JP2006520610A5 - - Google Patents
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- Publication number
- JP2006520610A5 JP2006520610A5 JP2006509121A JP2006509121A JP2006520610A5 JP 2006520610 A5 JP2006520610 A5 JP 2006520610A5 JP 2006509121 A JP2006509121 A JP 2006509121A JP 2006509121 A JP2006509121 A JP 2006509121A JP 2006520610 A5 JP2006520610 A5 JP 2006520610A5
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US45182003P | 2003-03-04 | 2003-03-04 | |
| PCT/US2004/006571 WO2004078937A2 (en) | 2003-03-04 | 2004-03-04 | Vectors used to create hybrid constant regions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006520610A JP2006520610A (ja) | 2006-09-14 |
| JP2006520610A5 true JP2006520610A5 (enExample) | 2007-01-11 |
Family
ID=32962642
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006509121A Pending JP2006520610A (ja) | 2003-03-04 | 2004-03-04 | ハイブリッド不変領域を産生するのに用いるベクター |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20070009957A1 (enExample) |
| EP (1) | EP1606387A4 (enExample) |
| JP (1) | JP2006520610A (enExample) |
| AU (1) | AU2004217433A1 (enExample) |
| CA (1) | CA2517519A1 (enExample) |
| WO (1) | WO2004078937A2 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060057651A1 (en) | 2000-12-08 | 2006-03-16 | Bowdish Katherine S | Polypeptides and antibodies derived from chronic lymphocytic leukemia cells and uses thereof |
| US7427665B2 (en) | 2000-12-08 | 2008-09-23 | Alexion Pharmaceuticals, Inc. | Chronic lymphocytic leukemia cell line |
| US9249229B2 (en) | 2000-12-08 | 2016-02-02 | Alexion Pharmaceuticals, Inc. | Polypeptides and antibodies derived from chronic lymphocytic leukemia cells and uses thereof |
| US7408041B2 (en) | 2000-12-08 | 2008-08-05 | Alexion Pharmaceuticals, Inc. | Polypeptides and antibodies derived from chronic lymphocytic leukemia cells and uses thereof |
| US6803230B2 (en) | 2001-04-27 | 2004-10-12 | Alexion Pharmaceuticals, Inc. | Phagemid vectors |
| US8075884B2 (en) | 2006-01-12 | 2011-12-13 | Alexion Pharmaceuticals, Inc. | Antibodies to OX-2/CD200 and uses thereof |
| US8986684B2 (en) | 2007-07-25 | 2015-03-24 | Alexion Pharmaceuticals, Inc. | Methods and compositions for treating autoimmune disease |
| US20110059471A1 (en) * | 2008-03-14 | 2011-03-10 | Medinet Co., Ltd. | Antibody having an immune-enhancement function |
| WO2010039900A2 (en) * | 2008-09-30 | 2010-04-08 | Aliva Biopharmaceuticals, Inc. | Non-human mammals for the production of chimeric antibodies |
| HRP20151188T4 (hr) | 2010-02-08 | 2021-10-01 | Regeneron Pharmaceuticals, Inc. | Miš sa zajedničkim lakim lancem |
| US9796788B2 (en) | 2010-02-08 | 2017-10-24 | Regeneron Pharmaceuticals, Inc. | Mice expressing a limited immunoglobulin light chain repertoire |
| US20130045492A1 (en) | 2010-02-08 | 2013-02-21 | Regeneron Pharmaceuticals, Inc. | Methods For Making Fully Human Bispecific Antibodies Using A Common Light Chain |
| PL3251503T3 (pl) | 2010-03-31 | 2024-07-08 | Ablexis, Llc | Modyfikacja myszy metodami inżynierii genetycznej w celu wytworzenia przeciwciał chimerycznych |
| PT3865581T (pt) | 2011-08-05 | 2024-10-04 | Regeneron Pharma | Murganhos da cadeia leve universal humanizada |
| CN106255410B (zh) | 2014-03-21 | 2020-01-10 | 瑞泽恩制药公司 | 产生单结构域结合蛋白的非人动物 |
| US11111314B2 (en) | 2015-03-19 | 2021-09-07 | Regeneron Pharmaceuticals, Inc. | Non-human animals that select for light chain variable regions that bind antigen |
| US11761963B2 (en) | 2017-09-27 | 2023-09-19 | Alexion Pharmaceuticals, Inc. | Biomarker signature for predicting tumor response to anti-CD200 therapy |
| JP7627413B2 (ja) * | 2020-08-21 | 2025-02-06 | ファチアブジェン インコーポレイテッド | ガンマ定常領域(Cγ1)とイプシロン定常領域(Cε2-4)とが融合された重鎖及び軽鎖の定常領域からなる抗体断片及びその用途 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5618920A (en) * | 1985-11-01 | 1997-04-08 | Xoma Corporation | Modular assembly of antibody genes, antibodies prepared thereby and use |
| US7119248B1 (en) * | 1994-04-12 | 2006-10-10 | Miltenyi Biotec Gmbh | Antibodies against epitopes with homology to self antigens, methods of preparation and applications thereof |
| US6258529B1 (en) * | 1994-12-01 | 2001-07-10 | Oravax, Inc. | PCR amplification of rearranged genomic variable regions of immunoglobulin genes |
| WO1997042329A1 (en) * | 1996-05-04 | 1997-11-13 | Zeneca Limited | Monoclonal antibody to cea, conjugates comprising said antibody, and their therapeutic use in an adept system |
| IL155977A0 (en) * | 2000-11-30 | 2003-12-23 | Medarex Inc | Transgenic transchromosomal rodents for making human antibodies |
| EP2339035A1 (en) * | 2000-12-07 | 2011-06-29 | Novartis Vaccines and Diagnostics, Inc. | Endogenous retroviruses up-regulated in prostate cancer |
| US6803230B2 (en) * | 2001-04-27 | 2004-10-12 | Alexion Pharmaceuticals, Inc. | Phagemid vectors |
| DE60226253T2 (de) * | 2001-06-28 | 2009-05-14 | Kyowa Hakko Kogyo Co., Ltd. | Humanisierter antikörper gegen fibroblastenwachstumsfaktor 8 und fragment des antikörpers |
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2004
- 2004-03-04 CA CA002517519A patent/CA2517519A1/en not_active Abandoned
- 2004-03-04 WO PCT/US2004/006571 patent/WO2004078937A2/en not_active Ceased
- 2004-03-04 AU AU2004217433A patent/AU2004217433A1/en not_active Abandoned
- 2004-03-04 EP EP04717390A patent/EP1606387A4/en not_active Withdrawn
- 2004-03-04 JP JP2006509121A patent/JP2006520610A/ja active Pending
- 2004-03-04 US US10/547,275 patent/US20070009957A1/en not_active Abandoned