JP2007510515A - 非経口薬物送達および診断サンプリング用構造体およびデバイス - Google Patents
非経口薬物送達および診断サンプリング用構造体およびデバイス Download PDFInfo
- Publication number
- JP2007510515A JP2007510515A JP2006539743A JP2006539743A JP2007510515A JP 2007510515 A JP2007510515 A JP 2007510515A JP 2006539743 A JP2006539743 A JP 2006539743A JP 2006539743 A JP2006539743 A JP 2006539743A JP 2007510515 A JP2007510515 A JP 2007510515A
- Authority
- JP
- Japan
- Prior art keywords
- tissue
- rigid structure
- rigid
- titanium
- ingrowth
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000012377 drug delivery Methods 0.000 title claims description 13
- 238000005070 sampling Methods 0.000 title abstract description 10
- 230000001737 promoting effect Effects 0.000 claims abstract description 51
- 238000000034 method Methods 0.000 claims abstract description 40
- 238000004519 manufacturing process Methods 0.000 claims abstract description 16
- 239000000463 material Substances 0.000 claims description 62
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 claims description 17
- 239000010936 titanium Substances 0.000 claims description 17
- 229910052719 titanium Inorganic materials 0.000 claims description 17
- 239000000560 biocompatible material Substances 0.000 claims description 16
- 239000012530 fluid Substances 0.000 claims description 15
- 238000000151 deposition Methods 0.000 claims description 12
- 210000004962 mammalian cell Anatomy 0.000 claims description 6
- 229910001069 Ti alloy Inorganic materials 0.000 claims description 5
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 claims description 5
- OGIDPMRJRNCKJF-UHFFFAOYSA-N titanium oxide Inorganic materials [Ti]=O OGIDPMRJRNCKJF-UHFFFAOYSA-N 0.000 claims description 5
- 238000005459 micromachining Methods 0.000 claims description 4
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- 238000004070 electrodeposition Methods 0.000 claims description 3
- 238000003486 chemical etching Methods 0.000 claims description 2
- 238000005229 chemical vapour deposition Methods 0.000 claims description 2
- 238000010329 laser etching Methods 0.000 claims description 2
- 238000005240 physical vapour deposition Methods 0.000 claims description 2
- 150000003608 titanium Chemical class 0.000 claims 3
- 239000000470 constituent Substances 0.000 claims 1
- 238000000708 deep reactive-ion etching Methods 0.000 claims 1
- 230000008020 evaporation Effects 0.000 claims 1
- 238000001704 evaporation Methods 0.000 claims 1
- 239000013060 biological fluid Substances 0.000 abstract description 8
- 239000003814 drug Substances 0.000 abstract description 5
- 229940124597 therapeutic agent Drugs 0.000 abstract description 2
- 230000001225 therapeutic effect Effects 0.000 abstract description 2
- 210000003850 cellular structure Anatomy 0.000 abstract 1
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- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 2
- 229920005597 polymer membrane Polymers 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
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- 241000894006 Bacteria Species 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 108010043121 Green Fluorescent Proteins Proteins 0.000 description 1
- 102000004144 Green Fluorescent Proteins Human genes 0.000 description 1
- 229910000846 In alloy Inorganic materials 0.000 description 1
- 102000004877 Insulin Human genes 0.000 description 1
- 108090001061 Insulin Proteins 0.000 description 1
- 229910052581 Si3N4 Inorganic materials 0.000 description 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 1
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 1
- RLNMYVSYJAGLAD-UHFFFAOYSA-N [In].[Pt] Chemical compound [In].[Pt] RLNMYVSYJAGLAD-UHFFFAOYSA-N 0.000 description 1
- 210000000683 abdominal cavity Anatomy 0.000 description 1
- 229910045601 alloy Inorganic materials 0.000 description 1
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- 239000002260 anti-inflammatory agent Substances 0.000 description 1
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- 230000003385 bacteriostatic effect Effects 0.000 description 1
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- 239000003012 bilayer membrane Substances 0.000 description 1
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- 239000000919 ceramic Substances 0.000 description 1
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- 239000005090 green fluorescent protein Substances 0.000 description 1
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- 229910052738 indium Inorganic materials 0.000 description 1
- APFVFJFRJDLVQX-UHFFFAOYSA-N indium atom Chemical compound [In] APFVFJFRJDLVQX-UHFFFAOYSA-N 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 229940125396 insulin Drugs 0.000 description 1
