JP2007330572A - Syringe pump - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a syringe pump where a plunger knob part of a micro-syringe is held reliably by disengaging engaging of a feed screw and a carriage when moving of the carriage stops. <P>SOLUTION: The carriage 18 is provided with: a guide hole 18b for putting a guide member 16 through movably in an axial direction; a plunger knob part holding part 25; an engaging part 19 which engages with the feed screw 20; and a latch member 26 which holds the knob part of a plunger on a proximal end surface on the side of a cylinder body holding member of the carriage 18. The latch member 26 is provided with: rotating arms 26a and 26b; a connection member 26c; and a coil spring 27 which biases the latch member 26 to a side opposite to a cylinder body holding member with respect to a carriage main body 18a. The rotating arm 26a on the side of the cylinder body holding member is provided with: a notch part which the plunger can be put through; and a pin and a pin insertion hole which regulate rotation of the latch member 26 while the knob part is held. <P>COPYRIGHT: (C)2008,JPO&INPIT

Description

  The present invention relates to a syringe pump, and more particularly to a pump that delivers liquid from a syringe or a microsyringe, and is particularly suitable for adding and injecting a small amount of liquid sample from a microsyringe into a reaction vessel in an organic synthesis experiment. This relates to a syringe pump.

Conventionally, a syringe pump has been used as a device for automatically sending a drug solution or the like sucked into a syringe toward a patient or the like. A general syringe pump is known in which a fixing mechanism for fixing a cylinder body, a pressing mechanism for pressing a plunger, and a control unit for controlling the operation of the pressing mechanism are integrated. (For example, refer to Patent Document 1).
JP 2004-24884 A

  However, when a screw feeding mechanism is used as a pushing mechanism for pushing the plunger, if the plunger stops for some reason, a strong force continues to act on the plunger by the pushing force from the screw feeding mechanism. Therefore, a thin plunger such as a microsyringe may be bent by the pressing force.

  In addition, in a conventional syringe pump for a syringe, it is sufficient to simply push the plunger knob, and there is almost no problem. However, when pushing the thin plunger of the microsyringe, the plunger knob is placed in a predetermined position. It is necessary to accurately push in the axial direction of the plunger while securely holding it, and if the knob is pushed in an inclined state, the plunger may be bent by the pushing force in this case as well.

  Therefore, an object of the present invention is to provide a syringe pump that can prevent a strong force from being applied to the plunger even when the movement of the plunger stops, and can reliably hold the knob portion of the plunger. Yes.

  In order to achieve the above object, a syringe pump of the present invention includes a cylinder body holding member that holds a cylinder body of a microsyringe, a guide member that extends from one side of the cylinder body holding member, and the guide member. A micro-syringe plunger held by the cylinder body holding member, and a carriage screw arranged parallel to the guide member, and a motor for rotationally driving the feed screw. In a syringe pump that rotates the feed screw and linearly moves the carriage along the guide member to push the plunger and deliver the liquid in the microsyringe, the carriage includes the carriage A guide hole through which the guide member is movably inserted in the axial direction, and a knob for the plunger A plunger knob holding portion that holds the knob, an engagement portion that engages with the feed screw, and a knob holding member for holding the knob on a base end surface of the carriage on the cylinder body holding member side, A knob holding member is provided on the cylinder body holding member side and the anti-cylinder body holding member side of the carriage main body, each of the guide members being movable in the axial direction, and a rotating arm provided rotatably in the circumferential direction, A connecting member for connecting the rotating ends of both rotating arms; and a biasing means for biasing the knob holding member toward the side opposite to the cylinder body holding member with respect to the carriage body, the cylinder body holding member side The rotating arm is provided with a notch portion through which the plunger can be inserted and a restricting portion for restricting the rotation of the knob holding member while holding the knob portion. A knob holding member is placed at a position where the knob is sandwiched between the carriage body side surface of the rotating arm on the cylinder body holding member side biased toward the holding member side and the cylinder body holding member side surface of the carriage body. When it is rotated, the plunger is in a state of being inserted through the notch, and the rotation of the knob holding member is restricted by the restricting portion.

