JP2007509941A - ラクトース無水物を用いる吸入医薬製剤およびその投与方法 - Google Patents

ラクトース無水物を用いる吸入医薬製剤およびその投与方法 Download PDF

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Publication number
JP2007509941A
JP2007509941A JP2006538128A JP2006538128A JP2007509941A JP 2007509941 A JP2007509941 A JP 2007509941A JP 2006538128 A JP2006538128 A JP 2006538128A JP 2006538128 A JP2006538128 A JP 2006538128A JP 2007509941 A JP2007509941 A JP 2007509941A
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JP
Japan
Prior art keywords
lactose
inhaler
medicament
pharmaceutical formulation
formulation
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Pending
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JP2006538128A
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English (en)
Japanese (ja)
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JP2007509941A5 (https=
Inventor
ドーソン，ミシェル，エル．
ロシュ，トレヴォア，シー．
ウィッテイカー，マーク
チダバエンズィ，オーウェン，チゾーラ
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Glaxo Group Ltd
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Glaxo Group Ltd
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Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of JP2007509941A publication Critical patent/JP2007509941A/ja
Publication of JP2007509941A5 publication Critical patent/JP2007509941A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Otolaryngology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2006538128A 2003-10-28 2004-10-22 ラクトース無水物を用いる吸入医薬製剤およびその投与方法 Pending JP2007509941A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51507703P 2003-10-28 2003-10-28
PCT/US2004/035129 WO2005044187A2 (en) 2003-10-28 2004-10-22 Inhalable pharmaceutical formulations employing lactose anhydrate and methods of administering the same

Publications (2)

Publication Number Publication Date
JP2007509941A true JP2007509941A (ja) 2007-04-19
JP2007509941A5 JP2007509941A5 (https=) 2007-07-12

Family

ID=34572801

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006538128A Pending JP2007509941A (ja) 2003-10-28 2004-10-22 ラクトース無水物を用いる吸入医薬製剤およびその投与方法

Country Status (6)

Country Link
US (1) US20070053843A1 (https=)
EP (1) EP1686960A4 (https=)
JP (1) JP2007509941A (https=)
CA (1) CA2543482A1 (https=)
IL (1) IL175032A0 (https=)
WO (1) WO2005044187A2 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015046489A1 (ja) 2013-09-30 2015-04-02 第一三共株式会社 スプレードライ法を用いたＤ－マンニトールα型結晶の選択的製造方法
JP2016519123A (ja) * 2013-04-29 2016-06-30 サノフィ・ソシエテ・アノニム 吸入可能な医薬組成物およびそれらを収容した吸入器デバイス

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GB0501956D0 (en) * 2005-01-31 2005-03-09 Arrow Internat Nebulizer formulation
GB0520794D0 (en) * 2005-10-12 2005-11-23 Innovata Biomed Ltd Inhaler
CN101744792B (zh) * 2008-12-17 2013-04-17 张凯 氟替卡松丙酸酯和沙美特罗昔萘酸酯复方干粉吸入剂及其制备工艺
US9925282B2 (en) 2009-01-29 2018-03-27 The General Hospital Corporation Cromolyn derivatives and related methods of imaging and treatment
US8834931B2 (en) 2009-12-25 2014-09-16 Mahmut Bilgic Dry powder formulation containing tiotropium for inhalation
TR200909788A2 (tr) * 2009-12-25 2011-07-21 Bi̇lgi̇ç Mahmut Tiotropyum içeren inhalasyona uygun kuru toz formülasyonu
TR201000685A2 (tr) * 2010-01-29 2011-08-22 Bi̇lgi̇ç Mahmut Salmeterol ve flutikazon içeren farmasötik preparatlar.
WO2011093815A2 (en) * 2010-01-29 2011-08-04 Mahmut Bilgic Pharmaceutical compositions comprising formoterol and mometasone
WO2014007772A2 (en) 2012-07-05 2014-01-09 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Inhalation compositions comprising glucose anhydrous
WO2014007771A2 (en) 2012-07-05 2014-01-09 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Inhalation compositions comprising muscarinic receptor antagonist
WO2014007770A2 (en) * 2012-07-05 2014-01-09 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Inhalation compositions comprising corticosteroid and sorbitol
AU2014340182B2 (en) * 2013-10-22 2019-05-23 The General Hospital Corporation Cromolyn derivatives and related methods of imaging and treatment
WO2016037166A1 (en) * 2014-09-07 2016-03-10 Yu Zhang Novel anti-oxidant compositions and methods of delivery
WO2016067252A1 (en) 2014-10-31 2016-05-06 Glaxosmithkline Intellectual Property Development Limited Powder formulation
CA3033079A1 (en) 2016-08-31 2018-03-08 The General Hospital Corporation Macrophages/microglia in neuro-inflammation associated with neurodegenerative diseases
WO2020123449A1 (en) 2018-12-10 2020-06-18 The General Hospital Corporation Cromolyn esters and uses thereof
EP4132507A4 (en) 2020-04-06 2024-05-15 The General Hospital Corporation Methods of treatment of coronavirus-induced inflammation conditions

