JP2007307084A - Method for estimating whitening effect by measuring blood circulation - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a method for estimating whitening effect by measuring an increase in whiteness of the skin color due to a skin color change caused by promoted blood circulation. <P>SOLUTION: The method for estimating whitening effect comprises a step of measuring skin spectra by means of a colorimeter before and after being subjected to a whitening effect promoting treatment, a step of calculating an increase rate of average total-hemoglobin content of the skin region before and after the treatment on the basis of the measured skin spectra, and a step of determining whitening effect on the basis of the increase rate of average total-hemoglobin content. The whitening effect promoting treatment is performed on the forehead, under the eyes and the cheek. Whitening effect is determined to be effective when the increase rate of average total-hemoglobin content is ≥10% and ≤20%. <P>COPYRIGHT: (C)2008,JPO&INPIT

Description

  The present invention relates to a whitening evaluation method, and more particularly to a skin whitening effect evaluation method by measuring a blood circulation state.

  Conventionally, in general color measurement, light is incident and the reflectance of the light is logically developed as starting data, which is defined in JIS and used in a wide range of fields. For example, skin color is also measured by this technique, so light of a specific wavelength is incident on the surface of the skin, and the reflected light is received to determine the reflectance of the skin at the specific wavelength. The whitening effect has been evaluated by paying attention to the amount of melanin, which is a black-brown to black pigment.

In the skin color measurement, it is an optical requirement that whiteness increases the reflectance of light, and the condition is that there are few pigments, for example, melanin pigments, as light absorbers of the skin. Therefore, many of whitening cosmetics, a decrease of melanin, increasing the brightness of the skin associated therewith, i.e., L ^* a ^* b ^* in the case of the color system L ^* value increased whitening effect of (whiteness) In the evaluation of the whitening effect when these whitening cosmetics are used, the reflectance of light is enhanced by the decrease in the decreased melanin pigment, and the increased skin lightness, that is, the L ^* value (whiteness ) Has been used as a criterion.

  However, current color science technology is not perfect, and cases have been reported that do not necessarily match the sensory “appearance” in vision, and sensory “appearance” may be considered as an effective evaluation criterion. . In particular, since the color is determined by simple reflection and absorption of light in skin color measurement, there is a problem that the element of “appearance” of the skin is not accurately reflected.

In addition to melanin pigments, hemoglobin components are listed as components that contribute to the skin color, and the relationship with the surface condition of the skin has been studied.
Japanese Patent Laid-Open No. 10-127585 JP 2005-34355 A JP 2003-275179 A JP 2002-200050 A JP 2004-283357 A JP 2004-216011 A

  Therefore, the present invention has been made in view of the above, and an object of the present invention is to provide a method of applying an increase in the whiteness of the skin color caused by the skin color change caused by blood circulation promotion to the evaluation of the whitening effect.

  In addition to normal skin color measurement, the inventors calculated the amount of melanin and hemoglobin in the skin, analyzed the relationship between the change in the amount of hemoglobin and the appearance of the skin color, and the increase in hemoglobin increased the whiteness of appearance. As a result, the present invention has been developed.

  That is, the invention according to claim 1 includes a step of measuring a skin spectrum with a colorimeter before and after the treatment on the skin subjected to the treatment for enhancing the whitening effect, and before and after the treatment of the skin site by the skin spectrum measurement. And calculating the whitening effect based on the increase rate of the average total hemoglobin content and determining the whitening effect based on the increase rate of the average total hemoglobin content.

  According to the above invention, for example, the skin spectrum is analyzed by a colorimeter with respect to the skin to which a whitening agent is applied or a cosmetic massage is performed, and the increase rate of the average total hemoglobin content in the measurement site is determined. The whitening effect can be evaluated.

  The invention described in claim 2 is characterized in that, in the method described in claim 1, the skin subjected to the treatment for enhancing the whitening effect is a forehead, a lower part of the eyes, and a cheek.

  According to the above-mentioned invention, for example, applying a whitening agent or applying a beauty massage, forehead, under the eyes and cheeks, the skin spectrum is analyzed by a colorimeter, and the average total hemoglobin content of the measurement site is increased. The whitening effect can be evaluated by judging the rate.

  The invention according to claim 3 is characterized in that, in the method according to claim 2, the increasing rate of the average total hemoglobin content is 10% or more and 20% or less.

  According to the above invention, for example, the skin spectrum is analyzed by a colorimeter with respect to skin to which a whitening agent is applied or cosmetic massage is performed, and the increase rate of the average total hemoglobin content in the measurement site is 10%. When it is 20% or less, it can be evaluated as an effective whitening effect.

