JP2006333751A - Potassium absorption inhibitor for food and food containing the same - Google Patents
Potassium absorption inhibitor for food and food containing the same Download PDFInfo
- Publication number
- JP2006333751A JP2006333751A JP2005160885A JP2005160885A JP2006333751A JP 2006333751 A JP2006333751 A JP 2006333751A JP 2005160885 A JP2005160885 A JP 2005160885A JP 2005160885 A JP2005160885 A JP 2005160885A JP 2006333751 A JP2006333751 A JP 2006333751A
- Authority
- JP
- Japan
- Prior art keywords
- food
- potassium ion
- potassium
- absorption inhibitor
- polysaccharide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Jellies, Jams, And Syrups (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Description
本発明は、食品として摂取されるカリウムイオンが、体内へ吸収されるのを抑制可能であるとともに、食品に添加することが可能な食品用カリウム吸収抑制剤及びそれが含まれた食品に関する。 The present invention relates to a potassium absorption inhibitor for foods that can suppress the absorption of potassium ions taken as food into the body and can be added to foods, and a food containing the same.
腎臓疾患である急性腎炎や慢性腎炎は、腎臓の糸球体の炎症により、むくみ・血尿やたんぱく尿としての異常・高血圧などの症状としてあらわれる病気である。症状が進むと腎臓機能が極端に低下して腎不全、尿毒症などを引き起こし、日常生活に大変な負担を与える人工透析や腎臓移植が必要となる。近年の生活習慣病である糖尿病が進行した糖尿病性腎症の患者数は、増加傾向にある。血液中の電解質成分は、腎臓機能の低下により異常をきたし、カリウムの排泄機能低下は、高カリウム血症をもたらす。そこで、このような腎臓疾患を有する者は、日常生活の中で食品中における１日のカリウムイオンの摂取量が制限されている。 Acute nephritis and chronic nephritis, which are kidney diseases, are diseases that appear as symptoms such as swelling, hematuria, abnormalities as proteinuria, and hypertension due to inflammation of the glomeruli of the kidney. As the symptoms progress, kidney function is extremely reduced, causing renal failure, uremia, etc., and artificial dialysis and kidney transplantation that give a heavy burden to daily life are necessary. The number of patients with diabetic nephropathy in which diabetes, which is a lifestyle-related disease in recent years, has been increasing. The electrolyte component in the blood is abnormal due to a decrease in kidney function, and a decrease in potassium excretion function results in hyperkalemia. Therefore, a person with such a kidney disease has a limited daily intake of potassium ions in food in daily life.
このようにカリウムの摂取量が制限されている患者は、食品として摂取されたカリウムを排泄する必要がある。摂取されたカリウムを排泄する腎臓疾患の医薬品として、カリウムを吸着する機能を有する陽イオン交換樹脂からなる経口投与剤などがあり、これによりカリウムが体内に吸収される量を制限することができる。 Thus, a patient whose potassium intake is limited needs to excrete potassium taken as food. As a medicine for kidney disease that excretes ingested potassium, there is an orally administered agent composed of a cation exchange resin having a function of adsorbing potassium, and this can limit the amount of potassium absorbed in the body.
一方、医薬品としてでなく食品として、カリウム濃度を低減させたり、またカリウムが体内に吸収されるのを抑制する方法が考案されている。例えば、特許文献１には、イオン交換による脱塩により摂取前の原料飲料のカリウム濃度を低減させる方法が記載されており、特許文献２には、ポリアニオンを含有し、カリウムイオンの体内への吸収を抑制させることを特徴とする食品が記載されている。 On the other hand, a method has been devised that reduces potassium concentration and suppresses absorption of potassium into the body as a food, not as a medicine. For example, Patent Literature 1 describes a method of reducing the potassium concentration of a raw beverage before ingestion by desalting by ion exchange, and Patent Literature 2 contains a polyanion and absorbs potassium ions into the body. A food product characterized by suppressing the above is described.
