JP2005529067A5 - - Google Patents
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- Publication number
- JP2005529067A5 JP2005529067A5 JP2003561603A JP2003561603A JP2005529067A5 JP 2005529067 A5 JP2005529067 A5 JP 2005529067A5 JP 2003561603 A JP2003561603 A JP 2003561603A JP 2003561603 A JP2003561603 A JP 2003561603A JP 2005529067 A5 JP2005529067 A5 JP 2005529067A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- composition according
- subject
- treated
- ccr5
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 13
- 239000003067 chemokine receptor CCR5 antagonist Substances 0.000 claims 5
- 102000004127 Cytokines Human genes 0.000 claims 4
- 108090000695 Cytokines Proteins 0.000 claims 4
- 206010020843 Hyperthermia Diseases 0.000 claims 3
- 230000036031 hyperthermia Effects 0.000 claims 3
- 230000000770 proinflammatory effect Effects 0.000 claims 3
- 230000003938 response to stress Effects 0.000 claims 3
- 238000001356 surgical procedure Methods 0.000 claims 3
- 102100035875 C-C chemokine receptor type 5 Human genes 0.000 claims 2
- 101710149870 C-C chemokine receptor type 5 Proteins 0.000 claims 2
- 241000124008 Mammalia Species 0.000 claims 1
- 230000005764 inhibitory process Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US35086802P | 2002-01-22 | 2002-01-22 | |
| US36509702P | 2002-03-18 | 2002-03-18 | |
| PCT/US2003/001874 WO2003061659A1 (en) | 2002-01-22 | 2003-01-22 | Treating stress response with chemokine receptor ccr5 modulators |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005529067A JP2005529067A (ja) | 2005-09-29 |
| JP2005529067A5 true JP2005529067A5 (enExample) | 2006-03-09 |
Family
ID=27616781
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003561603A Pending JP2005529067A (ja) | 2002-01-22 | 2003-01-22 | ケモカイン受容体ｃｃｒ５モジュレータによるストレス応答の治療 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20050079176A1 (enExample) |
| EP (1) | EP1469849A4 (enExample) |
| JP (1) | JP2005529067A (enExample) |
| AU (1) | AU2003207646C1 (enExample) |
| CA (1) | CA2472682A1 (enExample) |
| WO (1) | WO2003061659A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2507704A1 (en) * | 2002-12-02 | 2004-06-17 | Mars, Incorporated | Flavanols and procyanidins promote homeostasis |
| ES2431524T3 (es) | 2004-04-13 | 2013-11-26 | Incyte Corporation | Derivados de piperazinilpiperidina como antagonistas de los receptores de quimiocinas |
| EP2493889B1 (en) | 2009-10-30 | 2017-09-06 | Janssen Pharmaceutica, N.V. | IMIDAZO[1,2-b]PYRIDAZINE DERIVATIVES AND THEIR USE AS PDE10 INHIBITORS |
| AR080754A1 (es) | 2010-03-09 | 2012-05-09 | Janssen Pharmaceutica Nv | Derivados de imidazo (1,2-a) pirazina y su uso como inhibidores de pde10 |
| MX344600B (es) | 2011-06-27 | 2016-12-20 | Janssen Pharmaceutica Nv | Derivados de 1-aril-4-metil-[1,2,4]triazolo[4,3-a]quinoxalina. |
| WO2013071061A1 (en) * | 2011-11-11 | 2013-05-16 | The Children's Hospital Of Philadelphia | Compositions and methods for increasing stress resilience |
| HK1206250A1 (en) | 2012-06-26 | 2016-01-08 | Janssen Pharmaceutica Nv | Combinations comprising pde 2 inhibitors such as 1-aryl-4-methyl-[1,2,4] triazolo [4,3-a] quinoxaline compounds and ped 10 inhibitors for use in the treatment of neurological or metabolic disorders |
| CN104411314B (zh) | 2012-07-09 | 2017-10-20 | 詹森药业有限公司 | 磷酸二酯酶10的抑制剂 |
| EP3143005B1 (en) * | 2014-05-16 | 2021-07-07 | Emory University | Chemokine cxcr4 and ccr5 receptor modulators and used related thereto |
| US11045546B1 (en) | 2020-03-30 | 2021-06-29 | Cytodyn Inc. | Methods of treating coronavirus infection |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0927167A1 (en) * | 1996-08-14 | 1999-07-07 | Warner-Lambert Company | 2-phenyl benzimidazole derivatives as mcp-1 antagonists |
| US5919776A (en) * | 1996-12-20 | 1999-07-06 | Merck & Co., Inc. | Substituted aminoquinolines as modulators of chemokine receptor activity |
| AR011057A1 (es) * | 1997-01-08 | 2000-08-02 | Smithkline Beecham Corp | Uso de bis-acridinas sustituidas y compuestos afines para la preparacion de medicamentos y dichos compuestos |
| AU9019098A (en) * | 1997-08-15 | 1999-03-08 | Advanced Research And Technology Institute, Inc. | Functional characterization of the c-c chemokine-like molecules encoded by molluscum contagiosum virus types 1 and |
| JP2000020198A (ja) * | 1998-07-06 | 2000-01-21 | Fujitsu Ltd | 端末制御方法及びそれを用いた端末装置並びにそれを実現するプログラムを記録したコンピュータ読み取り可能な記録媒体 |
| JP2002535256A (ja) * | 1999-01-25 | 2002-10-22 | スミスクライン・ビーチャム・コーポレイション | 化合物および方法 |
| US6358979B1 (en) * | 1999-06-11 | 2002-03-19 | Merck & Co., Inc. | N-cyclopentyl modulators of chemokine receptor activity |
| AU772321B2 (en) * | 1999-06-11 | 2004-04-22 | Merck Sharp & Dohme Corp. | N-cyclopentyl modulators of chemokine receptor activity |
| WO2001051077A1 (en) * | 2000-01-14 | 2001-07-19 | The Government Of The United States Of Americarep Resented By The Secretary, Department Of Health And Human Services | Methods of regulating il-12 production by administering ccr5 agonists and antagonists |
| AU2001253495A1 (en) * | 2000-04-14 | 2001-10-30 | Millennium Pharmaceuticals, Inc. | Treating graft rejection with ccr5 inhibitors |
-
2003
- 2003-01-22 EP EP03705865A patent/EP1469849A4/en not_active Withdrawn
- 2003-01-22 US US10/501,999 patent/US20050079176A1/en not_active Abandoned
- 2003-01-22 CA CA002472682A patent/CA2472682A1/en not_active Abandoned
- 2003-01-22 AU AU2003207646A patent/AU2003207646C1/en not_active Ceased
- 2003-01-22 JP JP2003561603A patent/JP2005529067A/ja active Pending
- 2003-01-22 WO PCT/US2003/001874 patent/WO2003061659A1/en not_active Ceased
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