JP2005341886A - Health food and method for eating and drinking the same - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a health food having a relieving action on an allergic disease in an early period and to provide a method for eating and drinking the health food. <P>SOLUTION: The health food contains powder bodies of Rhinacanthus Nasutus(L)Kurz (Hakkaku-Reishi) and Antler-shaped Fruiting Body of Ganoderma lucidum (Rokkaku-Reishi) or separately has the power bodies. Since the relieving action on allergic disease, especially on hay fever, is synergistically demonstrated if eating and drinking the health food at least once a day, compared to the case of eating and drinking separately each Hakkaku-Reishi and Rokkaku-Reishi, hay fever can be relieved in an early period. <P>COPYRIGHT: (C)2006,JPO&NCIPI

Description

  The present invention relates to a health food having an excellent effect on allergic disease alleviation and a method for eating and drinking the same.

  There have been many health foods using natural products. For example, Hakutsuru Ganoderma is known to have anti-inflammatory action and antibacterial action against skin fungi, and is used as a health food. Moreover, it is also disclosed that the water and / or organic solvent extract of white crane reishi has an antiallergic action against type I allergy represented by hay fever (see Patent Document 1). However, the anti-allergic action of Hakutsuru Ganoderma is not always sufficient, and it has not been put to practical use as an anti-allergic application.

Further, a health food in which dried white crane reishi is mixed with roasted ganoderma or dokudami is also disclosed (see Patent Document 2). However, such a health food is a mixture of the above ingredients in Hakutsuru Reishi in order to give a sufficient flavor when drinking, and so far among health foods in which Hakutsuru Reishi and other natural products are mixed, Nothing that promotes alleviation of allergic diseases has been disclosed (see Patent Document 2).
JP 2001-10964 A Japanese Patent Laid-Open No. 9-168377

  This invention is made | formed in view of the said problem, The objective is to provide the health food which has the effect | action which alleviates an allergic disease at an early stage, and its eating and drinking method.

  As a result of intensive studies to solve the above problems, the present inventor has found that a synergistic effect is exhibited with respect to alleviation of allergic diseases by eating and drinking white crane reishi powder and kakuno reishi powder, The present invention has been completed.

  That is, the invention of claim 1 provides a health food characterized in that it contains white crane reishi powder and kakuno reishi powder, or these are provided separately. According to a second aspect of the present invention, there is provided the health food according to the first aspect, wherein the white crane reishi powder has a particle size that passes through a sieve of 100 mesh or more, and the kakukaku reishi powder is a sieve of 150 mesh or more. It is characterized by having a particle size that passes through.

  According to a third aspect of the present invention, in the health food according to the second aspect, the white crane reishi powder and the kakukaku reishi powder are blended in a weight ratio of 1: 0.3 to 1. It is characterized by. According to a fourth aspect of the present invention, in the health food of the second aspect, the white crane reishi powder and the kakukaku reishi powder are blended in a weight ratio of 1: 0.3-1 to eat and drink. Alternatively, the white crane reishi powder and the kakukaku reishi powder are eaten and eaten at a ratio of 1: 0.3 to 1 in a weight ratio in another time zone. The invention according to claim 5 is characterized in that the health food according to any one of claims 1 to 4 is for allergy disease alleviation. The invention according to claim 6 is the health food according to claim 5, wherein the allergic disease is hay fever.

  The invention of claim 7 is the method for eating and drinking the health food according to any one of claims 1 to 6, wherein the white crane reishi powder and the kakukaku reishi powder are consumed at least once a day. It is characterized by doing. According to an eighth aspect of the present invention, in the method for eating and drinking a health food according to the seventh aspect of the invention, the white crane ganoderma powder and the kakukaku ganoderma powder are simultaneously consumed.

  According to the health food of the present invention, the alleviation of symptoms for allergic diseases, in particular hay fever, is exhibited synergistically compared with the case where white crane reishi and kakuno reishi are eaten and consumed individually. Can be alleviated early.

  The health food of the present invention is characterized in that it contains white crane reishi powder and kakuno reishi powder, or is provided with these separately. And by eating and drinking the health food of this invention, the outstanding effect that allergic disease, especially hay fever can be relieved at an early stage is exhibited.