しかしながら、特許文献１に記載された方法は、食品飲料など液体にしか適用できず、また風味、香味などが壊されて商品価値を著しく低減するなどの問題がある。また、特許文献２に記載された食品は、生体内で消化器官中の胃酸や消化酵素などにより天然由来のポリアニオンが加水分解されるので、ポリアニオン自体が部分吸収されることがある。このポリアニオンの部分吸収により、補足したカリウムイオンは、再度離されて体内に吸収されることになるという問題がある。 However, the method described in Patent Document 1 can be applied only to liquids such as food and beverages, and there is a problem that flavor, flavor, and the like are broken to significantly reduce the commercial value. Moreover, since the naturally-derived polyanion is hydrolyzed in the living body by the stomach acid, digestive enzyme, etc. in a digestive organ in the foodstuff described in patent document 2, the polyanion itself may be partially absorbed. Due to partial absorption of this polyanion, the supplemented potassium ions are separated again and absorbed into the body.
そこで、本発明は、様々な食品形態にその食品の風味、香味などに影響を与えずに添加することが可能であるとともに、そのもの自体が部分吸収することが少ない食品用カリウム吸収抑制剤及びそれが含まれた食品を提供することを目的とする。 Accordingly, the present invention provides a potassium absorption inhibitor for foods that can be added to various food forms without affecting the flavor, flavor, etc. of the food, and that is itself less partially absorbed. The purpose is to provide foods containing.
以上の目的を達成するため、本発明者らは、鋭意研究を重ねた結果、カリウムイオン交換能を有する食品用多糖類からなるカリウムイオン交換多糖類を三次元網目構造の食品用高分子の三次元網目構造内に保持させるとともに、三次元網目構造内にカリウムイオンを透過させることにより、カリウムイオンをイオン交換により吸着させ体内へのカリウムの吸収を抑制することができることを見出した。すなわち、本発明は、カリウムイオン交換能を有する食品用多糖類からなるカリウムイオン交換多糖類と、三次元網目構造の食品用高分子からなり、その三次元網目構造内に前記カリウムイオン交換多糖類を保持するとともに、三次元網目構造内にカリウムイオンを透過可能な三次元高分子と、を備えたことを特徴とする食品用カリウムイオン吸収抑制剤である。また、本発明は、このような食品用カリウムイオン吸収抑制剤が含まれたことを特徴とする食品である。 In order to achieve the above object, the present inventors have conducted extensive research, and as a result, a potassium ion-exchange polysaccharide comprising a food-use polysaccharide having a potassium ion exchange ability is converted into a three-dimensional network structure of a food polymer. It has been found that by maintaining the original network structure and allowing potassium ions to permeate through the three-dimensional network structure, the potassium ions can be adsorbed by ion exchange and the absorption of potassium into the body can be suppressed. That is, the present invention comprises a potassium ion exchange polysaccharide comprising a food grade polysaccharide having potassium ion exchange capacity and a food polymer having a three-dimensional network structure, and the potassium ion exchange polysaccharide is contained in the three-dimensional network structure. And a three-dimensional polymer that can permeate potassium ions in a three-dimensional network structure, and a food-use potassium ion absorption inhibitor. Moreover, this invention is a foodstuff characterized by including such a food-grade potassium ion absorption inhibitor.
以上のように、本発明に係る食品用カリウムイオン吸収抑制剤において、カリウムイオン交換多糖類は、三次元高分子内に保持されているので、加水分解され難く、それ自体が吸収されることを防止することができる。すなわち、カリウムイオン交換能多糖類は、天然物であるため、化学合成されたイオン交換樹脂と異なり、消化管内の胃酸や酵素、腸内細菌などにより、分解されやすく、カリウム吸着能を低下させてしまう。これを防ぐため、本発明は、三次元高分子にカリウムイオン交換多糖類を包み込むことにより、カリウムイオン交換多糖類の分解を防ぐことができる。 As described above, in the potassium ion absorption inhibitor for foods according to the present invention, the potassium ion exchange polysaccharide is retained in the three-dimensional polymer, so that it is difficult to be hydrolyzed and absorbed itself. Can be prevented. In other words, because the potassium ion exchange ability polysaccharide is a natural product, unlike chemically synthesized ion exchange resins, it is easily decomposed by gastric acid, enzymes, enterobacteria, etc. in the digestive tract, reducing the potassium adsorption ability. End up. In order to prevent this, the present invention can prevent the decomposition of the potassium ion exchange polysaccharide by encapsulating the potassium ion exchange polysaccharide in the three-dimensional polymer.
