JP2005187030A - Flexible multi-chamber container - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To prevent a medicine stored in a flexible multi-chamber container from being given to a patient before mixture. <P>SOLUTION: The flexible multi-chamber container 1 includes a container body 2 consisting of an upper chamber 10 and a lower chamber 20 sectioned via a partitioning means 30 capable of communicating when needed, and a discharge port 40 provided on the lower chamber 20. At least part of the surface of the lower chamber 20 is covered with a cover means 50. The cover means 50 is made in a structure separably connected via a connection 70 with a sealing means 60 for sealing a part 41 to be pierced of the discharge port 40. <P>COPYRIGHT: (C)2005,JPO&NCIPI

Description

  The present invention relates to a flexible multi-chamber container. More specifically, the present invention relates to a flexible multi-chamber container in which a covering means for covering a part of a chamber and a sealing means for sealing a discharge port are connected to each other.

  In recent years, drug containers have been widely used in which unstable drugs in a mixed state are separated and stored in a single container and used aseptically before use. As such a drug container, a flexible multi-chamber container is well known in which a container is formed by a flexible film made of plastic or the like, and the inside thereof is partitioned by a weak seal portion capable of communicating by pressing. (For example, refer to Patent Document 1).

  However, since a container such as Patent Document 1 can discharge a medicine without performing weak seal communication, there is a possibility that the medicine before mixing may be administered to a patient if the weak seal communication is forgotten. Especially in hospitals with a large number of beds, pharmacists and the like may perform mixing operations on flexible multi-chamber containers in the dispensing section, so bedside nurses and the like can use sealing means to seal the puncture site of the discharge port. In many cases, only the operation of peeling off (for example, the tamper seal) is performed. Therefore, if the mixing operation is not performed in the dispensing unit, there is a possibility that an unmixed drug is administered to the patient without performing a mixing operation at the clinical site.

  In view of this, a flexible multi-chamber container has been devised in which a weak seal portion is surely communicated and an alerting effect for mixing medicines contained in a plurality of chambers is achieved (see Patent Document 2). The idea of Patent Document 2 is to close a hanger hole of a container with a seal for confirmation of opening having a display portion that prompts mixing of a medicine.

JP-A-2-4671 Utility Model Registration No. 3074885

  However, the device of Patent Document 2 is not sufficient to prevent unmixed administration. This is because the general diameter of the hanger hole is not so large, and the seal for closing the hanger hole is inevitably small. Therefore, if the small seal is lost before communication, there is a high possibility that unmixed administration is performed as in the conventional case. In addition, since the flexible multi-chamber container containing the medicine may be used without being hung on the hanger (for example, when the medicine in the container is sucked with a syringe or the like), in such a case However, there is a high risk of unmixed administration.

Therefore, the present inventors have come up with the present invention as a result of intensive studies to solve the above-mentioned problems. That is, the present invention
(1) A plurality of chambers for storing medicines inside,
Partition means for partitioning the chambers and communicating with each other by pressing one of the chambers;
An outlet for discharging the medicine;
A flexible multi-chamber container provided with sealing means for sealing the puncture portion of the discharge port,
At least one of the chambers has removable covering means for covering at least a portion of the outer surface of the chamber, and the covering means and the sealing means are connected by a flexible connection. Chamber container.
(2) The flexible multi-chamber container according to (1), wherein the covering means covers the chamber provided with the discharge port, and the connecting portion is separated by pressing the chamber.
(3) The flexible multi-chamber container according to (1) or (2), wherein the covering means is provided with a caution display section for prompting mixing of the medicine.
(4) The flexible multi-chamber container according to any one of (1) to (3), wherein the covering means conceals at least a part of a content display unit provided in the chamber.
(5) The flexible multi-chamber container according to any one of (1) to (4), wherein the covering means is detachably bonded or welded to the chamber.
(6) The flexible multi-chamber container according to any one of (1) to (5), wherein the connection portion is a perforation.
(7) The flexible multi-chamber container according to (6), wherein the covering means and the sealing means are integrally formed of a flexible film.

