JP2005053834A - Solubilizable cosmetic - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To prepare a solubilizable cosmetic good in humectancy, suppressing greasiness inherent in carnitine as an ingredient, giving the skin well-feeling touch, and good in usability and appearance (clearness, transparency). <P>SOLUTION: This solubilizable cosmetic contains (A) carnitine or a salt thereof and (B) one or more ingredients selected from polyoxyethylene methylglucosides and polyethylene glycols ≥600 in number-average molecular weight. <P>COPYRIGHT: (C)2005,JPO&NCIPI

Description

  The present invention relates to a cosmetic, and more particularly, to a solubilized cosmetic having excellent moisturizing properties without stickiness.

  Conventionally, solubilized transparent cosmetics such as lotions have common aging signs such as exfoliation of keratinocytes due to skin surface drying, appearance of wrinkles, tarmi and stains, loss of elasticity and elasticity. In order to improve the above, carnitine that increases the barrier function by increasing the thickness of the aging and thinned epidermis has been used as an aging skin improving agent (see, for example, Patent Documents 1 to 3). However, since carnitine has a so-called betaine structure that has a quaternary ammonium group and a carboxyl group in the molecule, when carnitine is blended in solubilized cosmetics with few blends of oils, etc., stickiness is strongly felt on the touch. It had the problem of being easy.

Japanese Patent Laid-Open No. 11-29457 JP 2001-240538 A JP 2001-247443 A

  In view of the above circumstances, the present inventor has intensively studied to reduce the stickiness of carnitine and obtain a cosmetic with good usability, and as a result, one or more selected from the group consisting of polyoxyethylene methyl glucoside and polyethylene glycol In combination with carnitine, it has good moisturizing properties, gives a good feeling to the skin, and can easily produce a solubilized cosmetic with excellent usability and good appearance. The present invention has been completed.

  Accordingly, an object of the present invention is to provide a solubilized cosmetic that has a good moisturizing property, gives a feeling of feeling to the skin, is excellent in usability, and has a good appearance (clear and transparent). There is.

  The above-described object is achieved by a solubilized cosmetic material comprising carnitine or a salt thereof and one or more selected from the group consisting of polyoxyethylene methyl glucoside and polyethylene glycol.

  That is, the present invention is characterized by containing (A) carnitine or a salt thereof and (B) one or more selected from the group consisting of polyoxyethylene methyl glucoside and polyethylene glycol having a number average molecular weight of 600 or more. It relates to a solubilized cosmetic.

  Preferably, the component (B) is one or more selected from the group consisting of polyoxyethylene methyl glucoside having an ethylene oxide addition mole number of 10 to 30 and polyethylene glycol having a number average molecular weight of 1000 to 8000. is there.

  According to the present invention, there is provided a solubilized cosmetic that has good moisturizing properties, has less stickiness, gives a feeling of feeling to the skin, has excellent usability, and has a good appearance (clear and transparent). can do.

  Hereinafter, embodiments of the present invention will be described in detail.

(A) Carnitine used in the present invention means γ-amino-β-hydroxybutyrobetaine (3-Carboxy-2-Hydroxy-N, N—N, trimethyl-1-propadium hydroxide, C ₇ H ₁₅ NO ₃ ), widely present as a basic component of skeletal muscle, usually extracted from pork, calf and horse meat, involved in fatty acid transport to mitochondria in the form of acylcarnitine, where fatty acid oxidation is In addition to the promoting action, it is known to act to promote fatty acid synthesis. Carnitine is a water-soluble substance, is an optical isomer in terms of chemical structure, and includes D-type, L-type, and DL-type that is a mixture thereof, any of which can be used in the present invention.

  Carnitine used as the component (A) in the present invention is a known substance and is used in medicines, foods, etc., and is obtained, for example, by synthesis. Moreover, carnitine can be obtained by neutralizing carnitine chloride, which is a hydrochloride salt of carnitine, with an alkali component.

  Examples of the salt of carnitine used as the component (A) used in the present invention include inorganic salts such as hydrochloride, sulfate and nitrate, and organic acid salts such as acetate, citrate, nicotinate and salicylate. Carnitine chloride is preferred from the viewpoint of versatility and effects.