According to the present invention, as an evaluation standard for the whitening effect, the decrease in melanin as a light absorber of the skin and the accompanying increase in the L ^* value (whiteness) of the L ^* a ^* b ^* color system The increase in the whiteness of the skin color caused by the skin color change due to blood circulation promotion can be applied to the evaluation of the whitening effect without depending on the blood circulation. That is, when evaluating the increase in the whiteness of the skin color, when the average total hemoglobin increase rate in the blood in the three parts of the forehead, under the eyes, and cheeks is 10% or more and 20% or less by analyzing the skin spectrum, It can be evaluated as having achieved a good whitening effect.

  Hereinafter, the present invention will be described in detail with reference to the accompanying drawings.

The method of evaluating the whitening effect of the present invention is based on the hypothesis that the skin with improved blood circulation looks healthy and white and has a favorable skin color. The skin color on chromatic measurement is black (L ^* a ^* b ^* color system, L ^* is low), but the skin color as a sensuous appearance is derived white, leading to a new whitening As an effect evaluation method, the present invention is characterized by a novel whitening effect evaluation by calculating the amount of hemoglobin by normal skin color measurement and analyzing the relationship between the change in the amount of hemoglobin and the appearance of the skin color. In the L ^* a ^* b ^* color system, the L ^* value indicates lightness (black and white). The smaller the value, the darker (black), the larger the value, the brighter (white), and the a ^* value and b ^* value. In the first quadrant, which is the color region to which the skin color belongs, a ^* indicates redness and b ^* indicates yellowness.

  Therefore, in a preferred embodiment of the present invention, a step of measuring the skin spectrum with a colorimeter before and after the treatment on the skin subjected to the treatment for enhancing the whitening effect, and an average total before and after the treatment of the skin part by the skin spectrum measurement. The skin whitening effect is evaluated by calculating the increase rate of the hemoglobin content and determining the whitening effect based on the increase rate of the average total hemoglobin content. More specifically, the skin spectrum of the three parts of the forehead, under the eyes, and cheeks is measured with a commercially available colorimeter (Konica Minolta CM2600d) (Japanese Patent Application No. 10-106517), and blood in those three parts is further measured. The amount of oxidized hemoglobin and the amount of reduced hemoglobin are measured, the total hemoglobin amount is calculated as the sum, and the whitening effect is evaluated by the increase rate of the average total hemoglobin amount.

  Thus, according to the present invention, it is possible to determine the average total hemoglobin amount in the blood at the three parts of the forehead, under the eyes, and cheeks, and the increase rate of the average total hemoglobin amount in the blood is 10% or more and 20% or less. In some cases, the whitening effect is good. When the increase rate of the average total hemoglobin amount in the blood of the part is lower than 10%, there is no whiteness of the skin color clearly from the lightness value by the skin spectrum analysis or the visual appearance of the skin. When the increase rate of the average total hemoglobin in the blood exceeds 20%, the face becomes reddish and the whitening effect is difficult to judge.

  Hereinafter, the present invention will be described in detail by way of examples.

  The present invention is described in detail below, but the present invention is not limited thereto.

Fig. 1 shows skin measurements before and after continuous use of a whitening agent (Shiseido White Lucent Serum Excellent: Shiseido Co., Ltd.) for 3 months for subjects who are worried about freckles (30 women). It is a figure which shows the skin color measurement value (L ^* a ^* b ^* ) and the amount of melanin and hemoglobin in Konica Minolta CM2600d). Based on the subject's self-evaluation and sensory evaluation based on the evaluation of a professional beauty technician, the skin color was evaluated in five levels (1: blackened, 2: slightly blackened, 3: no change, 4: slightly whitened, 5: Group that was judged to be effective (4: slightly whitened, 5: whitened), no effect (1: blackened, 2: slightly blackened, 3: no change) The groups determined as are shown on the right and left in each graph in the figure. In addition, the group with the effect of skin color is 20 out of 30 subjects. As shown in the figure, in the group in which the whitening effect was recognized, the L ^* value that is an index of skin brightness is generally not related to the whitening effect, while the decrease in the amount of melanin. In addition, an increase in the amount of hemoglobin in the blood, in particular, the amount of oxidized hemoglobin is observed.

  Therefore, before the continuous use of the whitening agent and after continuous use for 3 months, 1) a panel in which only the amount of melanin decreased, 2) a panel in which only the amount of hemoglobin increased, and 3) a panel in which the amount of melanin decreased and the amount of hemoglobin increased. Sensory evaluation of the skin color by the digital face image and the subject's own self-evaluation is shown in FIGS. From these figures, it was confirmed that the skin color change was 1) no change, 2) slightly white, and 3) white.

