JP2005528383A5 - - Google Patents

Download PDF

Info

Publication number
JP2005528383A5
JP2005528383A5 JP2003583294A JP2003583294A JP2005528383A5 JP 2005528383 A5 JP2005528383 A5 JP 2005528383A5 JP 2003583294 A JP2003583294 A JP 2003583294A JP 2003583294 A JP2003583294 A JP 2003583294A JP 2005528383 A5 JP2005528383 A5 JP 2005528383A5
Authority
JP
Japan
Prior art keywords
capsule
component
containment chamber
physical state
base portion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2003583294A
Other languages
Japanese (ja)
Other versions
JP2005528383A (en
Filing date
Publication date
Priority claimed from US10/369,247 external-priority patent/US20030194430A1/en
Application filed filed Critical
Priority claimed from PCT/US2003/010816 external-priority patent/WO2003086267A2/en
Publication of JP2005528383A publication Critical patent/JP2005528383A/en
Publication of JP2005528383A5 publication Critical patent/JP2005528383A5/ja
Pending legal-status Critical Current

Links

Claims (10)

複数コンパートメントカプセルを形成するためのカプセル封入方法であって、次のステップ:
ベース部とキャップ部を有する第1のカプセルを提供するステップ;
ベース部とキャップ部を有する第2のカプセルを提供するステップ;
第2のカプセル中に第1の物理的状態を示す少なくとも1種の成分を導入するステップであって、但し第2のカプセル中に導入される該成分がニュートラシューティカル、ビタミン、栄養補助食品、およびミネラルからなる群から選択される、該ステップ;
第2のカプセルのキャップ部を、ベース部と密封関係になるように配置するステップ;
第1のカプセル中に第2の物理的状態を示す少なくとも1種の成分を導入するステップであって、但し第1のカプセル中に導入される該成分はニュートラシューティカル、ビタミン、栄養補助食品、およびミネラルからなる群から選択され、第2のカプセルの該成分の第1の物理的状態は第1のカプセルの該成分の第2の物理的状態とは異なり、第2のカプセルの該成分は第1のカプセルの該成分とは異なる、該ステップ;
第1のカプセルのベース部内に第2のカプセルを導入するステップ;および
第1のカプセルのキャップ部を、ベース部と密封関係になるように配置するステップ;
を含んでなる前記方法。
An encapsulation method for forming a multi-compartment capsule comprising the following steps:
Providing a first capsule having a base portion and a cap portion;
Providing a second capsule having a base portion and a cap portion;
Introducing into the second capsule at least one ingredient exhibiting a first physical state, wherein the ingredient introduced into the second capsule is a nutraceutical, vitamin, dietary supplement, And the step selected from the group consisting of and minerals;
Placing the cap portion of the second capsule in a sealing relationship with the base portion;
Introducing at least one ingredient exhibiting a second physical state into the first capsule, wherein the ingredient introduced into the first capsule comprises a nutraceutical, a vitamin, a dietary supplement, And the first physical state of the component of the second capsule is different from the second physical state of the component of the first capsule, and the component of the second capsule is Different from the component of the first capsule, the step;
Introducing a second capsule into the base portion of the first capsule; and positioning the cap portion of the first capsule in a sealing relationship with the base portion;
Said method comprising.
次のステップ:
ベース部およびキャップ部を有する第3のカプセルを提供するステップ;
第3のカプセル中に第3の物理的状態を示す少なくとも1種の成分を導入するステップ;
第2のカプセルのキャップ部を、ベース部と密封関係になるように配置するステップ;および
第2のカプセルのベース部内に、第3のカプセルを導入するステップ;
をさらに含んでなる、請求項1に記載のカプセル封入方法。
Next steps:
Providing a third capsule having a base portion and a cap portion;
Introducing into the third capsule at least one component exhibiting a third physical state;
Placing the cap portion of the second capsule in a sealing relationship with the base portion; and introducing a third capsule into the base portion of the second capsule;
The encapsulation method according to claim 1, further comprising:
第1のカプセル中に導入される前記成分が約0重量%〜6重量%の範囲の含水量を含んでなる、請求項1または2に記載のカプセル封入方法。   The encapsulation method according to claim 1 or 2, wherein the component introduced into the first capsule comprises a water content ranging from about 0% to 6% by weight. 複数コンパートメントカプセルを形成するためのカプセル封入方法であって、次のステップ:
キャップ部、ある長さを有する長軸方向に延長されたボディーを有する形状になっているベース部、およびその延長されたボディーの該長さに沿って形成された少なくとも1つの隔壁を含み、但し該隔壁が第1の収容チャンバーおよび第2の収容チャンバーを形成するように適合させたものであるカプセルを、提供するステップ;
第2の収容チャンバー中に、第1の物理的状態を示す少なくとも1種の成分を導入するステップであって、但しカプセル中に導入される該成分がニュートラシューティカル、ビタミン、栄養補助食品、およびミネラルからなる群から選択される、該ステップ;
第1の収容チャンバー中に、第2の物理的状態を示す少なくとも1種の成分を導入するステップであって、但しカプセル中に導入される該成分がニュートラシューティカル、ビタミン、栄養補助食品、およびミネラルからなる群から選択され、第2の収容チャンバーの該成分の第1の物理的状態が第1の収容チャンバーの該成分の第2の物理的状態とは異なり、第2の収容チャンバーの該成分が第1の収容チャンバーの該成分とは異なる、該ステップ;および
キャップ部を、ベース部と密封関係になるように配置するステップ;
を含んでなる、前記カプセル封入方法。
An encapsulation method for forming a multi-compartment capsule comprising the following steps:
