JP2007519743A5 - - Google Patents
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- Publication number
- JP2007519743A5 JP2007519743A5 JP2006551509A JP2006551509A JP2007519743A5 JP 2007519743 A5 JP2007519743 A5 JP 2007519743A5 JP 2006551509 A JP2006551509 A JP 2006551509A JP 2006551509 A JP2006551509 A JP 2006551509A JP 2007519743 A5 JP2007519743 A5 JP 2007519743A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- alkyl
- aryl
- substituted
- composition according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 150000001875 compounds Chemical class 0.000 claims 7
- 125000003118 aryl group Chemical group 0.000 claims 6
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 claims 6
- 125000001475 halogen functional group Chemical group 0.000 claims 6
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical group [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims 5
- 125000000217 alkyl group Chemical group 0.000 claims 5
- 229910052799 carbon Inorganic materials 0.000 claims 5
- -1 cyano, nitro, amino Chemical group 0.000 claims 5
- 125000000392 cycloalkenyl group Chemical group 0.000 claims 5
- 125000000623 heterocyclic group Chemical group 0.000 claims 4
- 125000004366 heterocycloalkenyl group Chemical group 0.000 claims 4
- 125000001831 (C6-C10) heteroaryl group Chemical group 0.000 claims 3
- 125000003710 aryl alkyl group Chemical group 0.000 claims 3
- 125000000753 cycloalkyl group Chemical group 0.000 claims 3
- 229910052760 oxygen Inorganic materials 0.000 claims 3
- 125000001424 substituent group Chemical group 0.000 claims 3
- 229910052717 sulfur Inorganic materials 0.000 claims 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims 2
- 229910052739 hydrogen Inorganic materials 0.000 claims 2
- 125000004356 hydroxy functional group Chemical group O* 0.000 claims 2
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 claims 2
- 230000003287 optical effect Effects 0.000 claims 2
- 235000001508 sulfur Nutrition 0.000 claims 2
- 125000000027 (C1-C10) alkoxy group Chemical group 0.000 claims 1
- 125000004890 (C1-C6) alkylamino group Chemical group 0.000 claims 1
- 125000006619 (C1-C6) dialkylamino group Chemical group 0.000 claims 1
- 125000004737 (C1-C6) haloalkoxy group Chemical group 0.000 claims 1
- 125000000171 (C1-C6) haloalkyl group Chemical group 0.000 claims 1
- 125000006710 (C2-C12) alkenyl group Chemical group 0.000 claims 1
- 125000006711 (C2-C12) alkynyl group Chemical group 0.000 claims 1
- FUZYTVDVLBBXDL-UHFFFAOYSA-N 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide Chemical compound N1C2=CC=C(Cl)C=C2C2=C1C(C(=O)N)CCC2 FUZYTVDVLBBXDL-UHFFFAOYSA-N 0.000 claims 1
- 125000001313 C5-C10 heteroaryl group Chemical group 0.000 claims 1
- 241000243251 Hydra Species 0.000 claims 1
- MUBZPKHOEPUJKR-UHFFFAOYSA-N Oxalic acid Chemical compound OC(=O)C(O)=O MUBZPKHOEPUJKR-UHFFFAOYSA-N 0.000 claims 1
- 229910019142 PO4 Inorganic materials 0.000 claims 1
- 102000011990 Sirtuin Human genes 0.000 claims 1
- 108050002485 Sirtuin Proteins 0.000 claims 1
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 claims 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 claims 1
- 125000002252 acyl group Chemical group 0.000 claims 1
- 125000003545 alkoxy group Chemical group 0.000 claims 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 claims 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 claims 1
- 125000004475 heteroaralkyl group Chemical group 0.000 claims 1
- 125000004446 heteroarylalkyl group Chemical group 0.000 claims 1
- 239000001257 hydrogen Substances 0.000 claims 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 claims 1
- 230000001404 mediated effect Effects 0.000 claims 1
- 229910052757 nitrogen Inorganic materials 0.000 claims 1
- 125000004043 oxo group Chemical group O=* 0.000 claims 1
- 239000001301 oxygen Substances 0.000 claims 1
- GJVFBWCTGUSGDD-UHFFFAOYSA-L pentamethonium bromide Chemical compound [Br-].[Br-].C[N+](C)(C)CCCCC[N+](C)(C)C GJVFBWCTGUSGDD-UHFFFAOYSA-L 0.000 claims 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 claims 1
