JP2007511577A5 - - Google Patents
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- Publication number
- JP2007511577A5 JP2007511577A5 JP2006540363A JP2006540363A JP2007511577A5 JP 2007511577 A5 JP2007511577 A5 JP 2007511577A5 JP 2006540363 A JP2006540363 A JP 2006540363A JP 2006540363 A JP2006540363 A JP 2006540363A JP 2007511577 A5 JP2007511577 A5 JP 2007511577A5
- Authority
- JP
- Japan
- Prior art keywords
- chlorophenyl
- trimethyl
- salt
- morpholinol
- solvate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000003839 salts Chemical class 0.000 claims 12
- 239000008194 pharmaceutical composition Substances 0.000 claims 8
- 239000012453 solvate Substances 0.000 claims 8
- RCOBKSKAZMVBHT-TVQRCGJNSA-N radafaxine Chemical compound C[C@@H]1NC(C)(C)CO[C@@]1(O)C1=CC=CC(Cl)=C1 RCOBKSKAZMVBHT-TVQRCGJNSA-N 0.000 claims 7
- ORXTVTDGPVINDN-BTJVGWIPSA-N (2s,3s)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol;hydrochloride Chemical group Cl.C[C@@H]1NC(C)(C)CO[C@@]1(O)C1=CC=CC(Cl)=C1 ORXTVTDGPVINDN-BTJVGWIPSA-N 0.000 claims 4
- 239000003814 drug Substances 0.000 claims 4
- 208000005793 Restless legs syndrome Diseases 0.000 claims 3
- 241000124008 Mammalia Species 0.000 claims 2
- 239000003937 drug carrier Substances 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 208000023515 periodic limb movement disease Diseases 0.000 claims 2
- 125000004179 3-chlorophenyl group Chemical group [H]C1=C([H])C(*)=C([H])C(Cl)=C1[H] 0.000 claims 1
- OURXRFYZEOUCRM-UHFFFAOYSA-N 4-hydroxymorpholine Chemical compound ON1CCOCC1 OURXRFYZEOUCRM-UHFFFAOYSA-N 0.000 claims 1
- 208000008705 Nocturnal Myoclonus Syndrome Diseases 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0327195.4A GB0327195D0 (en) | 2003-11-21 | 2003-11-21 | Novel use |
| PCT/EP2004/013248 WO2005053700A1 (en) | 2003-11-21 | 2004-11-19 | Use of (2s,3s)2-(3-chlorophenyl)-3,5,5-trimethyl-2-morpholinol |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007511577A JP2007511577A (ja) | 2007-05-10 |
| JP2007511577A5 true JP2007511577A5 (https=) | 2007-12-13 |
Family
ID=29764268
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006540363A Pending JP2007511577A (ja) | 2003-11-21 | 2004-11-19 | （２ｓ，３ｓ）−２−（３−クロロフェニル）−３，５，５−トリメチル−２−モルホリノールの使用 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20070142378A1 (https=) |
| EP (1) | EP1684765A1 (https=) |
| JP (1) | JP2007511577A (https=) |
| AR (1) | AR046641A1 (https=) |
| GB (1) | GB0327195D0 (https=) |
| TW (1) | TW200529858A (https=) |
| WO (1) | WO2005053700A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0425445D0 (en) * | 2004-11-18 | 2004-12-22 | Smithkline Beecham Corp | Novel compositions |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL193622B1 (pl) * | 1998-01-21 | 2007-02-28 | Glaxo Group Ltd | Farmaceutycznie czynny morfolinol, zawierająca gokompozycja oraz jego zastosowanie |
| US7098206B2 (en) * | 1998-01-21 | 2006-08-29 | Smithkline Beecham Corporation | Pharmaceutically active morpholinol |
| US6337328B1 (en) * | 1999-03-01 | 2002-01-08 | Sepracor, Inc. | Bupropion metabolites and methods of use |
| US6342496B1 (en) * | 1999-03-01 | 2002-01-29 | Sepracor Inc. | Bupropion metabolites and methods of use |
| EP1336406A1 (en) * | 2002-02-14 | 2003-08-20 | Solvay Pharmaceuticals B.V. | Partial dopamine-D2 receptor agonist plus serotonin and/or noradrenaline inhibitory activity |
-
2003
- 2003-11-21 GB GBGB0327195.4A patent/GB0327195D0/en not_active Ceased
-
2004
- 2004-11-19 WO PCT/EP2004/013248 patent/WO2005053700A1/en not_active Ceased
- 2004-11-19 JP JP2006540363A patent/JP2007511577A/ja active Pending
- 2004-11-19 TW TW093135507A patent/TW200529858A/zh unknown
- 2004-11-19 AR ARP040104268A patent/AR046641A1/es unknown
- 2004-11-19 EP EP04803222A patent/EP1684765A1/en not_active Withdrawn
- 2004-11-19 US US10/595,885 patent/US20070142378A1/en not_active Abandoned
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