A cap portion, a base portion shaped to have a longitudinally extending body having a length, and at least one partition formed along the length of the extended body, wherein Providing a capsule wherein the septum is adapted to form a first containment chamber and a second containment chamber;
Introducing into the second containment chamber at least one component exhibiting a first physical state, wherein the component introduced into the capsule is nutraceutical, vitamin, dietary supplement, and The step selected from the group consisting of minerals;
Introducing into the first containment chamber at least one component exhibiting a second physical state, wherein the component introduced into the capsule is a nutraceutical, vitamin, dietary supplement, and Selected from the group consisting of minerals, wherein the first physical state of the component of the second containment chamber is different from the second physical state of the component of the first containment chamber; The component is different from the component of the first containment chamber; and placing the cap portion in a sealing relationship with the base portion;
The encapsulation method comprising:
第1の物理的状態を示す少なくとも1種の成分を含む第1の収容チャンバーと、
第2の物理的状態を示す少なくとも1種の成分を含む第2の収容チャンバーと、
を含む複数コンパートメントカプセルであって、第1の収容チャンバーの該成分の第1の物理的状態が第2の収容チャンバーの該成分の第2の物理的状態とは異なり、かつ、第1の収容チャンバーの該成分が第2の収容チャンバーの該成分とは異なる、前記複数コンパートメントカプセル。
A first containment chamber comprising at least one component exhibiting a first physical state;
A second containment chamber comprising at least one component exhibiting a second physical state;
A first compartment containing a first physical state of the component of the first containment chamber different from a second physical state of the component of the second containment chamber. The multi-compartment capsule wherein the component of the chamber is different from the component of the second containment chamber.
ベース部および対応するキャップ部をさらに含んでなり、キャップ部が、ベース部とかみ合ったときに密封関係を生じる形状になっている、請求項5に記載の複数コンパートメントカプセル。   The multi-compartment capsule of claim 5, further comprising a base portion and a corresponding cap portion, wherein the cap portion is shaped to create a sealing relationship when engaged with the base portion. キャップ部が、第1の収容チャンバー内のデッドスペース体積を低減する形状になっている、請求項6に記載の複数コンパートメントカプセル。   The multi-compartment capsule of claim 6, wherein the cap portion is shaped to reduce a dead space volume in the first storage chamber. 第1の収容チャンバー中の前記成分が、医薬品、バイオ技術品、ニュートラシューティカル、ビタミン、栄養補助食品、およびミネラルからなる群から選択され、かつ第2の収容チャンバー中の前記成分が、医薬品、バイオ技術品、ニュートラシューティカル、ビタミン、栄養補助食品、およびミネラルからなる群から選択される、請求項5に記載の複数コンパートメントカプセル。   The ingredient in the first containment chamber is selected from the group consisting of pharmaceuticals, biotech, nutraceuticals, vitamins, dietary supplements, and minerals, and the ingredients in the second containment chamber are pharmaceuticals, The multi-compartment capsule of claim 5, selected from the group consisting of biotech, nutraceuticals, vitamins, dietary supplements, and minerals. 第1の収容チャンバー中の前記成分が医薬品を含んでなり、第2の収容チャンバー中の前記成分がニュートラシューティカル、または栄養補助食品、またはミネラルを含んでなる、請求項5に記載の複数コンパートメントカプセル。   6. The multi-compartment of claim 5, wherein the component in the first containment chamber comprises a pharmaceutical and the component in the second containment chamber comprises a nutraceutical, or dietary supplement, or mineral. capsule. 第1の収容チャンバー中の前記成分の物理的状態が、固体、液体、気体、および分散体からなる群から選択される、請求項5に記載の複数コンパートメントカプセル。   The multi-compartment capsule of claim 5, wherein the physical state of the component in the first containment chamber is selected from the group consisting of a solid, a liquid, a gas, and a dispersion.
JP2003583294A 2002-04-10 2003-04-09 Multiphase, multiple compartment capsule system Pending JP2005528383A (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US37144802P 2002-04-10 2002-04-10
US10/369,247 US20030194430A1 (en) 2002-04-10 2003-02-18 Process for encapsulating multi-phase, multi-compartment capsules for therapeutic compositions
US10/369,244 US20030194429A1 (en) 2002-04-10 2003-02-18 Multi-phase, multi-compartment capsular delivery apparatus for therapeutic compositions and methods for using same
US10/368,951 US20030194428A1 (en) 2002-04-10 2003-02-18 Process for encapsulating multi-phase, multi-compartment capsules
US10/369,427 US20030194431A1 (en) 2002-04-10 2003-02-18 Multi-phase,multi-compartment capsular delivery apparatus and methods for using same
PCT/US2003/010816 WO2003086267A2 (en) 2002-04-10 2003-04-09 Multi-phase, multi-compartment capsular system