三次元高分子が、カリウムイオン交換多糖類よりも消化器官内の抗分解能に優れている場合、三次元高分子が、胃酸や酵素、腸内細菌などによって分解され難く、一部分が分解されたとしても、三次元構造を保つことができるので、カリウムイオン交換多糖類の分解を防ぐことができる。また、三次元高分子が、カリウムイオン交換多糖類よりも消化器官内の抗分解能が同等か若しくは劣っている場合であっても、三次元高分子の三次元構造が崩壊された後でなければ、カリウムイオン交換多糖類が分解され難いので、カリウムイオン交換多糖類の分解を抑制することができる。 If the three-dimensional polymer is superior to potassium ion-exchange polysaccharide in anti-degradability in the digestive tract, the three-dimensional polymer is difficult to be decomposed by gastric acid, enzymes, intestinal bacteria, etc. In addition, since the three-dimensional structure can be maintained, the decomposition of the potassium ion exchange polysaccharide can be prevented. In addition, even if the three-dimensional polymer has a similar or inferior anti-resolution in the digestive tract than the potassium ion exchange polysaccharide, it must be after the three-dimensional structure of the three-dimensional polymer is destroyed. Since the potassium ion exchange polysaccharide is hardly decomposed, the decomposition of the potassium ion exchange polysaccharide can be suppressed.
一方、三次元高分子は、その中にカリウムイオンなど小さいものを透過させることができるが、カリウムイオン交換多糖類の分解に寄与する酵素など大きなものを透過させない、又は透過を遅らせることが好ましい。これにより、一度、三次元高分子内に透過されたカリウムイオンは、カリウムイオン交換多糖類に保持され、三次元高分子とともに排泄される。 On the other hand, the three-dimensional polymer can permeate small substances such as potassium ions, but it is preferable not to permeate large substances such as enzymes that contribute to the degradation of potassium ion-exchanged polysaccharides or to delay the permeation. Thereby, the potassium ion once permeated into the three-dimensional polymer is held in the potassium ion-exchange polysaccharide and excreted together with the three-dimensional polymer.
以上のように、本発明によれば、様々な食品形態にその食品の風味、香味などに影響を与えずに添加することが可能であるとともに、そのもの自体が部分吸収することが少ない食品用カリウム吸収抑制剤及びそれが含まれた食品を提供することができる。 As described above, according to the present invention, it is possible to add to various food forms without affecting the flavor, flavor, etc. of the food, and the food-use potassium that itself hardly partially absorbs. An absorption inhibitor and a food containing the same can be provided.
本発明に係る食品用カリウムイオン吸収抑制剤において、前記三次元高分子は、前記カリウムイオン交換多糖類よりも消化器官内における抗分解能が優れていることが好ましい。本発明において、消化器官内の抗分解能とは、消化器官内の胃酸や酵素、腸内細菌に対して分解され難い能力のことをいい、例えば日局第１液（人工胃液）や日局第２液（人工腸液）などに対して分解されにくく、分解されるのが遅いことをいう。具体的には、寒天やセルロースなどである。また、本発明に係る食品用カリウムイオン吸収抑制剤において、三次元高分子は、吸水膨潤した状態でも良く、あるいは均一なゲルの状態であっても良い。 In the food-use potassium ion absorption inhibitor according to the present invention, it is preferable that the three-dimensional polymer has better anti-resolution in the digestive tract than the potassium ion-exchange polysaccharide. In the present invention, the anti-decomposition in the digestive tract refers to the ability to be hardly decomposed by gastric acid, enzyme, and intestinal bacteria in the digestive tract. For example, JP 1st liquid (artificial gastric juice) or JP It means that it is difficult to be decomposed with respect to two liquids (artificial intestinal fluids) and is slowly decomposed. Specifically, it is agar or cellulose. In the food-use potassium ion absorption inhibitor according to the present invention, the three-dimensional polymer may be in a water-absorbed swollen state or in a uniform gel state.
