JP2005522579A - 医療用デバイスにおいて使用するための、ポリシロキサンベースのポリマー組成物の生成のための改善されたプロセス - Google Patents
医療用デバイスにおいて使用するための、ポリシロキサンベースのポリマー組成物の生成のための改善されたプロセス Download PDFInfo
- Publication number
- JP2005522579A JP2005522579A JP2004519527A JP2004519527A JP2005522579A JP 2005522579 A JP2005522579 A JP 2005522579A JP 2004519527 A JP2004519527 A JP 2004519527A JP 2004519527 A JP2004519527 A JP 2004519527A JP 2005522579 A JP2005522579 A JP 2005522579A
- Authority
- JP
- Japan
- Prior art keywords
- group
- polysiloxane
- polymer composition
- same
- different
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
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- 239000000203 mixture Substances 0.000 title claims abstract description 62
- 238000000034 method Methods 0.000 title claims abstract description 58
- -1 polysiloxane Polymers 0.000 title claims abstract description 58
- 229920001296 polysiloxane Polymers 0.000 title claims abstract description 57
- 229920000642 polymer Polymers 0.000 title claims abstract description 56
- 238000004519 manufacturing process Methods 0.000 title claims abstract description 25
- 210000004087 cornea Anatomy 0.000 claims abstract description 6
- 238000007334 copolymerization reaction Methods 0.000 claims abstract description 5
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims description 11
- 230000003014 reinforcing effect Effects 0.000 claims description 11
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 claims description 11
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 10
- KPUWHANPEXNPJT-UHFFFAOYSA-N disiloxane Chemical class [SiH3]O[SiH3] KPUWHANPEXNPJT-UHFFFAOYSA-N 0.000 claims description 8
- 229910000077 silane Inorganic materials 0.000 claims description 7
- 239000000945 filler Substances 0.000 claims description 6
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims description 5
- 239000000377 silicon dioxide Substances 0.000 claims description 5
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims description 3
- 229910052739 hydrogen Inorganic materials 0.000 claims description 3
- 239000001257 hydrogen Substances 0.000 claims description 3
- 150000004756 silanes Chemical class 0.000 claims 4
- 238000005266 casting Methods 0.000 claims 2
- 238000003754 machining Methods 0.000 claims 2
- 230000000379 polymerizing effect Effects 0.000 claims 2
- 229920002100 high-refractive-index polymer Polymers 0.000 abstract 1
- 239000000047 product Substances 0.000 description 18
- KAKZBPTYRLMSJV-UHFFFAOYSA-N Butadiene Chemical group C=CC=C KAKZBPTYRLMSJV-UHFFFAOYSA-N 0.000 description 12
- 229920002379 silicone rubber Polymers 0.000 description 9
- 125000004122 cyclic group Chemical group 0.000 description 8
- 125000003118 aryl group Chemical group 0.000 description 7
- 238000006116 polymerization reaction Methods 0.000 description 7
- 239000007943 implant Substances 0.000 description 6
- 239000000463 material Substances 0.000 description 6
- 230000003287 optical effect Effects 0.000 description 6
- 230000000704 physical effect Effects 0.000 description 5
- 238000000746 purification Methods 0.000 description 5
- 238000001542 size-exclusion chromatography Methods 0.000 description 5
- 208000002177 Cataract Diseases 0.000 description 4
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 4
- 208000002847 Surgical Wound Diseases 0.000 description 4
- 239000006227 byproduct Substances 0.000 description 4
- 239000002775 capsule Substances 0.000 description 4
- 238000002360 preparation method Methods 0.000 description 4
- 239000012744 reinforcing agent Substances 0.000 description 4
- 238000001356 surgical procedure Methods 0.000 description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 4
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 3
- 210000002159 anterior chamber Anatomy 0.000 description 3
- 239000003054 catalyst Substances 0.000 description 3
- 239000013078 crystal Substances 0.000 description 3
