JP2005298373A5 - - Google Patents

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Publication number
JP2005298373A5
JP2005298373A5 JP2004114046A JP2004114046A JP2005298373A5 JP 2005298373 A5 JP2005298373 A5 JP 2005298373A5 JP 2004114046 A JP2004114046 A JP 2004114046A JP 2004114046 A JP2004114046 A JP 2004114046A JP 2005298373 A5 JP2005298373 A5 JP 2005298373A5
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JP
Japan
Prior art keywords
sugar
coated
tablet
coated tablet
amino acid
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Pending
Application number
JP2004114046A
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Japanese (ja)
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JP2005298373A (en
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Priority to JP2004114046A priority Critical patent/JP2005298373A/en
Priority claimed from JP2004114046A external-priority patent/JP2005298373A/en
Publication of JP2005298373A publication Critical patent/JP2005298373A/en
Publication of JP2005298373A5 publication Critical patent/JP2005298373A5/ja
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Claims (17)

プロリン、ヒスチジン、システイン、オルニチン及びアルギニンの群より選ばれる吸水性アミノ酸及びエタノール可溶性かつ水難溶性被覆剤を含有する錠剤に、糖衣が施されていることを特徴とする糖衣錠剤。 A sugar-coated tablet characterized in that a sugar coating is applied to a tablet containing a water-absorbing amino acid selected from the group of proline, histidine, cysteine, ornithine and arginine and an ethanol-soluble and poorly water-soluble coating agent. プロリン、ヒスチジン、システイン、オルニチン及びアルギニンの群より選ばれる吸水性アミノ酸を含有するアミノ酸顆粒を含有し、該顆粒がエタノール可溶性かつ水難溶性被覆剤で被覆されている錠剤に、糖衣が施された糖衣錠剤。 Sugar -coated tablets containing amino acid granules containing a water-absorbing amino acid selected from the group of proline, histidine, cysteine, ornithine and arginine, and the granules coated with an ethanol-soluble and poorly water-soluble coating agent Agent. エタノール可溶性かつ水難溶性被覆剤がシェラック又はゼインであることを特徴とする請求項１に記載の糖衣錠剤。 The sugar-coated tablet according to claim 1, wherein the ethanol-soluble and poorly water-soluble coating agent is shellac or zein. プロリン、ヒスチジン、システイン、オルニチン及びアルギニンの群より選ばれる吸水性アミノ酸を含有するアミノ酸顆粒を含有し、該顆粒がシェラック又はゼインで被覆されている錠剤に、糖衣が施されていることを特徴とする糖衣錠剤。 A tablet comprising an amino acid granule containing a water-absorbing amino acid selected from the group of proline, histidine, cysteine, ornithine and arginine, wherein the granule is coated with shellac or zein, and sugar-coated. sugar-coated tablets to be. 吸水性アミノ酸が、錠剤中１０〜７０質量％含まれることを特徴とする請求項１〜４のいずれかに記載の糖衣錠剤。   The sugar-coated tablet according to any one of claims 1 to 4, wherein the water-absorbing amino acid is contained in the tablet in an amount of 10 to 70% by mass. さらに、バリン、ロイシン及びイソロイシンの群より選ばれる分岐鎖アミノ酸を、錠剤中５〜６０質量％含まれることを特徴とする請求項１〜５のいずれかに記載の糖衣錠剤。Furthermore, 5-60 mass% of branched chain amino acids chosen from the group of a valine, a leucine, and an isoleucine are contained in a tablet, The sugar-coated tablet in any one of Claims 1-5 characterized by the above-mentioned. 糖衣錠剤がチュアブル錠である請求項１〜６のいずれかに記載の糖衣錠剤。 The sugar-coated tablet is a chewable tablet, and the sugar-coated tablet according to any one of claims 1 to 6 . 糖衣の内層としてのゼイン又はシェラックを含有する保護皮膜を、錠剤質量に対して１〜５質量％含むことを特徴とする請求項１〜７のいずれかに記載の糖衣錠剤。 The sugar-coated tablet according to any one of claims 1 to 7 , comprising 1 to 5% by mass of a protective film containing zein or shellac as an inner layer of the sugar-coated layer based on the tablet mass . 糖衣が、マルチトール、エリスリトール、ラクチトール、キシリトール及びパラチニットから選択される１種又は２種以上を含有することを特徴とする請求項１〜８のいずれかに記載の糖衣錠剤。   The sugar-coated tablet according to any one of claims 1 to 8, wherein the sugar-coated tablet contains one or more selected from maltitol, erythritol, lactitol, xylitol, and palatinit. 糖衣が、さらにアラビアゴムを含有する糖衣である請求項９に記載の糖衣錠剤。   The sugar-coated tablet according to claim 9, wherein the sugar-coated tablet is a sugar-coated tablet further containing gum arabic. 糖衣の量が錠剤質量に対して３０〜６０質量％であることを特徴とする請求項１〜１０のいずれかに記載の糖衣錠剤。   The sugar-coated tablet according to any one of claims 1 to 10, wherein the amount of sugar-coated is 30 to 60% by mass relative to the mass of the tablet. プロリン、ヒスチジン、システイン、オルニチン及びアルギニンの群より選ばれる吸水性アミノ酸含有アミノ酸顆粒をエタノール可溶性かつ水難溶性被覆剤で被覆し、得られたエタノール可溶性かつ水難溶性被覆剤で被覆されている吸水性アミノ酸含有アミノ酸顆粒と添加剤とを含有する粉粒体を調製し、得られた粉粒体を打錠し、次いで得られた錠剤を糖衣工程に付することを特徴とする糖衣錠剤の製造法。 A water-absorbing amino acid-containing amino acid granule selected from the group of proline, histidine, cysteine, ornithine and arginine is coated with an ethanol-soluble and hardly water-soluble coating agent, and the resulting water-absorbing amino acid is coated with an ethanol-soluble and hardly water-soluble coating agent. A method for producing a sugar-coated tablet, comprising preparing a granular material containing an amino acid granule and an additive, compressing the obtained granular material, and then subjecting the obtained tablet to a sugar coating step. 吸水性アミノ酸を、錠剤中１０〜７０質量％含ませることを特徴とする請求項１２に記載の糖衣錠剤の製造法。  The method for producing a sugar-coated tablet according to claim 12, wherein 10 to 70% by mass of a water-absorbing amino acid is contained in the tablet. さらに、バリン、ロイシン及びイソロイシンの群より選ばれる分岐鎖アミノ酸を、錠剤中５〜６０質量％含ませることを特徴とする請求項１２又は１３に記載の糖衣錠剤の製造法。Furthermore, 5-60 mass% of branched chain amino acids chosen from the group of valine, leucine, and isoleucine are included in a tablet, The manufacturing method of the sugar-coated tablet of Claim 12 or 13 characterized by the above-mentioned. 糖衣錠剤がチュアブル錠である請求項１２〜１４のいずれかに記載の糖衣錠剤の製造法。  The sugar-coated tablet is a chewable tablet, The method for producing a sugar-coated tablet according to any one of claims 12 to 14. 糖衣工程が、糖衣の内層としてのゼイン又はシェラックを含有する皮膜を錠剤に施す工程を含むことを特徴とする請求項１２〜１５のいずれかに記載の糖衣錠剤の製造法。 The method for producing a sugar-coated tablet according to any one of claims 12 to 15 , wherein the sugar- coating step comprises a step of applying a film containing zein or shellac as an inner layer of the sugar coating to the tablet . 糖衣がマルチトール、エリスリトール、ラクチトール、キシリトール及びパラチニットから選択される１種又は２種以上を含むことを特徴とする請求項１２〜１６のいずれかに記載の糖衣錠剤の製造法。
The method for producing a sugar-coated tablet according to any one of claims 12 to 16, wherein the sugar-coating comprises one or more selected from maltitol, erythritol, lactitol, xylitol, and palatinit.
JP2004114046A 2004-04-08 2004-04-08 Sugar-coated tablet containing water absorptive amino acid Pending JP2005298373A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2004114046A JP2005298373A (en) 2004-04-08 2004-04-08 Sugar-coated tablet containing water absorptive amino acid