  Rhinacanthus Nastus (L) Kurz is a perennial that belongs to the genus Solanum genus, and a commercially available product can be used in the present invention. The use site of white crane reishi is not particularly limited, and leaves, flowers, stems and roots can be used alone or in combination. In these, the part of a leaf is especially preferable from a viewpoint of the early relaxation effect with respect to hay fever when eating and drinking the health food obtained, and suppression of manufacturing cost.

  In the present invention, the white crane reishi is used, for example, in the form of powder by sterilizing and then pulverizing a commercially available product. Here, the purpose of sterilizing the white crane ganoderma is to ensure the safety of the resulting health food. The particle size of Hakutsuru Ganoderma powder is not particularly limited as long as it is excellent in the absorbability when eating and drinking the obtained health food, but the upper limit value usually passes through a sieve of 50 mesh or more. Used, preferably those passed through a sieve of 100 mesh or more. In addition, the lower limit of the particle size of the powder is not particularly limited, but from the viewpoint of preventing variation in the early mitigating action against hay fever when eating and drinking the obtained health food, one that does not normally pass through a sieve of 200 mesh or less, preferably That does not pass through a sieve of 150 mesh or less is used.

  Kazuno Ganoderma is a kind of Ganoderma belonging to the moss and has a shape like a deer antler. In addition, Kazuno Ganoderma is characterized in that it has a higher β-D-glucan content than ordinary ganoderma, and a commercially available product can be used in the present invention. In the present invention, Kazuno Ganoderma is used, for example, in the form of powder after sterilizing and then pulverizing a commercially available product. Here, the purpose of sterilizing Kazuno Ganoderma is to ensure the safety of the resulting health food. The particle size of Kazuno Ganoderma powder is not particularly limited as long as it is a size excellent in the body absorbability when eating and drinking the obtained health food, but the upper limit value usually passes through a sieve of 150 mesh or more And those that have passed through a sieve of 250 mesh or more, more preferably those that have passed through a sieve of 300 mesh or more. By using powder that has passed through a sieve of 150 mesh or more, hay fever can be alleviated early when the resulting health food is consumed.

  Although the lower limit of the particle size of Kakuno Ganoderma is not particularly limited, it usually does not pass through a sieve of 350 mesh or less from the viewpoint of preventing variation in the early mitigation action against hay fever when eating and drinking the resulting health food. Things are used.

  The health food of the present invention contains the white crane reishi powder and the kakukaku reishi powder as essential components (hereinafter, the health food containing the two essential components is referred to as a blended product). The blending ratio of Kazuno Ganoderma powder is usually 30 parts by weight or more, preferably 50 parts by weight or more, and more preferably 100 parts by weight or more with respect to 100 parts by weight of White Crane Reishi powder. In addition, the upper limit of the kakukaku reishi powder is not particularly limited, but it is usually preferably the same or less than the white crane reishi powder. That is, the white crane ganoderma powder and deer antacula powder in the blended product are usually 1: 0.3 to 1, preferably 1: 0.5 to 1, more preferably 1: 0. It is preferable to mix | blend in the ratio of 7-1. By eating and drinking the health food containing the two essential ingredients in such a ratio, the symptom-relieving action is synergistically exhibited for hay fever as compared with the case where each of them is eaten and consumed alone. Can be mitigated at an early stage, and it is not necessary to increase the blending ratio of Kazuno Ganoderma more than necessary, so that the manufacturing cost of health food can be suppressed.

  In the health food of the present invention, additives that are usually used in food can be further blended within a range that does not impair the effects of the present invention. Examples of such additives include vitamins, sweeteners, seasonings, acidulants, preservatives, fragrances, colorants and the like, and these can be used alone or in combination of two or more.

  The dosage form of the health food is not particularly limited as long as it contains the essential 2 components as a powder. For example, in addition to the powder prepared by mixing the essential 2 components and the additive as necessary, a known method may be used. It can be supplied as capsules, dry syrups and the like.

