JP2007284424A5 - - Google Patents
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- Publication number
- JP2007284424A5 JP2007284424A5 JP2007061438A JP2007061438A JP2007284424A5 JP 2007284424 A5 JP2007284424 A5 JP 2007284424A5 JP 2007061438 A JP2007061438 A JP 2007061438A JP 2007061438 A JP2007061438 A JP 2007061438A JP 2007284424 A5 JP2007284424 A5 JP 2007284424A5
- Authority
- JP
- Japan
- Prior art keywords
- blood
- increase
- pharmaceutical composition
- loxoprofen
- nitric oxide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000008280 blood Substances 0.000 claims 10
- 210000004369 blood Anatomy 0.000 claims 10
- MWUXSHHQAYIFBG-UHFFFAOYSA-N Nitric oxide Chemical compound O=[N] MWUXSHHQAYIFBG-UHFFFAOYSA-N 0.000 claims 8
- 239000008194 pharmaceutical composition Substances 0.000 claims 7
- 239000003963 antioxidant agent Substances 0.000 claims 6
- 208000024172 Cardiovascular disease Diseases 0.000 claims 5
- YMBXTVYHTMGZDW-UHFFFAOYSA-N loxoprofen Chemical compound C1=CC(C(C(O)=O)C)=CC=C1CC1C(=O)CCC1 YMBXTVYHTMGZDW-UHFFFAOYSA-N 0.000 claims 5
- 229960002373 loxoprofen Drugs 0.000 claims 5
- 230000000694 effects Effects 0.000 claims 4
- 230000003511 endothelial effect Effects 0.000 claims 4
- 102000004190 Enzymes Human genes 0.000 claims 2
- 108090000790 Enzymes Proteins 0.000 claims 2
- 102000019197 Superoxide Dismutase Human genes 0.000 claims 2
- 108010012715 Superoxide dismutase Proteins 0.000 claims 2
- 230000003078 antioxidant effect Effects 0.000 claims 2
- 230000015572 biosynthetic process Effects 0.000 claims 2
- 230000036765 blood level Effects 0.000 claims 2
- 230000003247 decreasing effect Effects 0.000 claims 2
- 201000010099 disease Diseases 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 150000002632 lipids Chemical class 0.000 claims 2
- 238000003786 synthesis reaction Methods 0.000 claims 2
- 150000003626 triacylglycerols Chemical class 0.000 claims 2
- 230000002792 vascular Effects 0.000 claims 2
- 208000031226 Hyperlipidaemia Diseases 0.000 claims 1
- 208000007536 Thrombosis Diseases 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2007061438A JP5171073B2 (ja) | 2006-03-23 | 2007-03-12 | 循環器系疾患の予防又は治療のための医薬組成物 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2006081486 | 2006-03-23 | ||
| JP2006081486 | 2006-03-23 | ||
| JP2007061438A JP5171073B2 (ja) | 2006-03-23 | 2007-03-12 | 循環器系疾患の予防又は治療のための医薬組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2007284424A JP2007284424A (ja) | 2007-11-01 |
| JP2007284424A5 true JP2007284424A5 (enrdf_load_stackoverflow) | 2010-03-25 |
| JP5171073B2 JP5171073B2 (ja) | 2013-03-27 |
Family
ID=38756530
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007061438A Expired - Fee Related JP5171073B2 (ja) | 2006-03-23 | 2007-03-12 | 循環器系疾患の予防又は治療のための医薬組成物 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP5171073B2 (enrdf_load_stackoverflow) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008031164A (ja) * | 2006-07-07 | 2008-02-14 | Daiichi Sankyo Healthcare Co Ltd | 高尿酸血症又はこれに起因する疾患の予防又は治療のための医薬組成物 |
-
2007
- 2007-03-12 JP JP2007061438A patent/JP5171073B2/ja not_active Expired - Fee Related
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