  ADVANTAGE OF THE INVENTION According to this invention, it can prevent with the simple member that the chemical | medical agent accommodated in the flexible multi-chamber container is administered to a patient in the state before mixing.

Next, embodiments of the present invention will be described with reference to the drawings.
FIG. 1 is a front view showing an embodiment of the present invention.
FIG. 2 is a rear view of FIG.
FIG. 3 is a right side view of FIG.
FIG. 4 is a bottom view of FIG. 4A shows a state where the puncture portion is sealed with the sealing means, and FIG. 4B shows a state where the sealing means is removed.
FIG. 5 is a front view showing an embodiment of the present invention, and shows a state after the medicine is mixed and the covering means is removed.
FIG. 6 is a diagram showing a use situation of the embodiment of the present invention.

  As shown in FIGS. 1 to 4, the flexible multi-chamber container 1 of the present invention includes a container main body 2 and a lower chamber 20 that are composed of an upper chamber 10 and a lower chamber 20 that are partitioned by a partition means 30 that can communicate with each other. And at least a part of the surface of the lower chamber 20 is covered with the covering means 50, and the covering means 50 is a sealing means for sealing the puncture portion 41 of the discharge port 40. 60 is configured to be separably connected to 60 through a connection unit 70.

  The container body 2 is made of a flexible film, and the inside thereof is divided into an upper chamber 10 that stores the drug D1 and a lower chamber 20 that stores the drug D2 through partition means 30 that can communicate with each other. Its surroundings are sealed liquid-tight or air-tight. Examples of the sealing method include thermal welding, ultrasonic welding, adhesion, and the like, but the sealing method is not limited as long as the inside can be kept liquid-tight or air-tight. Examples of the material for forming the container body 2 include polyolefin resins such as polyethylene and polypropylene, polyvinyl chloride, PET (polyethylene terephthalate), EVA (ethylene vinyl acetate copolymer), EVOH (ethylene vinyl alcohol copolymer), and polyamide. , Polyvinylidene chloride, polyvinyl fluoride, polytrifluorochloroethylene, polyester, nylon, mixtures thereof, and laminates thereof, but have been used as medical materials and are contained in the container body 2 Any of them can be suitably used as long as there is no risk of elution into the drug without interacting with the drug. In this embodiment, both the drugs D1 and D2 are liquids, but either one may be a powder. As will be described later, when the partitioning means 30 is a weak seal that communicates with the chamber by pressing, it is preferable that at least one chamber contains a liquid agent. This is to generate a pressure necessary for communicating the weak seal by pressing the chamber containing the liquid agent.

  The partition means 30 is formed by a weak seal and communicates when the upper chamber 10 or the lower chamber 20 is pressed. Examples of the weak sealing method include a method in which a sheet made of a resin having a low compatibility with the resin forming the container main body 2 is sandwiched and welded. For example, when the container body 2 is made of a polyethylene resin, a weak seal that can be peeled relatively easily by sandwiching and welding a sheet made of a resin such as polypropylene that is not compatible with polyethylene. It can be. In addition to such a method, a method described in Patent Document 1 or a method of interposing a breakable bottomed tube can be employed. If the partitioning means 30 can be communicated in use, the method is as follows. There is no particular limitation.

  The lower chamber 20 is provided with a discharge port 40 that is used when discharging the mixed drug or injecting another drug into the container body 2. As shown in FIG. 4B, the discharge port 40 is provided with a puncture portion 41 into which an infusion needle or an injection needle is punctured. The puncture portion 41 is liquid-tight by the sealing means 60 until just before use. Or it is sealed hermetically. The sealing means 60 ensures that the portion to be punctured 41 is kept clean during manufacture and proves that the flexible multi-chamber container 1 is unused. Examples of the material for forming the discharge port 40 include polyolefin resins such as polyethylene and polypropylene, cyclic polyolefin, polyvinyl chloride, PET, EVA, EVOH, polyamide, polyvinylidene chloride, polyvinyl fluoride, polytrifluoroethylene, polyester, nylon, Examples include polystyrene, ABS resin, polycarbonate, methacrylic resin, polymethylpentene, mixtures thereof, and laminates thereof. However, they have been used as medical materials and interact with drugs contained in the container body 2. Any of them can be suitably employed as long as there is no fear of elution into the drug. For example, elastic material such as butyl rubber, silicone rubber, thermoplastic elastomer, silicone elastomer or the like can be suitably used as a material for forming the portion 41 to be punctured, but is not particularly limited as long as it can puncture an infusion needle or injection needle. .