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2010264794A Division JP2011068664A (en) 2002-04-10 2010-11-29 Multi-phase, multi-compartment capsule system

Publications (2)

Publication Number Publication Date
JP2005528383A JP2005528383A (en) 2005-09-22
JP2005528383A5 true JP2005528383A5 (en) 2006-06-15

Family

ID=29255682

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2003583294A Pending JP2005528383A (en) 2002-04-10 2003-04-09 Multiphase, multiple compartment capsule system
JP2010264794A Pending JP2011068664A (en) 2002-04-10 2010-11-29 Multi-phase, multi-compartment capsule system

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2010264794A Pending JP2011068664A (en) 2002-04-10 2010-11-29 Multi-phase, multi-compartment capsule system

Country Status (6)

Country Link
EP (1) EP1499303A4 (en)
JP (2) JP2005528383A (en)
AU (3) AU2003220689A1 (en)
CA (1) CA2481486C (en)
NZ (1) NZ536267A (en)
WO (1) WO2003086267A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7229012B2 (en) 2018-12-25 2023-02-27 小林製薬株式会社 Pharmaceutical composition for internal use

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100710118B1 (en) 1999-07-30 2007-04-23 스미스클라인비이참피이엘시이 Multi-component pharmaceutical dosage form
US20040087527A1 (en) * 2002-10-31 2004-05-06 Day Brian J. Methods for treatment of thiol-containing compound deficient conditions
US7790762B2 (en) 2002-10-31 2010-09-07 National Jewish Health Compounds and methods for thiol-containing compound efflux and cancer treatment
DE10359792A1 (en) * 2003-12-19 2005-07-21 Bayer Technology Services Gmbh Multiphasic drug formulation
JP4963670B2 (en) * 2004-04-07 2012-06-27 レスベラトロル パートナーズ, エルエルシー Nutritional supplements and methods for processing them
JP5258297B2 (en) 2004-11-19 2013-08-07 グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー Custom-made dispensing of variable dose drug combination products to tailor therapy to individual
US7981908B2 (en) * 2005-05-11 2011-07-19 Vecta, Ltd. Compositions and methods for inhibiting gastric acid secretion
US7803817B2 (en) 2005-05-11 2010-09-28 Vecta, Ltd. Composition and methods for inhibiting gastric acid secretion
JP2006321730A (en) * 2005-05-17 2006-11-30 Maruzen Pharmaceut Co Ltd Antioxidant, antiaging agent, skin cosmetics, and food or drink
US7781572B2 (en) * 2005-10-05 2010-08-24 Nse Products, Inc. Nanosized carotenoid cyclodextrin complexes
DK3095447T3 (en) 2006-02-03 2022-01-31 Opko Renal Llc TREATMENT OF VITAMIN D INSUFFICIENTS AND DEFICIENCY WITH 25-HYDROXYVITAMIN D2 AND 25-HYDROXYVITAMIN D3
HUE037309T2 (en) 2006-06-21 2018-08-28 Opko Ireland Global Holdings Ltd Therapy using vitamin D repletion agent and vitamin D hormone replacement agent