  In addition, the engaging portion has a plurality of rollers arranged around the feed screw with their axes parallel to each other, and the plurality of rollers can move in the radial direction with respect to the feed screw and move in the axial direction. A case portion having a feed screw insertion hole having an inner diameter larger than the outer diameter of the feed screw and a roller shaft projecting from both ends of the case portion. Biasing means for biasing in the surface direction, and parallel grooves having a pitch equal to the screw pitch of the feed screw are provided on the peripheral surface of each roller.

  Further, three rollers that engage with the feed screw are provided at equal intervals in the circumferential direction of the feed screw, and are arranged in the case portion while being shifted in the axial direction by 1/3 pitch of the screw pitch. It is characterized by being.

  According to the present invention, the knob portion of the plunger can be securely held on the surface of the carriage on the cylinder body holding member side, and the thin plunger of the microsyringe of about 10 μl can be accurately pushed in the axial direction.

  In addition, by engaging a plurality of rollers provided with parallel grooves on the peripheral surface with the feed screw in a state of being urged by the urging means, the feed screw rotated by the motor and the parallel groove are normally engaged with each other. The carriage can be moved, and when the movement of the carriage stops, the meshing state is released by moving the roller in the radiation direction with respect to the feed screw that continues to rotate. The feed screw, motor, etc. can be protected.

  FIG. 1 shows an embodiment of the syringe pump according to the present invention. FIG. 1 is an explanatory view showing an example of a usage state in which the pump body is mounted on a free arm. FIG. 2 is a front view of the pump body in a state where a micro syringe is mounted. 3 is a plan view of the pump body, FIG. 4 is an explanatory view of a feed screw, a roller, and a spring member, FIG. 5 is an explanatory view of a carriage, FIG. 6 is a sectional view taken along VI-VI in FIG. 6 is a cross-sectional plan view of FIG.

  The syringe pump shown in this embodiment is formed by a pump main body 12 to which the microsyringe 11 is attached and an operation unit 14 which is a control means electrically connected to the pump main body 12 via a signal cable 13. The microsyringe 11 is a well-known microsyringe used for injecting a small amount of reagent of several microliters to several milliliters into a reaction vessel little by little in an organic synthesis experiment or the like, and the cylinder body 11a has an outer diameter of 6 to 6. A commercially available microsyringe having a stroke of about 9 mm and a maximum stroke of the plunger 11 b of about 70 mm can be used. The operation panel of the operation unit 14 is provided with various buttons 14a for performing various settings, a display unit 14b for operation confirmation, and the like, and control units such as a calculation unit, a storage unit, and an input / output unit are provided therein. It is stored.

  The pump body 12 includes a cylinder body holding member 15 that detachably holds the cylinder body 11a of the microsyringe 11, and a guide in which a pair of round bars are extended in parallel from one side of the cylinder body holding member 15 at a predetermined interval. Member 16 and reinforcing member 16a, cylinder body mounting position restricting member 17 movably provided on the base side (cylinder body holding member 15 side) of guide member 16 and reinforcing member 16a, and cylinder body mounting position restricting member 17 is engaged with a carriage 18 movably provided along the guide member 16 on the front end side from 17 and an engaging portion 19 provided in parallel to the guide member 16 and provided on the carriage 18. A feed screw 20, a motor 21 that rotationally drives the feed screw 20, and a plunger top dead center side movement limit of the carriage 18 are detected. A limit switch 22 for stopping the motor 21 and includes an encoder 23 for detecting the rotational speed of the motor 21.

  The cylinder body holding member 15 is provided so as to be rotatable about a V-shaped groove 15b provided on one surface of a holding member body 15a having a flat rectangular parallelepiped shape and a rotation axis parallel to the V-shaped groove 15b. An arc-shaped clamp arm 15c, a lock nut 15d for opening and closing the clamp arm 15c, and a support member mounting portion 15e used when the pump body 12 is attached to an experimental stand, a camera tripod, a universal arm, or the like. ing.