  The sealing means 60 shown in FIGS. 1 to 4 is a flexible film and is attached to the discharge port 40 by heat welding, ultrasonic welding, adhesion, or the like, but the puncture portion 41 can be sealed in a liquid-tight or air-tight manner. If it exists, the attachment method will not be specifically limited. Also, as shown in FIG. 6C, when removing the sealing means 60 from the discharge port 40, it is easy to pinch the knob portion 61 and peel it off in the direction of arrow C. Examples of the forming material of the sealing means 60 include polyolefin resins such as polyethylene and polypropylene, polyvinyl chloride, PET, EVA, EVOH, polyamide, polyvinylidene chloride, polyvinyl fluoride, polytrifluoroethylene, polyester, nylon, and polychlorinated. Examples thereof include vinylidene, polyvinyl alcohol, a mixture thereof, a laminate thereof, and the like, but are not particularly limited as long as the resin has flexibility.

  A covering means 50 that covers at least a part of the outer surface of the lower chamber 20 is detachably attached to the outer surface of the lower chamber 20. Examples of the attaching method include adhesion and welding, but the method is not particularly limited as long as the covering means 50 can be peeled off. Further, the covering means 50 may cover substantially the entire one surface of the lower chamber 20. As the forming material of the covering means 50, the same material as that of the sealing means 60 can be suitably employed, and a film that can be delaminated (delaminated) may be used. By employing a film that can be peeled off as the covering means 50, a part of the layer of the covering means 50 remains in the lower chamber 20 when the covering means 50 is removed. For example, characters such as “opened” can be printed on this layer and concealed by a layer from which these characters can be removed.

  Further, as shown in FIG. 1, the covering means 50 is provided with a caution display section 80 for prompting the mixing of the medicines D1 and D2 during use, and either the upper chamber 10 or the lower chamber 20 is pushed during use. This causes the partition means 30 to communicate and prompts the user to perform the mixing operation of the drugs D1 and D2. In the caution display section 80 of FIG. 1, “Press here to mix medicine” is displayed, and the user is urged to perform the mixing operation by pressing the covering means 50. The contents and means are not particularly limited as long as they are urgently suggested, and may be schematic views.

  Further, as shown in FIGS. 1 and 5, a content display unit 90 is provided on the outer surface of the lower chamber 20 to display the amount and name of the medicine accommodated therein, and the covering means 50 displays the content display. At least a part of the portion 90 is concealed. The content display unit 90 includes a scale line 91 for displaying the remaining amount of the medicine when discharging the mixed medicine and a number 92 indicating the capacity. If the content display unit 90 is concealed, the user cannot know the remaining amount of the medicine. Therefore, it is necessary to pay attention to the covering means 50 that conceals the content display unit 90 and to perform a mixing operation. recognize. In addition to the scale line 91 and the number 92 indicating the capacity described above, the content display unit 90 may display information on the medicine accommodated in the medicine name, prescription, and the like. Further, the covering means may conceal substantially all of the content display means 90.

  The covering means 50 and the sealing means 60 are connected by a connecting portion 70, and the connecting portion 70 can be separated as necessary. The covering means 50 and the sealing means 60 shown in FIG. 1 are integrally formed of a flexible film, and a connecting portion 70 that connects them is a sewing machine formed on the boundary line between the covering means 50 and the sealing means 60. Eyes. Note that the connecting portion 70 is not necessarily a perforation, and the connecting method is not particularly limited as long as the covering means 50 and the sealing means 60 are detachably connected. Examples of other connection methods include adhesion, welding, engagement, and the like.

