JP2005030927A5 - - Google Patents

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Publication number
JP2005030927A5
JP2005030927A5 JP2003271084A JP2003271084A JP2005030927A5 JP 2005030927 A5 JP2005030927 A5 JP 2005030927A5 JP 2003271084 A JP2003271084 A JP 2003271084A JP 2003271084 A JP2003271084 A JP 2003271084A JP 2005030927 A5 JP2005030927 A5 JP 2005030927A5
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JP
Japan
Prior art keywords
microarray
biorelevant
molecule
linear
related molecular
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Pending
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JP2003271084A
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Japanese (ja)
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JP2005030927A (en
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Priority to JP2003271084A priority Critical patent/JP2005030927A/en
Priority claimed from JP2003271084A external-priority patent/JP2005030927A/en
Priority to EP04746892A priority patent/EP1643249A4/en
Priority to PCT/JP2004/009423 priority patent/WO2005003769A1/en
Priority to US10/563,232 priority patent/US20060246573A1/en
Publication of JP2005030927A publication Critical patent/JP2005030927A/en
Publication of JP2005030927A5 publication Critical patent/JP2005030927A5/ja
Pending legal-status Critical Current

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すなわち、本発明を概説すれば、本発明の第１の発明は、第１部材と第２部材との間に生体関連分子を担持する生体関連分子マイクロアレイであって、
前記第１部材もしくは前記第２部材のいずれか一方において、他方の部材に対する接触面に複数の溝を並列形成して、反応領域となる空間を複数設け、当該空間の内部に生体関連分子を均等に展開したことを特徴とする。 That is, when the present invention is outlined, the first invention of the present invention is a biologically relevant molecular microarray carrying biologically relevant molecules between the first member and the second member,
In either one of the first member and the second member, a plurality of grooves are formed in parallel on the contact surface with respect to the other member to provide a plurality of spaces as reaction regions, and biologically related molecules are evenly distributed inside the space. It is characterized by having expanded to .

更に、本発明の第２の発明は、第１部材と第２部材との間に生体関連分子を担持する生体関連分子マイクロアレイであって、
前記第１部材および前記第２部材の互いの接触面に複数の溝を並列形成して、反応領域となる空間を複数設け、当該空間の内部に生体関連分子を均等に展開したことを特徴とする。 Furthermore, the second invention of the present invention is a bio-related molecule microarray carrying a bio-related molecule between the first member and the second member,
A plurality of grooves are formed in parallel on the contact surfaces of the first member and the second member, a plurality of spaces serving as reaction regions are provided , and bio-related molecules are evenly developed inside the space. To do.

Claims (7)