  The microsyringe 11 is detachable from the V-shaped groove 15b when the lock nut 15d is turned to open the clamp arm 15c, and the cylinder body 11a of the microsyringe 11 is placed in the V-shaped groove 15b. In this state, the cylinder body 11a is sandwiched and held between the V-shaped groove 15b and the clamp arm 15c by turning the lock nut 15d to move the clamp arm 15c toward the closed position.

  The guide member 16 extends from one end surface of the holding member main body 15a on one side of the cylinder body holding member 15 and perpendicular to one end of the V-shaped groove 15b in a direction parallel to the axis of the V-shaped groove 15b. The base end portions of the guide member 16 and the reinforcing member 16a are inserted into the pair of holding holes of the motor fixing plate 24 fixed to the one end face of the holding member main body 15a, and screwed from the side of the holding hole. It is fixed with fixed fixing bolts. Moreover, the front-end | tip part of the guide member 16 and the reinforcing material 16a is hold | maintained by the end member 16b.

  The motor fixing plate 24 is for fixing the motor 21 at a predetermined position as well as fixing the guide member 16 and the reinforcing material 16a. The clamp arm 15c is at an open position with respect to the holding member main body 15a. The motor 21 is fixed at a position opposite to the protruding direction at a certain time.

  The motor 21 is a small stepping motor or a small DC motor that can control the rotational speed (rotation angle) of the drive shaft. A reduction gear head 21a is mounted on the drive shaft side, and on the non-drive shaft side. Has an integral unit structure on which the encoder 23 for detecting the rotational speed of the drive shaft is mounted. The shaft screw protruding from the gear head 21a is connected to the feed screw 20 via a coupling 21b. By attaching the end of the gear head 21a to the motor fixing plate 24, the shaft is adjacent to the holding member main body 15a. The motor 21 is fixed. The feed screw 20 having the base end connected to the coupling 21b is held at the tip by the end member 16b, so that its axis is parallel to the axis of the V-shaped groove 15b and the guide member 16. In addition, by measuring the rotation speed of the motor 21 with the encoder 23, the rotation speed of the feed screw 20 can be accurately calculated, and by this, the position and movement amount of the carriage 18 can be grasped, thereby providing a highly accurate liquid supply. Is possible.

  The cylinder body mounting position restricting member 17 provided on the base side of the guide member 16 is composed of a plate-like body having a pair of insertion holes through which the guide member 16 and the reinforcing material 16a are inserted. It is formed so that it can be fixed at an arbitrary position of the guide member 16 by a fixing screw 17a screwed from the side of the insertion hole in a state where the member 16 and the reinforcing member 16a are inserted.

  On one side of the cylinder body mounting position restricting member 17, a restricting surface 17b with which the outer end surface of the flange 11c provided at the rear end of the cylinder body 11a abuts is formed, and the flange 11c is formed on the restricting surface 17b. By holding the cylinder body 11a on the cylinder body holding member 15 in a state where the outer end surfaces of the cylinder body 11a are in contact with each other, the cylinder body 11a of the microsyringe 11 can be attached at a fixed position. The cylinder body mounting position restricting member 17 is equipped with the limit switch 22 in which an operating element 22a protrudes from the restricting surface 17b to the carriage 18 side.

  Normally, the cylinder body mounting position restricting member 17 is positioned so that the needle 11d protrudes more sufficiently than the cylinder body holding member 15 and the encoder 24 when the outer end surface of the flange 11c is brought into contact with the restricting surface 17b. For example, the base of the needle 11d is set so as to protrude from the cylinder body holding member 15 and the encoder 24.

  The carriage 18 is provided so as to be linearly movable by inserting the distal end side of the guide member 16 from the cylinder body mounting position restricting member 17 into a guide hole 18b provided in the carriage body 18a. The carriage 18 is integrally formed with a plunger knob holding part 25 that detachably holds the knob 11e of the plunger 11b, the engagement part 19, and a switch pushing part 25a that operates the limit switch 22. Has been.

