JP2006083120A - Germicidal disinfectant composition - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a gel-like germicidal disinfectant composition free of sags from hand or the like in use, getting nongreasy both in use and after use, free of feeling of being left after use, and affording dry feeling in use. <P>SOLUTION: The germicidal disinfectant composition comprises (A) a carboxyvinyl polymer, (B) an acrylic acid-methacrylic acid alkyl ester copolymer, (C) a germicidal disinfectant and (D) a lower alcohol. Furthermore, this composition can also contain (E) a cyclic silicone. <P>COPYRIGHT: (C)2006,JPO&NCIPI

Description

  The present invention relates to a sterilizing and disinfecting agent, and more particularly, to a sterilizing and disinfecting composition that can be easily sterilized and disinfected simply by being worn on a hand or a finger.

  Conventionally, washing with soap or the like is generally performed for sterilization of hands and fingers. However, there is a problem that hands and fingers cannot be washed in places where water cannot be used, such as outdoors. In addition, in order to prevent nosocomial infections in hospitals, it is necessary to wash hands and fingers of hospital workers and visitors. However, washing with soap etc. is cumbersome and is difficult to implement thoroughly. There is.

  In order to solve such a problem, a gel-like disinfectant that can be sterilized by thickening using a carboxyvinyl polymer or a cellulosic polymer and simply rubbing it on a hand or finger has been proposed ( For example, see Patent Documents 1 to 3).

  However, when a carboxyvinyl polymer is used as a thickener, there are disadvantages such as a decrease in viscosity due to the salt content of hands and fingers, and precipitation of the carboxyvinyl polymer, causing dripping from the hand during use and twisting. Moreover, when a cellulosic polymer is used as a thickening agent, there are disadvantages that the thickening effect is inferior, and that a null feeling during use and a residual feeling after use occur.

JP-A-6-199700 Japanese Patent Laid-Open No. 11-9667 JP 2000-86408 A

  The present invention has been made in view of the above prior art, and does not sag from the hand or twist when used, is not sticky both at the time of use and after use, has no residual feeling of the preparation after use, and gently It is an object of the present invention to provide a gel-like disinfectant composition that provides a feeling of use.

That is, the invention according to claim 1 is characterized by containing (A) a carboxyvinyl polymer, (B) an acrylic acid / alkyl methacrylate copolymer, (C) a disinfectant and a (D) lower alcohol. The present invention relates to a disinfectant composition.
The invention according to claim 2 is characterized in that the content ratio of the component (A) and the component (B) is (A) :( B) = 0.5: 1 to 5: 1 by weight. The disinfectant composition according to claim 1.
The invention according to claim 3 is that (C) the disinfectant is benzalkonium chloride, benzethonium chloride, triclosan, isopropylmethylphenol, cetylpyridinium chloride, resorcin, trichlorocarbanide, halocarban, chlorhexidine hydrochloride, chlorhexidine gluconate, The disinfectant composition according to claim 1 or 2, wherein the composition is one or more selected from the group consisting of acrinol, hydrogen peroxide, popidone iodine and iodine tincture.
The invention according to claim 4 relates to the disinfectant composition according to any one of claims 1 to 3, wherein the content of (D) the lower alcohol is 40 to 90% by weight.
The invention according to claim 5 relates to the disinfectant composition according to any one of claims 1 to 4, characterized in that (E) a cyclic silicone is contained.
The invention according to claim 6 is characterized in that the (E) cyclic silicone is at least one selected from the group consisting of octamethylcyclotetrasiloxane, decamethylcyclopentasiloxane, dodecamethylcyclohexasiloxane, and methylcyclopolysiloxane. The disinfectant composition according to claim 5.
The invention according to claim 7 relates to the disinfectant composition according to any one of claims 1 to 6, which is substantially free of a surfactant.
The invention according to claim 8 relates to the disinfectant composition according to any one of claims 1 to 7, which is non-detergency.

  The bactericidal disinfectant composition of the present invention is free from sagging from hands, sticky, or twisted during use, and has an effect that there is no residual feeling of the preparation after use, and a light feeling of use can be obtained. Moreover, since it is excellent in the feeling of use after use, there is an effect that sterilization and sterilization can be performed by simply rubbing on the fingers without washing the fingers with water.

  The disinfectant composition according to the present invention contains (A) a carboxyvinyl polymer, (B) an acrylic acid / alkyl methacrylate copolymer, (C) a disinfectant and (D) a lower alcohol.

  In the present invention, (A) carboxyvinyl polymer is contained as a thickener. Examples of commercially available carboxyvinyl polymers preferably used in the present invention include Carbopol 940 and Carbopol 941 (all manufactured by BF Goodrich), Hibiswaco K-100, Hibiswaco K-200 (Wako Pure Chemical Industries, Ltd.). Etc.).

