Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
水溶液中で１，４−シクロヘキサンジカルボン酸ジアルキルを酸性触媒存在下に加水分解反応させて１，４−シクロヘキサンジカルボン酸を得る方法であって、水及び加水分解反応中に副生するアルコールを反応系外に連続的に蒸発させながら、水を反応系に連続的又は間欠的に添加して加水分解反応させることを特徴とする１，４−シクロヘキサンジカルボン酸の製造方法。
A method for obtaining 1,4-cyclohexanedicarboxylic acid by hydrolyzing a dialkyl 1,4-cyclohexanedicarboxylate in an aqueous solution in the presence of an acidic catalyst, comprising reacting water and alcohol by-produced during the hydrolysis reaction. A process for producing 1,4-cyclohexanedicarboxylic acid, wherein water is continuously or intermittently added to the reaction system to cause a hydrolysis reaction while continuously evaporating to the outside.
液空間速度が、反応液容量を基準として０.２〜０.０５／ｈになるように水を添加して反応させる請求項１に記載の１，４−シクロヘキサンジカルボン酸の製造方法。
The method for producing 1,4-cyclohexanedicarboxylic acid according to claim 1, wherein water is added and reacted so that the liquid space velocity is 0.2 to 0.05 / h based on the reaction liquid volume.
１，４−シクロヘキサンジカルボン酸ジアルキルが、テレフタル酸ジアルキルの核水素化反応により製造されたものである請求項１又は２に記載の１，４−シクロヘキサンジカルボン酸の製造方法。
The method for producing 1,4-cyclohexanedicarboxylic acid according to claim 1 or 2, wherein the dialkyl 1,4-cyclohexanedicarboxylate is produced by a nuclear hydrogenation reaction of dialkyl terephthalate.
１，４−シクロヘキサンジカルボン酸ジアルキルが、１，４−シクロヘキサンジカルボン酸ジメチルである請求項１〜３のいずれかに記載の１，４−シクロヘキサンジカルボン酸の製造方法。
The method for producing 1,4-cyclohexanedicarboxylic acid according to any one of claims 1 to 3, wherein the dialkyl 1,4-cyclohexanedicarboxylate is dimethyl 1,4-cyclohexanedicarboxylate.
加水分解反応後の１，４−シクロヘキサンジカルボン酸中の有機不純物の含有量が０．１重量％以下であることを特徴とする請求項１〜４のいずれか１項に記載の１，４ −シクロヘキサンジカルボン酸の製造方法。
The content of organic impurities in 1,4-cyclohexanedicarboxylic acid after the hydrolysis reaction is 0.1% by weight or less. A method for producing cyclohexanedicarboxylic acid.
A flexible approach to construct three contiguous chiral centers of sphingolipids, and asymmetric synthesis of d-ribo-phytosphingosine and its derivatives