  The switch pusher 25a pushes the operating element 22a at the top dead center side movement limit in which the carriage 18 has moved in the direction of the cylinder body mounting position restricting member 17, and operates the limit switch 22. It is set so that the motor 21 is stopped by the operation of and the plunger 11b does not advance beyond the top dead center. Note that, at the top dead center of the plunger 11b, the microsyringe 11 having a different interval between the flange 11c and the knob 11e can be dealt with by adjusting the position of the limit switch 22.

  The plunger knob holding part 25 has a latch member 26 which is a knob holding member for pressing and holding the knob 11e against the cylinder body holding member side surface of the carriage body 18a. The latch member 26 is pivotally provided on the cylinder body holding member side and the anti-cylinder body holding member side of the carriage body 18a so as to be movable in the axial direction and rotatable in the circumferential direction, respectively. Arms 26a, 26b, a connecting member 26c for connecting the rotating ends of both rotating arms 26a, 26b, and an urging force for urging the latch member 26 toward the cylinder body holding member with respect to the carriage body 18a. And a coil spring 27 as means.

  The latch member 26 is formed in a bowl shape straddling the carriage body 18a by the rotating arms 26a and 26b and the connecting member 26c, and the rotating arm 26a on the cylinder body holding member side has a bush 28 inserted through the guide member 16. The rotating arm 26 b on the side opposite to the cylinder body holding member is attached to the guide member 16 via a retainer 29 inserted through the guide member 16. As a result, the latch member 26 is movably attached to the guide member 16 via the bush 28 and the retainer 29, and is rotatably attached to the holding position (position indicated by the solid line in FIG. 5) and the non-holding position. (Position shown by a broken line in FIG. 5).

  Further, a medium diameter spring accommodating hole 18c for accommodating the coil spring 27 and a large diameter for movably accommodating the retainer 29 are provided on the side opposite to the cylinder body holding member of the small diameter guide hole 18b provided in the carriage body 18a. The retainer receiving hole 18d is continuously provided, and the coil spring 27 is contracted between the spring receiving hole 18c and the inner periphery of the retainer 29. The rotating arm 26a is provided with a notch 26d through which the plunger 11b can be inserted, and a pin insertion hole 26f through which a pin 26e protruding from the carriage body 18a can be inserted. The notch 26d is in a state in which the plunger 11b is inserted when the knob 11e of the microsyringe 11 arranged at a predetermined position is held, and at the same time, the pin 26e is inserted into the pin insertion hole 26f, thereby rotating the latch member 26. It becomes a regulated state.

  The plunger knob holding portion 25 formed in this way is formed on the carriage body side surface of the rotating arm 26a on the cylinder body holding member side which is urged toward the anti-cylinder body holding member side by the coil spring 27 and the carriage body 18a. The knob portion 11e is sandwiched between the cylinder body holding member and the surface of the cylinder body holding member, and the knob portion 11e is held in a state of being constantly pressed by the carriage body 18a. Further, in the holding state of the knob portion 11e, the plunger 11b is inserted into the notch portion 26d, and the surface on the carriage body side of the rotating arm 26a around the notch portion 26d is the surface on the cylinder body holding member side of the carriage body 18a. Since almost the entire knob portion 11e is pressed in a parallel state, even if the tip of the knob portion 11e protrudes in a spherical shape, it can be reliably held without rattling. Further, in this holding state, the pin 26e and the pin insertion hole 26f are engaged with each other to become the rotation restricting portion of the latch member 26, so that the holding state of the knob portion 11e can be reliably maintained. Moreover, even if the thickness of the knob | pick part 11e differs by setting the protrusion length of the pin 26e and the moving dimension of the latch member 26 in consideration of the thickness of the knob | pick part 11e of various micro syringes 11. FIG. The knob 11e can be securely held.

  The engagement portion 19 has three rollers 30 arranged at equal intervals of 120 degrees in the circumferential direction with the axis line parallel to the periphery of the feed screw 20, and radiates the roller 30 to the feed screw 20. A case portion 19b having a feed screw insertion hole 19a having an inner diameter larger than the outer diameter of the feed screw 20, and holding the turnable state in a state where movement in the axial direction and movement in the axial direction are restricted, and the case portion A spring member 31 is provided as a biasing means for biasing the roller shaft 30a protruding from both ends of 19b in the circumferential surface direction of the feed screw 20. About 10 V-shaped parallel grooves 30 b having a pitch equal to the thread pitch of the feed screw 20 are provided on the peripheral surface of each roller 30.