  Further, unlike the blended product described above, the health food of the present invention does not contain the white crane ganoderma powder and the kakukaku ganoderma powder, but is provided in a form provided separately. (Hereafter, a health food provided with the two essential ingredients separately is referred to as a set product). Additives commonly used in foods can be further blended with the white crane reishi powder and kakuno reishi powder constituting the set product as long as the effects of the present invention are not impaired. Examples of such additives include vitamins, sweeteners, seasonings, acidulants, preservatives, fragrances, colorants and the like, and these can be used alone or in combination of two or more. In addition, the dosage form of the set product is not particularly limited, and for example, in addition to the powder containing the two essential components and the additive as necessary, it is supplied as a capsule or a dry syrup using a known method. be able to.

  The method for eating and drinking the health food of the present invention is not particularly limited, but it is preferable to eat and drink at least once a day in order to alleviate hay fever as early as possible. Here, “to eat and drink at least once a day” includes eating and drinking the two essential components at different times, in addition to eating and drinking the two essential components at the same time. Examples of the method for simultaneously eating and drinking the two essential components include a method for eating and drinking the blended product as it is, and a method for eating and drinking the two essential components constituting the set product without or mixing them. On the other hand, when eating and drinking the two components in different time zones, the set product may be used.

  In the case of eating and drinking the two components using a set product, the ratio of the kakukaku reishi powder is usually 30 parts by weight or more, preferably 50 parts by weight, with respect to 100 parts by weight of the white crane reishi powder. Above, more preferably 100 parts by weight or more. In addition, the upper limit for eating and drinking Kakuno Ganoderma powder is not particularly limited, but it is usually preferably the same or less than the white crane Ganoderma powder. That is, the white crane ganoderma powder and deer ganoderma powder are usually in a weight ratio of 1: 0.3 to 1, preferably 1: 0.5 to 1, and more preferably 1: 0.7 to 1. It is preferable to eat and drink at a ratio of Eating and drinking the essential two components at such a ratio synergistically exerts a symptom-relieving effect on hay fever as compared to the case where each of them is consumed alone, thereby alleviating hay fever early. In addition, it is possible to reduce the cost of using health foods because it is not necessary to increase the amount of food consumed at Kazuno Reishi more than necessary.

  When eating and drinking the health food of the present invention, it is preferable to eat and drink with water or the like, for example, in order to make it easier to eat and drink the health food. In addition, when eating and drinking set products, when eating and drinking the two essential ingredients at different times, in addition to eating and drinking white crane reishi powder with water etc., decocting white crane reishi powder Can be drunk. Moreover, although there are individual differences in the amount of food consumed per day for health foods, it is generally about 2 g of white crane ganoderma and about 0.7 to 2 g of kakuno ganoderma. When decocting white crane reishi powder, for example, 2 g of white crane reishi powder can be decocted to make 500 ml of decoction, and this decoction can be divided into two morning and evening drinks. it can.

  As described above, if the health food of the present invention containing the essential two component powders or having them separately is eaten or consumed, various symptoms of hay fever after two or three days have passed. Is reduced. In the present invention, hay fever effective for symptom reduction is not particularly limited, and examples thereof include cedar pollinosis, hinoki hay fever, gramineous hay fever, ragweed hay fever, and hay fever with other pollen as an allergen. Moreover, the said effect is exhibited regardless of gender and pollen medical history.

  In addition, among the two essential components, by setting the particle size of deer antrum mainly within the above-mentioned preferred range, after eating and drinking health foods, after 2 to 3 days, various types of hay fever are observed. Symptoms are almost halved. Furthermore, by setting the weight ratio (dietary ratio) of the essential two components in the previous period within a suitable range and eating and drinking a sufficient amount of health food, most of the test is conducted before 1 week has passed since the health food was consumed. An excellent effect of stopping various symptoms of hay fever is exhibited. In addition, the health food of the present invention is expected to have an excellent antiallergic action against type I allergies such as bronchial asthma, allergic rhinitis, urticaria, atopic dermatitis, drug allergy, etc. .

  EXAMPLES Hereinafter, although an Example demonstrates this invention further in detail, this invention is not limited at all by these Examples.

