JP2005537032A5 - - Google Patents

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Publication number
JP2005537032A5
JP2005537032A5 JP2004569756A JP2004569756A JP2005537032A5 JP 2005537032 A5 JP2005537032 A5 JP 2005537032A5 JP 2004569756 A JP2004569756 A JP 2004569756A JP 2004569756 A JP2004569756 A JP 2004569756A JP 2005537032 A5 JP2005537032 A5 JP 2005537032A5
Authority
JP
Japan
Prior art keywords
adzyme
substrate
catalytic domain
targeting moiety
polypeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2004569756A
Other languages
English (en)
Japanese (ja)
Other versions
JP2005537032A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2003/026937 external-priority patent/WO2004019878A2/en
Publication of JP2005537032A publication Critical patent/JP2005537032A/ja
Publication of JP2005537032A5 publication Critical patent/JP2005537032A5/ja
Pending legal-status Critical Current

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JP2004569756A 2002-08-27 2003-08-27 アドザイムおよびその用途 Pending JP2005537032A (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US40651702P 2002-08-27 2002-08-27
US42375402P 2002-11-05 2002-11-05
US43000102P 2002-11-27 2002-11-27
PCT/US2003/026937 WO2004019878A2 (en) 2002-08-27 2003-08-27 Adzymes and uses thereof

Publications (2)

Publication Number Publication Date
JP2005537032A JP2005537032A (ja) 2005-12-08
JP2005537032A5 true JP2005537032A5 (enExample) 2006-10-19

Family

ID=31982336

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2004569756A Pending JP2005537032A (ja) 2002-08-27 2003-08-27 アドザイムおよびその用途

Country Status (6)

Country Link
US (2) US20040081647A1 (enExample)
EP (1) EP1539941A4 (enExample)
JP (1) JP2005537032A (enExample)
AU (1) AU2003262937B2 (enExample)
CA (1) CA2497047A1 (enExample)
WO (1) WO2004019878A2 (enExample)

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US20060024289A1 (en) * 2002-10-02 2006-02-02 Ruggles Sandra W Cleavage of VEGF and VEGF receptor by wild-type and mutant proteases
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US7939304B2 (en) * 2002-10-02 2011-05-10 Catalyst Biosciences, Inc. Mutant MT-SP1 proteases with altered substrate specificity or activity
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US20080221029A1 (en) * 2002-10-31 2008-09-11 Regents Of The University Of Colorado Methods for treatment of thiol-containing compound deficient conditions
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WO2005087947A2 (en) * 2004-03-09 2005-09-22 Meyer Pharmaceuticals Llc Bioengineered proteolytic enzymes with enhanced specificity for cytokine receptors
AU2005244271B2 (en) 2004-04-12 2010-04-08 Vertex Pharmaceuticals Incorporated Cleavage of VEGF and VEGF receptor by wildtype and mutant MT-SP1
US20090042780A1 (en) * 2004-05-20 2009-02-12 Acceleron Pharma Inc Modified TGF-Beta Superfamily Polypeptides and Related Methods
US7468350B2 (en) 2004-06-16 2008-12-23 Pneumrx, Inc. Glue composition for lung volume reduction
US20050281740A1 (en) * 2004-06-16 2005-12-22 Glen Gong Imaging damaged lung tissue
US7608579B2 (en) * 2004-06-16 2009-10-27 Pneumrx, Inc. Lung volume reduction using glue compositions
US7553810B2 (en) * 2004-06-16 2009-06-30 Pneumrx, Inc. Lung volume reduction using glue composition
US20050281798A1 (en) * 2004-06-16 2005-12-22 Glen Gong Targeting sites of damaged lung tissue using composition
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US7678767B2 (en) 2004-06-16 2010-03-16 Pneumrx, Inc. Glue compositions for lung volume reduction
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WO2008048685A2 (en) * 2006-10-19 2008-04-24 Duke University Ox40 aptamers
MY157916A (en) 2006-07-21 2016-08-15 Xyleco Inc Conversion system for biomass
CA2670471A1 (en) 2006-11-22 2008-06-05 Adnexus, A Bristol-Myers Squibb R&D Company (A Delaware Corporation) Targeted therapeutics based on engineered proteins for tyrosine kinases receptors, including igf-ir
AU2007343610C1 (en) * 2007-01-17 2013-11-07 Immunomedics, Inc. Polymeric carriers of therapeutic agents and recognition moieties for antibody-based targeting of disease sites
US7680553B2 (en) * 2007-03-08 2010-03-16 Smp Logic Systems Llc Methods of interfacing nanomaterials for the monitoring and execution of pharmaceutical manufacturing processes
WO2009002607A1 (en) * 2007-05-01 2008-12-31 Dana-Farber Cancer Institute, Inc. Compositions and methods for identifying transforming and tumor suppressor genes
CN102007145A (zh) 2008-02-14 2011-04-06 百时美施贵宝公司 基于结合egfr的工程化蛋白质的靶向治疗剂
EP2799448A1 (en) 2008-05-22 2014-11-05 Bristol-Myers Squibb Company Multivalent fibronectin based scaffold domain proteins
US20100099609A1 (en) * 2008-07-28 2010-04-22 Buck Institute For Age Research eAPP AND DERIVATIVES FOR TREATMENT OF ALZHEIMER'S DISEASE
CN110187119B (zh) * 2008-10-31 2022-07-29 耶鲁大学 子痫前期检测和治疗的方法和组合物
SG172985A1 (en) * 2009-01-15 2011-08-29 Glutagen Pty Ltd Compositions for the treatment of gluten intolerance and uses thereof
WO2011050263A2 (en) * 2009-10-23 2011-04-28 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Systemic immunosuppression in the treatment of age related macular degeneration and diabetic retinopathy
ITBG20120050A1 (it) * 2012-10-29 2013-01-28 Michele Mutti Proteina di fusione con attività proteasica e specificità degli anticorpi
EP3445400A1 (en) * 2016-04-22 2019-02-27 Medimmune Limited Conjugated protease targeting moieties
US11603394B2 (en) 2016-10-04 2023-03-14 University Of Florida Research Foundation, Incorporated Targeted effector proteins and uses thereof
US11407797B2 (en) 2017-10-11 2022-08-09 University Of Florida Research Foundation, Incorporated Modified gal-1 proteins and uses thereof
MX2020012252A (es) * 2018-05-14 2021-04-28 Werewolf Therapeutics Inc Polipeptidos de interleucina 12 activables y metodos de uso de los mismos.
WO2025114429A1 (en) * 2023-11-29 2025-06-05 Intract Pharma Ltd Transcytosing composition

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