  The case portion 19b protrudes from the carriage body 18a in the direction of the feed screw 20, and is a width obtained by adding 2/3 of the thread pitch of the feed screw 20 to the length of the roller 30 or slightly more than that. A roller accommodating portion 19c having a large dimension is provided, and the feed screw insertion hole 19a is provided at the center of both walls of the roller accommodating portion 19c. Around the feed screw insertion hole 19a, the axis of the feed screw 20 is provided. On the other hand, three roller shaft insertion holes 19d that are long in the radial direction are provided. The spring member 31 is formed in a substantially C shape, is suspended on the outer side of each roller shaft 30a protruding from both side surfaces of the case portion 19b, is bent at both ends inwardly, and is detached from the roller shaft 30a. Is preventing. In addition, E-rings 32 are fitted to both ends of each roller shaft 30a to prevent the roller shaft 30a and the spring member 31 from coming off.

  The three rollers 30 are accommodated in the roller accommodating portion 19c in a state in which the feed screw 20 and the parallel groove 30b are engaged with each other and are shifted in the axial direction by 1/3 pitch of the screw pitch. One roller end surface of the three rollers 30 abuts against the wall inner surface of the roller housing portion 19c on the cylinder body holding member side, and the end surface of the other roller 30 contacts the wall inner surface on the side opposite to the cylinder body holding member. It is in contact. Further, the feed screw 20 is rotatably held at the center of the three rollers 30 and penetrates the feed screw insertion hole 19a in a non-contact manner.

  When liquid medicine is fed from the microsyringe 11 using the syringe pump formed in this way, first, the microsyringe 11 that has sucked the chemical liquid more than the liquid feeding amount is attached to the pump body 12.

  The mounting of the microsyringe 11 on the pump body 12 is performed by adjusting the position of the cylinder body mounting position restricting member 17 using the empty microsyringe 11 in advance, and then opening the clamp arm 15c to make the cylinder body 11a of the microsyringe 11 Is placed in the V-shaped groove 15b, and the outer end surface of the flange 11c is brought into contact with the regulating surface 17b of the cylinder body mounting position regulating member 17. Further, the latch member 26 of the plunger knob holding portion 25 is pushed toward the cylinder body holding member against the coil spring 27 to release the engagement between the pin 26e and the pin insertion hole 26f, and then the latch member. 26 is rotated around the guide member 16 to the non-holding position on the side opposite to the engaging portion. The latch member 26 in the rotating state is prevented from rotating when the rotating arm 26a comes into contact with the pin 26e, and is prevented from rotating carelessly.

  Next, the pull-out length of the plunger 11b is adjusted so that the tip of the knob 11e abuts against the cylinder body holding member side surface of the carriage body 18a, and the latch member 26 is pushed toward the cylinder body holding member while being held. When it is rotated toward, the plunger 11b first enters the notch 26d. Furthermore, when the latch member 26 is pushed and rotated until the pin insertion hole 26f is turned to the position of the pin 26e and then the pushing force of the latch member 26 is released, the latch member 26 is moved by the urging force of the coil spring 27. Then, the pin 26e enters the pin insertion hole 26f and is prevented from rotating, and the rotating arm 26a presses the knob 11e against the carriage body 18a. As a result, the knob portion 11e is uniformly pressed and held by the carriage body 18a by the rotating arm 26a, and even if the tip of the knob portion 11e protrudes in a hemispherical shape, the knob portion 11e does not tilt. Can be held in.

  On the other hand, in the cylinder body holding member 15, the lock nut 15 d is tightened to close the clamp arm 15 c, the cylinder body 11 a is sandwiched between the V-shaped groove 15 b and the clamp arm 15 c, and the microsyringe 11 is fixed to the pump body 12. Thus, by holding the cylinder body 11a between the V-shaped groove 15b and the clamp arm 15c, the microsyringe 11 of various dimensions can be reliably held in the pump body 12.