本発明に係る食品用カリウムイオン吸収抑制剤において、前記カリウムイオン交換多糖類は、カラギナン、ファーセレラン、脱アシル型ジェランガム、ネイティブ型ジェランガム、アルギン酸及びその塩、ペクチン、カルボキシメチルセルロース及びその塩、アラビアガム、水素型アラビアガム、アラビノガラクタン、水素型アラビノガラクラン、サイリウムシードガム、並びにキサンタンガムのうちいずれか一以上であることが好ましい。カラギナンは、硫酸基をガラクトースの構成糖中に有する酸性多糖類であり、特に、カリウムイオン交換に有効なカラギナンとしては、ナトリウムカッパ型、ナトリウムイオタ型、ナトリウムラムダ型などであり、さらにナトリウムが除去された水素型も有効である。 In the food-use potassium ion absorption inhibitor according to the present invention, the potassium ion-exchange polysaccharide includes carrageenan, farseleran, deacylated gellan gum, native gellan gum, alginic acid and its salt, pectin, carboxymethylcellulose and its salt, gum arabic, One or more of hydrogen-type gum arabic, arabinogalactan, hydrogen-type arabinogalaclan, psyllium seed gum, and xanthan gum are preferable. Carrageenan is an acidic polysaccharide that has a sulfate group in the constituent sugar of galactose. In particular, carrageenans effective for potassium ion exchange include sodium kappa type, sodium iota type, sodium lambda type, and sodium is removed. The hydrogen form is also effective.
本発明に係る食品としては、例えばデザートゼリー、ところてん、みつ豆などのゼリー状食品などがある。 Examples of the food according to the present invention include dessert jelly, jelly-like foods such as Toroten and Mitsume.
次に、本発明に係る食品用カリウムイオン吸収抑制剤の実施例について説明する。先ず、三次元高分子として脱イオンされた寒天（伊那食品工業株式会社製：伊那寒天ＢＡ−１０）を用意し、この三次元高分子としての寒天を最終濃度０．８重量％、３００ｇの寒天水溶液となるように調整した。次に、表１に示すようにカリウムイオン交換多糖類として、脱アシル型ジェランガム（ＣＰケルコ社製）、ネイティブ型ジェランガム（ＣＰケルコ社製）、ナトリウムタイプカッパカラギナン（ＭＲＣポリサッカライド社製）、アルギン酸ナトリウム（キミカ製）、ペクチン（ＣＰケルコ社製）、カルボキシメチルセルロースナトリウム（第一工業製薬）、アラビアガム（ＣＮＪ社製）、水素型アラビアガム（伊那食品工業社製）、アラビノガラクタン（ＭＲＣポリサッカライド社製）、サイリウムシードガム（大日本製薬社製）、キサンタンガム（ＣＰケルコ社製）を用意し、これらカリウムイオン交換多糖類それぞれ５ｇをその寒天水溶液に添加し、加熱溶解させることによって、カリウムイオン交換多糖類を三次元高分子の三次元網目構造内に保持させ、実施例１乃至１１に係る食品用カリウムイオン吸収抑制剤を得た。また、比較例として医薬品に使用されているイオン交換樹脂であるポリスチレンスルホン酸ナトリウム５ｇを同様に寒天水溶液に溶解させた。これら実施例１乃至１１に係る食品用カリウムイオン吸収抑制剤、並びに比較例に係るカリウムイオン吸収抑制剤それぞれの液について均質な状態で冷却してゲル化させた。これらゲルをそれぞれ４ｍｍ×４ｍｍ×１０ｍｍの大きさに切断することによって検体を作製した。 Next, examples of the food-use potassium ion absorption inhibitor according to the present invention will be described. First, deionized agar (manufactured by Ina Food Industry Co., Ltd .: Ina Agar BA-10) is prepared as a three-dimensional polymer, and the agar as the three-dimensional polymer is agar with a final concentration of 0.8% by weight and 300 g. It adjusted so that it might become aqueous solution. Next, as shown in Table 1, as the potassium ion exchange polysaccharide, deacylated gellan