WO2008012621A2 (en) 2006-07-25 2008-01-31 Vecta, Ltd. Compositions and meth0ds for inhibiting gastric acide secretion using derivatives of small dicarboxylic acids in combination with ppi
US20130115320A1 (en) 2007-03-30 2013-05-09 Dynova Laboratories, Inc. Therapeutic agent for intranasal administration and method of making and using same
KR20190028822A (en) 2007-04-25 2019-03-19 사이토크로마 인코포레이티드 Oral controlled release compositions comprising vitamin d compound and waxy carrier
CN104257667B (en) 2007-04-25 2019-06-04 欧普科Ip 控股Ii 有限公司 Treat vitamin d insufficiency and shortage, secondary hyperparathyroidism and vitamin D-responsive diseases method and composition
US7867524B2 (en) 2007-10-05 2011-01-11 David Rowland Energizing formulation
WO2010122499A2 (en) * 2009-04-20 2010-10-28 Ecole Polytechnique Federale De Lausanne (Epfl) Containers assembled in fluid and corresponding production
KR101143997B1 (en) * 2010-03-04 2012-05-09 한미사이언스 주식회사 Complex formulation for oral administration comprising probiotic formulation and 5-ht4 receptor agonist and method for the preparation thereof
WO2011123476A1 (en) 2010-03-29 2011-10-06 Cytochroma Inc. Methods and compositions for reducing parathyroid levels
CA3065589C (en) 2010-06-03 2022-04-26 Catalent Ontario Limited Multi phase soft gel capsules, apparatus and method thereof
US8967989B2 (en) * 2010-07-19 2015-03-03 Procaps SAS Apparatus and process for encapsulating capsules or other solid dosage forms within capsules
US20120082719A1 (en) * 2010-10-05 2012-04-05 Sam Poon Ang Compositions For Treating Chronic Viral Infections
CN102335095A (en) * 2011-10-12 2012-02-01 李思思 Manufacturing technology of d-limonene hard capsules
KR101847947B1 (en) 2013-03-15 2018-05-28 옵코 아이피 홀딩스 Ⅱ 인코포레이티드 Stabilized modified release vitamin d formulation
US10130760B2 (en) 2013-03-15 2018-11-20 Incube Labs, Llc Multi-stage biodegradable drug delivery platform
EP3193925A2 (en) 2014-08-07 2017-07-26 OPKO Ireland Global Holdings, Ltd. Adjunctive therapy with 25-hydroxyvitamin d
US9980993B2 (en) 2014-11-06 2018-05-29 NWO Stem Cure, LLC Nutraceutical supplement with Lactobacillus rhamnosus
US9468659B2 (en) 2014-11-06 2016-10-18 NWO Stem Cure, LLC Nutraceutical supplement with Lactobacillus rhamnosus
KR20230054752A (en) 2016-03-28 2023-04-25 옵코 아일랜드 글로벌 홀딩스 리미티드 Methods of vitamin d treatment
CN108753621A (en) * 2018-05-30 2018-11-06 昆明理工大学 A method of based on molasses give up mash improve single needle algae oil and fat accumulation
IT201900025063A1 (en) * 2019-12-20 2021-06-20 Idi Integratori Dietetici Italiani S R L GASTRORESISTANT COMPOSITIONS INCLUDING INOSITOL AND / OR SYLVESTRE GYMNEMA EXTRACT, THEIR PHARMACEUTICAL AND NUTRACEUTICAL COMPOSITIONS AND THEIR USE
CN116648239A (en) * 2021-08-26 2023-08-25 宁德时代新能源科技股份有限公司 Liquid bag, battery monomer, battery and electricity utilization device

