JP2007503473A - Ｎ−アシル化４−ヒドロキシフェニルアミン誘導体およびカフェインを含む相乗的組み合わせ - Google Patents
Ｎ−アシル化４−ヒドロキシフェニルアミン誘導体およびカフェインを含む相乗的組み合わせ Download PDFInfo
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- JP2007503473A JP2007503473A JP2006533699A JP2006533699A JP2007503473A JP 2007503473 A JP2007503473 A JP 2007503473A JP 2006533699 A JP2006533699 A JP 2006533699A JP 2006533699 A JP2006533699 A JP 2006533699A JP 2007503473 A JP2007503473 A JP 2007503473A
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/428—Thiazoles condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
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- A—HUMAN NECESSITIES
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Seasonings (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Detergent Compositions (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/459,911 US7064140B2 (en) | 2002-11-12 | 2003-06-12 | Synergistic combinations including N-acylated 4-Hydroxyphenylamine derivatives and caffeine |
| PCT/US2004/018514 WO2004110440A1 (en) | 2003-06-12 | 2004-06-10 | Synergistic combinations including n-acylated 4-hydroxyphenylamine derivatives and caffeine |
Publications (2)
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| JP2007503473A true JP2007503473A (ja) | 2007-02-22 |
| JP2007503473A5 JP2007503473A5 (cg-RX-API-DMAC7.html) | 2007-06-21 |
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| EP (1) | EP1635825B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2007503473A (cg-RX-API-DMAC7.html) |
| AT (1) | ATE409478T1 (cg-RX-API-DMAC7.html) |
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| CA (1) | CA2531829A1 (cg-RX-API-DMAC7.html) |
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| ES (1) | ES2315679T3 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2004110440A1 (cg-RX-API-DMAC7.html) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006053012A2 (en) * | 2004-11-10 | 2006-05-18 | Trinity Laboratories, Inc. | Novel pharmaceutical compositions for treating acquired chronic pain and associated dysphoria |
| US8026266B2 (en) | 2005-11-08 | 2011-09-27 | Arcion Therapeutics, Inc. | Treatment of length dependent neuropathy |
| TWI392670B (zh) * | 2006-06-22 | 2013-04-11 | Ucb Pharma Gmbh | 經取代的２-胺基萘滿之於製造用於預防、減緩及／或治療各種類型疼痛之藥物上的用途 |
| US10300031B2 (en) | 2007-08-06 | 2019-05-28 | Trinity Laboratories Inc. | Pharmaceutical compositions for treating chronic pain and pain associated with neuropathy |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH11509520A (ja) * | 1995-04-21 | 1999-08-24 | エルエスユー メディカル センター ファウンデーション | 鎮痛特性を有する新規のｎ−アセチル化４−ヒドロキシフェニルアミン誘導体及びそれを含む薬理組成物 |
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| US6864271B2 (en) * | 2002-11-12 | 2005-03-08 | The Foundation For The Lsu Health Sciences Center | Synergistic combinations including N-acylated 4-hydroxyphenylamine derivatives |
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2004
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- 2004-06-10 AU AU2004247138A patent/AU2004247138B2/en not_active Ceased
- 2004-06-10 DE DE602004016848T patent/DE602004016848D1/de not_active Expired - Lifetime
- 2004-06-10 JP JP2006533699A patent/JP2007503473A/ja active Pending
- 2004-06-10 WO PCT/US2004/018514 patent/WO2004110440A1/en not_active Ceased
- 2004-06-10 CA CA002531829A patent/CA2531829A1/en not_active Abandoned
- 2004-06-10 AT AT04754946T patent/ATE409478T1/de not_active IP Right Cessation
- 2004-06-10 ES ES04754946T patent/ES2315679T3/es not_active Expired - Lifetime
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH11509520A (ja) * | 1995-04-21 | 1999-08-24 | エルエスユー メディカル センター ファウンデーション | 鎮痛特性を有する新規のｎ−アセチル化４−ヒドロキシフェニルアミン誘導体及びそれを含む薬理組成物 |
Non-Patent Citations (7)
| Title |
|---|
| JPN5006016221, ＶＩＧＮＯＮ Ｅ, ＳＥＭＡＩＮＥ ＤＥＳ ＨＯＰＩＴＡＵＸ, 19990415, Ｖ７５ Ｎ１３−１４, Ｐ４１９−４２５ * |
| JPN5006016222, ＥＮＧＥＬＨＡＲＤＴ ＧＵＥＮＴＨＥＲ, ＡＲＺＮＥＩＭＩＴＴＥＬ−ＦＯＲＳＣＨＵＮＧ, 1997, Ｖ４７ Ｎ８, Ｐ９１７−９２７ * |
| JPN5006016224, ＧＯＬＤＳＴＥＩＮ ＪＥＲＯＭＥ, ＩＮＦＬＡＭＭＯＰＨＡＲＭＡＣＯＬＯＧＹ, 2001, Ｖ９ Ｎ１−２, Ｐ５１−６１ * |
| JPN6010049916, Ｉｌｓｅ Ｔｒｕｔｅｒ, Ｐｈａｒｍａｃｏｅｐｉｄｅｍｉｏｌｏｇｙ ａｎｄ Ｄｒｕｇ Ｓａｆｅｔｙ, 1998, ７, ｐ．９１−９７ * |
| JPN6010049917, Ｗｅｉ−Ｙａ Ｚｈａｎｇ, Ｄｒｕｇ Ｓａｆｅｔｙ, 2001, ２４， １５, ｐ．１１２７−１１４２ * |
| JPN6010049918, Ｇｕｉｌｌｅｒｍｏ Ｇｏｎｚａｌｅｚ−Ｍａｒｔｉｎ, Ｅｕｒｏｐｅａｎ Ｊｏｕｒｎａｌ ｏｆ Ｐｈａｒｍａｃｅｕｔｉｃｓ ａｎｄ Ｂｉｏｐｈａｒｍａｃｅｕｔｉｃｓ, 1998, ４６, ｐ．２９３−２９７ * |
| JPN6010049919, Ｐｏｌ Ｊ Ｐｈａｒｍａｃｏｌ Ｐｈａｒｍ, 1988, ４０， ３, ｐ．２２３−２３２ * |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2531829A1 (en) | 2004-12-23 |
| WO2004110440A1 (en) | 2004-12-23 |
| AU2004247138B2 (en) | 2009-03-19 |
| DE602004016848D1 (de) | 2008-11-13 |
| EP1635825B1 (en) | 2008-10-01 |
| ES2315679T3 (es) | 2009-04-01 |
| US20040254207A1 (en) | 2004-12-16 |
| US7064140B2 (en) | 2006-06-20 |
| EP1635825A1 (en) | 2006-03-22 |
| AU2004247138A1 (en) | 2004-12-23 |
| ATE409478T1 (de) | 2008-10-15 |
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