Next, a method of using the embodiment of the present invention will be described with reference to FIG.
(1) In a large hospital with a large number of hospital beds, first, as shown in FIG. 6A, a pharmacist or the like presses the lower chamber 20 in the direction of arrow A together with the covering means 50 at the dispensing unit 30. The weak seal is communicated, and the mixing operation of the drug D1 and the drug D2 is performed. When the mixing operation is performed, the connecting portion 70 is pulled as the covering means 50 is pushed, and the connecting portion 70 is broken at the perforation. It can be known whether or not the mixing of the medicine is completed by checking whether or not the connecting portion 70 is broken. The connecting portion 70 does not necessarily need to be separated at the same time as performing the mixing operation, and may be separated after performing the mixing operation.
(2) Next, as shown in FIG. 6 (b), the covering means 50 is pulled in the direction of arrow B to peel off from the lower chamber 20. This peeling operation may be performed at the dispensing part or at the bedside. However, if the pharmacist of the dispensing unit performs the mixing operation and is handed over to the bedside nurse with the covering means 50 attached, both the pharmacist and the nurse will double check whether or not the mixing operation is performed. be able to.
(3) Next, as shown in FIG. 6C, the knob 61 is pinched and the sealing means 60 is pulled in the direction of arrow C to peel off from the discharge port 40. Thereafter, the portion to be punctured 41 (not shown) is sterilized, and an infusion needle or the like is punctured to administer the mixed drug to the patient. In small hospitals with few beds, nurses often perform all work at the bedside.

  By the way, when the mixing means is forgotten and the covering means 50 remains as it is, when removing the sealing means 60, it is naturally noticed that the covering means 50 is connected to the sealing means 60. Therefore, since a user such as a nurse recognizes that there is some abnormality (unmixed), it is possible to effectively prevent drug administration before mixing.

FIG. 1 is a front view showing an embodiment of the present invention. FIG. 2 is a rear view of FIG. FIG. 3 is a right side view of FIG. FIG. 4 is a bottom view of FIG. 4A shows a state where the puncture portion is sealed with the sealing means, and FIG. 4B shows a state where the sealing means is removed. FIG. 5 is a front view showing an embodiment of the present invention, and shows a state after the medicine is mixed and the covering means is removed. FIG. 6 is a diagram showing a use situation of the embodiment of the present invention.

Explanation of symbols

1 Flexible multi-chamber container 10, 20 chambers (upper and lower chambers)
30 partition means 40 discharge port 41 puncture part 50 covering means 60 sealing means 70 connection part 80 attention display part 90 content display part D1, D2 medicine

Claims (7)

A plurality of chambers for containing medicines,
Partition means for partitioning the chambers and communicating with each other by pressing one of the chambers;
An outlet for discharging the medicine;
A flexible multi-chamber container provided with sealing means for sealing the puncture portion of the discharge port,
At least one of the chambers has removable covering means for covering at least a portion of the outer surface of the chamber, and the covering means and the sealing means are connected by a flexible connection. Chamber container.   The flexible multi-chamber container according to claim 1, wherein the covering means covers the chamber provided with the discharge port, and the connecting portion is separated by pressing the chamber.   The flexible multi-chamber container according to claim 1 or 2, wherein the covering means is provided with a caution display portion for prompting mixing of the medicine.   The flexible multi-chamber container according to any one of claims 1 to 3, wherein the covering means conceals at least a part of a content display section provided in the chamber.   The flexible multi-chamber container according to any one of claims 1 to 4, wherein the covering means is detachably bonded or welded to the chamber.   The flexible multi-chamber container according to claim 1, wherein the connection portion is a perforation. The flexible multi-chamber container according to claim 6, wherein the covering means and the sealing means are integrally formed of a flexible film.

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