- 230000007547 defect Effects 0.000 description 3
- 238000013461 design Methods 0.000 description 3
- 125000002347 octyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 3
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 description 3
- 229920002554 vinyl polymer Polymers 0.000 description 3
- CSNNHWWHGAXBCP-UHFFFAOYSA-L Magnesium sulfate Chemical compound [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 description 2
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 description 2
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 2
- 229910052782 aluminium Inorganic materials 0.000 description 2
- QRUDEWIWKLJBPS-UHFFFAOYSA-N benzotriazole Chemical compound C1=CC=C2N[N][N]C2=C1 QRUDEWIWKLJBPS-UHFFFAOYSA-N 0.000 description 2
- 239000012964 benzotriazole Substances 0.000 description 2
- 229920000249 biocompatible polymer Polymers 0.000 description 2
- 235000010290 biphenyl Nutrition 0.000 description 2
- 239000004305 biphenyl Substances 0.000 description 2
- 125000006267 biphenyl group Chemical group 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 230000001886 ciliary effect Effects 0.000 description 2
- 239000000356 contaminant Substances 0.000 description 2
- 125000000118 dimethyl group Chemical group [H]C([H])([H])* 0.000 description 2
- 230000004438 eyesight Effects 0.000 description 2
- 239000010408 film Substances 0.000 description 2
- 239000011888 foil Substances 0.000 description 2
- 238000002513 implantation Methods 0.000 description 2
- 238000003780 insertion Methods 0.000 description 2
- 230000037431 insertion Effects 0.000 description 2
- 239000000178 monomer Substances 0.000 description 2
- 238000000465 moulding Methods 0.000 description 2
- 125000001624 naphthyl group Chemical group 0.000 description 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 2
- ZUOUZKKEUPVFJK-UHFFFAOYSA-N phenylbenzene Natural products C1=CC=CC=C1C1=CC=CC=C1 ZUOUZKKEUPVFJK-UHFFFAOYSA-N 0.000 description 2
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 2
- 229920003229 poly(methyl methacrylate) Polymers 0.000 description 2
- 239000004926 polymethyl methacrylate Substances 0.000 description 2
- 239000011347 resin Substances 0.000 description 2
- 229920005989 resin Polymers 0.000 description 2
- 239000002904 solvent Substances 0.000 description 2
- 239000010409 thin film Substances 0.000 description 2
- 229940124543 ultraviolet light absorber Drugs 0.000 description 2
- VSIKJPJINIDELZ-UHFFFAOYSA-N 2,2,4,4,6,6,8,8-octakis-phenyl-1,3,5,7,2,4,6,8-tetraoxatetrasilocane Chemical compound O1[Si](C=2C=CC=CC=2)(C=2C=CC=CC=2)O[Si](C=2C=CC=CC=2)(C=2C=CC=CC=2)O[Si](C=2C=CC=CC=2)(C=2C=CC=CC=2)O[Si]1(C=1C=CC=CC=1)C1=CC=CC=C1 VSIKJPJINIDELZ-UHFFFAOYSA-N 0.000 description 1
- DNPYHJOJVAOLLZ-UHFFFAOYSA-N 2-tert-butyl-6-(5-methoxybenzotriazol-2-yl)-4-[3-(2-methylprop-1-enylsilyl)propoxy]phenol Chemical compound N1=C2C=C(OC)C=CC2=NN1C1=CC(OCCC[SiH2]C=C(C)C)=CC(C(C)(C)C)=C1O DNPYHJOJVAOLLZ-UHFFFAOYSA-N 0.000 description 1
- 206010002945 Aphakia Diseases 0.000 description 1
- 208000035965 Postoperative Complications Diseases 0.000 description 1
- 239000004111 Potassium silicate Substances 0.000 description 1
- BLRPTPMANUNPDV-UHFFFAOYSA-N Silane Chemical compound [SiH4] BLRPTPMANUNPDV-UHFFFAOYSA-N 0.000 description 1
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 1
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical class [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 1
- 229910000831 Steel Inorganic materials 0.000 description 1
- 230000004308 accommodation Effects 0.000 description 1
- 238000004026 adhesive bonding Methods 0.000 description 1
- 125000000217 alkyl group Chemical group 0.000 description 1
- 150000001412 amines Chemical class 0.000 description 1
- 201000009310 astigmatism Diseases 0.000 description 1