(Production example of white crane reishi powder)
Hakutsuru Reishiba leaves (sales of Daikyo Bussan Co., Ltd.) were sterilized in an autoclave at 100 to 120 ° C. for 2 hours, then pulverized with a pulverizer, and the resulting pulverized product was passed through a 150 mesh sieve . Subsequently, the powder that passed through the sieve was passed through a 200 mesh sieve, and the powder that did not pass through the sieve was subjected to a food and drink test described below. In addition, the white crane reishi used as a raw material is from Taiwan, and is a tea leaf obtained by semi-fermenting a white crane reishi leaf obtained by a completely organic farming method in a soil having a pH of 3.7 to 5.5.

(Manufacturing example 1 of Kakuno Reishi powder)
Kazuno Ganoderma (Daikyo Bussan Co., Ltd.) was sterilized in an autoclave at 100 to 120 ° C. for 2 hours, then pulverized with a pulverizer, and the resulting pulverized product was passed through a 150 mesh sieve. Subsequently, the powder that passed through the sieve was passed through a 200-mesh sieve, and the powder that did not pass through the sieve was subjected to the eating and drinking test described later as a “150-mesh pass product”. In addition, Kazuno Ganoderma used as a raw material was obtained by a completely organic farming method in Wuyi Mountain, Fujian Province, China. Also in the manufacturing example 2 of the kakukaku reishi described below, the kakukaku reishi used as a raw material is the same as that of this manufacturing example 1.

(Manufacturing example 2 of Kakuno Reishi powder)
The kakukaku reishi was sterilized in an autoclave at 100 to 120 ° C. for 2 hours, then pulverized by a pulverizer, and the obtained pulverized product was passed through a 300 mesh sieve. Subsequently, the powder that passed through the sieve was passed through a 350-mesh sieve, and the powder that did not pass through the sieve was subjected to a food and drink test described later as a “300-mesh pass product”.

(Health food eating and drinking test by monitor)
[monitor]
Twelve persons (A to L) who had a history of taking hay fever medicines and supplements and had a history of going to hospital before the eating and drinking test were used as monitors. The sex of each monitor was 4 males, 8 females, the age group was 24-61 years old, and the history of hay fever was 3-15 years. In this study, the subjects were Japanese cedar pollinosis, Japanese cypress pollinosis, Gramineae pollinosis or ragweed pollinosis.

[Summary of the test and its criteria]
The health food described below was eaten daily by the monitor for 6 days under the following conditions, and asked how much the symptoms of hay fever on the day were improved before going to bed at night. Judgment criteria are as follows.
A: The symptoms of hay fever (itching of eyes and / or rhinitis) stopped.
○: Symptoms of hay fever (itching of eyes and / or rhinitis) were halved compared to before eating and drinking.
Δ: Symptoms of hay fever (itching of eyes and / or rhinitis) were slightly lighter than before eating and drinking.
X: No change compared to before eating and drinking.
During the eating and drinking period, no hay fever drug or supplement was given to the monitor, and no health food was consumed when the patient was in poor health such as fever.

[Test 1]
In about 800 mL of water, 2 g of the white crane reishi powder obtained above was placed and boiled to 500 mL with boiling water, then the decoction obtained was cooled. And this cold decoction was drunk every day in two mornings and evenings by each monitor. The study period is from April 1, 2000 to April 6, 2000 for the monitoring of Japanese cedar pollinosis or cypress pollinosis, and from May 20, 2000 to May of the same year for the monitoring of gramineous hay fever or ragweed pollinosis. The 25th. The results are shown in Table 1.

[Test 2]
2 g of the white crane reishi powder obtained above was eaten daily at 9 pm with water on each monitor. The study period was from April 20, 2000 to April 25, 2000 for the monitor of Japanese cedar pollinosis or Japanese cypress pollinosis, and from June 10, 2000 to June of the same year for the monitor of gramineous hay fever or ragweed pollinosis. 15 days. The results are shown in Table 2.

[Test 3]
Each monitor was allowed to eat and drink 1.5 g of the Kazuno Ganoderma powder (150 mesh pass product) with water at 9:00 pm every day. The study period was from April 1, 2001 to April 6, 2001 for the monitor of Japanese cedar pollinosis or cypress pollinosis, and from May 20, 2001 to May of the same year for the monitor of gramineous hay fever or ragweed pollinosis. The 25th. The results are shown in Table 3.

