JP2007536359A - B細胞の白血病及びリンパ腫の治療のためのltb4インヒビターの使用 - Google Patents

B細胞の白血病及びリンパ腫の治療のためのltb4インヒビターの使用 Download PDF

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JP2007536359A
JP2007536359A JP2007512321A JP2007512321A JP2007536359A JP 2007536359 A JP2007536359 A JP 2007536359A JP 2007512321 A JP2007512321 A JP 2007512321A JP 2007512321 A JP2007512321 A JP 2007512321A JP 2007536359 A JP2007536359 A JP 2007536359A
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JP
Japan
Prior art keywords
inhibitor
ltb
cells
inhibitors
biosynthesis
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Withdrawn
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JP2007512321A
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Japanese (ja)
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JP2007536359A5 (https=
Inventor
ハンス−エリック クラエッソン,
マグヌス ビョークホルム,
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Biolipox AB
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Biolipox AB
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Publication of JP2007536359A publication Critical patent/JP2007536359A/ja
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • A61K31/405Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2007512321A 2004-05-06 2005-05-05 B細胞の白血病及びリンパ腫の治療のためのltb4インヒビターの使用 Withdrawn JP2007536359A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US56826204P 2004-05-06 2004-05-06
GBGB0410103.6A GB0410103D0 (en) 2004-05-06 2004-05-06 New method
PCT/GB2005/001724 WO2005107725A1 (en) 2004-05-06 2005-05-05 Use of ltb4 inhibitors for the treatment of b-cell leukemias and lymphomas

Publications (2)

Publication Number Publication Date
JP2007536359A true JP2007536359A (ja) 2007-12-13
JP2007536359A5 JP2007536359A5 (https=) 2008-06-26

Family

ID=32482771

Family Applications (1)

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JP2007512321A Withdrawn JP2007536359A (ja) 2004-05-06 2005-05-05 B細胞の白血病及びリンパ腫の治療のためのltb4インヒビターの使用

Country Status (5)

Country Link
US (1) US20080081835A1 (https=)
EP (1) EP1742622A1 (https=)
JP (1) JP2007536359A (https=)
GB (1) GB0410103D0 (https=)
WO (1) WO2005107725A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009092087A2 (en) * 2008-01-18 2009-07-23 The Brigham And Women's Hospital, Inc. Selective differentiation, identification, and modulation of human th17 cells
US9732320B2 (en) 2008-01-18 2017-08-15 The Brigham And Women's Hospital, Inc. Selective differentiation, identification, and modulation of human TH17 cells
AU2009249258A1 (en) * 2008-05-21 2009-11-26 Teikoku Pharma Usa, Inc. Treatment of dysmenorrhea via transdermal administration of nonsteroidal anti-inflammatory drugs
GB0810011D0 (en) * 2008-06-02 2008-07-09 Jackson William P 5-Lipoxygenase inhibitors
CR20160279A (es) 2013-12-20 2016-08-31 Novartis Ag Derivados de ácido heteroaril butanóico como inhibidores de lta4h
CN115068486A (zh) * 2021-03-15 2022-09-20 中国医学科学院药物研究所 乳香酸类化合物作为ltb4受体抑制剂的用途

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0750496A1 (en) * 1994-03-14 1997-01-02 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES Use of lipoxygenase inhibitors as anti-cancer therapeutic and intervention agents
GB2290707A (en) * 1994-06-28 1996-01-10 Georgi Stankov Pharmaceutical uses of Amphotericin B
AU7855900A (en) * 1999-10-04 2001-05-10 University Of Medicine And Dentistry Of New Jersey Methods for identifying rna binding compounds
AU1917101A (en) * 1999-11-11 2001-06-06 Eli Lilly And Company Oncolytic combinations for the treatment of cancer
WO2001034134A2 (en) * 1999-11-11 2001-05-17 Eli Lilly And Company Oncolytic combinations for the treatment of cancer
AU1592901A (en) * 1999-11-11 2001-06-06 Eli Lilly And Company Oncolytic combinations for the treatment of cancer
WO2001034133A2 (en) * 1999-11-11 2001-05-17 Eli Lilly And Company Oncolytic combinations for the treatment of cancer
JP2005531498A (ja) * 2002-02-08 2005-10-20 エフ.ホフマン−ラ ロシュ アーゲー 骨減少を治療および予防する方法
JP2003252763A (ja) * 2002-02-27 2003-09-10 Yuichiro Kamikawa 抗腫瘍剤
US6962940B2 (en) * 2002-03-20 2005-11-08 Celgene Corporation (+)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione: methods of using and compositions thereof
WO2004099783A2 (en) * 2003-05-06 2004-11-18 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with g-protein-coupled receptor ltb4 (ltb4)

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Publication number Publication date
GB0410103D0 (en) 2004-06-09
EP1742622A1 (en) 2007-01-17
WO2005107725A1 (en) 2005-11-17
US20080081835A1 (en) 2008-04-03

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