- 239000007795 chemical reaction product Substances 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 229920001577 copolymer Polymers 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- JJQZDUKDJDQPMQ-UHFFFAOYSA-N dimethoxy(dimethyl)silane Chemical compound CO[Si](C)(C)OC JJQZDUKDJDQPMQ-UHFFFAOYSA-N 0.000 description 1
- AHUXYBVKTIBBJW-UHFFFAOYSA-N dimethoxy(diphenyl)silane Chemical compound C=1C=CC=CC=1[Si](OC)(OC)C1=CC=CC=C1 AHUXYBVKTIBBJW-UHFFFAOYSA-N 0.000 description 1
- 229920001971 elastomer Polymers 0.000 description 1
- 239000000806 elastomer Substances 0.000 description 1
- BITPLIXHRASDQB-UHFFFAOYSA-N ethenyl-[ethenyl(dimethyl)silyl]oxy-dimethylsilane Chemical compound C=C[Si](C)(C)O[Si](C)(C)C=C BITPLIXHRASDQB-UHFFFAOYSA-N 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 125000000524 functional group Chemical group 0.000 description 1
- 230000009477 glass transition Effects 0.000 description 1
- NYMPGSQKHIOWIO-UHFFFAOYSA-N hydroxy(diphenyl)silicon Chemical class C=1C=CC=CC=1[Si](O)C1=CC=CC=C1 NYMPGSQKHIOWIO-UHFFFAOYSA-N 0.000 description 1
- 230000000977 initiatory effect Effects 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 229910052943 magnesium sulfate Inorganic materials 0.000 description 1
- 235000019341 magnesium sulphate Nutrition 0.000 description 1
- 238000002844 melting Methods 0.000 description 1
- 230000008018 melting Effects 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- HMMGMWAXVFQUOA-UHFFFAOYSA-N octamethylcyclotetrasiloxane Chemical compound C[Si]1(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O1 HMMGMWAXVFQUOA-UHFFFAOYSA-N 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 229910052697 platinum Inorganic materials 0.000 description 1
- 238000005498 polishing Methods 0.000 description 1
- NNHHDJVEYQHLHG-UHFFFAOYSA-N potassium silicate Chemical compound [K+].[K+].[O-][Si]([O-])=O NNHHDJVEYQHLHG-UHFFFAOYSA-N 0.000 description 1
- 229910052913 potassium silicate Inorganic materials 0.000 description 1
- 235000019353 potassium silicate Nutrition 0.000 description 1
- 210000001525 retina Anatomy 0.000 description 1
- 229910052710 silicon Inorganic materials 0.000 description 1
- 239000010703 silicon Substances 0.000 description 1
- 235000017557 sodium bicarbonate Nutrition 0.000 description 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 1
- 239000007779 soft material Substances 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 239000010959 steel Substances 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 230000002194 synthesizing effect Effects 0.000 description 1
- 230000008733 trauma Effects 0.000 description 1
- 239000006097 ultraviolet radiation absorber Substances 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G77/00—Macromolecular compounds obtained by reactions forming a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon in the main chain of the macromolecule
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G77/00—Macromolecular compounds obtained by reactions forming a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon in the main chain of the macromolecule
- C08G77/04—Polysiloxanes
- C08G77/32—Post-polymerisation treatment
- C08G77/34—Purification
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G77/00—Macromolecular compounds obtained by reactions forming a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon in the main chain of the macromolecule
- C08G77/04—Polysiloxanes
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G77/00—Macromolecular compounds obtained by reactions forming a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon in the main chain of the macromolecule
- C08G77/04—Polysiloxanes
- C08G77/20—Polysiloxanes containing silicon bound to unsaturated aliphatic groups
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B1/00—Optical elements characterised by the material of which they are made; Optical coatings for optical elements