[Test 4]
Each monitor was allowed to eat and drink 1.5 g of the Kazuno Ganoderma powder (300 mesh pass product) with water at 9:00 pm every day. The study period was from April 20, 2001 to April 25, 2001 for the monitor of Japanese cedar pollinosis or cypress pollinosis, and from June 10, 2001 to June of the same year for the monitor of gramineous hay fever or ragweed pollinosis. It was 15th. The results are shown in Table 4.

[Test 5]
A decoction made under the same conditions as in Test 1 is taken daily by each monitor in two mornings and evenings, and 1.5 g of the Kakukaku Reishi powder (150 mesh pass product) is mixed with water. At 9pm every day. The study period was from April 1, 2002 to April 6, 2002 for monitors of Japanese cedar pollinosis or cypress pollinosis, and from May 20, 2002 to May of the same year for monitors of gramineous hay fever or ragweed pollinosis. The 25th. The results are shown in Table 5.

[Test 6]
2 g of the white crane ganoderma powder obtained above and 1.5 g of the kakukaku ganoderma powder (150 mesh pass product) were eaten and consumed daily at 9 pm with water in each monitor. The test period was from April 20, 2002 to April 25, 2002 for monitoring of Japanese cedar pollinosis or cypress pollinosis, and from June 10, 2002 to June of the same year for monitoring gramineous hay fever or ragweed pollinosis. 15 days. The results are shown in Table 6.

[Test 7]
A decoction made under the same conditions as in Test 1 was taken daily by each monitor in two mornings and evenings, and 1.5 g of the Kakukaku Reishi powder (300 mesh pass product) was mixed with water. At 9pm every day. The study period is from April 1, 2003 to April 6, 2003 for the monitor of Japanese cedar pollinosis or cypress pollinosis, and from May 20, 2003 to May of the same year for the monitor of gramineous hay fever or ragweed pollinosis. The 25th. The results are shown in Table 7.

[Test 8]
A plurality of capsules were prepared by encapsulating a health food in which 0.2 g of the white crane ganoderma powder obtained above and 0.075 g of the kakukaku ganoderma powder (300 mesh pass product) were encapsulated in gelatin capsules. Ten capsules were eaten daily at 9pm with water on each monitor. The study period was from April 10, 2003 to April 15, 2003 for the monitor of Japanese cedar pollinosis or cypress pollinosis, and from June 1, 2003 to June of the same year for the monitor of gramineous hay fever or ragweed pollinosis. 6 days. The results are shown in Table 8.

[Test 9]
A plurality of capsules are prepared by encapsulating a health food in which 0.2 g of the white crane reishi powder obtained above and 0.1 g of the kakukaku reishi powder (300 mesh pass product) are encapsulated in gelatin capsules. Ten capsules were eaten daily at 9pm with water on each monitor. The study period was from April 20, 2003 to April 25, 2003 for the monitoring of Japanese cedar pollinosis or cypress pollinosis, and from June 10, 2003 to June of the same year for the monitoring of gramineous hay fever or ragweed pollinosis. 15 days. The results are shown in Table 9.

[Test 10]
A plurality of capsules containing health foods mixed with 0.2 g of white crane reishi powder obtained above and 0.15 g of kakukaku reishi powder (300 mesh pass product) in gelatin capsules were prepared. Ten capsules were eaten daily at 9pm with water on each monitor. The study period was from April 30, 2003 to May 5, 2003 for the monitoring of Japanese cedar pollinosis or cypress pollinosis, and from June 20, 2003 to June of the same year for the monitoring of gramineous hay fever or ragweed pollinosis. The 25th. The results are shown in Table 10.

[Test results]
Tables 1 to 4 correspond to Tests 1 to 4, respectively, and show the alleviation effect of hay fever when drinking or eating or drinking white crane reishi powder or kakuno reishi powder. . First, it can be seen from the results of Tables 1 and 2 that there is almost no alleviating effect of hay fever even if white crane reishi powder is drunk or eaten or consumed alone. Further, from the results of Tables 3 and 4, even when the kakukaku reishi powder is consumed alone, the effect of alleviating hay fever is the same as when the white crane reishi powder is drunk or eaten alone. There is almost no. However, the effect of reducing the symptom of hay fever was slightly observed by reducing the particle size of Kakuno Reishi to 300-350 mesh (see Table 4).

