JP2007524077A - 毛細管現象に基づき液体試料を操作する装置及び方法 - Google Patents
毛細管現象に基づき液体試料を操作する装置及び方法 Download PDFInfo
- Publication number
- JP2007524077A JP2007524077A JP2006520262A JP2006520262A JP2007524077A JP 2007524077 A JP2007524077 A JP 2007524077A JP 2006520262 A JP2006520262 A JP 2006520262A JP 2006520262 A JP2006520262 A JP 2006520262A JP 2007524077 A JP2007524077 A JP 2007524077A
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- JP
- Japan
- Prior art keywords
- capillary
- head
- instrument
- tip insertion
- mounting base
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/02—Burettes; Pipettes
- B01L3/0275—Interchangeable or disposable dispensing tips
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0689—Sealing
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0832—Geometry, shape and general structure cylindrical, tube shaped
- B01L2300/0838—Capillaries
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L9/00—Supporting devices; Holding devices
- B01L9/54—Supports specially adapted for pipettes and burettes
- B01L9/543—Supports specially adapted for pipettes and burettes for disposable pipette tips, e.g. racks or cassettes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N2035/1027—General features of the devices
- G01N2035/1034—Transferring microquantities of liquid
- G01N2035/1039—Micropipettes, e.g. microcapillary tubes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1065—Multiple transfer devices
- G01N35/1074—Multiple transfer devices arranged in a two-dimensional array
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/2575—Volumetric liquid transfer
Abstract
【選択図】
図1
Description
本出願は、2003年7月11日に出願された米国仮出願番号60/486479に基づく優先権を主張する。
Claims (12)
- 自動液体ディスペンサ装置用の着脱可能な毛細管先端挿入器具であって、
頭部と、
外部にネジ山を備えた軸部と、
前記頭部及び軸部の両者に渡り貫かれている管腔と、
前記軸部の末端のうち頭部側ではない末端に接続された毛細管とを備える、
ことを特徴とする器具。 - 前記毛細管は、前記毛細管の一部の周囲に前記軸部が密着するように、前記軸部の末端のうち頭部側ではない末端に接続されている、
ことを特徴とする請求項1に記載の器具。 - 前記頭部は、取付台への挿入用の器具に適合する、
ことを特徴とする請求項1に記載の器具。 - 前記頭部は、前記頭部の少なくともある部分が先細になっていることにより、前記頭部の直径が均一ではない、
ことを特徴とする請求項1に記載の器具。 - 前記毛細管の液体容量は、1ナノリットルと10,000ナノリットルの間の量である、
ことを特徴とする請求項1に記載の器具。 - 前記挿入器具の前記頭部及び前記軸部は、ポリスチレンから構成されている、
ことを特徴とする請求項5に記載の器具。 - 前記挿入器具の前記頭部及び前記軸部は、ポリプロピレンから構成されている、
ことを特徴とする請求項5に記載の器具。 - 自動液体ディスペンサ装置用の取付台であって、
1又は2以上の請求項1に記載の器具と、
該器具の形状及び外部のネジ山に合うように設計された複数の穴を備えた表面と、
1又は2以上の該器具に空気圧を与えるための1又は2以上の開口部とを備える、
ことを特徴とする取付台。 - 請求項1に記載の器具の集合体であって、前記集合体が2以上の色を備える前記集合体をさらに備える、
ことを特徴とする請求項8に記載の取付台。 - 器具の該集合体が色でコード化されている、
ことを特徴とする請求項8に記載の取付台。 - 請求項1に記載の器具の集合体であって、前記集合体が異なる液体容量を有する2以上の毛細管を備える前記集合体を備える、
ことを特徴とする請求項8に記載の取付台。 - 請求項8に記載の取付台を供給する工程と、
1又は2以上の液体試料を収容する出発基層を供給する工程と、
1又は2以上の液体試料の行先基層を供給する工程と、
自動液体ディスペンサ装置であって、
ディスペンス用のヘッドと、
出発基層と行先基層の間を周回する手段と、
1又は2以上の請求項1に記載の器具に選択的に空気圧を与える手段とを備える、
ことを特徴とする装置を供給する工程と、
前記ディスペンス用ヘッドを取付台に固定する工程と、
