JP2006306812A5 - - Google Patents
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- Publication number
- JP2006306812A5 JP2006306812A5 JP2005133264A JP2005133264A JP2006306812A5 JP 2006306812 A5 JP2006306812 A5 JP 2006306812A5 JP 2005133264 A JP2005133264 A JP 2005133264A JP 2005133264 A JP2005133264 A JP 2005133264A JP 2006306812 A5 JP2006306812 A5 JP 2006306812A5
- Authority
- JP
- Japan
- Prior art keywords
- eosinophil infiltration
- inhibitor according
- eosinophil
- dgla
- infiltration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 210000003979 eosinophil Anatomy 0.000 claims 11
- 230000008595 infiltration Effects 0.000 claims 11
- 238000001764 infiltration Methods 0.000 claims 11
- 239000003112 inhibitor Substances 0.000 claims 6
- HOBAELRKJCKHQD-UHFFFAOYSA-N (8Z,11Z,14Z)-8,11,14-eicosatrienoic acid Natural products CCCCCC=CCC=CCC=CCCCCCCC(O)=O HOBAELRKJCKHQD-UHFFFAOYSA-N 0.000 claims 5
- HOBAELRKJCKHQD-QNEBEIHSSA-N dihomo-γ-linolenic acid Chemical compound CCCCC\C=C/C\C=C/C\C=C/CCCCCCC(O)=O HOBAELRKJCKHQD-QNEBEIHSSA-N 0.000 claims 5
- 102000004190 Enzymes Human genes 0.000 claims 2
- 108090000790 Enzymes Proteins 0.000 claims 2
- 201000010099 disease Diseases 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 125000005456 glyceride group Chemical group 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- LDVVTQMJQSCDMK-UHFFFAOYSA-N 1,3-dihydroxypropan-2-yl formate Chemical compound OCC(CO)OC=O LDVVTQMJQSCDMK-UHFFFAOYSA-N 0.000 claims 1
- HVCOBJNICQPDBP-UHFFFAOYSA-N 3-[3-[3,5-dihydroxy-6-methyl-4-(3,4,5-trihydroxy-6-methyloxan-2-yl)oxyoxan-2-yl]oxydecanoyloxy]decanoic acid;hydrate Chemical compound O.OC1C(OC(CC(=O)OC(CCCCCCC)CC(O)=O)CCCCCCC)OC(C)C(O)C1OC1C(O)C(O)C(O)C(C)O1 HVCOBJNICQPDBP-UHFFFAOYSA-N 0.000 claims 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical group [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims 1
- 208000006545 Chronic Obstructive Pulmonary Disease Diseases 0.000 claims 1
- 206010009900 Colitis ulcerative Diseases 0.000 claims 1
- 201000004624 Dermatitis Diseases 0.000 claims 1
- 206010012438 Dermatitis atopic Diseases 0.000 claims 1
- 235000021298 Dihomo-γ-linolenic acid Nutrition 0.000 claims 1
- 229930186217 Glycolipid Natural products 0.000 claims 1
- 201000004681 Psoriasis Diseases 0.000 claims 1
- 201000006704 Ulcerative Colitis Diseases 0.000 claims 1
- 239000004480 active ingredient Substances 0.000 claims 1
- 125000005907 alkyl ester group Chemical group 0.000 claims 1
- 208000006673 asthma Diseases 0.000 claims 1
- 201000008937 atopic dermatitis Diseases 0.000 claims 1
- 208000010668 atopic eczema Diseases 0.000 claims 1
- 210000004027 cell Anatomy 0.000 claims 1
- 230000002950 deficient Effects 0.000 claims 1
- 201000001564 eosinophilic gastroenteritis Diseases 0.000 claims 1
- 201000009580 eosinophilic pneumonia Diseases 0.000 claims 1
- 201000001155 extrinsic allergic alveolitis Diseases 0.000 claims 1
- 235000013305 food Nutrition 0.000 claims 1
- 235000021588 free fatty acids Nutrition 0.000 claims 1
- 210000003630 histaminocyte Anatomy 0.000 claims 1
- 208000022098 hypersensitivity pneumonitis Diseases 0.000 claims 1
- 208000030603 inherited susceptibility to asthma Diseases 0.000 claims 1
- 150000003904 phospholipids Chemical class 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 201000009732 pulmonary eosinophilia Diseases 0.000 claims 1
- 125000005457 triglyceride group Chemical group 0.000 claims 1
Priority Applications (10)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2005133264A JP2006306812A (ja) | 2005-04-28 | 2005-04-28 | 好酸球浸潤抑制剤 |
