JP2007500205A5 - - Google Patents
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- Publication number
- JP2007500205A5 JP2007500205A5 JP2006531007A JP2006531007A JP2007500205A5 JP 2007500205 A5 JP2007500205 A5 JP 2007500205A5 JP 2006531007 A JP2006531007 A JP 2006531007A JP 2006531007 A JP2006531007 A JP 2006531007A JP 2007500205 A5 JP2007500205 A5 JP 2007500205A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- formula
- alkyl group
- mip synthase
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000001875 compounds Chemical class 0.000 claims 28
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 claims 11
- 101710113802 Inositol-3-phosphate synthase Proteins 0.000 claims 8
- 101710090028 Inositol-3-phosphate synthase 1 Proteins 0.000 claims 8
- 102100036881 Inositol-3-phosphate synthase 1 Human genes 0.000 claims 8
- 229910052739 hydrogen Inorganic materials 0.000 claims 5
- 239000001257 hydrogen Substances 0.000 claims 5
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 4
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 3
- 208000020016 psychiatric disease Diseases 0.000 claims 3
- 125000000217 alkyl group Chemical group 0.000 claims 2
- 239000003937 drug carrier Substances 0.000 claims 2
- 210000005171 mammalian brain Anatomy 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 208000020925 Bipolar disease Diseases 0.000 claims 1
- 101000998969 Homo sapiens Inositol-3-phosphate synthase 1 Proteins 0.000 claims 1
- 239000004480 active ingredient Substances 0.000 claims 1
- 210000004556 brain Anatomy 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 150000002431 hydrogen Chemical group 0.000 claims 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 1
- 239000003112 inhibitor Substances 0.000 claims 1
- 238000007918 intramuscular administration Methods 0.000 claims 1
- 238000007912 intraperitoneal administration Methods 0.000 claims 1
- 238000001990 intravenous administration Methods 0.000 claims 1
- 238000007911 parenteral administration Methods 0.000 claims 1
- 238000007920 subcutaneous administration Methods 0.000 claims 1
- 230000000699 topical effect Effects 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IL15620303A IL156203A0 (en) | 2003-05-29 | 2003-05-29 | Use of 2,2,3,3, tetramethylcyclopropane carboxylic acid derivatives for treating psychiatric disorders |
| PCT/IL2004/000455 WO2004105746A1 (en) | 2003-05-29 | 2004-05-27 | Use of 2,2,3,3, tetramethylcyclopropane carboxylic acid derivatives for treating psychiatric disorders |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007500205A JP2007500205A (ja) | 2007-01-11 |
| JP2007500205A5 true JP2007500205A5 (OSRAM) | 2007-07-12 |
Family
ID=32587598
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006531007A Pending JP2007500205A (ja) | 2003-05-29 | 2004-05-27 | 精神障害を治療するための２，２，３，３，テトラメチルシクロプロパンカルボン酸誘導体の使用 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20100048721A2 (OSRAM) |
| EP (1) | EP1626710B1 (OSRAM) |
| JP (1) | JP2007500205A (OSRAM) |
| AT (1) | ATE409469T1 (OSRAM) |
| CA (1) | CA2527094A1 (OSRAM) |
| DE (1) | DE602004016841D1 (OSRAM) |
| IL (2) | IL156203A0 (OSRAM) |
| WO (1) | WO2004105746A1 (OSRAM) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL157751A0 (en) | 2003-02-28 | 2004-03-28 | Yissum Res Dev Co | New amide derivatives of 2,2,3,3-tetramethylcyclopropane carboxylic acid, a method for their synthesis and pharmaceutical compositions containing them |
| US20060004098A1 (en) * | 2003-07-28 | 2006-01-05 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Compounds useful for treating neurological disorders |
| CN100426897C (zh) | 2005-01-12 | 2008-10-15 | 华为技术有限公司 | 分体式基站系统及其组网方法和基带单元 |
| CN102198121B (zh) * | 2011-04-08 | 2012-05-23 | 广东药学院 | 2,2,3,3-四甲基环丙酰硫脲在制备抗肿瘤药物中的应用 |
| US20140243422A1 (en) * | 2011-06-03 | 2014-08-28 | Elan Pharmaceuticals, Inc. | Methods of treating behavioral and psychiatric disorders |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9303274D0 (sv) * | 1993-10-07 | 1993-10-07 | Astra Ab | Novel phenylethyl and phenylproplamines |
| IL108595A (en) * | 1994-02-08 | 1998-09-24 | Yissum Res Dev Co | History of Carboxylic Acid 2,2,3,3 Tetramethyl Cyclophen (ACMT) (Process for their Preparation and Pharmaceutical Preparations Containing Them) |
| CN1251758C (zh) * | 2000-07-21 | 2006-04-19 | 特瓦制药工业有限公司 | 丙戊酸和2－丙基戊烯酸酰胺的衍生物在制备治疗双极情感障碍症躁狂病药物中的用途 |
| US6610326B2 (en) * | 2001-02-16 | 2003-08-26 | Andrx Corporation | Divalproex sodium tablets |
| IL147953A (en) * | 2002-02-01 | 2008-04-13 | Meir Bialer | Derivatives and pharmaceutical compositions of n-hydroxymethyl tetramethylcyclopropyl- |
-
2003
- 2003-05-29 IL IL15620303A patent/IL156203A0/xx unknown
-
2004
- 2004-05-27 WO PCT/IL2004/000455 patent/WO2004105746A1/en not_active Ceased
- 2004-05-27 EP EP04735084A patent/EP1626710B1/en not_active Expired - Lifetime
- 2004-05-27 CA CA002527094A patent/CA2527094A1/en not_active Abandoned
- 2004-05-27 DE DE602004016841T patent/DE602004016841D1/de not_active Expired - Lifetime
- 2004-05-27 JP JP2006531007A patent/JP2007500205A/ja active Pending
- 2004-05-27 US US10/558,408 patent/US20100048721A2/en not_active Abandoned
- 2004-05-27 AT AT04735084T patent/ATE409469T1/de not_active IP Right Cessation
-
2005
- 2005-11-23 IL IL172134A patent/IL172134A/en not_active IP Right Cessation
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