取付台を前記出発基層と前記行先基層の間で周回させる工程と、
を備える、ことを特徴とする液体試料の自動ディスペンス方法であって、
取付台に取り付けられた1又は2以上の器具により毛細管現象により前記出発基層から1又は2以上の試料の一部を取り出し、請求項1に記載の器具に選択的に空気圧を加えることにより前記試料の一部を行先基層にディスペンスするようにする、
ことを特徴とする液体試料の自動ディスペンス方法。
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US48647903P | 2003-07-11 | 2003-07-11 | |
PCT/US2004/022385 WO2005007289A2 (en) | 2003-07-11 | 2004-07-12 | Apparatus and methods for liquid sample handling based on capillary action |
Publications (1)
Publication Number | Publication Date |
---|---|
JP2007524077A true JP2007524077A (ja) | 2007-08-23 |
Family
ID=34079234
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2006520262A Ceased JP2007524077A (ja) | 2003-07-11 | 2004-07-12 | 毛細管現象に基づき液体試料を操作する装置及び方法 |
Country Status (4)
Country | Link |
---|---|
US (2) | US7488604B2 (ja) |
EP (1) | EP1654067A4 (ja) |
JP (1) | JP2007524077A (ja) |
WO (1) | WO2005007289A2 (ja) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7354774B2 (en) * | 2002-05-13 | 2008-04-08 | Becton, Dickinson And Company | Self aliquoting sample storage plate |
JP2009535635A (ja) * | 2006-05-03 | 2009-10-01 | エヌツェーエル ニュー コンセプト ラブ ゲーエムベーハー | 化学的、生化学的、生物学的および物理学的分析、反応、アッセイなどのためのデバイスおよび方法 |
JP4964547B2 (ja) * | 2006-09-21 | 2012-07-04 | 株式会社サカエ | 自動分析装置 |
CN101990631B (zh) * | 2008-02-15 | 2014-08-06 | 3M创新有限公司 | 样品采集装置 |
US8802030B2 (en) | 2012-02-01 | 2014-08-12 | Cybio Ag | Capillary dispenser |
DE102012100836B3 (de) * | 2012-02-01 | 2013-04-11 | Cybio Ag | Kapillardispenser |
KR20130098635A (ko) | 2012-02-28 | 2013-09-05 | 삼성전자주식회사 | 반도체 와이어 본드 공정의 캐필러리 교체시스템 |
US9095833B2 (en) | 2012-05-31 | 2015-08-04 | Biolytic Lab Performance, Inc. | System for performing automated solid phase extractions |
US20140154796A1 (en) * | 2012-12-03 | 2014-06-05 | Stanislav L. Karsten | Sampling Device and Method for Collection and Preservation of Live Cells from Tissues and Cell Cultures |
CN104918703B (zh) * | 2012-12-28 | 2017-10-10 | 阿赛斯生物股份有限公司 | 移液管 |
CH708139A2 (de) * | 2013-06-06 | 2014-12-15 | Tecan Trading Ag | Pipettiervorrichtung. |
WO2015191853A1 (en) | 2014-06-13 | 2015-12-17 | Siemens Healthcare Diagnostics Inc. | Sample delivery system |
US20160082438A1 (en) * | 2014-09-23 | 2016-03-24 | Gencell Biosystems Ltd. | Pressure based dispensing |
CN105498877A (zh) * | 2014-12-23 | 2016-04-20 | 马荣华 | 定量移液管 |
US10814320B2 (en) * | 2016-08-08 | 2020-10-27 | Nalge Nunc International Corporation | Capillary transfer pipettes and related methods |
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US5460782A (en) * | 1994-07-18 | 1995-10-24 | Safe-Tec Clinical Products, Inc. | Automatic filling micropipette with dispensing means |
JPH10311840A (ja) * | 1997-05-13 | 1998-11-24 | Horiba Ltd | 液体吸引装置 |
