JP2006254893A - Culture solution of coniferous polypore - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide [1] a medicine fulfilling anticancer and analgesic purposes for the so-called cancer pains of the terminal cancer without using a narcotic, to provide [2] a medicine expected of strong immunity-enhancing actions and antiviral actions and enhancement of a virus antibody value for intractable hepatitis C and to provide [3] a substance strongly enhancing immunity for rheumatic factors in systemic malignant rheumatism. <P>SOLUTION: The culture solution comprises a metabolite obtained during culture as follows. Hyphal spores of a mixture solution prepared by adding 1,500 cc of water, 400-600 g of a sugar, 100-200 g of peptone and 300-500 g of coniferous polypores are cultured at 20-30°C for 20-30 days. <P>COPYRIGHT: (C)2006,JPO&NCIPI

Description

Numerous drugs have been recognized and used as anticancer agents in culture fluids such as fungi and sarunoshikake and their metabolite polysaccharides. The effect is not necessarily sufficient for end-stage cancer, dry cancer, and cancer pain. Antiviral agents, immunity enhancing agents, and analgesic / anti-inflammatory agents are also used for severe refractory hepatitis and malignant rheumatic diseases, but they are temporarily relieved, but relapse worsening cannot be avoided. It is hard to say that the drug can be fully satisfied.

The goal was to develop anticancer agents, anti-rheumatic agents, antiviral agents, and immunity enhancing agents with strong immunity and immunity activation ability with few side effects.

Development and production process of anticancer agents, antiviral agents, anti-rheumatic agents, and powerful immunity enhancing agents as pharmaceuticals.

Add 1500cc of water, 400g to 600g of sugar, 100g to 200g of peptone as a mixed solution, add 300g to 500g of strain on the conifer and cultivate mycelium spores at 20 ° C to 30 ° C for 20 to 30 days. A culture solution containing the product is obtained.

The conifer Saru-koshi culture medium of the present invention is effective against end-stage cancer, so-called cancer pain, due to its powerful immunity enhancing action by internal use, and has strong immunity against rheumatoid factor against malignant systemic rheumatoid arthritis. We see that joint deformation is improved by the force-enhancing effect and that motor performance is improved.
Increased viral antibody levels and improvement in general condition are observed due to a strong immunity enhancing action against intractable hepatitis C.

BEST MODE FOR CARRYING OUT THE INVENTION

1500cc water, 400g-600g sugar, 100g-200g peptone, 300g-500g mixed with softwood squeeze, cultivated mycelium for 20-30 days at 20-30 ° C, containing metabolites A culture solution is obtained.

At 55 years old, undergoing uterine cancer surgery 10 years later at 65 years old, left upper limb left lower limb edema appeared and increased edema over 30 years; 35 years later at 90 years old, left upper limb left lower limb edema was approximately compared to right upper limb right lower limb More than four times, walking became impossible, and so-called cancer pain occurred due to malignant left pelvic granuloma and onset of left heel adenocarcinoma. Because of severe pain for 72 hours, the insomnia was completely ineffective and the analgesic / anti-inflammatory agent was completely ineffective, and the use of narcotics was also considered, but the conifer squeeze culture solution of the present invention was taken 20 cc 3 times a day after meals. After 24 hours, the pain was relieved, and after 72 hours, the pain disappeared. Seven days later, the edema of the left upper limb also significantly decreased and halved. This is thought to be due to the reduction of malignant granulation tissue and gonad cancer due to the strong immunity enhancing action of the conifer culture medium of the present invention.
The decrease in edema in the left upper limb and the left lower limb is thought to be due to the decrease in edema due to the reduction of malignant granulation tissue and left groin adenocarcinoma, releasing blood pressure in the left buttock and significantly improving blood flow. . This is an example in which the culture solution of the present invention as an anticancer agent had a remarkable effect.

Patients with refractory hepatitis C were considered to use interferon because of severe systemic weakness and immunodeficiency after onset. However, the conical culture solution of the present invention was taken twice a day after taking 20 cc, and after 6 months the general condition Marked improvement and marked increase in type C virus antibodies. This is a proof of an excellent immunity enhancing action.

In patients with malignant systemic rheumatoid arthritis, gait was completely difficult, but the deformities of both hands and dorsal joints were deformed. It became possible to walk. This is an example of remission by a strong immunity enhancing action.

Industrial applicability

Example

Due to its excellent potent immunity enhancing action, its potential as an anticancer agent, antiviral agent, and antirheumatic agent has been sufficiently confirmed.
It can be said that it is a epoch-making fact as a pharmaceutical that the end-stage cancer has been relieved at the onset of malignant rheumatism and hepatitis C by the strong immunity and activation effect of the coniferous culture medium of the present invention. In addition, I believe that this culture solution can also produce injection solutions, and will fully meet the expectations of the pharmaceutical manufacturing industry.

Claims (3)

Add 1500 cc water, 400 grams to 600 grams sugar, 100 grams to 200 grams peptone, 300 grams to 500 grams of softwood squeeze, and cultivate mycelium spores as a mixture at 20-30 ° C for 20-30 days, Medium containing the metabolite of We have succeeded in the pure culture of mycelium spores in the middle of conifers. In other words, it is a mycelial spores of a softwood monkey. Claims (1) (2) and all substances such as metabolite polysaccharides produced during the process.
Needless to say, the applications of the substances (1), (2) and (3) are included in the scope of the present invention.