JP2005507666A5 - - Google Patents
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- Publication number
- JP2005507666A5 JP2005507666A5 JP2003539604A JP2003539604A JP2005507666A5 JP 2005507666 A5 JP2005507666 A5 JP 2005507666A5 JP 2003539604 A JP2003539604 A JP 2003539604A JP 2003539604 A JP2003539604 A JP 2003539604A JP 2005507666 A5 JP2005507666 A5 JP 2005507666A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- pain
- seq
- polypeptide
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 102000039446 nucleic acids Human genes 0.000 claims 16
- 108020004707 nucleic acids Proteins 0.000 claims 16
- 150000007523 nucleic acids Chemical class 0.000 claims 16
- 108090000765 processed proteins & peptides Proteins 0.000 claims 15
- 150000001875 compounds Chemical class 0.000 claims 14
- 229920001184 polypeptide Polymers 0.000 claims 12
- 102000004196 processed proteins & peptides Human genes 0.000 claims 12
- 239000000203 mixture Substances 0.000 claims 11
- 125000003275 alpha amino acid group Chemical group 0.000 claims 8
- 239000002773 nucleotide Substances 0.000 claims 8
- 125000003729 nucleotide group Chemical group 0.000 claims 8
- 208000027520 Somatoform disease Diseases 0.000 claims 6
- 208000027753 pain disease Diseases 0.000 claims 6
- 210000004027 cell Anatomy 0.000 claims 5
- 230000000694 effects Effects 0.000 claims 5
- 230000008050 pain signaling Effects 0.000 claims 5
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 4
- 230000000692 anti-sense effect Effects 0.000 claims 3
- 230000007246 mechanism Effects 0.000 claims 3
- 238000000034 method Methods 0.000 claims 3
- 208000002193 Pain Diseases 0.000 claims 2
- 230000002159 abnormal effect Effects 0.000 claims 2
- 206010058019 Cancer Pain Diseases 0.000 claims 1
- 208000000094 Chronic Pain Diseases 0.000 claims 1
- 208000001640 Fibromyalgia Diseases 0.000 claims 1
- 206010019233 Headaches Diseases 0.000 claims 1
- 206010065390 Inflammatory pain Diseases 0.000 claims 1
- 208000019695 Migraine disease Diseases 0.000 claims 1
- 208000001294 Nociceptive Pain Diseases 0.000 claims 1
- 210000004958 brain cell Anatomy 0.000 claims 1
- 238000009472 formulation Methods 0.000 claims 1
- 231100000869 headache Toxicity 0.000 claims 1
- 206010027599 migraine Diseases 0.000 claims 1
- 208000004296 neuralgia Diseases 0.000 claims 1
- 210000002569 neuron Anatomy 0.000 claims 1
- 208000021722 neuropathic pain Diseases 0.000 claims 1
- 210000000278 spinal cord Anatomy 0.000 claims 1
- 210000003594 spinal ganglia Anatomy 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33500901P | 2001-10-31 | 2001-10-31 | |
| PCT/US2002/034575 WO2003037258A2 (en) | 2001-10-31 | 2002-10-29 | Methods and compositions for the treatment and diagnosis of pain disorders using 2047 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005507666A JP2005507666A (ja) | 2005-03-24 |
| JP2005507666A5 true JP2005507666A5 (https=) | 2006-01-05 |
Family
ID=23309847
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003539604A Pending JP2005507666A (ja) | 2001-10-31 | 2002-10-29 | ２０４７を用いる、疼痛性障害を治療および診断するための方法および組成物 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20030091572A1 (https=) |
| EP (1) | EP1448152A4 (https=) |
| JP (1) | JP2005507666A (https=) |
| AU (1) | AU2002363229A1 (https=) |
| WO (1) | WO2003037258A2 (https=) |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5464820A (en) * | 1993-06-22 | 1995-11-07 | The University Hospital | Specific inhibitors of tissue kallikrein |
| WO1996019233A2 (en) * | 1994-12-12 | 1996-06-27 | Omeros Medical Systems, Inc. | Irrigation solution and method for inhibition of pain, inflammation and spasm |
| AU4480797A (en) * | 1996-09-13 | 1998-04-02 | Dana-Farber Cancer Institute | Protease m, a novel serine protease |
| US7157084B2 (en) * | 1997-08-21 | 2007-01-02 | The Board Of Trustees Of The University Of Arkansas System | Extracellular serine protease |
-
2002
- 2002-10-29 EP EP02802477A patent/EP1448152A4/en not_active Withdrawn
- 2002-10-29 JP JP2003539604A patent/JP2005507666A/ja active Pending
- 2002-10-29 US US10/282,907 patent/US20030091572A1/en not_active Abandoned
- 2002-10-29 AU AU2002363229A patent/AU2002363229A1/en not_active Abandoned
- 2002-10-29 WO PCT/US2002/034575 patent/WO2003037258A2/en not_active Ceased
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