  Next, the feed screw 20 is rotated in the discharge direction by the motor 21, and the carriage 18 is advanced along the guide member 16 to the top dead center of the plunger 11b. In this state, the position of the limit switch 22 is adjusted, and it is confirmed that the operation unit 14 has recognized the top dead center, and the limit switch 22 is fixed.

  After adjusting each part in this manner, the microsyringe 11 is once removed from the pump body 12 to suck a predetermined amount of chemical solution, and the operation unit 14 is operated to move the feed screw 20 by the motor 21 in the liquid feeding direction. Is rotated in the opposite direction, and the carriage 18 is retracted along the guide member 16 so that the position of the plunger knob holding part 25 corresponds to the position of the knob 11e in the state of sucking the chemical solution, as described above. The microsyringe 11 that has sucked the chemical solution is attached to the pump body 12.

  At this time, it is not necessary for the microsyringe 11 to suck the same amount of the chemical solution as the liquid supply amount, and the excess amount may be discharged after the chemical solution is sucked more than the liquid supply amount. Further, since the carriage 18 is moved by the operation of the motor 21, the operation unit 14 counts the number of rotations of the feed screw 20 by a signal from the encoder 23 and stores the position of the carriage 18.

  When the entire amount of the chemical solution in the microsyringe 11 is fed at a predetermined flow rate, the feeding time is input to the operation unit 14. Since the operation unit 14 stores the number of rotations of the feed screw 20 until the carriage 18 is moved from the top dead center position where the limit switch 22 is operated to the current position, this speed is divided by time. By rotating the feed screw 20 in the discharge direction, the entire amount of the chemical solution can be discharged and fed within that time.

  At this time, the carriage 18 is rotated by the feed screw 20 inserted through the engaging portion 19, whereby each roller 30 is biased by the spring member 31 to the feed screw 20, and each parallel groove 30 b is engaged. Therefore, each roller 30 moves along the feed screw 20 and the carriage 18 moves in the discharge direction when the end face of the roller 30 located closest to the discharge direction presses the wall surface of the roller accommodating portion 19c. When the carriage 18 moves, the three rollers 30 serve as bearings, and each roller 30 is rotated by the rotation of the feed screw 20, so that a conventional screw feed mechanism using a female screw is used. Compared to the above, the driving torque of the feed screw 20 can be greatly reduced. Even when a foreign object is caught in the screw surface, the carriage 18 can be reliably moved as long as one of the three rollers 30 is engaged with the feed screw 20. Along with the movement of the carriage 18, the plunger 11b of the microsyringe 11 is pushed and the chemical solution in the microsyringe 11 is sent out from the needle 11d. Further, by setting the gap between the front and rear ends of the three rollers 30 and the inner wall of the roller accommodating portion 19c as small as possible, for example, 1/3 or less of the screw pitch, the rotation of the feed screw 20 and the amount of movement of the carriage 18 are achieved. The error is in a negligible range. Further, since the three rollers 30 are movable in the radial direction of the feed screw 20, the engaged state can be maintained even if the positional relationship with the feed screw 20 is slightly deviated.

  When the movement of the carriage 18 stops for some reason, the roller 30 positioned closest to the carriage movement direction, for example, the discharge side is pressed against the wall surface of the roller accommodating portion 19c with a strong force by the action of the feed screw 20 that continues to rotate. At the same time, due to the effect of the screw slope, it receives a force in a direction away from the thread that meshes, and when the force in the direction away from the thread exceeds the urging force of the spring member 31, the roller shaft 30a becomes the roller shaft. It moves to the outer peripheral side along the insertion hole 19d, and the projecting portion of the parallel groove 30b climbs over the thread and gets over, and moves to the next thread portion by the screw pitch and meshes. When the first roller 30 moves by the screw pitch, the second roller 30 receives the aforementioned force and moves over the screw thread and moves by the screw pitch. While the feed screw 20 is rotating, Each roller 30 repeats the mountain overpass. Therefore, when the carriage 18 is stopped, the engaging portion 19 acts as a torque limiter, and no excessive force is applied to the carriage 18, the feed screw 20, the motor 21, etc., and these can be protected. Further, even if one roller 30 is removed, the other two rollers 30 are kept in an engaged state, so that the carriage 18 is not in a free state.

