JP2007533728A5 - - Google Patents
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- Publication number
- JP2007533728A5 JP2007533728A5 JP2007509007A JP2007509007A JP2007533728A5 JP 2007533728 A5 JP2007533728 A5 JP 2007533728A5 JP 2007509007 A JP2007509007 A JP 2007509007A JP 2007509007 A JP2007509007 A JP 2007509007A JP 2007533728 A5 JP2007533728 A5 JP 2007533728A5
- Authority
- JP
- Japan
- Prior art keywords
- lactalbumin
- use according
- biologically active
- variant
- virus
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 102000004407 Lactalbumin Human genes 0.000 claims 14
- 108090000942 Lactalbumin Proteins 0.000 claims 14
- 235000021241 α-lactalbumin Nutrition 0.000 claims 14
- 208000036142 Viral infection Diseases 0.000 claims 8
- 230000009385 viral infection Effects 0.000 claims 8
- 239000012634 fragment Substances 0.000 claims 7
- 241000700605 Viruses Species 0.000 claims 5
- 235000014113 dietary fatty acids Nutrition 0.000 claims 5
- 229930195729 fatty acid Natural products 0.000 claims 5
- 239000000194 fatty acid Substances 0.000 claims 5
- 150000004665 fatty acids Chemical class 0.000 claims 5
- 101000946384 Homo sapiens Alpha-lactalbumin Proteins 0.000 claims 4
- 101000946377 Bos taurus Alpha-lactalbumin Proteins 0.000 claims 3
- 230000035772 mutation Effects 0.000 claims 3
- 210000001835 viscera Anatomy 0.000 claims 3
- 102100034668 Alpha-lactalbumin Human genes 0.000 claims 2
- BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 claims 2
- 102000005701 Calcium-Binding Proteins Human genes 0.000 claims 2
- 108010045403 Calcium-Binding Proteins Proteins 0.000 claims 2
- 229960005541 HAMLET Drugs 0.000 claims 2
- 241000725643 Respiratory syncytial virus Species 0.000 claims 2
- 150000001413 amino acids Chemical class 0.000 claims 2
- 210000004556 brain Anatomy 0.000 claims 2
- 229910001424 calcium ion Inorganic materials 0.000 claims 2
- 239000005018 casein Substances 0.000 claims 2
- BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 claims 2
- 235000021240 caseins Nutrition 0.000 claims 2
- 208000015181 infectious disease Diseases 0.000 claims 2
- 102220468836 Albumin_D87N_mutation Human genes 0.000 claims 1
- 102000009027 Albumins Human genes 0.000 claims 1
- 108010088751 Albumins Proteins 0.000 claims 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims 1
- 241000711573 Coronaviridae Species 0.000 claims 1
- 241000709661 Enterovirus Species 0.000 claims 1
- 241000710781 Flaviviridae Species 0.000 claims 1
- 206010056663 Gastric infection Diseases 0.000 claims 1
- 241000700586 Herpesviridae Species 0.000 claims 1
- 206010061598 Immunodeficiency Diseases 0.000 claims 1
- 208000029462 Immunodeficiency disease Diseases 0.000 claims 1
- 208000002606 Paramyxoviridae Infections Diseases 0.000 claims 1
- 241000700625 Poxviridae Species 0.000 claims 1
- 102220467241 Receptor tyrosine-protein kinase erbB-2_D87A_mutation Human genes 0.000 claims 1
- 238000005571 anion exchange chromatography Methods 0.000 claims 1
- 229910052791 calcium Inorganic materials 0.000 claims 1
- 239000011575 calcium Substances 0.000 claims 1
- 210000001072 colon Anatomy 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 230000002496 gastric effect Effects 0.000 claims 1
- 210000001035 gastrointestinal tract Anatomy 0.000 claims 1
- 238000005227 gel permeation chromatography Methods 0.000 claims 1
- 235000020256 human milk Nutrition 0.000 claims 1
- 210000004251 human milk Anatomy 0.000 claims 1
- 230000007813 immunodeficiency Effects 0.000 claims 1
- 238000004255 ion exchange chromatography Methods 0.000 claims 1
- 210000003734 kidney Anatomy 0.000 claims 1
- 210000004185 liver Anatomy 0.000 claims 1
- 210000004072 lung Anatomy 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 235000013336 milk Nutrition 0.000 claims 1
- 239000008267 milk Substances 0.000 claims 1
- 210000004080 milk Anatomy 0.000 claims 1
- 230000004048 modification Effects 0.000 claims 1
- 238000012986 modification Methods 0.000 claims 1
- 210000001672 ovary Anatomy 0.000 claims 1
- 210000003800 pharynx Anatomy 0.000 claims 1
- 210000002307 prostate Anatomy 0.000 claims 1
- 235000018102 proteins Nutrition 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 210000002345 respiratory system Anatomy 0.000 claims 1
- 102200115883 rs121918076 Human genes 0.000 claims 1
- 230000000087 stabilizing effect Effects 0.000 claims 1
- 241000701161 unidentified adenovirus Species 0.000 claims 1
- 241000712461 unidentified influenza virus Species 0.000 claims 1
- 210000003932 urinary bladder Anatomy 0.000 claims 1
- 239000002671 adjuvant Substances 0.000 description 1
- 239000003937 drug carrier Substances 0.000 description 1
- 239000000945 filler Substances 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0408752.4A GB0408752D0 (en) | 2004-04-20 | 2004-04-20 | Therapeutic treatment |
| PCT/IB2005/001255 WO2005102382A1 (en) | 2004-04-20 | 2005-04-20 | Use of hamlet (human alpha-lactalbumin made lethal to tumour cells) for treating viral infections |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007533728A JP2007533728A (ja) | 2007-11-22 |
| JP2007533728A5 true JP2007533728A5 (https=) | 2008-06-05 |
Family
ID=32344046
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007509007A Abandoned JP2007533728A (ja) | 2004-04-20 | 2005-04-20 | ウイルス感染を治療するためのｈａｍｌｅｔ（腫瘍細胞に致死的なヒトアルファ−ラクトアルブミン）の使用 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20070232550A1 (https=) |
| EP (1) | EP1765383A1 (https=) |
| JP (1) | JP2007533728A (https=) |
| CN (1) | CN1980688A (https=) |
| GB (1) | GB0408752D0 (https=) |
| WO (1) | WO2005102382A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113855787A (zh) * | 2020-06-30 | 2021-12-31 | 北京大学 | 乳清蛋白作为冠状病毒广谱抑制剂的用途 |
| CN120860181A (zh) * | 2021-08-31 | 2025-10-31 | 合生元（广州）健康产品有限公司 | 用于抑制冠状病毒的组合物及其应用 |
| CN113827707B (zh) * | 2021-09-30 | 2023-12-05 | 北京大学 | a-乳白蛋白在抑制冠状病毒中的应用 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0210464D0 (en) * | 2002-05-08 | 2002-06-12 | Svanborg Catharina | Therapeutic treatment |
-
2004
- 2004-04-20 GB GBGB0408752.4A patent/GB0408752D0/en not_active Ceased
-
2005
- 2005-04-20 EP EP05733445A patent/EP1765383A1/en not_active Withdrawn
- 2005-04-20 CN CNA2005800192369A patent/CN1980688A/zh active Pending
- 2005-04-20 JP JP2007509007A patent/JP2007533728A/ja not_active Abandoned
- 2005-04-20 US US11/578,835 patent/US20070232550A1/en not_active Abandoned
- 2005-04-20 WO PCT/IB2005/001255 patent/WO2005102382A1/en not_active Ceased
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