  The content of the entire component (A) used in the present invention is preferably 0.01 to 10% by mass (hereinafter abbreviated as%), particularly preferably 0.1 to 5%, based on the total amount of the cosmetic. It is. If it is within the range, the moisturizing effect is particularly high, the stickiness suppressing effect is particularly excellent, and the skin feel is also good.

  Polyoxyethylene methyl glucoside used as component (B) in the present invention and polyethylene glycol having a molecular weight of 600 or more are also known materials for cosmetics. Examples of the polyethylene methyl glucoside include NIKKOL BMG-10, NIKKOL BMG-20 (manufactured by Nikko Chemicals), Glucam E-10, and Glucam E-20 (manufactured by Ikeda Bussan). Polyethylene glycol having a number average molecular weight of 200 to 20,000 is sold by Sanyo Chemical, Nippon Oil, Daiichi Kogyo Seiyaku, Lion, and others.

  The polyoxyethylene methyl glucoside preferably has an ethylene oxide addition mole number of 10 to 30, and more preferably an ethylene oxide addition mole number of 15 to 25. The polyethylene glycol having a number average molecular weight of 600 or more is preferably a number average molecular weight of 1000 to 8000, more preferably 4000 to 6000. If it is within the range, the stickiness-inhibiting effect is particularly excellent and the skin feel is also good.

  The content of the entire component (B) used in the present invention is preferably 0.001 to 10%, particularly preferably 0.1 to 5%, based on the total amount of the cosmetic. If it is within the range, the stickiness suppressing effect is particularly excellent, and it is advantageous in terms of cost.

  The cosmetic of the present invention has the above-described components as essential components, but other components such as an anionic surfactant and an amphoteric surfactant are included in the composition as long as the object of the present invention is not impaired. Agents, nonionic surfactants, adhesives, preservatives, fragrances, moisturizers, physiologically active ingredients, salts, solvents, antioxidants, chelating agents, neutralizing agents, pH adjusters, insect repellents, enzymes, etc. Components can be appropriately blended.

  Specific examples of other compounding components are shown below, but are not limited thereto.

  Examples of the anionic surfactant include linear or branched fatty acid salts, α-acyl sulfonates, alkyl sulfonates, alkyl allyl sulfonates, alkyl naphthalene sulfonates, alkyl sulfates, alkyl ether sulfates, Alkylamide sulfate, polyoxyethylene alkyl ether sulfate, polyoxyethylene alkylamide ether sulfate, alkyl phosphate, alkylamide phosphate, alkyloylalkyl taurine salt, N-acyl amino acid salt, sulfosuccinate, Examples thereof include fluoroalkyl phosphate esters.

  Examples of amphoteric surfactants include glycine type, aminopropionic acid type, carboxybetaine type, sulfobetaine type, sulfonic acid type, sulfuric acid type, and phosphoric acid type.

  Nonionic surfactants include fatty acid alkanolamide, polyoxyethylene hydrogenated castor oil, polyoxyethylene sorbitan fatty acid ester, polyoxyethylene alkyl ether, polyoxyethylene alkyl ester, sucrose fatty acid ester, polyglycerin fatty acid ester, alkyl An amine oxide etc. are mentioned.

  Examples of the oil agent include volatile and non-volatile oil agents, solvents, and resins that are usually used in cosmetics, and may be in the form of liquid, paste, or solid at room temperature. Examples of oils include higher alcohols such as cetyl alcohol, isostearyl alcohol, lauryl alcohol, hexadecyl alcohol, octyldodecanol, fatty acids such as isostearic acid, undecylenic acid, oleic acid, myristyl myristate, hexyl laurate, myristine Octyldodecyl acid, decyl oleate, isopropyl myristate, hexyl decyl dimethyloctanoate, glyceryl monostearate, glyceryl trioctanoate, diethyl phthalate, ethylene glycol monostearate, octyl oxystearate, cholesteryl stearate, Cholesterol esters such as cholesteryl oleate and branched fatty acid cholesteryl, hydrocarbons such as liquid paraffin, petroleum jelly and squalane, lanoli Waxes such as reduced lanolin, carnauba wax, mink oil, cacao butter, palm oil, palm kernel oil, camellia oil, sesame oil, castor oil, olive oil, dimethylpolysiloxane, cyclic dimethylpolysiloxane, methylphenylpolysiloxane, etc. Silicone oil etc. are mentioned.