  The content of the carboxyvinyl polymer is not particularly limited as long as the effect of the present invention is exhibited, but is preferably 0.01 to 2% by weight, more preferably 0.05 to 1% by weight in the composition. . If the amount is less than 0.01% by weight, the thickening effect is inferior and dripping occurs during use. If the amount exceeds 2% by weight, the feeling during use and after use deteriorates. Is also not preferable.

  In the present invention, (B) an acrylic acid / alkyl methacrylate copolymer is further contained as a thickener. The acrylic acid / alkyl methacrylate copolymer to be contained is not particularly limited, but is preferably one in which the alkyl group of the methacrylic acid unit has 10 to 30 carbon atoms. Commercially available acrylic acid / alkyl methacrylate copolymers suitably used in the present invention include trade names Pemulen TR-1, Pemulen TR-2, Carbopol 1342, Carbopol 1382, ETD2020 (all manufactured by BF Goodrich) Etc. can be illustrated.

  The content of the acrylic acid / alkyl methacrylate copolymer is not particularly limited as long as the effect of the present invention is exhibited, but is preferably 0.01 to 2% by weight in the composition, and 0.05 to 1% by weight. Is more preferable. If the amount is less than 0.01% by weight, the thickening effect is inferior and dripping occurs during use. If the amount exceeds 2% by weight, the feeling during use and after use deteriorates. Is also not preferable.

  In addition, it is preferable to contain the two components (A) and (B) at a specific weight ratio in order to improve the feeling of use such as stickiness and to prevent twisting. The content ratio of (A) carboxyvinyl polymer and (B) acrylic acid / alkyl methacrylate copolymer is preferably a weight ratio of (A) :( B) = 0.5: 1 to 5: 1. , 1: 1 to 3: 1 is more preferable. When the content of the component (A) is less than 0.5 parts by weight relative to 1 part by weight of the component (B), the usability after use or after use is inferior, and (A) If the content of the component exceeds 5 parts by weight, liquid dripping or twisting may occur during use, which is not preferable in any case.

  In the present invention, a basic substance is added to neutralize (A) the carboxyvinyl polymer and (B) the acrylic acid / alkyl methacrylate copolymer to form a gel. Examples of the basic substance used include organic amines such as triethanolamine, monoethanolamine, and 2-amino-2-methyl-1-propanol, and inorganic bases such as ammonia, potassium hydroxide, and sodium hydroxide. Is exemplified. The blending amount of the basic substance is an amount capable of thickening the carboxyvinyl polymer or the acrylic acid / alkyl methacrylate copolymer, and an amount sufficient for neutralization may be appropriately blended according to the base used.

  (C) The disinfectant is not particularly limited as long as it can sterilize and disinfect microorganisms attached to the finger. For example, benzalkonium chloride, benzethonium chloride, triclosan, isopropylmethylphenol, cetylpyridinium chloride, resorcin, Examples include trichlorocarbanide, halocarban, chlorhexidine hydrochloride, chlorhexidine gluconate, acrinol, hydrogen peroxide, popidone iodine, iodotin tincture and the like. Of these, benzalkonium chloride, trichlorocarbanide, chlorhexidine gluconate, triclosan, and isopropylmethylphenol are preferably used from the viewpoint of the effectiveness of sterilization and sterilization, and benzalkonium chloride and trichlorocarbanide are used. Is more preferable.

  The content of the bactericidal disinfectant is not particularly limited as long as the effect of the present invention is exerted, but is preferably 0.01 to 5% by weight, more preferably 0.05 to 2% by weight in the composition. . If it is less than 0.01% by weight, the effect of sterilization and sterilization cannot be expected. If it exceeds 5% by weight, it is not preferable in any case from the viewpoint of safety such as irritation.

  (D) Lower alcohol is C1-C5 alcohol, can illustrate methanol, ethanol, n-propanol, isopropanol, n-butanol etc., It is preferable to use ethanol and isopropanol.

  Although content of a lower alcohol will not be specifically limited if the effect of this invention is exhibited, It is preferable to set it as 40 to 90 weight% in a composition, and 60 to 80 weight% is more preferable. If it is less than 40% by weight, the drying rate after use is slow, and if it exceeds 90% by weight, skin irritation occurs, which is not preferable in any case.

  In the present invention, in order to further improve the feeling during use or after use, (E) a cyclic silicone can be further contained. The cyclic silicone used is not particularly limited as long as the effects of the present invention can be exhibited, and it is preferable to use a low-boiling cyclic silicone oil having volatility. Such a cyclic silicone is represented by the general formula of the following formula (1), and specific examples include octamethylcyclotetrasiloxane, decamethylcyclopentasiloxane, dodecamethylcyclohexasiloxane, methylcyclopolysiloxane and the like. It is preferable to use decamethylcyclopentasiloxane or methylcyclopolysiloxane.