gum (CP Kelco), native gellan gum (CP Kelco), sodium type kappa carrageenan (MRC polysaccharide), alginic acid Sodium (manufactured by Kimika), pectin (manufactured by CP Kelco), sodium carboxymethylcellulose (Daiichi Kogyo Seiyaku), gum arabic (manufactured by CNJ), hydrogen gum arabic (manufactured by Ina Food Industry), arabinogalactan (MRC Poly) Saccharide), psyllium seed gum (Dainippon Pharmaceutical Co., Ltd.), xanthan gum (CP Kelco), 5 g of each of these potassium ion exchange polysaccharides was added to the agar aqueous solution, and dissolved by heating. Three-dimensional network of ion-exchange polysaccharide and three-dimensional polymer It is retained within the concrete, to obtain a food potassium ion absorption inhibitor according to Examples 1 to 11. Further, as a comparative example, 5 g of sodium polystyrene sulfonate which is an ion exchange resin used in pharmaceuticals was similarly dissolved in an agar aqueous solution. The liquids of the potassium ion absorption inhibitor for food according to Examples 1 to 11 and the potassium ion absorption inhibitor according to the comparative example were cooled and gelled in a homogeneous state. Samples were prepared by cutting each of these gels into a size of 4 mm × 4 mm × 10 mm.
次に、これら実施例１乃至１１に係る食品用カリウムイオン吸収抑制剤、並びに比較例に係るカリウムイオン吸収抑制剤それぞれについて、日局パドル方を応用して、精製水、日局第１液（人工胃液）及び日局第２液（人工腸液）を使いカリウムの吸着試験（３７℃、１００ｒｐｍ、３０分）を行なった。カリウムイオンの定量は原子吸光法により測定した。比較例に係るカリウムイオン吸収抑制剤を１００％としたときの吸着率を計算した。その結果を表１に示す。 Next, for each of the potassium ion absorption inhibitor for food according to Examples 1 to 11 and the potassium ion absorption inhibitor according to the comparative example, purified water, JP 1st liquid ( Potassium adsorption test (37 ° C., 100 rpm, 30 minutes) was performed using artificial gastric fluid) and JP 2nd fluid (artificial intestinal fluid). Potassium ion was quantified by atomic absorption method. The adsorption rate when the potassium ion absorption inhibitor according to the comparative example was taken as 100% was calculated. The results are shown in Table 1.
表１に示すように、実施例１乃至１１に係る食品用カリウムイオン吸収抑制剤は、医薬品材料に用いられている比較例よりは効果は下がるものの有効な効果が認められ、腎臓疾患患者にとっては有効な食品と考えられる。
As shown in Table 1, the food-use potassium ion absorption inhibitor according to Examples 1 to 11 has an effective effect although it is less effective than the comparative example used in the pharmaceutical material. It is considered an effective food.