| EP19183855.6A EP3581178B1 (en) | 2005-02-14 | 2006-02-10 | Composition containing dihomo-(gamma)-linolenic acid (dgla) as active ingredient |
| CA2599112A CA2599112C (en) | 2005-02-14 | 2006-02-10 | Composition comprising dihomo-.gamma.-linolenic acid (dgla) as the active ingredient |
| PCT/JP2006/302787 WO2006085687A1 (ja) | 2005-02-14 | 2006-02-10 | ジホモ−γ−リノレン酸（ＤＧＬＡ）を有効成分として含んで成る組成物 |
| US11/884,199 US9006287B2 (en) | 2005-02-14 | 2006-02-10 | Composition comprising dihomo-γ-linolenic acid (DGLA) as active ingredient |
| EP06713928.7A EP1852114B1 (en) | 2005-02-14 | 2006-02-10 | Composition containing dihomo-y-linolenic acid (dgla) as active ingredient |
| CN2012100164426A CN102600174A (zh) | 2005-02-14 | 2006-02-14 | 含有有效成分二均-γ-亚麻酸(DGLA)的组成物 |
| CN 200610003112 CN101019853B (zh) | 2005-02-14 | 2006-02-14 | 含有有效成分二均-γ-亚麻酸(DGLA)的组成物 |
| US14/644,231 US9943495B2 (en) | 2005-02-14 | 2015-03-11 | Composition containing dihomo-γ-linolenic acid (DGLA) as the active ingredient |
| US15/911,806 US10342773B2 (en) | 2005-02-14 | 2018-03-05 | Composition containing dihomo-γ-linolenic acid (DGLA) as the active ingredient |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2005133264A JP2006306812A (ja) | 2005-04-28 | 2005-04-28 | 好酸球浸潤抑制剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006306812A JP2006306812A (ja) | 2006-11-09 |
| JP2006306812A5 true JP2006306812A5 (enExample) | 2008-03-27 |
Family
ID=37474109
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2005133264A Pending JP2006306812A (ja) | 2005-02-14 | 2005-04-28 | 好酸球浸潤抑制剤 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP2006306812A (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006306813A (ja) * | 2005-04-28 | 2006-11-09 | Suntory Ltd | 肥満細胞増殖抑制剤 |
| US9006287B2 (en) | 2005-02-14 | 2015-04-14 | Suntory Holdings Limited | Composition comprising dihomo-γ-linolenic acid (DGLA) as active ingredient |
| GB0907413D0 (en) | 2009-04-29 | 2009-06-10 | Equateq Ltd | Novel methods |
| US8293790B2 (en) | 2011-10-19 | 2012-10-23 | Dignity Sciences Limited | Pharmaceutical compositions comprising DGLA and benzoyl peroxide and methods of use thereof |
| EP3151825B1 (en) | 2014-06-04 | 2020-03-25 | DS Biopharma Limited | Pharmaceutical compositions comprising dgla and use of same |
| WO2021065659A1 (ja) | 2019-10-01 | 2021-04-08 | サントリーホールディングス株式会社 | アクアポリン３の発現調節を介した腸機能改善用組成物及びその使用 |
| US20210315851A1 (en) | 2020-04-03 | 2021-10-14 | Afimmune Limited | Compositions comprising 15-hepe and methods of treating or preventing hematologic disorders, and/or related diseases |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE47777B1 (en) * | 1978-01-23 | 1984-06-13 | Efamol Ltd | Pharmaceutical and dietary composition comprising gamma-linolenic acids |
| IE49783B1 (en) * | 1979-05-18 | 1985-12-11 | Efamol Ltd | Pharmaceutical and dietary composition comprising epsilon-linolenic acids |
| GB8302708D0 (en) * | 1983-02-01 | 1983-03-02 | Efamol Ltd | Pharmaceutical and dietary composition |
| GB8806737D0 (en) * | 1988-03-22 | 1988-04-20 | Efamol Holdings | Therapeutic composition & method |
| JPH04244023A (ja) * | 1991-01-29 | 1992-09-01 | Idemitsu Petrochem Co Ltd | ω６系不飽和脂肪酸含有薬剤 |
| JP2002047176A (ja) * | 2000-08-04 | 2002-02-12 | Idemitsu Technofine Co Ltd | ＩｇＥ産生抑制剤 |
| JP2006306813A (ja) * | 2005-04-28 | 2006-11-09 | Suntory Ltd | 肥満細胞増殖抑制剤 |
| JP5546087B2 (ja) * | 2005-02-14 | 2014-07-09 | サントリーホールディングス株式会社 | 皮膚疾患経口治療または予防剤 |
-
2005
- 2005-04-28 JP JP2005133264A patent/JP2006306812A/ja active Pending
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