  Examples of powders include red No. 201, yellow No. 4, blue No. 1 and black No. 401 pigments, yellow No. 4 Al lake, yellow No. 203 Ba lake and other lake pigments, nylon powder, silk powder and silicone powder. , Cellulose powder, silicone elastomer spherical powder, resin such as polyethylene powder, yellow iron oxide, red iron oxide, chromium oxide, carbon black, colored pigments such as ultramarine and bitumen, white pigments such as zinc oxide and titanium oxide, talc, Body pigments such as mica, sericite and kaolin, pigments such as pearl pigments such as titanium mica, metal salts such as barium sulfate, calcium carbonate, magnesium carbonate and magnesium silicate, inorganic powders such as silica and alumina, bentonite, smectite, Examples thereof include boron nitride. There are no particular restrictions on the shape of these powders, such as spherical shape, rod shape, needle shape, plate shape, irregular shape, flake shape, and spindle shape.

  Examples of the physiologically active ingredient include substances that impart some physiological activity to the skin when applied to the skin. For example, anti-aging agents, UV protection agents, squeeze agents, antioxidants, moisturizers, blood circulation promoters, antibacterial agents, bactericides, desiccants, cooling agents, warming agents, vitamins, amino acids, wound healing promoters , Stimulation mitigating agents, analgesics, cell activators, enzyme components and the like.

The solubilized cosmetic of the present invention is a cosmetic having a transparent to translucent appearance, and preferably has a light transmittance of 80% or more at a wavelength of 700 nm. These solubilized cosmetics can be produced according to a conventional method. Moreover, the solubilized cosmetics of the present invention can be suitably used as basic cosmetics, body cosmetics and the like. For example, it is useful as skin conditioning lotion, wiping lotion, soft lotion, acne treatment lotion, after shave lotion, two-layer conditioning lotion, hair tonic and the like. The cosmetics of the present invention are not limited to general cosmetics, but include quasi drugs, designated quasi drugs, topical drugs and the like.

Examples 1-9, Comparative Examples 1-6
Hereinafter, the present invention will be specifically described with reference to Examples and Comparative Examples. The present invention is not limited to these examples.

  The solubilized cosmetics obtained in Examples and Comparative Examples have a transmittance of 80% or more when the transmittance of distilled water is 100% when measured with a spectrophotometer at a wavelength of 700 nm. The sensory evaluation method used in the present invention is described below.

[sensory evaluation]
Lotions having the compositions shown in Tables 1 and 2 were prepared by a conventional method. This was used by 10 panelists, and the moisturizing feeling and stickiness were evaluated according to the following evaluation criteria, and the total score of all panelists was used as the evaluation result. Accordingly, the higher the score for each item, the more “moisturizing feeling” or “no stickiness”. The results are shown in Table 2.

<Moisturizing feeling>
Evaluation criteria Score very moisturizing 5
I feel quite moisturizing 4
I feel a little moisturizing 3
I hardly feel moisturizing 2
Does not feel moisturizing 1

<Stickiness>
Evaluation criteria Do not feel sticky points 5
Almost no stickiness 4
I feel a little sticky 3
I feel quite sticky 2
I feel very sticky 1

  From Table 2, Examples 1-9 which are the cosmetics of this invention should have little moisturizing feeling compared with the cosmetics of Comparative Examples 1-6 which do not satisfy the structural requirements of this invention. I understand.

Example 10
A lotion having the composition shown below was prepared by a conventional method. As a result of evaluation on the moisturizing feeling and stickiness, it was confirmed that the moisturizing feeling was good, the stickiness was small, and the feeling of use was excellent.

(Lotion) (mass%)
Carcinine 1.0
Ethanol 10.0
Polyoxyethylene hydrogenated castor oil (60 EO) 1.0
Glycerin 3.0
1,3-butylene glycol 2.0
Dipropylene glycol 3.0
Polyethylene glycol 1500 1.0
POE (10) methyl glucoside 1.0
Carboxyvinyl polymer 0.1
Xanthan gum 0.1
Sodium hydrogen phosphate 0.05
Potassium dihydrogen phosphate 0.05
Edetate disodium 0.05
Methylparaben 0.1
Fragrance 0.05
Purified water Remaining amount of 100

Example 11
A skin conditioning lotion having the composition shown below was prepared by a conventional method. As a result of evaluation on the moisturizing feeling and stickiness, it was confirmed that the moisturizing feeling was good, the stickiness was small, and the feeling of use was excellent.

