitic acid Ester, polysaccharide fatty acid esters such as bacmond stearate, organically modified clay minerals such as dioctadecyldimethylammonium salt modified montmorillonite, dihexadecyldimethylammonium salt modified montmorillonite, 12-hydroxystearic acid, fumed silica powder, etc. It is done.

  The oil component to be blended with the oily cosmetic composition of the present invention is not particularly limited as long as it is usually blended with the oily cosmetic composition, but it is preferable to use a liquid or paste-like composition at room temperature. Specifically, for example, squalane, α-olefin oligomer, hydrocarbons such as isoparaffin, liquid paraffin, petroleum jelly, olive oil, medofoam oil, avocado oil, almond oil, sesame oil, camellia oil, perilla oil, cottonseed oil, sunflower oil, Rapeseed oil, orange oil, grapefruit seed oil, grape seed oil, rapeseed oil, palm oil, safflower oil, jojoba oil and other vegetable oils, mink oil, egg yolk oil, horse oil, lanolins and other animal oils, dimethylpolysiloxane, methyl Examples include silicone oils such as phenylpolysiloxane, ester oils such as hexyl laurate, myristyl myristate, cetyl myristate, and cetyl ethylhexanoate. These are used alone or in combination of two or more.

  In addition, a humectant, a stabilizer, an antioxidant, a colorant, a fragrance, an anti-inflammatory agent, a bactericidal agent, an antibacterial agent, and the like may be added as long as the object and effect of the present invention are not impaired.

  The oily cosmetics of the present invention are suitably used as oily cleansing cosmetics and oily bathing agents.

  EXAMPLES Hereinafter, although an Example is given and this invention is demonstrated in more detail, this invention is not limited to these Examples.

[Example 1]
An oil-based cleansing cosmetic was prepared by uniformly mixing all components in the formulation shown in Table 1.

[Cytotoxicity test]
Human cervical cancer-derived cell line HeLa cells were seeded in a 96-well microplate at 4.0 × 10 ³ cells per well. The seeding medium was Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) and 0.03% L-glutamine as the basic medium. After anaerobic culture for 72 hours, the medium was replaced with a medium in which samples prepared at various concentrations were added to the basic medium, followed by further anaerobic culture for 48 hours. The medium was washed twice with physiological saline, and purified by contacting with 0.5 mg / mL MTT (3- [4,5-Dimethylthiazol-2-yl] -2,5-diphenyltetrazolium bromide) solution for 2 hours. Formazan was extracted with 0.04N hydrochloric acid-isopropanol and quantified by measuring absorbance at a wavelength of 590 nm. Absorbance in the absence of the test substance was taken as 100%, and the concentration showing 50% absorbance was taken as the EC50 value. Cytotoxicity tests are judged according to the criteria shown in Table 2, and the results are summarized in Table 3.

[Comparative Example 1]
(1) Glyceryl tri-2-ethylhexanoate 38.0 (mass%)
(2) Dipropylene glycol 20.0
(3) Octyldodecanol 10.0
(4) Polyoxyethylene (20) glyceryl triisostearate 10.0
(5) Dicaprylyl carbonate 10.0
(6) Polyoxyethylene (7) (capryl / capric acid) glyceryl 10.0
(7) Purified water 2.0

  From Table 3, it is clear that the examples of the present invention have higher safety compared to Comparative Example 1 which is another general cleansing oil.

[Utilization test]
Acne bacteria ( Propionibacterium acnes ) cultured in a GAM liquid medium are added to 5.2 × 10 ⁵ in an acne NYT medium containing 1% of a test substance and 9% of polyoxyethylene (20) polyoxypropylene glycol (20). The cells were seeded and cultured to give cfu / mL, and the number of remaining bacteria after 24 hours and 48 hours was counted. The cells were smeared on a modified GAM agar medium, and anaerobically cultured at 37 ° C. for 5 days. The number of appearing colonies was counted to calculate the number of remaining acne bacteria / mL. In addition, 10% of polyoxyethylene (20) and polyoxypropylene glycol (20) were added and cultured, and it was confirmed that no assimilability was exhibited against acne bacteria. Moreover, what was cultured without adding a test substance was tested simultaneously as a control.

[Comparative Example 2]
(1) Safflower oil 35.0 (mass%)
(2) Squalane 38.0
(3) Pentaerythrityl tetraoctanoate 5.0
(4) Polyoxyethylene (20) glyceryl triisostearate 20.0
(5) Purified water 2.0

[Comparative Example 3]
(1) Liquid paraffin 38.0
(2) Glyceryl tri-2-ethylhexanoate 40.0
(3) Polyisoethylene diisostearate (8) Glyceryl 18.0
(4) Polyoxyethylene (20) glyceryl lyisostearate 2.0
(5) Purified water 2.0

  As shown in Table 4, in the case of the usual cleansing oils on the market, a clear effect of promoting the growth of acne bacteria is recognized, and it is recognized that the utilization of acne bacteria is high. On the other hand, the Example of this invention did not show assimilation with respect to an acne microbe.

[Use test]
A group of 10 women in their 10s to 20s who care about acne were used once a day for 5 consecutive days, and a questionnaire regarding cleansing power, skin irritation and skin troubles was conducted. The results are shown in Table 4 in terms of the number of panelists evaluated as applicable to each item.

  As shown in Table 4, the examples of the present invention have good cleansing power, a tendency to improve acne symptoms, and high safety without skin irritation and skin troubles such as dry skin. It was to show.

  The bath preparations described in Table 5 were prepared and subjected to the same usage test as in Example 1. As a result, as shown in Table 5, the bath water was uniformly clouded, an improvement tendency was observed in acne symptoms, there was no problem in safety, and the bath had a good feeling of use that moistened the bath.

  Table 6 shows cleansing oil examples and use test results.

Claims (2)

It contains a polyglycerin fatty acid ester type nonionic surfactant, a polyoxyethylene glyceryl fatty acid ester type nonionic surfactant, and a polyoxyethylene fatty acid glyceryl type nonionic surfactant, and the surfactant concentration is 15 with respect to the total amount of the oily cosmetic. Oily cosmetics that are ˜60% by mass. The oily cosmetic according to claim 1, wherein the polyoxyethylene glyceryl fatty acid ester type nonionic surfactant is a polyoxyethylene fatty acid ester type nonionic surfactant that is liquid or pasty at room temperature.