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- 229910052751 metal Inorganic materials 0.000 description 1
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- 229920002120 photoresistant polymer Polymers 0.000 description 1
- 239000006187 pill Substances 0.000 description 1
- 229910052697 platinum Inorganic materials 0.000 description 1
- 208000003580 polydactyly Diseases 0.000 description 1
- 229920006254 polymer film Polymers 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- 230000037390 scarring Effects 0.000 description 1
- HBMJWWWQQXIZIP-UHFFFAOYSA-N silicon carbide Chemical compound [Si+]#[C-] HBMJWWWQQXIZIP-UHFFFAOYSA-N 0.000 description 1
- 229910010271 silicon carbide Inorganic materials 0.000 description 1
- HQVNEWCFYHHQES-UHFFFAOYSA-N silicon nitride Chemical compound N12[Si]34N5[Si]62N3[Si]51N64 HQVNEWCFYHHQES-UHFFFAOYSA-N 0.000 description 1
- 229910052814 silicon oxide Inorganic materials 0.000 description 1
- 210000004872 soft tissue Anatomy 0.000 description 1
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- 238000013271 transdermal drug delivery Methods 0.000 description 1
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- 238000000108 ultra-filtration Methods 0.000 description 1
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Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/0077—Special surfaces of prostheses, e.g. for improving ingrowth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
- A61F2250/0067—Means for introducing or releasing pharmaceutical products into the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0043—Catheters; Hollow probes characterised by structural features
- A61M2025/006—Catheters; Hollow probes characterised by structural features having a special surface topography or special surface properties, e.g. roughened or knurled surface
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
- A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Transplantation (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Vascular Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Cardiology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Prostheses (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Media Introduction/Drainage Providing Device (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US51906003P | 2003-11-10 | 2003-11-10 | |
| PCT/US2004/037338 WO2005046446A2 (en) | 2003-11-10 | 2004-11-08 | Structures and devices for parenteral drug delivery and diagnostic sampling |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007510515A true JP2007510515A (ja) | 2007-04-26 |
| JP2007510515A5 JP2007510515A5 (enExample) | 2010-12-24 |
Family
ID=34590345
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006539743A Pending JP2007510515A (ja) | 2003-11-10 | 2004-11-08 | 非経口薬物送達および診断サンプリング用構造体およびデバイス |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20050203637A1 (enExample) |
| EP (1) | EP1691662A4 (enExample) |
| JP (1) | JP2007510515A (enExample) |
| AU (1) | AU2004289288B2 (enExample) |
| CA (1) | CA2548307A1 (enExample) |
| WO (1) | WO2005046446A2 (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5241714B2 (ja) | 2006-07-07 | 2013-07-17 | プロテウス デジタル ヘルス， インコーポレイテッド | スマートな非経口送達システム |
| WO2009036306A1 (en) | 2007-09-14 | 2009-03-19 | Corventis, Inc. | Adherent cardiac monitor with advanced sensing capabilities |
| US8374688B2 (en) | 2007-09-14 | 2013-02-12 | Corventis, Inc. | System and methods for wireless body fluid monitoring |
| US8684925B2 (en) | 2007-09-14 | 2014-04-01 | Corventis, Inc. | Injectable device for physiological monitoring |
| EP2200512A1 (en) | 2007-09-14 | 2010-06-30 | Corventis, Inc. | Adherent device for respiratory monitoring and sleep disordered breathing |
| WO2009036348A1 (en) | 2007-09-14 | 2009-03-19 | Corventis, Inc. | Medical device automatic start-up upon contact to patient tissue |
| WO2009036316A1 (en) | 2007-09-14 | 2009-03-19 | Corventis, Inc. | Energy management, tracking and security for adherent patient monitor |
| EP2194847A1 (en) | 2007-09-14 | 2010-06-16 | Corventis, Inc. | Adherent device with multiple physiological sensors |
| EP2211974A4 (en) | 2007-10-25 | 2013-02-27 | Proteus Digital Health Inc | INFORMATION SYSTEM FOR LIQUID FLOW CHANNEL |
| WO2009067463A1 (en) | 2007-11-19 | 2009-05-28 | Proteus Biomedical, Inc. | Body-associated fluid transport structure evaluation devices |
| AU2014253554B2 (en) * | 2007-11-19 | 2016-04-28 | Massachusetts Institute Of Technology | Adhesive articles |
| EP2214590B1 (en) * | 2007-11-19 | 2016-08-31 | Massachusetts Institute of Technology | Adhesive articles |