- G02B1/04—Optical elements characterised by the material of which they are made; Optical coatings for optical elements made of organic materials, e.g. plastics
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B1/00—Optical elements characterised by the material of which they are made; Optical coatings for optical elements
- G02B1/04—Optical elements characterised by the material of which they are made; Optical coatings for optical elements made of organic materials, e.g. plastics
- G02B1/041—Lenses
- G02B1/043—Contact lenses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/16—Materials or treatment for tissue regeneration for reconstruction of eye parts, e.g. intraocular lens, cornea
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Dermatology (AREA)
- Transplantation (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Prostheses (AREA)
- Materials For Medical Uses (AREA)
- Silicon Polymers (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/103,260 US6805712B2 (en) | 2002-03-20 | 2002-03-20 | Process for the production of polysiloxane-based polymeric compositions for use in medical devices |
| PCT/US2003/008717 WO2004005375A1 (en) | 2002-03-20 | 2003-03-19 | Improved process for the production of polysiloxane-based polymeric compositions for use in medical devices |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005522579A true JP2005522579A (ja) | 2005-07-28 |
| JP2005522579A5 JP2005522579A5 (https=) | 2006-03-16 |
Family
ID=28040348
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004519527A Withdrawn JP2005522579A (ja) | 2002-03-20 | 2003-03-19 | 医療用デバイスにおいて使用するための、ポリシロキサンベースのポリマー組成物の生成のための改善されたプロセス |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6805712B2 (https=) |
| EP (1) | EP1485425B1 (https=) |
| JP (1) | JP2005522579A (https=) |
| KR (1) | KR20040099336A (https=) |
| CN (1) | CN1315914C (https=) |
| AR (1) | AR039034A1 (https=) |
| AT (1) | ATE328029T1 (https=) |
| AU (1) | AU2003274891A1 (https=) |
| CA (1) | CA2479239A1 (https=) |
| DE (1) | DE60305665T2 (https=) |
| ES (1) | ES2265585T3 (https=) |
| WO (1) | WO2004005375A1 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6956087B2 (en) * | 2002-12-13 | 2005-10-18 | Bausch & Lomb Incorporated | High refractive index polysiloxane prepolymers |
| US20060004165A1 (en) * | 2004-06-30 | 2006-01-05 | Phelan John C | Silicone hydrogels with lathability at room temperature |
| CN101163748B (zh) * | 2005-05-26 | 2011-04-13 | 陶氏康宁公司 | 用于模塑小的型材的方法和有机硅封装剂组合物 |
| KR101325792B1 (ko) * | 2006-01-17 | 2013-11-04 | 다우 코닝 코포레이션 | 열 안정성 투명 실리콘 수지 조성물 및 이의 제조 방법 및용도 |
| CN101336383B (zh) * | 2006-02-01 | 2012-05-09 | 陶氏康宁公司 | 抗冲击的光波导管及其制造方法 |
| WO2007100445A2 (en) * | 2006-02-24 | 2007-09-07 | Dow Corning Corporation | Light emitting device encapsulated with silicones and curable silicone compositions for preparing the silicones |
| US7468397B2 (en) * | 2006-06-30 | 2008-12-23 | Bausch & Lomb Incorporated | Polymerizable siloxane-quaternary amine copolymers |
| US8216310B2 (en) * | 2007-09-28 | 2012-07-10 | Abbott Medical Optics Inc. | Polymer compositions suitable for intraocular lenses and related methods |
| US8530590B2 (en) * | 2007-12-21 | 2013-09-10 | Abbot Medical Optics Inc. | Soft silicone materials for ophthalmic applications |
| US9156949B2 (en) | 2007-12-21 | 2015-10-13 | Abbott Medical Optics Inc. | Silicone containing polymeric materials |
| US8232363B2 (en) * | 2007-12-21 | 2012-07-31 | Abbott Medical Optics Inc. | Silicone containing polymeric materials |
| BRPI0808769A2 (pt) * | 2008-09-11 | 2014-08-12 | Lanxess Deutschland Gmbh | Adesivos hotmelt |
| EP3672523A4 (en) * | 2017-09-20 | 2021-05-19 | Clearsight, LLC | ONE-PIECE INTRAOCULAR LENSES AND METHOD OF MANUFACTURING THEREOF |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4304895A (en) * | 1973-06-20 | 1981-12-08 | Wesley-Jessen, Inc. | Ultraviolet absorbing corneal contact lenses |