  In addition, since the roller 30 also has a function as a bearing as described above, it is necessary to provide the roller 30 so as to surround the feed screw 20, so that three or more rollers are required. Since the diameter of a roller becomes small, three is optimal. Further, the setting of the limit switch 22 and the operation unit 14 may be appropriately set according to the diameter of the microsyringe 11 and the delivery condition of the chemical solution, and the shape and function of the operation unit 14 are arbitrary.

It is explanatory drawing which shows an example of the use condition which attached the pump main body to the universal arm. It is a front view of the pump main body with the microsyringe attached. It is a top view of a pump main body similarly. It is explanatory drawing of a feed screw, a roller, and a spring member. It is explanatory drawing of a carriage. It is VI-VI sectional drawing of FIG. FIG. 7 is a cross-sectional plan view of FIG. 6.

Explanation of symbols

  DESCRIPTION OF SYMBOLS 11 ... Micro syringe, 11a ... Cylinder body, 11b ... Plunger, 11c ... Flange, 11d ... Needle, 11e ... Knob part, 12 ... Pump main body, 13 ... Signal cable, 14 ... Operation unit, 15 ... Cylinder body holding member, 15a ... Holding member main body, 15b ... V-shaped groove, 15c ... Clamp arm, 15d ... Lock nut, 16 ... Guide member, 16a ... Reinforcing material, 16b ... End member, 17 ... Cylinder body mounting position restricting member, 17a ... Fixing screw, 17b: Restricting surface, 18 ... Carriage, 18a ... Carriage body, 18b ... Guide hole, 18c ... Spring housing hole, 18d ... Retainer housing hole, 19 ... Engagement part, 19a ... Feed screw insertion hole, 19b ... Case part, 19c ... Roller receiving hole, 19b ... Roller shaft insertion hole, 20 ... Feed screw, 21 ... Motor, 22 ... Mitt switch, 22a ... operator, 23 ... encoder, 24 ... motor fixing plate, 25 ... plunger knob holding part, 25a ... switch pushing part, 26 ... latch member, 26a, 26b ... rotating arm, 26c ... connecting member , 26d ... notch, 26e ... pin, 26f ... pin insertion hole, 27 ... coil spring, 28 ... bush, 29 ... retainer, 30 ... roller, 30a ... roller shaft, 30b ... parallel groove, 31 ... spring member, 32 ... E-ring

Claims (4)