| JP5405500B2 (ja) | 2008-03-12 | 2014-02-05 | コーヴェンティス，インク． | 心調律に基づく心代償不全予測 |
| US8412317B2 (en) | 2008-04-18 | 2013-04-02 | Corventis, Inc. | Method and apparatus to measure bioelectric impedance of patient tissue |
| US20090292194A1 (en) * | 2008-05-23 | 2009-11-26 | Corventis, Inc. | Chiropractic Care Management Systems and Methods |
| WO2011050283A2 (en) | 2009-10-22 | 2011-04-28 | Corventis, Inc. | Remote detection and monitoring of functional chronotropic incompetence |
| US9451897B2 (en) | 2009-12-14 | 2016-09-27 | Medtronic Monitoring, Inc. | Body adherent patch with electronics for physiologic monitoring |
| MY169700A (en) | 2010-02-01 | 2019-05-13 | Proteus Digital Health Inc | Data gathering system |
| AU2011210648B2 (en) | 2010-02-01 | 2014-10-16 | Otsuka Pharmaceutical Co., Ltd. | Data gathering system |
| US8965498B2 (en) | 2010-04-05 | 2015-02-24 | Corventis, Inc. | Method and apparatus for personalized physiologic parameters |
| CN111166532B (zh) * | 2019-12-30 | 2022-03-01 | 武汉联影智融医疗科技有限公司 | 人工关节及其制备方法 |
| CA3229128A1 (en) * | 2021-08-13 | 2023-02-16 | Mott Corporation | Drug delivery assembly for extended drug delivery and tunability |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH02152470A (ja) * | 1988-11-22 | 1990-06-12 | Baxter Internatl Inc | 柔組織に移植するための物質移動装置 |
| US5207709A (en) * | 1991-11-13 | 1993-05-04 | Picha George J | Implant with textured surface |
| JP2003503134A (ja) * | 1999-07-01 | 2003-01-28 | メドトロニック ミニメド インコーポレイテッド | 再使用可能な分析物センササイト |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4378016A (en) * | 1981-07-15 | 1983-03-29 | Biotek, Inc. | Artificial endocrine gland containing hormone-producing cells |
| US4490137A (en) * | 1982-09-30 | 1984-12-25 | Moukheibir Nabil W | Surgically implantable peritoneal dialysis apparatus |
| EP0417089A1 (en) * | 1988-05-02 | 1991-03-20 | SVENSON, Jan, Axel | Implant passageway |
| US5109850A (en) * | 1990-02-09 | 1992-05-05 | Massachusetts Institute Of Technology | Automatic blood monitoring for medication delivery method and apparatus |
| US5314471A (en) * | 1991-07-24 | 1994-05-24 | Baxter International Inc. | Tissue inplant systems and methods for sustaining viable high cell densities within a host |
| US5090954A (en) * | 1991-05-17 | 1992-02-25 | Geary Gregory L | Subcutaneous access device for peritoneal dialysis |
| US5211833A (en) * | 1991-07-24 | 1993-05-18 | Queen's University At Kingston | Method for coating implants and surgical devices made of titanium and titanium alloys |
| NO924697D0 (no) * | 1992-12-04 | 1992-12-04 | Jan Erik Ellingsen | Kirurgisk implantat og en fremgangsmaate for behandling avkirurgisk implantat |
| US6042561A (en) * | 1997-10-22 | 2000-03-28 | Ash Medical Systems, Inc. | Non-intravascular infusion access device |
| WO2000074763A2 (en) * | 1999-06-04 | 2000-12-14 | Georgia Tech Research Corporation | Devices and methods for enhanced microneedle penetration of biological barriers |
| US6520997B1 (en) | 1999-12-08 | 2003-02-18 | Baxter International Inc. | Porous three dimensional structure |
| DE10053763C2 (de) * | 2000-10-30 | 2002-10-17 | Pilz Gmbh & Co | Feldbussystem zum Steuern von sicherheitskritischen Prozessen sowie Busanschaltmodul zur Verwendung in einem solchen Feldbussystem |
| US6620332B2 (en) * | 2001-01-25 | 2003-09-16 | Tecomet, Inc. | Method for making a mesh-and-plate surgical implant |
| US20040106951A1 (en) | 2002-11-22 | 2004-06-03 | Edman Carl Frederick | Use of electric fields to minimize rejection of implanted devices and materials |
-
2004
- 2004-11-08 EP EP04810589A patent/EP1691662A4/en not_active Withdrawn
- 2004-11-08 JP JP2006539743A patent/JP2007510515A/ja active Pending
- 2004-11-08 AU AU2004289288A patent/AU2004289288B2/en not_active Ceased
- 2004-11-08 WO PCT/US2004/037338 patent/WO2005046446A2/en not_active Ceased
- 2004-11-08 US US10/984,681 patent/US20050203637A1/en not_active Abandoned
- 2004-11-08 CA CA002548307A patent/CA2548307A1/en not_active Abandoned
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH02152470A (ja) * | 1988-11-22 | 1990-06-12 | Baxter Internatl Inc | 柔組織に移植するための物質移動装置 |
| US5207709A (en) * | 1991-11-13 | 1993-05-04 | Picha George J | Implant with textured surface |
| JP2003503134A (ja) * | 1999-07-01 | 2003-01-28 | メドトロニック ミニメド インコーポレイテッド | 再使用可能な分析物センササイト |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2004289288B2 (en) | 2011-07-28 |
| US20050203637A1 (en) | 2005-09-15 |
| WO2005046446A3 (en) | 2006-08-31 |
| EP1691662A2 (en) | 2006-08-23 |
| EP1691662A4 (en) | 2007-05-02 |
| AU2004289288A1 (en) | 2005-05-26 |
| WO2005046446A2 (en) | 2005-05-26 |
| CA2548307A1 (en) | 2005-05-26 |
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