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2004114046A JP2005298373A (en) 2004-04-08 2004-04-08 Sugar-coated tablet containing water absorptive amino acid

Publications (2)

Publication Number Publication Date
JP2005298373A JP2005298373A (en) 2005-10-27
JP2005298373A5 true JP2005298373A5 (en) 2007-05-17

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Family Applications (1)

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JP2004114046A Pending JP2005298373A (en) 2004-04-08 2004-04-08 Sugar-coated tablet containing water absorptive amino acid

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Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20070077A1 (en) * 2005-06-10 2007-02-07 Takeda Pharmaceutical COMPRESSED WITH SUGAR COATED
RU2436484C2 (en) * 2007-06-07 2011-12-20 КТ энд ДЖИ КОРПОРЕЙШН Cigarette filter containing vegetal material and cigarette
JP2010270111A (en) * 2009-04-21 2010-12-02 Taisho Pharmaceutical Co Ltd Arginine-containing tablet
JP5446716B2 (en) * 2009-10-21 2014-03-19 大正製薬株式会社 Method for producing tablets containing arginine and carnitine
JP5600450B2 (en) * 2010-03-11 2014-10-01 日本メナード化粧品株式会社 Sugar-coating liquid
WO2013161815A1 (en) * 2012-04-23 2013-10-31 味の素株式会社 Tablet containing glutamic acid and arginine at high contents
JP5991472B2 (en) * 2012-08-31 2016-09-14 アサヒグループ食品株式会社 Appearance change suppressing tablet, method for producing the same, and tablet appearance change suppressing method
JP5991473B2 (en) * 2012-08-31 2016-09-14 アサヒグループ食品株式会社 Granules and production method thereof, blocking inhibiting method in granule production, and tablet and production method thereof, and sticking inhibiting method in tablet production
US20140100236A1 (en) 2012-10-09 2014-04-10 Boehringer Ingelheim International Gmbh Use of selectively moisture-adjusted tabletting material in the production of mechanically stable tablets which contain at least one hydrate-forming active substance and/or adjuvant relevant to the mechanical stability of the tablets, particularly arginine-containing tablets

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5077053A (en) * 1990-02-12 1991-12-31 Warner-Lambert Company Zein as a moisture barrier for sugarless edible compositions and method for preparing same
JP2801728B2 (en) * 1990-03-13 1998-09-21 フロイント産業株式会社 Sugar-coated product and method for producing the same
JP2002179559A (en) * 2000-10-06 2002-06-26 Takeda Chem Ind Ltd Thin-layer sugar-coated tablet and method for producing the same
JP4856323B2 (en) * 2001-06-15 2012-01-18 エスエス製薬株式会社 Method for producing stable enteric-coated sugar-coated tablets
JP2003095928A (en) * 2001-09-27 2003-04-03 Kowa Co Sugar coated pharmaceutical preparation
WO2003041698A1 (en) * 2001-11-13 2003-05-22 Kyowa Hakko Kogyo Co., Ltd. Amino acid-containing tablets quickly disintegrating in the oral cavity and process for producing the same
WO2004016262A1 (en) * 2002-08-12 2004-02-26 Kyowa Hakko Kogyo Co., Ltd. Amino acid-containing chewable

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