JP2006520317A5 - - Google Patents

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JP2006520317A5
JP2006520317A5 JP2004543323A JP2004543323A JP2006520317A5 JP 2006520317 A5 JP2006520317 A5 JP 2006520317A5 JP 2004543323 A JP2004543323 A JP 2004543323A JP 2004543323 A JP2004543323 A JP 2004543323A JP 2006520317 A5 JP2006520317 A5 JP 2006520317A5
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protein
peptide
magnetic material
synthetic peptide
synthetic
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JP2004543323A
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JP2006520317A (en
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Priority claimed from PCT/US2003/029555 external-priority patent/WO2004033488A2/en
Publication of JP2006520317A publication Critical patent/JP2006520317A/en
Publication of JP2006520317A5 publication Critical patent/JP2006520317A5/ja
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Claims (26)

以下の工程を含む、磁性材料を製造する方法：
磁性材料の表面に特異的に結合する部分を含む合成ペプチドまたは合成タンパク質を提供する工程；
1種以上の磁性材料前駆物質を、磁性材料が形成されるような条件で、合成ペプチドまたは合成タンパク質と接触させる工程。 A method for producing a magnetic material comprising the following steps:
Providing a synthetic peptide or protein comprising a moiety that specifically binds to the surface of the magnetic material;
Contacting one or more magnetic material precursors with a synthetic peptide or protein under conditions such that the magnetic material is formed. 合成ペプチドまたは合成タンパク質を基板に結合させる工程をさらに含む、請求項1記載の方法。 2. The method of claim 1 , further comprising attaching a synthetic peptide or synthetic protein to the substrate. 合成ペプチドまたは合成タンパク質がコンビナトリアル・ライブラリーのスクリーニングによって選択される、請求項1または2記載の方法。 The method according to claim 1 or 2 , wherein the synthetic peptide or protein is selected by screening a combinatorial library. 磁性材料を単離する工程をさらに含む、請求項1または2記載の方法。 The method according to claim 1 or 2 , further comprising the step of isolating the magnetic material. ペプチドまたはタンパク質が自己組立性分子の一部を含む、請求項1または2記載の方法。 The method according to claim 1 or 2 , wherein the peptide or protein comprises a part of a self-assembling molecule. 自己組立性分子がファージである、請求項5記載の方法。 6. The method of claim 5 , wherein the self-assembling molecule is a phage. 磁性材料がナノ粒子である、請求項1または2記載の方法。 The method according to claim 1 or 2 , wherein the magnetic material is nanoparticles. 合成ペプチドまたは合成タンパク質がキメラタンパク質の一部を含む、請求項1または2記載の方法。 The method according to claim 1 or 2 , wherein the synthetic peptide or protein comprises a part of a chimeric protein. 結合性のペプチドまたはタンパク質と、１種以上の磁性材料前駆物質を使用することによって形成される磁性材料。 A magnetic material formed by using a binding peptide or protein and one or more magnetic material precursors. ペプチドまたはタンパク質を、金属塩および還元剤の存在下で使用する、請求項9記載の磁性材料。 10. The magnetic material according to claim 9 , wherein the peptide or protein is used in the presence of a metal salt and a reducing agent. ナノ粒子を含む、請求項9または10の磁性材料。 11. A magnetic material according to claim 9 or 10 comprising nanoparticles. ε-Coに特異的に結合するペプチドを含む組成物。   A composition comprising a peptide that specifically binds to ε-Co. CoPtに特異的に結合するペプチドを含む組成物。   A composition comprising a peptide that specifically binds to CoPt. FePtに特異的に結合するペプチドを含む組成物。   A composition comprising a peptide that specifically binds to FePt. SmCo5に特異的に結合するペプチドを含む組成物。 Composition comprising a peptide that specifically binds to SmCo 5. 強磁性表面に特異的に結合するペプチドを含む組成物。   A composition comprising a peptide that specifically binds to a ferromagnetic surface. 以下の工程を含む、磁性材料に特異的に結合する合成ペプチドまたは合成タンパク質を単離する方法：