  A cylinder body holding member for holding a cylinder body of the microsyringe, a guide member extending from one side of the cylinder body holding member, a carriage provided movably along the guide member, and the guide member A feed screw arranged in parallel; and a motor that rotationally drives the feed screw; the plunger of the microsyringe held by the cylinder body holding member is held by the carriage; and the feed screw is rotated to move the carriage. In the syringe pump that pushes the plunger and sends out the liquid in the microsyringe by linearly moving along the guide member, the carriage includes a guide hole through which the guide member is movably inserted in the axial direction. A plunger knob holding portion for holding the plunger knob, and the feed screw An engaging portion to be engaged, and a knob holding member for holding the knob on a base end surface of the carriage on the cylinder body holding member side, the knob holding member including the carriage body on the cylinder body holding member side and On the non-cylinder body holding member side, each of the guide members is movable in the axial direction and pivotally provided so as to be pivotable in the circumferential direction, and a coupling that connects between the pivot ends of both the pivot arms. A notch portion through which the plunger can be inserted into the rotating arm on the cylinder body holding member side, and a biasing means for biasing the knob holding member toward the side opposite to the cylinder body holding member with respect to the carriage body And a restricting portion for restricting the rotation of the knob holding member in a state where the knob is held, and the cylinder body holding member side biased by the biasing means toward the anti-cylinder body holding member side. When the knob holding member is rotated to a position where the knob is sandwiched between the carriage arm surface of the moving arm and the cylinder body holding member side surface of the carriage body, the plunger passes through the notch. The syringe pump is characterized by being in a state where the rotation of the knob holding member is restricted by the restricting portion.   A cylinder body holding member for holding a cylinder body of the microsyringe, a guide member extending from one side of the cylinder body holding member, a carriage provided movably along the guide member, and the guide member A feed screw arranged in parallel; and a motor that rotationally drives the feed screw; the plunger of the microsyringe held by the cylinder body holding member is held by the carriage; and the feed screw is rotated to move the carriage. In the syringe pump that pushes the plunger and sends out the liquid in the microsyringe by linearly moving along the guide member, the carriage includes a guide hole through which the guide member is movably inserted in the axial direction. A plunger knob holding portion for holding the plunger knob, and the feed screw An engaging portion that engages, and a knob holding member for holding the knob on a base end surface of the carriage on the cylinder body holding member side, the engaging portion having an axis parallel to the periphery of the feed screw A plurality of rollers arranged toward the head, and the plurality of rollers are rotatably held in a state in which the rollers can be moved in a radial direction with respect to the feed screw and the movement in the axial direction is restricted, and the outside of the feed screw. A case portion having a feed screw insertion hole having an inner diameter larger than the diameter, and a biasing means for biasing a roller shaft protruding from both ends of the case portion in the circumferential direction of the feed screw, A syringe pump characterized in that parallel grooves having a pitch equal to the thread pitch of the feed screw are provided on the peripheral surface.   A cylinder body holding member for holding a cylinder body of the microsyringe, a guide member extending from one side of the cylinder body holding member, a carriage provided movably along the guide member, and the guide member A feed screw arranged in parallel; and a motor that rotationally drives the feed screw; the plunger of the microsyringe held by the cylinder body holding member is held by the carriage; and the feed screw is rotated to move the carriage. In the syringe pump that pushes the plunger and sends out the liquid in the microsyringe by linearly moving along the guide member, the carriage includes a guide hole through which the guide member is movably inserted in the axial direction. A plunger knob holding portion for holding the plunger knob, and the feed screw An engaging portion to be engaged, and a knob holding member for holding the knob on a base end surface of the carriage on the cylinder body holding member side, the knob holding member including the carriage body on the cylinder body holding member side and On the non-cylinder body holding member side, each of the guide members is movable in the axial direction and pivotally provided so as to be pivotable in the circumferential direction, and a coupling that connects between the pivot ends of both the pivot arms. A notch portion through which the plunger can be inserted into the rotating arm on the cylinder body holding member side, and a biasing means for biasing the knob holding member toward the side opposite to the cylinder body holding member with respect to the carriage body And a restricting portion for restricting the rotation of the knob holding member in a state where the knob is held, and the cylinder body holding member side biased by the biasing means toward the anti-cylinder body holding member side. When the knob holding member is rotated to a position where the knob is sandwiched between the carriage arm surface of the moving arm and the cylinder body holding member side surface of the carriage body, the plunger passes through the notch. A state in which the rotation of the knob holding member is restricted by the restricting portion, and the engaging portion includes a plurality of rollers disposed around the feed screw with their axes parallel to each other, and the plurality of rollers. A roller having a feed screw insertion hole having an inner diameter larger than an outer diameter of the feed screw and holding the roller in a radially movable manner with respect to the feed screw and being rotatable in a state where movement in the axial direction is restricted And a biasing means for biasing roller shafts protruding from both ends of the case portion in the circumferential direction of the feed screw, and the circumferential surface of each roller is equal to the screw pitch of the feed screw Pi A syringe pump characterized in that a parallel groove is provided.   The roller is provided in the case portion in a state where three rollers are provided at equal intervals in the circumferential direction of the feed screw and are shifted in the axial direction by 1/3 pitch of the screw pitch. Item 4. The syringe pump according to Item 2 or 3.

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