  Therefore, in the case where the whitening effect was felt by the skin color sensory evaluation based on the self-evaluation of the subject himself, an increase in the amount of oxyhemoglobin was recognized in addition to the decrease in the amount of melanin. From this, it can be seen that, in order to enhance the whiteness of the skin color, in addition to the suppression of melanin production by the whitening agent, the skin color change by promoting blood circulation is effective as a whitening effect. In other words, the whitening effect can be evaluated by measuring the blood circulation state of the skin.

  The effect of skin improvement with increased blood flow on the whitening effect was confirmed.

  In this embodiment, for example, facial massage such as general massage such as touch, massage, push, and tap on the skin and muscles of the face and neck and astringent lotion (Shiseido) By the improvement of blood flow by treatment with Elixir Conditioning Water), the skin color appearance and wrinkle conspicuousness when the skin color was good and healthy were confirmed by experiments on five panels.

  The skin before and after the treatment is self-evaluated by the panel and a visual engineer evaluates the skin, and the skin spectrum (skin color, melanin amount, hemoglobin amount) is measured by attaching the colorimeter head to the skin before and after the treatment. The skin surface temperature by thermography was measured by a method according to the above-mentioned photography, and further evaluated by digital face photography.

  FIG. 5 shows the items of the self-evaluation of the panel himself and the visual evaluation by the professional engineer and the stage of the evaluation scale.

  FIG. 6 shows changes in the amount of melanin and the amount of oxyhemoglobin before and after treatment with facial massage and astringent lotion for a panel of five people. As is clear from FIG. 6, no change was observed in the amount of melanin by facial massage and astringent lotion, but a significant increase was observed in the amount of oxyhemoglobin, confirming the effect of promoting blood circulation.

  Moreover, the average skin state change of the panel of five by facial massage and astringent lotion by the expert's visual evaluation is shown in FIG. According to the visual evaluation of a professional engineer, the blood circulation promotion effect was recognized as a skin blood circulation improvement effect and a gloss improvement effect, and was recognized as a slight effect as skin brightness, transparency, and pore suppression. Moreover, the average skin state change by the facial massage and the astringent lotion which the panel person self-evaluated in FIG. 8 is shown. Also in this case, the blood circulation promoting effect was recognized as various skin effects such as skin brightness, transparency, pores, and bears.

  In addition, in FIG. 9, by visual evaluation, a remarkable improvement was confirmed in skin whiteness and skin brightness, and an increase in oxygenated hemoglobin was recognized by the skin spectrum, and the skin surface temperature increased by thermography. The effect of the treatment comparing the digital face images before and after the treatment of the name panel is shown.

  Therefore, the blood circulation promotion effect was confirmed by the treatment with the facial massage and the astringent lotion, and it was confirmed that the blood circulation promotion was effective in the whitening effect. Moreover, not only the whitening effect but also skin improvement effects such as transparency, pores, and bears were recognized by promoting blood circulation.

  Therefore, when using a whitening agent, in addition to reducing the amount of melanin, a whitening effect is confirmed by promoting blood circulation by increasing the amount of hemoglobin, and when using facial massage and astringent lotion, Although there was no change, a remarkable whitening effect was confirmed by promoting blood circulation by increasing the amount of hemoglobin, and various skin improvement effects were confirmed.

  In addition, in the panel of 5 people who performed the treatment with facial massage and astringent lotion as described above, the panel itself self-evaluation before and after the treatment and the visual evaluation by 2 professional engineers, and the comprehensive results derived from those results The results of sensory evaluation are shown in Table 1. Note that the items of the self-evaluation of the panel person before and after the treatment in Table 1 and the visual evaluation items by the two specialists and the stage of the evaluation scale are different from the evaluation items and the stage of the evaluation scale shown in FIG. The sensory evaluation does not take into account the panel's self-assessment. If there is no negative value in the difference between the postoperative value derived from the visual evaluation by two specialist engineers and the preoperative value, a negative value If there is one, △ is indicated, and if there are two or more negative values, it is indicated as x.

In addition, in each panel of 5 patients after the treatment, the rate of increase of the post-treatment value with respect to the pre-treatment value of melanin, oxidized hemoglobin in the blood, reduced hemoglobin, and total hemoglobin amount changed for each forehead, under the eyes and cheeks. The results are shown in Table 2.

Further, for each panel, the amount of change in the amount of oxidized hemoglobin, reduced hemoglobin, and total hemoglobin in the average blood of the results in Table 2 and under the eyes and cheeks is shown in Table 3.