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998050015A1 (en) * 1997-05-07 1998-11-12 Pharlyse, Societe Anonyme Dry powder inhaler excipient, process for its preparation and pharmaceutical compositions containing it
JP2000510100A (ja) * 1996-03-23 2000-08-08 ウエスト、ファルマシューティカル、サービシズ、ドラッグ、デリバリー、アンド、クリニカル、リサーチ、センター、リミテッド 医薬物質の肺送達のためのポリサッカライド微小球

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US4778054A (en) * 1982-10-08 1988-10-18 Glaxo Group Limited Pack for administering medicaments to patients
DE3682457D1 (de) * 1985-07-30 1991-12-19 Glaxo Group Ltd Geraet zur verabreichung von medikamenten an patienten.
SK280968B6 (sk) * 1990-03-02 2000-10-09 Glaxo Group Limited Balenie medikamentu na použite v inhalačnom prístroji
US6536427B2 (en) * 1990-03-02 2003-03-25 Glaxo Group Limited Inhalation device
GB9004781D0 (en) * 1990-03-02 1990-04-25 Glaxo Group Ltd Device
PE44995A1 (es) * 1994-01-27 1995-12-18 Schering Corp Furoato de mometasona para el tratamiento de las enfermedades pulmonares y de las vias respiratorias
GB9404945D0 (en) * 1994-03-15 1994-04-27 Glaxo Group Ltd Pharmaceutical composition
KR19980703850A (ko) * 1995-04-14 1998-12-05 그레이엄브레레톤 베클로메타손 디프로피오네이트용 계량 흡입기
MX9707862A (es) * 1995-04-14 1997-11-29 Glaxo Wellcome Inc Inhalador de dosis medida para el propionato de fluticasona.
AP791A (en) * 1995-04-14 1999-12-17 Glaxo Wellcome Inc Metered dose inhaler for albuterol.
US6258341B1 (en) * 1995-04-14 2001-07-10 Inhale Therapeutic Systems, Inc. Stable glassy state powder formulations
MX9707864A (es) * 1995-04-14 1997-11-29 Glaxo Wellcome Inc Inhalador de dosis medida por salmeterol.
GB9626960D0 (en) * 1996-12-27 1997-02-12 Glaxo Group Ltd Valve for aerosol container
GB9700226D0 (en) * 1997-01-08 1997-02-26 Glaxo Group Ltd Inhalation device
US6495167B2 (en) * 1997-03-20 2002-12-17 Schering Corporation Preparation of powder agglomerates
DK0969816T3 (da) * 1997-03-20 2005-03-14 Schering Corp Fremstilling af pulveragglomerater
TW533865U (en) * 1997-06-10 2003-05-21 Glaxo Group Ltd Dispenser for dispensing medicament and actuation indicating device
GB2329939A (en) * 1997-06-26 1999-04-07 Glaxo Group Ltd Self-lubricating valve stem for aerosol containers
AU756852B2 (en) * 1998-11-13 2003-01-23 Jagotec Ag Dry powder for inhalation
US6390291B1 (en) * 1998-12-18 2002-05-21 Smithkline Beecham Corporation Method and package for storing a pressurized container containing a drug
TR200401462T4 (tr) * 2000-02-17 2004-08-23 Teva Pharmaceutical Industries Ltd. Torsemid modifikasyonu II' yi içeren dengeli bir farmasötik formülasyonu

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000510100A (ja) * 1996-03-23 2000-08-08 ウエスト、ファルマシューティカル、サービシズ、ドラッグ、デリバリー、アンド、クリニカル、リサーチ、センター、リミテッド 医薬物質の肺送達のためのポリサッカライド微小球
WO1998050015A1 (en) * 1997-05-07 1998-11-12 Pharlyse, Societe Anonyme Dry powder inhaler excipient, process for its preparation and pharmaceutical compositions containing it

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016519123A (ja) * 2013-04-29 2016-06-30 サノフィ・ソシエテ・アノニム 吸入可能な医薬組成物およびそれらを収容した吸入器デバイス
WO2015046489A1 (ja) 2013-09-30 2015-04-02 第一三共株式会社 スプレードライ法を用いたＤ－マンニトールα型結晶の選択的製造方法

Also Published As

Publication number Publication date
EP1686960A2 (en) 2006-08-09
CA2543482A1 (en) 2005-05-19
US20070053843A1 (en) 2007-03-08
WO2005044187A2 (en) 2005-05-19
WO2005044187A3 (en) 2006-03-23
EP1686960A4 (en) 2007-03-07
IL175032A0 (en) 2008-04-13

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