第１部材と第２部材との間に生体関連分子を担持する生体関連分子マイクロアレイであって、
前記第１部材もしくは前記第２部材のいずれか一方において、他方の部材に対する接触面に複数の溝を並列形成して、反応領域となる空間を複数設け、当該空間の内部に生体関連分子を均等に展開してある生物関連分子マイクロアレイ。 A biorelevant molecule microarray carrying a biorelevant molecule between a first member and a second member,
In one of the first member or the second member, in parallel forming a plurality of grooves in the contact surface to the other member, only a plurality set the space of a reaction zone, a biologically relevant molecule in the interior of the space Biologically related molecular microarrays that are evenly deployed . 第１部材と第２部材との間に生体関連分子を担持する生体関連分子マイクロアレイであって、
前記第１部材および前記第２部材の互いの接触面に複数の溝を並列形成して、反応領域となる空間を複数設け、当該空間の内部に生体関連分子を均等に展開してある生物関連分子マイクロアレイ。 A biorelevant molecule microarray carrying a biorelevant molecule between a first member and a second member,
Wherein the first member and in parallel a plurality of grooves on the mutual contact surfaces of the second member, only multiple set of spaces a reaction zone, are evenly expand the biologically relevant molecule in the interior of the space organism Related molecular microarrays. 第１部材と第２部材との間に生体関連分子を担持する生体関連分子マイクロアレイであって、
前記第１部材には、前記第２部材に対する接触面に複数の線形凸部を並列形成し、
前記第２部材には、前記第１部材に対する接触面に前記線形凸部と一対一に嵌合可能な複数の線形溝部を並列形成し、
前記線形凸部と前記線形溝部とを嵌合させつつ、前記第１部材と前記第２部材とを当接させたとき、前記線形凸部と前記線形溝部との間に反応領域となる空間が形成されるように構成してある生物関連分子マイクロアレイ。 A biorelevant molecule microarray carrying a biorelevant molecule between a first member and a second member,
In the first member, a plurality of linear convex portions are formed in parallel on the contact surface with respect to the second member,
In the second member, a plurality of linear grooves that can be fitted in one-to-one with the linear protrusions on the contact surface with respect to the first member are formed in parallel.
When the first member and the second member are brought into contact with each other while fitting the linear convex portion and the linear groove portion, a space serving as a reaction region is formed between the linear convex portion and the linear groove portion. Biologically associated molecular microarray configured to be formed. 前記反応領域と外部とを連通可能とし、前記反応領域に試料を供給する試料供給口と反応領域から試料を回収する試料回収口とを設けてある請求項１〜３の何れか一項に記載の生体関連分子マイクロアレイ。 The reacting region and outside the can communicate, according to any one of claims 1 to 3 and a sample collection port is provided to recover the sample from the sample supply port and the reaction region for supplying the sample to the reaction area Bio-related molecular microarray. 前記第１部材および前記第２部材のうち少なくとも何れか一方を構成する基材が、ポリジメチルシロキサン、もしくは、ポリメタクリル酸メチルなど透明シリコンゴムあるいはプラスチック樹脂である請求項１〜４の何れか一項に記載の生体関連分子マイクロアレイ。   The base material constituting at least one of the first member and the second member is a transparent silicon rubber such as polydimethylsiloxane or polymethyl methacrylate or a plastic resin. The bio-related molecular microarray according to Item. 生体関連分子を担持する生体関連分子マイクロアレイであって、
複数の線状反応領域を並設したマイクロアレイ本体を有する生体関連分子マイクロアレイ A biorelevant molecular microarray carrying biorelevant molecules,
Biologically related molecular microarray having a microarray body with a plurality of linear reaction regions arranged side by side 前記マイクロアレイ本体を構成する基材が、ポリジメチルシロキサン、もしくは、ポリメタクリル酸メチルなど透明シリコンゴムあるいはプラスチック樹脂である請求項６に記載の生体関連分子マイクロアレイ。   The bio-related molecular microarray according to claim 6, wherein the base material constituting the microarray body is a transparent silicon rubber or plastic resin such as polydimethylsiloxane or polymethyl methacrylate.
JP2003271084A 2003-07-04 2003-07-04 Organism-related molecule microarray Pending JP2005030927A (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2003271084A JP2005030927A (en) 2003-07-04 2003-07-04 Organism-related molecule microarray
EP04746892A EP1643249A4 (en) 2003-07-04 2004-07-02 Bio-chip
PCT/JP2004/009423 WO2005003769A1 (en) 2003-07-04 2004-07-02 Bio-chip
US10/563,232 US20060246573A1 (en) 2003-07-04 2004-07-02 Bio-chip

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2003271084A JP2005030927A (en) 2003-07-04 2003-07-04 Organism-related molecule microarray

Publications (2)

Publication Number Publication Date
JP2005030927A JP2005030927A (en) 2005-02-03
JP2005030927A5 true JP2005030927A5 (en) 2006-04-06

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Application Number Title Priority Date Filing Date
JP2003271084A Pending JP2005030927A (en) 2003-07-04 2003-07-04 Organism-related molecule microarray

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JP (1) JP2005030927A (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPWO2007040219A1 (en) * 2005-10-04 2009-04-16 株式会社アイ・ピー・ビー Nanoarray DNA chip
JP2007283437A (en) * 2006-04-17 2007-11-01 Sumitomo Bakelite Co Ltd Micro-passage forming method to plastics, and plastic biochip or micro-analysis chip manufactured by using the method
JP5831867B2 (en) * 2011-03-30 2015-12-09 国立大学法人島根大学 Technology for visualizing substance interactions in real time

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