| US4154714A (en) * | 1975-03-05 | 1979-05-15 | Wacker-Chemie Gmbh | Adhesive repellent coatings and substrates coated therewith |
| US3996189A (en) | 1975-04-29 | 1976-12-07 | American Optical Corporation | Optically clear filled silicone elastomers |
| US3996187A (en) | 1975-04-29 | 1976-12-07 | American Optical Corporation | Optically clear filled silicone elastomers |
| JPS5239751A (en) * | 1975-09-26 | 1977-03-28 | Shin Etsu Chem Co Ltd | Curable organopolysiloxane compositions |
| GB1588963A (en) * | 1976-07-28 | 1981-05-07 | Nat Res Dev | Stone treatment |
| JPS6033777B2 (ja) * | 1979-03-28 | 1985-08-05 | ト−レ・シリコ−ン株式会社 | 光通信ガラスファイバ用被覆剤 |
| US4418165A (en) | 1980-06-03 | 1983-11-29 | Dow Corning Corporation | Optically clear silicone compositions curable to elastomers |
| US4647282A (en) | 1985-08-27 | 1987-03-03 | Moskovsky Nauchno-Issledovatelsky Institut Mikrokhirurgii Glaza | Material for ocular prosthetics |
| US4868251A (en) | 1986-12-24 | 1989-09-19 | Allergan, Inc. | Ultraviolet light absorbing silicone compositions |
| US5236970A (en) * | 1987-02-05 | 1993-08-17 | Allergan, Inc. | Optically clear reinforced silicone elastomers of high optical refractive index and improved mechanical properties for use in intraocular lenses |
| US5512609A (en) | 1992-04-14 | 1996-04-30 | Allergan, Inc. | Reinforced compositions and lens bodies made from same |
| US5444106A (en) | 1992-04-21 | 1995-08-22 | Kabi Pharmacia Ophthalmics, Inc. | High refractive index silicone compositions |
| US5441690A (en) * | 1993-07-06 | 1995-08-15 | International Business Machines Corporation | Process of making pinless connector |
| US5739370A (en) * | 1997-04-02 | 1998-04-14 | General Electric Company | Process the production of octaphenylcyclotetrasiloxane |
| JP3283816B2 (ja) * | 1998-03-09 | 2002-05-20 | ホーヤ株式会社 | 眼内レンズ |
| US6121368A (en) * | 1999-09-07 | 2000-09-19 | Dow Corning Corporation | Silicone composition and silicone pressure sensitive adhesive formed therefrom |
| US6483981B1 (en) * | 2000-06-28 | 2002-11-19 | Molecular Optoelectronics Corp. | Single-channel attenuators |
| US6415093B1 (en) * | 2000-08-17 | 2002-07-02 | Nippon Sheet Glass Co., Ltd. | Optical device and adhesive composition used therefor |
| US20020074086A1 (en) * | 2000-09-29 | 2002-06-20 | Koichiro Nakamura | Adhesive composition and optical device using the same |
-
2002
- 2002-03-20 US US10/103,260 patent/US6805712B2/en not_active Expired - Fee Related
-
2003
- 2003-03-19 WO PCT/US2003/008717 patent/WO2004005375A1/en not_active Ceased
- 2003-03-19 CN CNB038065576A patent/CN1315914C/zh not_active Expired - Fee Related
- 2003-03-19 JP JP2004519527A patent/JP2005522579A/ja not_active Withdrawn
- 2003-03-19 CA CA002479239A patent/CA2479239A1/en not_active Abandoned
- 2003-03-19 AT AT03759171T patent/ATE328029T1/de not_active IP Right Cessation
- 2003-03-19 EP EP03759171A patent/EP1485425B1/en not_active Expired - Lifetime
- 2003-03-19 KR KR10-2004-7014629A patent/KR20040099336A/ko not_active Withdrawn
- 2003-03-19 AU AU2003274891A patent/AU2003274891A1/en not_active Abandoned
- 2003-03-19 DE DE60305665T patent/DE60305665T2/de not_active Expired - Lifetime
- 2003-03-19 ES ES03759171T patent/ES2265585T3/es not_active Expired - Lifetime
- 2003-03-20 AR ARP030100975A patent/AR039034A1/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AR039034A1 (es) | 2005-02-02 |
| CN1315914C (zh) | 2007-05-16 |
| CN1643033A (zh) | 2005-07-20 |
| EP1485425B1 (en) | 2006-05-31 |
| US6805712B2 (en) | 2004-10-19 |
| DE60305665T2 (de) | 2006-09-21 |
| EP1485425A1 (en) | 2004-12-15 |
| KR20040099336A (ko) | 2004-11-26 |
| HK1072949A1 (en) | 2005-09-16 |
| CA2479239A1 (en) | 2004-01-15 |
| ES2265585T3 (es) | 2007-02-16 |
| DE60305665D1 (de) | 2006-07-06 |
| WO2004005375A1 (en) | 2004-01-15 |
| ATE328029T1 (de) | 2006-06-15 |
| US20030181588A1 (en) | 2003-09-25 |
| AU2003274891A1 (en) | 2004-01-23 |
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