  Although content of cyclic silicone is not specifically limited, It is preferable to set it as 0.01 to 2 weight% in a composition, and it is more preferable to set it as 0.05 to 1 weight%. If it is less than 0.01% by weight, the feeling after use is not excellent, and if it exceeds 2% by weight, the hand becomes slippery.

  Water can be mix | blended with the disinfectant composition of this invention in order to adjust the drying rate after use. The blending amount is preferably 9 to 49% by weight, more preferably 19 to 35% by weight in the composition.

  Moreover, it is preferable that the disinfectant composition of the present invention does not substantially contain a surfactant. When a surfactant is contained, a residual feeling of the preparation is generated after use, which is not preferable. Therefore, it is preferable that the disinfectant composition of the present invention is non-detergent that does not contain a surfactant.

  EXAMPLES Hereinafter, although this invention is further demonstrated based on an Example, this invention is not limited only to this Example. Unless otherwise specified, the blending amount is expressed in weight%.

(Sample preparation)
According to the composition described in Table 1, each sample of Examples and Comparative Examples was prepared by a conventional method and subjected to the following evaluation.

(Test Example 1: Evaluation of dripping)
A fixed amount of each sample was taken and the dripping from the hand when it was applied to the fingers was evaluated. Evaluation was conducted by 10 expert panelists according to the following evaluation criteria, and the average was adopted. The results are shown in Table 1.
<Evaluation criteria>
○: No dripping Δ: Some dripping ×: Dripping

(Test Example 2: Evaluation of stickiness)
A certain amount of each sample was picked up, and the stickiness of the fingers after use (when used) and after use was evaluated. Evaluation was conducted by 10 expert panelists according to the following evaluation criteria, and the average was adopted. The results are shown in Table 1.
<Evaluation criteria>
○: Not sticky both after use and after use △: Sticky slightly after use or after use ×: Sticky after use or after use

(Test Example 3: Evaluation of twist)
A certain amount of each sample was taken and evaluated for twisting of the polymer component when it was applied to the fingers. Evaluation was conducted by 10 expert panelists according to the following evaluation criteria, and the average was adopted. The results are shown in Table 1.
<Evaluation criteria>
○: No twisting △: Some twisting occurs ×: Twisting occurs

(Test Example 4: Evaluation of residual feeling)
A certain amount of each sample was picked up, and the residual feeling of each sample on the fingers after being applied to the fingers was evaluated. Evaluation was conducted by 10 expert panelists according to the following evaluation criteria, and the average was adopted. The results are shown in Table 1.
<Evaluation criteria>
○: No residual feeling Δ: Some residual feeling ×: Residual feeling

  From the results shown in Table 1, the disinfectant composition according to the present invention has no dripping from the hand, no twist, no stickiness both at the time of use and after use, and there is no residual feeling of the preparation after use. It can be seen that a smooth use feeling is obtained. Further, it can be seen that when a cyclic silicone is further contained, the feeling of use at the time of use and after use can be further improved, and the twist of the preparation in use can be further prevented.

  The bactericidal disinfectant composition of the present invention has no dripping or twisting from the hands during use, and is not sticky both at the time of use and after use. Since it is obtained, it can be sterilized and sterilized by simply rubbing it on the fingers without washing the fingers with water, and thus can be suitably used as a sterilizing and disinfecting agent.

Claims (8)

A disinfectant composition comprising (A) a carboxyvinyl polymer, (B) an acrylic acid / alkyl methacrylate copolymer, (C) a disinfectant and (D) a lower alcohol. 2. The content ratio of the component (A) and the component (B) is (A) :( B) = 0.5: 1 to 5: 1 as a weight ratio. Disinfectant composition. (C) bactericidal disinfectant is benzalkonium chloride, benzethonium chloride, triclosan, isopropylmethylphenol, cetylpyridinium chloride, resorcin, trichlorocarbanide, halocarban, chlorhexidine hydrochloride, chlorhexidine gluconate, acrinol, hydrogen peroxide, popidone iodine and The disinfectant composition according to claim 1 or 2, wherein the disinfectant composition is one or more selected from the group of iodine tinctures. (D) Content of a lower alcohol is 40 to 90 weight%, The disinfection disinfectant composition in any one of Claims 1-3 characterized by the above-mentioned. (E) Cyclic silicone is contained, The disinfectant composition as described in any one of Claims 1-4 characterized by the above-mentioned. The cyclic silicone (E) is at least one selected from the group consisting of octamethylcyclotetrasiloxane, decamethylcyclopentasiloxane, dodecamethylcyclohexasiloxane, and methylcyclopolysiloxane. Disinfectant composition. The disinfectant composition according to any one of claims 1 to 6, which substantially does not contain a surfactant. The disinfectant composition according to any one of claims 1 to 7, wherein the disinfectant composition is non-cleanable.