(Skin conditioning lotion) (mass%)
Carnitine 1.0
Polyoxyethylene hydrogenated castor oil (60 EO) 1.0
Polyethylene glycol 6000 1.0
POE (20) methyl glucoside 1.0
Carboxyvinyl polymer 0.15
Fragrance 0.05
Methyl paraoxybenzoate 0.1
Purified water Remaining amount of 100

Example 12
An after shave lotion having the composition shown below was prepared by a conventional method. This after-shave lotion, when used after shaving, had a smooth finish, little stickiness, and a refreshing and refreshing feel.

(After Shave Lotion) (mass%)
Carcinine 2.0
Ethanol 30.0
Fragrance 0.05
Isopropylmethylphenol 0.01
Vitamin A 0.05
Polyoxyethylene hydrogenated castor oil (60 EO) 1.0
Polyethylene glycol 4000 1.0
POE (20) methyl glucoside 1.0
Carboxyvinyl polymer 0.15
Alkyl-modified carboxyvinyl polymer 0.15
Xanthan gum 0.1
Purified water Remaining amount of 100

Example 13
A two-layer conditioning lotion having the composition shown below was prepared by a conventional method. In this two-layer conditioning lotion, the required number of shakings was four times, and the separated powder layer and aqueous layer were uniformly mixed to form a suspension. Furthermore, 1 hour after standing, a beautiful appearance was clearly separated into two layers of a transparent water layer portion and a light red powder layer portion. In addition, this two-layer conditioning lotion did not feel sticky when used, and gave a moist finish.

(Two-layer conditioning lotion) (mass%)
Carnitine 1.0
Ethyl alcohol 10.0
Fragrance 0.1
Polyoxyethylene hydrogenated castor oil (60 EO) 1.0
Glycerin 3.0
Zinc sulfate 0.3
Zinc flower 1.0
Bengala 0.01
Talc 1.0
Sodium carbonate 0.2
Polyethylene glycol 4000 1.0
POE (20) methyl glucoside 1.0
Carboxyvinyl polymer 0.15
Alkyl-modified carboxyvinyl polymer 0.15
Purified water Remaining amount of 100

Example 14
A hair tonic having the composition shown below was prepared by a conventional method. This hair artic finished with a moist and smooth scalp and hair, no stickiness, and a good feel.

(Heartnic) (mass%)
Carnitine 0.5
Ethanol 30.0
Polyoxyethylene hydrogenated castor oil (60 EO) 1.0
Estradiol 0.001
Fragrance 0.1
D-pantothenyl alcohol 0.1
Polyethylene glycol 4000 1.0
POE (20) methyl glucoside 1.0
Carboxyvinyl polymer 0.15
Purified water Remaining amount of 100

  In addition, the fragrance | flavor used in the said Example is a thing of the following fragrance | flavor prescription.

As described above, the present invention contains (A) carnitine or a salt thereof and (B) one or more selected from the group consisting of polyoxyethylene methyl glucoside and polyethylene glycol having a number average molecular weight of 600 or more. As for the cosmetics characterized by the above, it is possible to obtain cosmetics with excellent moisture retention, low stickiness, good feeling on the skin, excellent usability, and good appearance (clear, transparent). .
Moreover, the cosmetics of the present invention can be suitably used as basic cosmetics, body cosmetics and the like. The cosmetics of the present invention are not limited to general cosmetics, but include quasi drugs, designated quasi drugs, topical drugs and the like.

Claims (2)

(A) Carnitine or a salt thereof, and (B) one or more selected from the group consisting of polyoxyethylene methyl glucoside and polyethylene glycol having a number average molecular weight of 600 or more. . The component (B) is at least one selected from the group consisting of polyoxyethylene methyl glucoside having an ethylene oxide addition mole number of 10 to 30 and polyethylene glycol having a number average molecular weight of 1000 to 8000. Solubilized cosmetics.