JP2005526695A5 - - Google Patents

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Publication number
JP2005526695A5
JP2005526695A5 JP2003526388A JP2003526388A JP2005526695A5 JP 2005526695 A5 JP2005526695 A5 JP 2005526695A5 JP 2003526388 A JP2003526388 A JP 2003526388A JP 2003526388 A JP2003526388 A JP 2003526388A JP 2005526695 A5 JP2005526695 A5 JP 2005526695A5
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JP
Japan
Prior art keywords
compound
stereoisomers
stereoisomer
substantially free
less
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2003526388A
Other languages
English (en)
Japanese (ja)
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JP2005526695A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2002/029014 external-priority patent/WO2003022259A1/en
Publication of JP2005526695A publication Critical patent/JP2005526695A/ja
Publication of JP2005526695A5 publication Critical patent/JP2005526695A5/ja
Pending legal-status Critical Current

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JP2003526388A 2001-09-13 2002-09-12 シブトラミンおよびそれの代謝物の2−ヒドロキシ誘導体の製造方法および使用方法 Pending JP2005526695A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US31867201P 2001-09-13 2001-09-13
US32519201P 2001-09-28 2001-09-28
PCT/US2002/029014 WO2003022259A1 (en) 2001-09-13 2002-09-12 Methods of preparing and using 2-hydroxy derivatives of sibutramine and its metabolites

Publications (2)

Publication Number Publication Date
JP2005526695A JP2005526695A (ja) 2005-09-08
JP2005526695A5 true JP2005526695A5 (https=) 2009-01-22

Family

ID=26981614

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2003526388A Pending JP2005526695A (ja) 2001-09-13 2002-09-12 シブトラミンおよびそれの代謝物の2−ヒドロキシ誘導体の製造方法および使用方法

Country Status (6)

Country Link
US (1) US20030087963A1 (https=)
EP (1) EP1434575A4 (https=)
JP (1) JP2005526695A (https=)
AU (1) AU2002326883B2 (https=)
CA (1) CA2460348A1 (https=)
WO (1) WO2003022259A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8821915B2 (en) 2002-08-09 2014-09-02 Veroscience, Llc Therapeutic process for the treatment of the metabolic syndrome and associated metabolic disorders
US20070032554A1 (en) * 2003-08-27 2007-02-08 Elililly And Company A Corporation Treatment of stuttering and other communication disorders with norepinephrine reuptake inhibitors
WO2005072715A1 (en) * 2004-01-29 2005-08-11 Sepracor Inc. Use of (s)-didesmethylsibutraminefor treating, preventing and managing a sleep disorder
DK1742624T3 (da) * 2004-02-18 2010-03-08 Sepracor Inc Dopamin-agonist-kombinationsterapi med sedativer til forbedring af søvnkvalitet
CA2663254C (en) 2006-09-15 2016-04-19 Reviva Pharmaceuticals, Inc. Synthesis, methods of using, and compositions of cycloalkylmethylamines
EP3524248A1 (en) 2007-06-21 2019-08-14 VeroScience LLC Method of treating metabolic disorders and depression with dopamine receptor agonists
US9352025B2 (en) 2009-06-05 2016-05-31 Veroscience Llc Combination of dopamine agonists plus first phase insulin secretagogues for the treatment of metabolic disorders
WO2012003501A2 (en) 2010-07-02 2012-01-05 Reviva Pharmaceuticals, Inc. Compositions, synthesis, and methods of using cycloalkylmethylamine derivatives

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US3155670A (en) 1962-06-22 1964-11-03 Res Lab Dr C Janssen N V 1-oxo-2, 4, 8, triaza-spiro (4, 5) decanes
US3155669A (en) 1962-06-22 1964-11-03 Res Lab Dr C Janssen N V 2, 4, 8-triaza-spiro (4, 5) dec-2-enes
US3471515A (en) 1965-02-01 1969-10-07 Sandoz Ag (2-hydroxy-3-substituted aminopropoxy)indoles
US3466325A (en) 1965-04-30 1969-09-09 Haessle Ab 1-(ortho-alkenyl phenoxy) - 2-hydroxy-3-isopropylaminopropanes and the salts thereof
US3536809A (en) 1969-02-17 1970-10-27 Alza Corp Medication method
US3598123A (en) 1969-04-01 1971-08-10 Alza Corp Bandage for administering drugs
GB1308191A (en) 1970-04-06 1973-02-21 Science Union & Cie Thiochroman derivatives and a process for preparing them
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IE58110B1 (en) 1984-10-30 1993-07-14 Elan Corp Plc Controlled release powder and process for its preparation
GB8501192D0 (en) * 1985-01-17 1985-02-20 Boots Co Plc Therapeutic agents
US5073543A (en) 1988-07-21 1991-12-17 G. D. Searle & Co. Controlled release formulations of trophic factors in ganglioside-lipsome vehicle
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IT1229203B (it) 1989-03-22 1991-07-25 Bioresearch Spa Impiego di acido 5 metiltetraidrofolico, di acido 5 formiltetraidrofolico e dei loro sali farmaceuticamente accettabili per la preparazione di composizioni farmaceutiche in forma a rilascio controllato attive nella terapia dei disturbi mentali organici e composizioni farmaceutiche relative.
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IT1270594B (it) 1994-07-07 1997-05-07 Recordati Chem Pharm Composizione farmaceutica a rilascio controllato di moguisteina in sospensione liquida
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