  Tables 5-10 correspond to Tests 5-10, respectively, and showed the alleviation effect of hay fever when eating and drinking white crane reishi powder and kakuno reishi powder at least once a day. Is. Comparing Table 5, Table 1 and Table 3, in Table 1, 1 out of 12 monitors is slightly less symptom of hay fever than before eating, and in Table 3 all 12 out of 12 monitors are before eating and drinking. There was no change in the symptoms of hay fever. On the other hand, in Table 5, 11 out of 12 monitors showed a slightly reduced hay fever symptom compared to before eating and drinking. From the above, when eating and drinking the health food of Test 5, the alleviating effect of symptom on hay fever is synergistically exhibited compared with the case of eating and drinking Hakuzuru Reishi and Kazuno Ganoderma which constitute this health food. It was found that this can alleviate hay fever early.

  This tendency is similarly observed when Table 6, Table 2, and Table 3 are compared, when Table 7, Table 1, and Table 4 are compared, and when Table 10, Table 2, and Table 4 are compared. Also, comparing Table 5, Table 6, Table 7 and Table 8, in order to alleviate hay fever early, it is better to eat and drink white crane reishi powder with water rather than drinking it as a decoction. Preferably (see Table 5 and Table 6), it was found that the grain size of Kakuno Ganoderma was preferably 300-350 mesh rather than 150-200 mesh (Tables 5 and 7, Tables 6 and 10 respectively). reference).

Tables 8 to 10 correspond to Tests 8 to 10, respectively, and examine the blending ratio of the two components for health foods containing white crane reishi powder and kakukaku reishi powder, respectively. .
As a result, among the two ingredients, the early alleviation effect of hay fever becomes more remarkable as the blending ratio of Kakuno Ganoderma increases, and in Test 10, 9 out of 12 monitors stop symptom of hay fever. Indicated. Nine monitors whose hay fever symptoms stopped showed no hay fever symptoms until May of the following year (2004).

[Test 11]
Test D and F and 10 new monitors (M to V) whose hay fever symptoms were halved in Test 10 compared to before eating and drinking were tested in the same condition as Test 10 in the year following Test 10. It was. The test period was April 20, 2004 to April 25, 2004. The results are shown in Table 11.

  From Table 11, the symptoms of hay fever completely ceased after 4 days have passed since both monitors D and F, whose symptoms worsened to the same extent as in the previous year before the start of the test. In addition, it was found that symptom of hay fever completely stopped in 6 out of 10 new monitors. As described above, the reproducibility of the alleviating action against hay fever of the health food used in Test 10 was confirmed from the results of Test 11.

Claims (8)

  A health food characterized by containing Hakutsuru Reishi powder and Kazuno Reishi powder, or comprising these separately.   The white crane Reishi powder has a particle size that passes through a sieve of 100 mesh or more, and the powder of Kazuno Reishi has a particle size that passes through a sieve of 150 mesh or more. Healthy food.   3. The health food according to claim 2, wherein the white crane reishi powder and the kakukaku reishi powder are blended at a weight ratio of 1: 0.3-1.   Eating and drinking Hakutsukaku Reishi powder and Kakukaku Reishi powder in a weight ratio of 1: 0.3 to 1, or Hakutsukaku Reishi powder and Kakukaku Reishi powder The health food according to claim 2, wherein the food is eaten or eaten at a time ratio of 1: 0.3 to 1 in another time zone.   The health food according to any one of claims 1 to 4, which is used for alleviating allergic diseases.   The health food according to claim 5, wherein the allergic disease is hay fever.   The method for eating and drinking a health food according to any one of claims 1 to 6, wherein the white crane reishi powder and the kakukaku reishi powder are eaten and consumed at least once a day.   8. The method for eating and drinking a health food according to claim 7, wherein the white crane reishi powder and the kakukaku reishi powder are simultaneously consumed.