- 239000010452 phosphate Substances 0.000 claims 1
- PXQLVRUNWNTZOS-UHFFFAOYSA-N sulfanyl Chemical class [SH] PXQLVRUNWNTZOS-UHFFFAOYSA-N 0.000 claims 1
- 239000011593 sulfur Substances 0.000 claims 1
- 229910021653 sulphate ion Inorganic materials 0.000 claims 1
- GBXQPDCOMJJCMJ-UHFFFAOYSA-M trimethyl-[6-(trimethylazaniumyl)hexyl]azanium;bromide Chemical compound [Br-].C[N+](C)(C)CCCCCC[N+](C)(C)C GBXQPDCOMJJCMJ-UHFFFAOYSA-M 0.000 claims 1
- 0 *[C@](C1)C1N(C1C(*)CCCC11)c2c1cc(*)cc2 Chemical compound *[C@](C1)C1N(C1C(*)CCCC11)c2c1cc(*)cc2 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US54042904P | 2004-01-29 | 2004-01-29 | |
| US56048404P | 2004-04-07 | 2004-04-07 | |
| PCT/US2005/002755 WO2005072408A2 (en) | 2004-01-29 | 2005-01-31 | Treating a viral disorder |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007519743A JP2007519743A (ja) | 2007-07-19 |
| JP2007519743A5 true JP2007519743A5 (enExample) | 2008-03-06 |
Family
ID=34830506
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006551509A Withdrawn JP2007519743A (ja) | 2004-01-29 | 2005-01-31 | ウイルス障害の処置 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20050256181A1 (enExample) |
| EP (1) | EP1734950A4 (enExample) |
| JP (1) | JP2007519743A (enExample) |
| AU (1) | AU2005208934A1 (enExample) |
| CA (1) | CA2553814A1 (enExample) |
| WO (1) | WO2005072408A2 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060074124A1 (en) * | 2003-09-12 | 2006-04-06 | Andrew Napper | Methods of treating a disorder |
| JP2008514611A (ja) * | 2004-09-23 | 2008-05-08 | ワイス | Ｃ型肝炎ウイルスによる感染を処置するためのカルバゾールおよびシクロペンタインドールの誘導体 |
| WO2007047604A2 (en) * | 2005-10-18 | 2007-04-26 | Elixir Pharmaceuticals, Inc. | Sirt1 inhibition |
| WO2008019825A1 (en) * | 2006-08-14 | 2008-02-21 | Santhera Pharmaceuticals (Schweiz) Ag | Use of tricyclic indole derivatives for the treatment of muscular diseases |
| WO2008156656A2 (en) * | 2007-06-13 | 2008-12-24 | State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University | Method for making biaryl compounds, compounds made by the method, and method for their use |
| US8568756B2 (en) * | 2008-06-02 | 2013-10-29 | The Trustees Of Princeton University | Inhibition of quorum sensing-mediated processes in bacteria |
| MX2012004118A (es) * | 2009-10-09 | 2012-05-08 | Nestec Sa | Metodos para prevenir o tratar sarcopenia y atrofia muscular en animales. |
| AR088377A1 (es) * | 2011-10-20 | 2014-05-28 | Siena Biotech Spa | Proceso para la preparacion de 6-cloro-2,3,4,9-tetrahidro-1h-carbazol-1-carboxamida y compuestos intermedios de esta |
| WO2017120409A1 (en) | 2016-01-06 | 2017-07-13 | Auspex Pharmaceuticals, Inc. | Tetrahydrocarbazole inhibitors of sirt1 receptors |
| US20230255933A1 (en) * | 2020-07-06 | 2023-08-17 | Crescenta Biosciences | Antiviral use of fabp4 modulating compounds |
| US12138243B2 (en) | 2021-12-31 | 2024-11-12 | Crescenta Biosciences | Antiviral use of FABP4 modulating compounds |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1011670A4 (en) * | 1997-08-28 | 2004-10-27 | Lilly Co Eli | PROCESS FOR TREATING NON-RHUMATOID POLYARTHRITIS |
| EP1043991A4 (en) * | 1997-11-14 | 2005-02-02 | Lilly Co Eli | TREATMENT OF ALZHEIMER DISEASE |
| US20040005574A1 (en) * | 2002-07-08 | 2004-01-08 | Leonard Guarente | SIR2 activity |
| US7351542B2 (en) * | 2002-05-20 | 2008-04-01 | The Regents Of The University Of California | Methods of modulating tubulin deacetylase activity |
-
2005
- 2005-01-31 US US11/047,757 patent/US20050256181A1/en not_active Abandoned
- 2005-01-31 JP JP2006551509A patent/JP2007519743A/ja not_active Withdrawn
- 2005-01-31 AU AU2005208934A patent/AU2005208934A1/en not_active Abandoned
- 2005-01-31 CA CA002553814A patent/CA2553814A1/en not_active Abandoned
- 2005-01-31 WO PCT/US2005/002755 patent/WO2005072408A2/en not_active Ceased
- 2005-01-31 EP EP05712266A patent/EP1734950A4/en not_active Withdrawn
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