US6001309A (en) * | 1996-05-17 | 1999-12-14 | Incyte Pharmaceuticals, Inc. | Jet droplet device |
US6309891B1 (en) * | 1998-09-09 | 2001-10-30 | Incyte Genomics, Inc. | Capillary printing systems |
US20030086828A1 (en) * | 2001-11-05 | 2003-05-08 | Industrial Technology Research Institute | Micro-dispenser for biochemical analysis |
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US5249711A (en) * | 1992-10-01 | 1993-10-05 | Du Pont Canada Inc. | Disposable dispensing pipette |
US7285422B1 (en) * | 1997-01-23 | 2007-10-23 | Sequenom, Inc. | Systems and methods for preparing and analyzing low volume analyte array elements |
CN1315913A (zh) * | 1998-07-07 | 2001-10-03 | 笛卡尔技术公司 | 用于微量液体移液的管尖设计和随机存取系统 |
US6629626B1 (en) * | 2000-03-07 | 2003-10-07 | Dyax, Corporation | Liquid transfer device |
DE10013511A1 (de) * | 2000-03-20 | 2001-10-11 | Brand Gmbh & Co Kg | Mehrkanal-Pipettiereinrichtung sowie Pipettenschaft dafür |
JP3942363B2 (ja) * | 2001-02-09 | 2007-07-11 | 日本電子株式会社 | 透過電子顕微鏡の位相板用レンズシステム、および透過電子顕微鏡 |
JP4080893B2 (ja) | 2001-05-24 | 2008-04-23 | ニューオブジェクティブ,インク. | エレクトロスプレーをフィードバック制御するための方法と装置 |
EP1594951A2 (en) * | 2003-01-31 | 2005-11-16 | Apogent Robotics Limited | Liquid transfer system |
-
2004
- 2004-07-12 WO PCT/US2004/022385 patent/WO2005007289A2/en active Search and Examination
- 2004-07-12 EP EP04756919A patent/EP1654067A4/en not_active Withdrawn
- 2004-07-12 JP JP2006520262A patent/JP2007524077A/ja not_active Ceased
- 2004-07-12 US US10/889,538 patent/US7488604B2/en not_active Expired - Fee Related
-
2009
- 2009-02-09 US US12/368,055 patent/US20090301232A1/en not_active Abandoned
Patent Citations (7)
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US5460782A (en) * | 1994-07-18 | 1995-10-24 | Safe-Tec Clinical Products, Inc. | Automatic filling micropipette with dispensing means |
US6001309A (en) * | 1996-05-17 | 1999-12-14 | Incyte Pharmaceuticals, Inc. | Jet droplet device |
JP2000513266A (ja) * | 1996-05-17 | 2000-10-10 | インサイト・ファーマスーティカルズ・インコーポレイテッド | 液体粒子噴射装置及びその利用方法 |
JPH10311840A (ja) * | 1997-05-13 | 1998-11-24 | Horiba Ltd | 液体吸引装置 |
US6309891B1 (en) * | 1998-09-09 | 2001-10-30 | Incyte Genomics, Inc. | Capillary printing systems |
JP2003519360A (ja) * | 1998-09-09 | 2003-06-17 | インサイト ジェノミックス インコーポレイテッド | 毛細管印刷システム |
US20030086828A1 (en) * | 2001-11-05 | 2003-05-08 | Industrial Technology Research Institute | Micro-dispenser for biochemical analysis |
Also Published As
Publication number | Publication date |
---|---|
US20050112776A1 (en) | 2005-05-26 |
US7488604B2 (en) | 2009-02-10 |
WO2005007289A2 (en) | 2005-01-27 |
WO2005007289A3 (en) | 2005-10-06 |
EP1654067A2 (en) | 2006-05-10 |
EP1654067A4 (en) | 2008-01-02 |
US20090301232A1 (en) | 2009-12-10 |
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