JP2006516651A5 - - Google Patents
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- Publication number
- JP2006516651A5 JP2006516651A5 JP2006503313A JP2006503313A JP2006516651A5 JP 2006516651 A5 JP2006516651 A5 JP 2006516651A5 JP 2006503313 A JP2006503313 A JP 2006503313A JP 2006503313 A JP2006503313 A JP 2006503313A JP 2006516651 A5 JP2006516651 A5 JP 2006516651A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- glucocorticoid receptor
- receptor antagonist
- psychosis
- kit
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 claims 16
- 239000003850 glucocorticoid receptor antagonist Substances 0.000 claims 8
- 229940126013 glucocorticoid receptor antagonist Drugs 0.000 claims 7
- 208000028017 Psychotic disease Diseases 0.000 claims 6
- 208000024891 symptom Diseases 0.000 claims 4
- 230000035606 childbirth Effects 0.000 claims 3
- VKHAHZOOUSRJNA-GCNJZUOMSA-N mifepristone Chemical compound C1([C@@H]2C3=C4CCC(=O)C=C4CC[C@H]3[C@@H]3CC[C@@]([C@]3(C2)C)(O)C#CC)=CC=C(N(C)C)C=C1 VKHAHZOOUSRJNA-GCNJZUOMSA-N 0.000 claims 3
- 229960003248 mifepristone Drugs 0.000 claims 3
- 208000021011 postpartum psychosis Diseases 0.000 claims 3
- 150000003431 steroids Chemical group 0.000 claims 3
- -1 dimethylaminophenyl moiety Chemical group 0.000 claims 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 2
- YWROELXZPBSUCO-IYXRBSQSSA-N (2r)-1,2,3,4,4a,4b,5,6-octahydrophenanthrene-2,7-diol Chemical compound C12CCC(O)=CC2=CC=C2C1CC[C@@H](O)C2 YWROELXZPBSUCO-IYXRBSQSSA-N 0.000 claims 1
- ZCAUIZYRNPHJJO-CAMMJAKZSA-N (8s,10s,13s,14s)-10,13-dimethyl-1,2,6,7,8,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-one Chemical compound C([C@H]12)CC3=CC(=O)CC[C@]3(C)C1=CC[C@@]1(C)[C@H]2CCC1 ZCAUIZYRNPHJJO-CAMMJAKZSA-N 0.000 claims 1
- 125000000530 1-propynyl group Chemical group [H]C([H])([H])C#C* 0.000 claims 1
- 125000000590 4-methylphenyl group Chemical group [H]C1=C([H])C(=C([H])C([H])=C1*)C([H])([H])[H] 0.000 claims 1
- 102000003676 Glucocorticoid Receptors Human genes 0.000 claims 1
- 108090000079 Glucocorticoid Receptors Proteins 0.000 claims 1
- 239000000443 aerosol Substances 0.000 claims 1
- 239000005557 antagonist Substances 0.000 claims 1
- 239000007921 spray Substances 0.000 claims 1
- 239000000725 suspension Substances 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US44528403P | 2003-02-04 | 2003-02-04 | |
| PCT/US2004/003183 WO2004069202A2 (en) | 2003-02-04 | 2004-02-04 | Antiglucocorticoids for the treatment of postpartum psychosis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006516651A JP2006516651A (ja) | 2006-07-06 |
| JP2006516651A5 true JP2006516651A5 (https=) | 2007-03-15 |
Family
ID=32850982
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006503313A Pending JP2006516651A (ja) | 2003-02-04 | 2004-02-04 | 産後精神病の処置のための抗糖質コルチコイド |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20040229855A1 (https=) |
| EP (1) | EP1599208A4 (https=) |
| JP (1) | JP2006516651A (https=) |
| AU (1) | AU2004208842B2 (https=) |
| CA (1) | CA2514966A1 (https=) |
| WO (1) | WO2004069202A2 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HRP20110702T1 (hr) | 2007-02-02 | 2011-10-31 | Pfizer Products Inc. | Triciklički spojevi i njihova uporaba kao modulatora glukokortikoidnih receptora |
| AU2009267016B2 (en) * | 2008-07-01 | 2014-07-03 | Corcept Therapeutics, Inc. | Use of mifepristone for the treatment of Amyotrophic Lateral Sclerosis |
| US10500216B2 (en) | 2011-11-18 | 2019-12-10 | Corcept Therapeutics, Inc. | Optimizing mifepristone absorption |
| US8859774B2 (en) | 2012-05-25 | 2014-10-14 | Corcept Therapeutics, Inc. | Heteroaryl-ketone fused azadecalin glucocorticoid receptor modulators |
| US12226412B2 (en) | 2012-05-25 | 2025-02-18 | Corcept Therapeutics, Inc. | Heteroaryl-ketone fused azadecalin glucocorticoid receptor modulators |
| US9943526B2 (en) | 2015-04-21 | 2018-04-17 | Corcept Therapeutics, Inc. | Optimizing mifepristone levels for cushing's patients |
| FI3897589T3 (fi) | 2018-12-19 | 2026-01-13 | Corcept Therapeutics Inc | Farmaseuttisia formulaatioita, jotka sisältävät relakorilanttia, heteroaryyliketonifusoitua atsekaliiniyhdistettä |
| US11285145B2 (en) | 2020-05-27 | 2022-03-29 | Corcept Therapeutics Incorporated | Concomitant administration of glucocorticoid receptor modulator relacorilant and paclitaxel, a dual substrate of CYP2C8 and CYP3A4 |
| WO2022134033A1 (en) | 2020-12-25 | 2022-06-30 | Corcept Therapeutics Incorporated | Methods of preparing heteroaryl-ketone fused azadecalin glucocorticoid receptor modulators |
| IL319657A (en) | 2022-10-06 | 2025-05-01 | Corcept Therapeutics Inc | Glucocorticoid receptor modulator formulations |
| WO2024092195A1 (en) | 2022-10-28 | 2024-05-02 | Corcept Therapeutics Incorporated | Treatments for amyotrophic lateral sclerosis using dazucorilant |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5468741A (en) * | 1993-05-28 | 1995-11-21 | The Regents Of The University Of California | Use of low levels of mifepristone to treat leiomyomata |
| IL118974A (en) * | 1995-08-17 | 2001-09-13 | Akzo Nobel Nv | History 11 - (Transformed Phenyl) - Astra - 4, 9 - Diane, their preparation and pharmaceutical preparations containing them |
| ATE332696T1 (de) * | 1997-10-06 | 2006-08-15 | Univ Leland Stanford Junior | Methode zur behandlung von durch glycocorticoidstörungen verursachten psychosen |
-
2004
- 2004-02-04 EP EP04708184A patent/EP1599208A4/en not_active Withdrawn
- 2004-02-04 JP JP2006503313A patent/JP2006516651A/ja active Pending
- 2004-02-04 AU AU2004208842A patent/AU2004208842B2/en not_active Ceased
- 2004-02-04 WO PCT/US2004/003183 patent/WO2004069202A2/en not_active Ceased
- 2004-02-04 CA CA002514966A patent/CA2514966A1/en not_active Abandoned
- 2004-02-04 US US10/772,919 patent/US20040229855A1/en not_active Abandoned
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