JP2007505131A - Ｗｉｓｐアンタゴニストの使用方法 - Google Patents

Ｗｉｓｐアンタゴニストの使用方法 Download PDF

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Publication number
JP2007505131A
JP2007505131A JP2006526300A JP2006526300A JP2007505131A JP 2007505131 A JP2007505131 A JP 2007505131A JP 2006526300 A JP2006526300 A JP 2006526300A JP 2006526300 A JP2006526300 A JP 2006526300A JP 2007505131 A JP2007505131 A JP 2007505131A
Authority
JP
Japan
Prior art keywords
wisp
antibody
cells
polypeptide
cartilage
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2006526300A
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English (en)
Japanese (ja)
Other versions
JP2007505131A5 (https=
Inventor
デスノイヤーズ，ラック
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genentech Inc
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of JP2007505131A publication Critical patent/JP2007505131A/ja
Publication of JP2007505131A5 publication Critical patent/JP2007505131A5/ja
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Toxicology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2006526300A 2003-09-11 2004-09-09 Ｗｉｓｐアンタゴニストの使用方法 Pending JP2007505131A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US50201303P 2003-09-11 2003-09-11
PCT/US2004/029510 WO2005025603A2 (en) 2003-09-11 2004-09-09 Methods of using wisp antagonists

Publications (2)

Publication Number Publication Date
JP2007505131A true JP2007505131A (ja) 2007-03-08
JP2007505131A5 JP2007505131A5 (https=) 2007-08-30

Family

ID=34312341

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006526300A Pending JP2007505131A (ja) 2003-09-11 2004-09-09 Ｗｉｓｐアンタゴニストの使用方法

Country Status (6)

Country Link
US (1) US20060292150A1 (https=)
EP (1) EP1663288A2 (https=)
JP (1) JP2007505131A (https=)
AU (1) AU2004272066B8 (https=)
CA (1) CA2536396A1 (https=)
WO (1) WO2005025603A2 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019527193A (ja) * 2016-06-02 2019-09-26 ソシエテ・デ・プロデュイ・ネスレ・エス・アー サルコペニア及び筋損傷を治療する方法

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7455834B2 (en) 2002-06-29 2008-11-25 Genentech, Inc. Methods and compositions for modulating and detecting WISP activity
ATE476447T1 (de) 2002-06-29 2010-08-15 Genentech Inc Verfahren und zusammensetzungen zur modulation und zum nachweis von wisp-aktivität
EP1937306B1 (en) * 2005-08-19 2016-02-17 Janssen Biotech, Inc. Proteolysis resistant antibody preparations
FR2900155B1 (fr) * 2006-04-21 2008-06-27 Diana Naturals Sa Hydrolisat de cartilage aviaire, procede d'obtention et utilisations
KR102148303B1 (ko) 2012-02-11 2020-08-26 제넨테크, 인크. R-스폰딘 전위 및 그의 사용 방법

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7610396A (en) * 1996-11-08 1998-06-03 Human Genome Sciences, Inc. Connective tissue growth factor-3
WO1999062927A1 (en) * 1998-06-05 1999-12-09 Human Genome Sciences, Inc. Connective tissue growth factor-4
WO2001007085A1 (en) * 1999-07-23 2001-02-01 Case Western Reserve University Novel methods and reagents useful in the treatment of osteoarthritis
JP4202128B2 (ja) * 2000-10-16 2008-12-24 ジェネンテック・インコーポレーテッド Ｗｉｓｐポリペプチドを用いる治療方法
ATE476447T1 (de) * 2002-06-29 2010-08-15 Genentech Inc Verfahren und zusammensetzungen zur modulation und zum nachweis von wisp-aktivität

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
JPN6010041013, ＣＨＵＲＣＨ，Ｖ． ｅｔ ａｌ, "Ｔｈｅ ｒｏｌｅ ｏｆ ｗｉｓｐｓ ｉｎ ｃｈｏｎｄｒｏｃｙｔｅ ｄｉｆｆｅｒｅｎｔｉａｔｉｏｎ", Ｍｏｌｅｃｕｌａｒ Ｐａｔｈｏｌｏｇｙ, 2003, Ｖｏｌ．５６， Ｎｏ．２, ｐ．６９−７０ *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019527193A (ja) * 2016-06-02 2019-09-26 ソシエテ・デ・プロデュイ・ネスレ・エス・アー サルコペニア及び筋損傷を治療する方法

Also Published As

Publication number Publication date
WO2005025603A3 (en) 2006-04-27
EP1663288A2 (en) 2006-06-07
AU2004272066B2 (en) 2010-07-29
CA2536396A1 (en) 2005-03-24
US20060292150A1 (en) 2006-12-28
AU2004272066A1 (en) 2005-03-24
WO2005025603A2 (en) 2005-03-24
AU2004272066B8 (en) 2010-08-05

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