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2729068A1 (en) * 1977-06-28 1979-01-11 Rainer Dr Med Liedtke Releasing incompatible pharmaceuticals from capsules - by including a second capsule inside the first
US4185740A (en) * 1978-08-02 1980-01-29 Johnson & Johnson Disposable capsules
CH661878A5 (en) * 1983-11-04 1987-08-31 Warner Lambert Co CAPSULE DOSING FORMS.
JPS6342094Y2 (en) * 1985-07-02 1988-11-04
DE3543154A1 (en) * 1985-12-06 1987-06-11 Boehringer Ingelheim Kg DIVISIBLE CAPSULE
US4940499A (en) * 1989-05-23 1990-07-10 Warner-Lambert Company Method and apparatus for sealing capsules containing medicaments
DK0487575T3 (en) * 1989-08-17 1994-11-28 Cortecs Ltd Pharmaceutical formulations
US5501857A (en) * 1992-07-24 1996-03-26 Midwestern Bio-Ag Products & Services, Inc. Oral nutritional and dietary composition
JPH06316517A (en) * 1993-02-22 1994-11-15 Grelan Pharmaceut Co Ltd Sustained-release preparation
JP2000239159A (en) * 1999-02-19 2000-09-05 Nitto Yakuhin Kogyo Kk Capsule preparation and it production
AR031068A1 (en) * 1999-04-13 2003-09-10 Beecham Pharm Pte Ltd A PHARMACEUTICAL FORMULATION OF MODIFIED RELEASE THAT INCLUDES AMOXICILLIN AND POTASSIUM CLAVULANATE IN A RATIO OF 2: 1 TO 20: 1, A COMPRESSED IN LAYERS, THE USE OF AMOXYCLINE AND THE POTASSIUM CLAVULANATE FOR THE MANUFACTURE OF A MEDICINAL PRODUCT COMPACT GRANULES
EP1647494A3 (en) * 1999-11-17 2015-09-23 Reckitt Benckiser (UK) Limited Injection moulded water-soluble container
US6372252B1 (en) * 2000-04-28 2002-04-16 Adams Laboratories, Inc. Guaifenesin sustained release formulation and tablets
DE60126089T2 (en) * 2000-07-20 2007-11-08 MW Encap Ltd., Livingston ADMINISTRATION SYSTEM

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7229012B2 (en) 2018-12-25 2023-02-27 小林製薬株式会社 Pharmaceutical composition for internal use

Similar Documents

Publication Publication Date Title
JP2005528383A5 (en)
US10166193B2 (en) Method of making a soft gel capsule comprising CoQ-10 solubilized in a monoterpene
KR101190791B1 (en) Compositions and methods for the sustained release of beta-alanine
CA2481486A1 (en) Multi-phase, multi-compartment capsular system
US20030104048A1 (en) Pharmaceutical dosage forms for highly hydrophilic materials
CN101861144B (en) Lipoic acid pellet composition
JP2007537258A5 (en)
WO2007109824A1 (en) Stable packaged dosage form and process therefor
JP2000086505A5 (en)
AU2005227118A1 (en) Solubilized CoQ-10 and carnitine
US20090155355A1 (en) Particles in a capsule
CN101721708B (en) ED-71 preparation
US20210015776A1 (en) Methods of stabilization of levothyroxine sodium tablets
US20200383903A1 (en) Supplements composition with effervescent agent
WO2005100384A3 (en) Ai-2 compounds and analogs based on salmonella typhimurium lsrb structure
KR102345154B1 (en) Multi-Filled/Chamber Softgel Dies
JP2021168708A (en) Dried anchovy powder and fructan-powder containing nutritional supplementary food
CN101033030B (en) Application of nontoxic composite aluminum foil for exterior package of PVC or non-PVC soft packed transfusion agent
WO2008113368A1 (en) A gelatin capsule with extra cap for combined therapies
KR20220124224A (en) oral composition
CN105560054A (en) Obstacle type pill package preventing pills from being taken by children by mistake
JP2004026844A5 (en)
CN205145146U (en) Acidproof membrane clothing capsule structure
CN2290567Y (en) Integral multi-layer packing bottle
CN209192655U (en) A kind of aluminum-plastic bubble-cap palte of high stability