JP2004533848A - ヒトアミノペプチダーゼnの調節 - Google Patents

ヒトアミノペプチダーゼnの調節 Download PDF

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Publication number
JP2004533848A
JP2004533848A JP2003512404A JP2003512404A JP2004533848A JP 2004533848 A JP2004533848 A JP 2004533848A JP 2003512404 A JP2003512404 A JP 2003512404A JP 2003512404 A JP2003512404 A JP 2003512404A JP 2004533848 A JP2004533848 A JP 2004533848A
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JP
Japan
Prior art keywords
aminopeptidase
polypeptide
polynucleotide
activity
test compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2003512404A
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English (en)
Japanese (ja)
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JP2004533848A5 (enExample
Inventor
アレックス・スモリアー
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer Healthcare AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Bayer Healthcare AG filed Critical Bayer Healthcare AG
Publication of JP2004533848A publication Critical patent/JP2004533848A/ja
Publication of JP2004533848A5 publication Critical patent/JP2004533848A5/ja
Pending legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Pulmonology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
JP2003512404A 2001-07-10 2002-06-28 ヒトアミノペプチダーゼnの調節 Pending JP2004533848A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30369301P 2001-07-10 2001-07-10
PCT/EP2002/007157 WO2003006646A1 (en) 2001-07-10 2002-06-28 Regulation of human aminopeptidase n

Publications (2)

Publication Number Publication Date
JP2004533848A true JP2004533848A (ja) 2004-11-11
JP2004533848A5 JP2004533848A5 (enExample) 2006-01-05

Family

ID=23173257

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2003512404A Pending JP2004533848A (ja) 2001-07-10 2002-06-28 ヒトアミノペプチダーゼnの調節

Country Status (4)

Country Link
US (1) US7129077B2 (enExample)
EP (1) EP1407010A1 (enExample)
JP (1) JP2004533848A (enExample)
WO (1) WO2003006646A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040146516A1 (en) * 1999-06-17 2004-07-29 Utah Ventures Ii L.P. Lumen-exposed molecules and methods for targeted delivery
US20030119036A1 (en) * 2001-10-31 2003-06-26 Millennium Pharmaceuticals, Inc. Methods of using 48149, a human aminopeptidase family member
WO2005007825A2 (en) * 2003-07-12 2005-01-27 Isis Pharmaceuticals, Inc. Modulation of aminopeptidase n expression
WO2007087370A2 (en) * 2006-01-25 2007-08-02 Caprion Pharmaceuticals, Inc. Tat-038 and methods of assessing and treating cancer
GB0803076D0 (en) * 2008-02-20 2008-03-26 Univ Ghent Mucosal Membrane Receptor and uses thereof
JP2019503201A (ja) * 2015-11-25 2019-02-07 ウェイク フォーレスト ユニバーシティ ヘルス サイエンシーズWake Forest University Health Sciences 肺炎球菌阻害因子組成物及びその使用の方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU9477398A (en) * 1997-09-10 1999-03-29 Burnham Institute, The Methods of identifying molecules that home to angiogenic vasculature in tumors
CA2408105A1 (en) * 2000-05-04 2001-11-08 Sugen, Inc. Novel proteases
US6927056B2 (en) * 2001-09-06 2005-08-09 Incyte Corporation Proteases
US20020164766A1 (en) * 2000-10-20 2002-11-07 Rajasekhar Bandaru 57406, a novel human metalloprotease family member and uses thereof
US20040063107A1 (en) * 2001-05-04 2004-04-01 Plowman Gregory D. Novel proteases

Also Published As

Publication number Publication date
US20040241156A1 (en) 2004-12-02
WO2003006646A1 (en) 2003-01-23
EP1407010A1 (en) 2004-04-14
US7129077B2 (en) 2006-10-31

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