JP2005519123A - 組換え胞子 - Google Patents
組換え胞子 Download PDFInfo
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- JP2005519123A JP2005519123A JP2003573134A JP2003573134A JP2005519123A JP 2005519123 A JP2005519123 A JP 2005519123A JP 2003573134 A JP2003573134 A JP 2003573134A JP 2003573134 A JP2003573134 A JP 2003573134A JP 2005519123 A JP2005519123 A JP 2005519123A
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- NRHMKIHPTBHXPF-TUJRSCDTSA-M sodium cholate Chemical compound [Na+].C([C@H]1C[C@H]2O)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC([O-])=O)C)[C@@]2(C)[C@@H](O)C1 NRHMKIHPTBHXPF-TUJRSCDTSA-M 0.000 description 1
- FHHPUSMSKHSNKW-SMOYURAASA-M sodium deoxycholate Chemical compound [Na+].C([C@H]1CC2)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC([O-])=O)C)[C@@]2(C)[C@@H](O)C1 FHHPUSMSKHSNKW-SMOYURAASA-M 0.000 description 1
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- 101150117635 tetC gene Proteins 0.000 description 1
- 229940118376 tetanus toxin Drugs 0.000 description 1
- 229960002766 tetanus vaccines Drugs 0.000 description 1
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Images
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K39/08—Clostridium, e.g. Clostridium tetani
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- A—HUMAN NECESSITIES
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- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
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- A—HUMAN NECESSITIES
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- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0205376.7A GB0205376D0 (en) | 2002-03-07 | 2002-03-07 | Spore germination |
| PCT/GB2003/000966 WO2003074681A1 (en) | 2002-03-07 | 2003-03-07 | Recombinant spores |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005519123A true JP2005519123A (ja) | 2005-06-30 |
| JP2005519123A5 JP2005519123A5 (https=) | 2006-04-27 |
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| JP2003573134A Withdrawn JP2005519123A (ja) | 2002-03-07 | 2003-03-07 | 組換え胞子 |
Country Status (9)
| Country | Link |
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| US (1) | US20050287168A1 (https=) |
| EP (1) | EP1495110A1 (https=) |
| JP (1) | JP2005519123A (https=) |
| KR (1) | KR20040099293A (https=) |
| CN (1) | CN1639322A (https=) |
| AU (1) | AU2003214391A1 (https=) |
| GB (1) | GB0205376D0 (https=) |
| RU (1) | RU2004129739A (https=) |
| WO (1) | WO2003074681A1 (https=) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008231063A (ja) * | 2007-03-22 | 2008-10-02 | Takano Foods Kk | 納豆菌ワクチン |
| JPWO2011111783A1 (ja) * | 2010-03-12 | 2013-06-27 | カルピス株式会社 | 大腸におけるビフィズス菌の増加及び減少抑制剤 |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0503509D0 (en) * | 2005-02-19 | 2005-03-30 | New Royal Holloway & Bedford | An improved delivery agent |
| US9610333B2 (en) * | 2008-07-11 | 2017-04-04 | Tufts University | Methods, compositions and kits for vegetative cell-based vaccines and spore-based vaccines |
| WO2010006326A2 (en) * | 2008-07-11 | 2010-01-14 | Tufts University | Methods and compositions for spore-based vaccines |
| EP4077359B1 (en) | 2019-12-18 | 2026-03-18 | LivingMed Biotech S.R.L. | Genetically modified clostridium strains and uses thereof |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5668255A (en) * | 1984-06-07 | 1997-09-16 | Seragen, Inc. | Hybrid molecules having translocation region and cell-binding region |
| US5223409A (en) * | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| DE69002817T2 (de) * | 1989-11-28 | 1993-12-09 | Wellcome Found | Vakzine. |
| US6280721B1 (en) * | 1989-12-18 | 2001-08-28 | Valent Biosciences, Inc. | Production of Bacillus thuringiensis integrants |
| JP3415145B2 (ja) * | 1991-03-05 | 2003-06-09 | ザ ウエルカム ファウンデーション リミテッド | 弱毒化細菌における組換えタンパク質の発現 |
| US5340577A (en) * | 1992-07-29 | 1994-08-23 | The United States Of America, As Represented By The Secretary Of Agriculture | Probiotic for control of salmonella |
| GB9401787D0 (en) * | 1994-01-31 | 1994-03-23 | Medeva Holdings Bv | Vaccine compositions |
| GB9400650D0 (en) * | 1994-01-14 | 1994-03-09 | Smithkline Beecham Biolog | Expression of surface lazer proteins |