Claims (5)
A food comprising the food-use potassium ion absorption inhibitor according to any one of claims 1 to 4.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2005160885A JP4833585B2 (en) | 2005-06-01 | 2005-06-01 | Potassium absorption inhibitor for food and food containing the same |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2005160885A JP4833585B2 (en) | 2005-06-01 | 2005-06-01 | Potassium absorption inhibitor for food and food containing the same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006333751A true JP2006333751A (en) | 2006-12-14 |
| JP4833585B2 JP4833585B2 (en) | 2011-12-07 |
Family
ID=37554834
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2005160885A Expired - Fee Related JP4833585B2 (en) | 2005-06-01 | 2005-06-01 | Potassium absorption inhibitor for food and food containing the same |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP4833585B2 (en) |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61209573A (en) * | 1985-03-12 | 1986-09-17 | Nippon Terupen Kagaku Kk | Drink from which potassium is removed |
| JPH04190764A (en) * | 1990-11-27 | 1992-07-09 | R N Ee Kenkyusho Kk | Remedy for hyperkalemia, hyperlipidemia, deramatopathy or the like |
| JPH0975723A (en) * | 1995-07-20 | 1997-03-25 | Koki Bussan Kk | Harmful matter adsorbing and removing agent |
| JP2000270811A (en) * | 1999-03-25 | 2000-10-03 | Meiji Seika Kaisha Ltd | Food for suppressing absorption of potassium ion and method therefor |
-
2005
- 2005-06-01 JP JP2005160885A patent/JP4833585B2/en not_active Expired - Fee Related
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61209573A (en) * | 1985-03-12 | 1986-09-17 | Nippon Terupen Kagaku Kk | Drink from which potassium is removed |
| JPH04190764A (en) * | 1990-11-27 | 1992-07-09 | R N Ee Kenkyusho Kk | Remedy for hyperkalemia, hyperlipidemia, deramatopathy or the like |
| JPH0975723A (en) * | 1995-07-20 | 1997-03-25 | Koki Bussan Kk | Harmful matter adsorbing and removing agent |
| JP2000270811A (en) * | 1999-03-25 | 2000-10-03 | Meiji Seika Kaisha Ltd | Food for suppressing absorption of potassium ion and method therefor |
Also Published As
| Publication number | Publication date |
|---|---|
| JP4833585B2 (en) | 2011-12-07 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US6083935A (en) | Biocompatible aqueous solution for use in continuous ambulatory peritoneal dialysis | |
| TWI309569B (en) | Biocompatible dialysis fluids containing icodextrins | |
| JP2017537101A (en) | Dietary fiber composition | |
| WO2003053565A1 (en) | Adsorbent for phosphoric acid | |
| EP2004138B1 (en) | Gastric raft composition comprising processed starches for inducing satiety | |
| JP4833585B2 (en) | Potassium absorption inhibitor for food and food containing the same | |
| US20130197428A1 (en) | Peritoneal Dialysis Method | |
| US10695388B2 (en) | High molecular weight polymeric composition and a new usage of the high-molecular weight polymeric composition | |
| JP7084968B2 (en) | Fat and sugar absorption inhibitor, insulin resistance index lowering agent, adiponectin secretion promoting agent, hepatic triglyceride (TG) concentration lowering agent, bile acid adsorbent, manufacturing method of these agents, and beverages containing these agents. object | |
| CN107073032A (en) | Kidney failure progression inhibitors, prophylactic agent for renal failure and indoxyl sulfate produce inhibitor | |
| JP4001443B2 (en) | Phosphorus absorption inhibitor and therapeutic agent containing the same | |
| JP4616195B2 (en) | Composition containing a sparingly soluble salt of chitosan | |
| JP4741824B2 (en) | Acidic oligosaccharide | |
| JPH1094598A (en) | Peritoneal dialysis liquid | |
| CN110679797A (en) | Slimming beverage rich in konjac oligosaccharides and preparation method thereof | |
| JP2004051615A (en) | Bile acids adsorbent using chitosan-orotic acid salt | |
| RU2201755C2 (en) | Method for treating uremic syndrome | |
| JP6996460B2 (en) | Inhibitors, prophylaxis, and treatments for the progression of kidney disease | |
| JP2722131B2 (en) | Peritoneal dialysate | |
| JP7048167B2 (en) | Treatment of lifestyle-related diseases Water and treatment methods for lifestyle-related diseases | |
| JPH01500751A (en) | Treatment method | |
| EP1043022B1 (en) | Sodium ion absorption inhibitors and sodium ion excretion accelerators as preventive and therapeutic agents for diseases resulting from excessive intake of common salt | |
| Feriani et al. | New peritoneal dialysis solutions and solutions on the horizon | |
| JP2000093125A (en) | Drink or food comprising edible fibers | |
| CN113826787A (en) | Preparation method of functional soda water beverage for relieving gout |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20080529 |
|
| A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20090330 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20101221 |
|
| A521 | Written amendment |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20110204 |
|
| TRDD | Decision of grant or rejection written | ||
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20110906 |
|
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 |
|
| A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20110922 |
|
| R150 | Certificate of patent or registration of utility model |
Ref document number: 4833585 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
| FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20140930 Year of fee payment: 3 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| LAPS | Cancellation because of no payment of annual fees |