JP2006094827A5 - - Google Patents
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- JP2006094827A5 JP2006094827A5 JP2004287226A JP2004287226A JP2006094827A5 JP 2006094827 A5 JP2006094827 A5 JP 2006094827A5 JP 2004287226 A JP2004287226 A JP 2004287226A JP 2004287226 A JP2004287226 A JP 2004287226A JP 2006094827 A5 JP2006094827 A5 JP 2006094827A5
- Authority
- JP
- Japan
- Prior art keywords
- megakaryocyte
- factor
- differentiation
- tpo cells
- platelets
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Claims (4)
（１）候補因子をＵＴ−７／ＴＰＯ細胞に添加する工程、および
（２）ＵＴ−７／ＴＰＯ細胞が血小板に分化したか否かを判定する工程
を含む方法。 A method for identifying factors that induce and / or promote differentiation of megakaryocytes to platelets, comprising:
(1) adding a candidate factor to UT-7 / TPO cells, and (2) determining whether the UT-7 / TPO cells have differentiated into platelets.
（１）候補因子をＵＴ−７／ＴＰＯ細胞に添加する工程、および
（２）ＵＴ−７／ＴＰＯ細胞が巨核球胞体突起（ｐｒｏｐｌａｔｅｌｅｔ）に分化したか否かを判定する工程
を含む方法。 A method for identifying a factor that induces and / or promotes differentiation of a megakaryocyte to a megakaryocyte proplet, comprising:
(1) adding a candidate factor to UT-7 / TPO cells, and (2) determining whether the UT-7 / TPO cells have differentiated into megakaryocyte projections.
（１）フィブロネクチンおよび候補因子をＵＴ−７／ＴＰＯ細胞の培養液中に添加する工程、
（２）ＵＴ−７／ＴＰＯ細胞から血小板への分化が阻害および／または抑制されたか否かを判定する工程
を包含する方法。 A method for identifying a factor that inhibits and / or suppresses differentiation of megakaryocytes into platelets, comprising:
(1) A step of adding fibronectin and a candidate factor into a culture solution of UT-7 / TPO cells,
(2) A method comprising a step of determining whether differentiation from UT-7 / TPO cells into platelets is inhibited and / or suppressed.
（１）フィブロネクチンおよび候補因子をＵＴ−７／ＴＰＯ細胞の培養液中に添加する工程、
（２）ＵＴ−７／ＴＰＯ細胞から巨核球胞体突起（ｐｒｏｐｌａｔｅｌｅｔ）への分化が阻害および／または抑制されたか否かを判定する工程
を包含する方法。 A method for identifying a factor that inhibits and / or suppresses differentiation of a megakaryocyte into a megakaryocyte propellate, comprising:
(1) A step of adding fibronectin and a candidate factor into a culture solution of UT-7 / TPO cells,
(2) A method comprising the step of determining whether differentiation from UT-7 / TPO cells to megakaryocyte prosthetics is inhibited and / or suppressed.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2004287226A JP2006094827A (en) | 2004-09-30 | 2004-09-30 | Method for identifying factor for adjusting platelet differentiation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2004287226A JP2006094827A (en) | 2004-09-30 | 2004-09-30 | Method for identifying factor for adjusting platelet differentiation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006094827A JP2006094827A (en) | 2006-04-13 |
| JP2006094827A5 true JP2006094827A5 (en) | 2007-10-11 |
Family
ID=36235225
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004287226A Pending JP2006094827A (en) | 2004-09-30 | 2004-09-30 | Method for identifying factor for adjusting platelet differentiation |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP2006094827A (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2570483B1 (en) * | 2010-05-14 | 2015-07-08 | Bloom Technology Co., Ltd. | Screening method for substance having hemocyte maturation acceleration action |
-
2004
- 2004-09-30 JP JP2004287226A patent/JP2006094827A/en active Pending
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