| US5533973A (en) * | 1995-01-13 | 1996-07-09 | Abbott Laboratories | Alteration of nutritional product during enteral tube feeding |
| US5531681A (en) * | 1995-01-13 | 1996-07-02 | Abbott Laboratories | Apparatus for altering composition of nutritional product during enteral tube feeding |
| US5531734A (en) * | 1995-01-13 | 1996-07-02 | Abbott Laboratories | Method of altering composition of nutritional product during enteral tube feeding |
| US5800821A (en) * | 1995-03-10 | 1998-09-01 | New England Medical Center Hospitals, Inc. | Bacterial spores as a heat stable vaccine delivery system |
| US5707353A (en) * | 1995-12-21 | 1998-01-13 | Abbott Laboratories | Oral administration of beneficial agents |
| WO1997035612A1 (fr) * | 1996-03-23 | 1997-10-02 | The Research Foundation For Microbial Diseases Of Osaka University | Antigene a fragment fonctionnel de la toxine du tetanos, et vaccin contre le tetanos |
| US5707127A (en) * | 1996-06-26 | 1998-01-13 | Kain; Meira | Three-dimensional image viewing apparatus |
| DK0862863T4 (da) * | 1997-01-09 | 2008-12-01 | Nestle Sa | Kornprodukt indeholdende probiotika |
| US7923216B2 (en) * | 1997-08-14 | 2011-04-12 | Institut Pasteur | In vivo modulation of neuronal transport |
| US7923015B2 (en) * | 1997-08-14 | 2011-04-12 | Institut Pasteur | Methods for direct visualization of active synapses |
| US6730499B1 (en) * | 1998-07-03 | 2004-05-04 | Research Corporation Technologies, Inc. | Promoter for the Pichia pastoris formaldehyde dehydrogenase gene FLD1 |
| US6080401A (en) * | 1998-11-19 | 2000-06-27 | Reddy; Malireddy S. | Herbal and pharmaceutical drugs enhanced with probiotics |
| US6090417A (en) * | 1999-03-24 | 2000-07-18 | Kraft Foods, Inc. | Nutritional fortification of natural cheese and method of making |
| US7186560B2 (en) * | 1999-09-21 | 2007-03-06 | Rutgers, The State University Of New Jersey | High level expression of immunogenic proteins in the plastids of higher plants |
| GB0009470D0 (en) * | 2000-04-17 | 2000-06-07 | Univ Southampton | Materials and methods relating to immune responses to fusion proteins |
| EP1292686A1 (en) * | 2000-06-07 | 2003-03-19 | Smittskyddsinstitutet | Gene expression cassette and its use |
| US6881558B1 (en) * | 2000-06-26 | 2005-04-19 | The Trustees Of The University Of Pennsylvania | Expression system for cloning toxic genes |
| US20030165538A1 (en) * | 2000-06-26 | 2003-09-04 | Maxygen Incorporated | Methods and compositions for developing spore display systems for medicinal and industrial applications |
| US20020150594A1 (en) * | 2000-06-26 | 2002-10-17 | Maxygen, Inc. | Methods and compositions for developing spore display systems for medicinal and industrial applications |
| KR20020045400A (ko) * | 2000-12-08 | 2002-06-19 | 반재구 | 포자 표면발현 방법 |
| GB0130789D0 (en) * | 2001-12-21 | 2002-02-06 | King S College London | Application of spores |
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2002
- 2002-03-07 GB GBGB0205376.7A patent/GB0205376D0/en not_active Ceased
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2003
- 2003-03-07 AU AU2003214391A patent/AU2003214391A1/en not_active Abandoned
- 2003-03-07 WO PCT/GB2003/000966 patent/WO2003074681A1/en not_active Ceased
- 2003-03-07 EP EP03709962A patent/EP1495110A1/en not_active Withdrawn
- 2003-03-07 RU RU2004129739/13A patent/RU2004129739A/ru not_active Application Discontinuation
- 2003-03-07 JP JP2003573134A patent/JP2005519123A/ja not_active Withdrawn
- 2003-03-07 CN CNA038054248A patent/CN1639322A/zh active Pending
- 2003-03-07 US US10/506,749 patent/US20050287168A1/en not_active Abandoned
- 2003-03-07 KR KR10-2004-7013611A patent/KR20040099293A/ko not_active Withdrawn
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008231063A (ja) * | 2007-03-22 | 2008-10-02 | Takano Foods Kk | 納豆菌ワクチン |
| JPWO2011111783A1 (ja) * | 2010-03-12 | 2013-06-27 | カルピス株式会社 | 大腸におけるビフィズス菌の増加及び減少抑制剤 |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1639322A (zh) | 2005-07-13 |
| AU2003214391A1 (en) | 2003-09-16 |
| RU2004129739A (ru) | 2005-09-20 |
| KR20040099293A (ko) | 2004-11-26 |
| WO2003074681A1 (en) | 2003-09-12 |
| EP1495110A1 (en) | 2005-01-12 |
| GB0205376D0 (en) | 2002-04-24 |
| US20050287168A1 (en) | 2005-12-29 |
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