合成ペプチドまたは合成タンパク質のライブラリーを、磁性材料と接触させる工程；
非結合の合成ペプチドまたは合成タンパク質をライブラリーから除去する工程；および
結合した合成ペプチドまたは合成タンパク質を磁性材料から溶離させる工程。 A method of isolating a synthetic peptide or protein that specifically binds to a magnetic material, comprising the following steps:
Contacting a library of synthetic peptides or proteins with a magnetic material;
Removing unbound synthetic peptide or protein from the library; and eluting the bound synthetic peptide or protein from the magnetic material. 合成ペプチドまたは合成タンパク質のライブラリーが、ファージ・ディスプレー・ライブラリーを含むものであるとしてさらに定義される、請求項17記載の方法。 18. The method of claim 17 , wherein the synthetic peptide or protein library is further defined as comprising a phage display library. 合成ペプチドまたは合成タンパク質のライブラリーが、コンビナトリアル・ケミストリー・ライブラリーを含むものであるとしてさらに定義される、請求項17記載の方法。 18. The method of claim 17 , wherein the synthetic peptide or protein library is further defined as comprising a combinatorial chemistry library. 以下の工程を含む、粒子フィルムを調製する方法：
粒子の溶液を表面に加え、その際に、結合性の合成ペプチドまたは合成タンパク質を使用することによって粒子を合成する工程；
ナノ粒子の溶液を表面上で蒸発させる工程；および
粒子を表面にアニーリングして、粒子のフィルムを創出する工程。 A method of preparing a particle film comprising the following steps:
Adding a solution of particles to the surface, wherein the particles are synthesized by using binding synthetic peptides or proteins ;
Evaporating a solution of nanoparticles on the surface; and annealing the particles to the surface to create a film of particles. 粒子がナノ粒子である、請求項20記載の方法。 21. The method of claim 20 , wherein the particles are nanoparticles. 以下の工程を含む、金属材料の製造方法：
金属表面に特異的に結合する部分を含む合成ペプチドまたは合成タンパク質を提供する工程；
1種以上の金属材料前駆物質を、金属材料が形成されるような条件で、合成ペプチドと接触させる工程。 A method for producing a metal material including the following steps:
Providing a synthetic peptide or protein comprising a moiety that specifically binds to a metal surface;
Contacting one or more metal material precursors with a synthetic peptide under conditions such that a metal material is formed; 300℃以下の温度で接触が行われる、請求項1記載の方法。 The method of claim 1, wherein the contacting is performed at a temperature of 300 ° C. or less. 300℃以下の温度で接触が行われる、請求項22記載の方法。 23. The method of claim 22, wherein the contacting is performed at a temperature of 300 ° C or lower. 結合性の合成ペプチドによって合成したまたは合成タンパク質によって合成した金属粒子を含む金属材料。 A metal material comprising metal particles synthesized by a binding synthetic peptide or synthesized by a synthetic protein . 結合性の合成ペプチドによって合成したまたは合成タンパク質によって合成した金属ナノ粒子の集まりを含んでおり、金属ナノ粒子は、多結晶材料から単結晶材料へとアニーリングされている、金属材料。 A metal material comprising a collection of metal nanoparticles synthesized by a binding synthetic peptide or synthesized by a synthetic protein , wherein the metal nanoparticles are annealed from a polycrystalline material to a single crystal material.
JP2004543323A 2002-09-18 2003-09-22 Peptide-mediated synthesis of metal and magnetic materials Pending JP2006520317A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US41180402P 2002-09-18 2002-09-18
PCT/US2003/029555 WO2004033488A2 (en) 2002-09-18 2003-09-22 Peptide mediated synthesis of metallic and magnetic materials

Publications (2)

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JP2006520317A JP2006520317A (en) 2006-09-07
JP2006520317A5 true JP2006520317A5 (en) 2006-11-16

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EP (1) EP1539342A2 (en)
JP (1) JP2006520317A (en)
KR (1) KR20050043973A (en)
CN (1) CN1753724A (en)
AU (1) AU2003298587A1 (en)
CA (1) CA2499318A1 (en)
WO (1) WO2004033488A2 (en)

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