From this result, in the panel in which the change rate of the average total hemoglobin amount at the three parts of the forehead, under the eyes, and cheeks was 10% or more, good results were obtained for the whitening effect even in the sensory evaluation of Table 1. FIG. 12 shows the relationship between the rate of change in the average total hemoglobin amount at the forehead of the panels 1 to 5 according to Table 3, the three parts of the lower part of the eye, and the cheek, and the sensory comprehensive determination according to Table 1.

  As comparative examples, FIGS. 10 and 11 show digital face photographs in which the change rates of the average total hemoglobin amount at the three parts of the forehead, under the eyes, and cheeks are 22.3% and 43.2%, respectively. As can be seen, when the rate of change in the average total hemoglobin amount at the three parts of the forehead, under the eyes, and cheeks exceeds 20%, the face becomes reddish and the whitening effect by promoting blood circulation becomes difficult.

  Therefore, a good whitening effect was observed when the change rate of the average total hemoglobin amount at the three parts of the forehead, under the eyes, and cheeks was 10% or more and 20% or less.

From these results, the evaluation standard of the whitening effect depends on the decrease of melanin as a light absorber of skin and the accompanying increase in L ^* (whiteness) of L ^* a ^* b ^* color system. The increase in the whiteness of the skin color caused by the skin color change due to blood circulation promotion can be applied to the evaluation of the whitening effect.

  Therefore, the method for evaluating the whitening effect of the present invention takes into account the effectiveness of promoting blood circulation, and the whiteness of the skin is measured by measuring the change in the amount of hemoglobin in the blood at the site where the whiteness of the skin is measured. The increase in feeling can be evaluated.

  The preferred embodiments of the present invention have been described in detail above, but the present invention is not limited to such specific embodiments, and various modifications and changes can be made within the scope of the gist of the present invention described in the claims. It can be changed.

Figure showing skin colorimetric values (L ^* a ^* b ^* ) and melanin / hemoglobin levels in skin measurements before and after continuous use of a whitening agent over a period of 3 months for subjects concerned with freckles It is. It is a figure which shows the sensory evaluation of the skin color by 1) the digital face image of the panel in which only the amount of melanin decreased, and the subject's own self-evaluation before continuous use of the whitening agent and after continuous use for 3 months. It is a figure which shows the sensory evaluation of the skin color by 2) the digital face image of the panel in which only the amount of hemoglobin increased, and the test subject's own self-evaluation before continuous use of a whitening agent, and after continuous use for 3 months. It is a figure which shows the sensory evaluation of the skin color by the digital face image of the panel where the amount of melanin decreased and the amount of hemoglobin increased, and the subject's own self-evaluation before continuous use of the whitening agent and after continuous use for 3 months. It is a figure which shows the stage of the self-evaluation of a panel person, the item of visual evaluation by a professional engineer, and an evaluation scale. It is a figure which shows the change of the melanin amount before and behind the treatment by a facial massage and an astringent lotion, and the amount of oxyhemoglobin. It is a figure which shows the average skin state change of five panels by the facial massage and astringent lotion by the visual evaluation of a professional engineer. It is a figure which shows the average skin state change by the facial massage and the astringent lotion self-evaluated by the panel person. Visual evaluation confirmed a marked improvement in skin whiteness and skin brightness, skin spectrum showed an increase in oxyhemoglobin, and thermography increased skin surface temperature before treatment for one panel. It is a figure which shows an example of the treatment effect which compared the digital face image after. It is a face photograph in which the change rate of the average total hemoglobin amount in the three parts of the forehead, under the eyes, and cheeks exceeds 20%. It is a face photograph in which the change rate of the average total hemoglobin amount in the three parts of the forehead, under the eyes, and cheeks exceeds 20%. FIG. 5 is a diagram showing the relationship between the change rate of the average total hemoglobin amount at the three foreheads of the panels 1 to 5 according to Table 3 and under the eyes and cheeks and the sensory comprehensive determination according to Table 1.

Claims (3)

Measuring the skin spectrum with a colorimeter before and after the treatment on the skin subjected to the treatment for enhancing the whitening effect;
Calculating the rate of increase in average total hemoglobin content before and after treatment of the skin site by the skin spectrum measurement;
A method of evaluating a whitening effect, comprising: determining a whitening effect based on an increase rate of the average total hemoglobin content.   The method according to claim 1, wherein the skin subjected to the treatment for enhancing the whitening effect is a forehead, an eye and a cheek.   The method according to claim 1 or 2, wherein an increase rate of the average total hemoglobin content is 10% or more and 20% or less.