JP2007536359A - B細胞の白血病及びリンパ腫の治療のためのltb4インヒビターの使用 - Google Patents

B細胞の白血病及びリンパ腫の治療のためのltb4インヒビターの使用 Download PDF

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Publication number
JP2007536359A
JP2007536359A JP2007512321A JP2007512321A JP2007536359A JP 2007536359 A JP2007536359 A JP 2007536359A JP 2007512321 A JP2007512321 A JP 2007512321A JP 2007512321 A JP2007512321 A JP 2007512321A JP 2007536359 A JP2007536359 A JP 2007536359A
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JP
Japan
Prior art keywords
inhibitor
ltb
cells
inhibitors
biosynthesis
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Withdrawn
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JP2007512321A
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Japanese (ja)
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JP2007536359A5 (enExample
Inventor
ハンス−エリック クラエッソン,
マグヌス ビョークホルム,
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Biolipox AB
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Biolipox AB
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Publication of JP2007536359A publication Critical patent/JP2007536359A/ja
Publication of JP2007536359A5 publication Critical patent/JP2007536359A5/ja
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • A61K31/405Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2007512321A 2004-05-06 2005-05-05 B細胞の白血病及びリンパ腫の治療のためのltb4インヒビターの使用 Withdrawn JP2007536359A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US56826204P 2004-05-06 2004-05-06
GBGB0410103.6A GB0410103D0 (en) 2004-05-06 2004-05-06 New method
PCT/GB2005/001724 WO2005107725A1 (en) 2004-05-06 2005-05-05 Use of ltb4 inhibitors for the treatment of b-cell leukemias and lymphomas

Publications (2)

Publication Number Publication Date
JP2007536359A true JP2007536359A (ja) 2007-12-13
JP2007536359A5 JP2007536359A5 (enExample) 2008-06-26

Family

ID=32482771

Family Applications (1)

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JP2007512321A Withdrawn JP2007536359A (ja) 2004-05-06 2005-05-05 B細胞の白血病及びリンパ腫の治療のためのltb4インヒビターの使用

Country Status (5)

Country Link
US (1) US20080081835A1 (enExample)
EP (1) EP1742622A1 (enExample)
JP (1) JP2007536359A (enExample)
GB (1) GB0410103D0 (enExample)
WO (1) WO2005107725A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110245107A1 (en) * 2008-01-18 2011-10-06 The Brigham And Women's Hospital, Inc. Selective differentiation, identification, amd modulation of human th17 cells
US9732320B2 (en) 2008-01-18 2017-08-15 The Brigham And Women's Hospital, Inc. Selective differentiation, identification, and modulation of human TH17 cells
EA201000990A1 (ru) * 2008-05-21 2011-06-30 ТЕЙКОКУ ФАРМА ЮЭсЭй, ИНК. Лечение дисменореи путем трансдермального введения нестероидных противовоспалительных лекарственных средств
GB0810011D0 (en) * 2008-06-02 2008-07-09 Jackson William P 5-Lipoxygenase inhibitors
UA117498C2 (uk) 2013-12-20 2018-08-10 Новартіс Аг Гетероарильні похідні бутанової кислоти як інгібітори lta4h
CN115068486A (zh) * 2021-03-15 2022-09-20 中国医学科学院药物研究所 乳香酸类化合物作为ltb4受体抑制剂的用途

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0750496A1 (en) * 1994-03-14 1997-01-02 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES Use of lipoxygenase inhibitors as anti-cancer therapeutic and intervention agents
GB2290707A (en) * 1994-06-28 1996-01-10 Georgi Stankov Pharmaceutical uses of Amphotericin B
US6503713B1 (en) * 1999-10-04 2003-01-07 University Of Medicine And Dentistry Of New Jersey Methods for identifying RNA binding compounds
WO2001034199A2 (en) * 1999-11-11 2001-05-17 Eli Lilly And Company Oncolytic combinations for the treatment of cancer
WO2001034204A1 (en) * 1999-11-11 2001-05-17 Eli Lilly And Company Oncolytic combinations for the treatment of cancer
WO2001034133A2 (en) * 1999-11-11 2001-05-17 Eli Lilly And Company Oncolytic combinations for the treatment of cancer
AU1595101A (en) * 1999-11-11 2001-06-06 Eli Lilly And Company Oncolytic combinations for the treatment of cancer
RU2319483C2 (ru) * 2002-02-08 2008-03-20 Ф.Хоффманн-Ля Рош Аг Способ лечения и предупреждения потери костной ткани
JP2003252763A (ja) * 2002-02-27 2003-09-10 Yuichiro Kamikawa 抗腫瘍剤
US6962940B2 (en) * 2002-03-20 2005-11-08 Celgene Corporation (+)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione: methods of using and compositions thereof
WO2004099783A2 (en) * 2003-05-06 2004-11-18 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with g-protein-coupled receptor ltb4 (ltb4)

Also Published As

Publication number Publication date
EP1742622A1 (en) 2007-01-17
US20080081835A1 (en) 2008-04-03
GB0410103D0 (en) 2004-06-09
WO2005107725A1 (en) 2005-11-17

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