JP2004530635A5 - - Google Patents

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Publication number
JP2004530635A5
JP2004530635A5 JP2002537256A JP2002537256A JP2004530635A5 JP 2004530635 A5 JP2004530635 A5 JP 2004530635A5 JP 2002537256 A JP2002537256 A JP 2002537256A JP 2002537256 A JP2002537256 A JP 2002537256A JP 2004530635 A5 JP2004530635 A5 JP 2004530635A5
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JP
Japan
Prior art keywords
noxi
nac
shows
phosphorylation
jnk
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Pending
Application number
JP2002537256A
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English (en)
Japanese (ja)
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JP2004530635A (ja
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Publication date
Priority claimed from GB0026254A external-priority patent/GB2368339B/en
Application filed filed Critical
Publication of JP2004530635A publication Critical patent/JP2004530635A/ja
Publication of JP2004530635A5 publication Critical patent/JP2004530635A5/ja
Pending legal-status Critical Current

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JP2002537256A 2000-10-26 2001-10-25 多成分抗酸化性化合物、該化合物を含有する薬学的組成物、および酸化的ストレスを軽減または防止するためのそれらの使用 Pending JP2004530635A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0026254A GB2368339B (en) 2000-10-26 2000-10-26 Complex incorporating a plurality of antioxidants
PCT/IL2001/000984 WO2002034202A2 (en) 2000-10-26 2001-10-25 Multi-component antioxidant compounds, pharmaceutical compositions containing same and their use for reducing or preventing oxidative stress

Publications (2)

Publication Number Publication Date
JP2004530635A JP2004530635A (ja) 2004-10-07
JP2004530635A5 true JP2004530635A5 (https=) 2005-04-21

Family

ID=9902037

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2002537256A Pending JP2004530635A (ja) 2000-10-26 2001-10-25 多成分抗酸化性化合物、該化合物を含有する薬学的組成物、および酸化的ストレスを軽減または防止するためのそれらの使用

Country Status (8)

Country Link
US (3) US20070287662A1 (https=)
EP (1) EP1333809A4 (https=)
JP (1) JP2004530635A (https=)
AU (1) AU2002212661A1 (https=)
CA (1) CA2427005A1 (https=)
GB (1) GB2368339B (https=)
IL (2) IL155497A0 (https=)
WO (1) WO2002034202A2 (https=)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2368339B (en) 2000-10-26 2002-09-18 Yissum Res Dev Co Complex incorporating a plurality of antioxidants
US20050032708A1 (en) * 2001-09-27 2005-02-10 Bush Ashley I. Modulation of physiological processes and agents useful for same
AU2003247144B2 (en) * 2002-08-02 2007-11-29 Mor Research Applications Ltd. Treatment of multiple sclerosis with brain targeted anti oxidant compounds
AU2004293477A1 (en) * 2003-11-25 2005-06-09 University Of Rochester Compounds for delivering amino acids or peptides with antioxidant activity into mitochondria and use thereof
US8895032B2 (en) 2009-03-27 2014-11-25 Central Michigan University Dendritic nano-antioxidants
US10052299B2 (en) 2009-10-30 2018-08-21 Retrotope, Inc. Alleviating oxidative stress disorders with PUFA derivatives
AU2012208283B2 (en) 2011-01-20 2017-01-05 Oneday - Biotech And Pharma Ltd. Antioxidant, anti-inflammatory, anti-radiation, metal chelating compounds and uses thereof
JP6106157B2 (ja) 2011-04-26 2017-03-29 レトロトップ、 インコーポレイテッドＲｅｔｒｏｔｏｐｅ， Ｉｎｃ． 神経変性障害および筋疾患に関与するｐｕｆａ
KR102112087B1 (ko) 2011-04-26 2020-05-18 레트로토프 인코포레이티드 에너지 프로세싱 손상 장애 및 미토콘드리아 결함
WO2012148930A2 (en) 2011-04-26 2012-11-01 Retrotope, Inc. Oxidative retinal diseases
JP6145087B2 (ja) 2011-04-26 2017-06-07 レトロトップ、 インコーポレイテッドＲｅｔｒｏｔｏｐｅ， Ｉｎｃ． Ｐｕｆａ酸化関与障害
CA2879019A1 (en) * 2012-07-23 2014-01-30 Oneday - Biotech And Pharma Ltd. Glutathione-elevating compositions and uses thereof
WO2014016837A1 (en) * 2012-07-25 2014-01-30 Oneday - Biotech And Pharma Ltd. Compositions and methods for increasing carnitine level in muscle tissues
WO2016009341A1 (en) 2014-07-14 2016-01-21 Radikal Therapeutics Inc. Thioredoxin mimetic prodrugs and uses thereof
EP3950649A1 (en) 2015-11-23 2022-02-09 Retrotope, Inc. Site-specific isotopic labeling of 1, 4-diene systems
IL295783B2 (en) 2020-02-21 2026-03-01 Retrotope Inc Processes for isotopic alteration of polyunsaturated fatty acids and their derivatives
US12109194B2 (en) 2021-02-05 2024-10-08 Biojiva Llc Synergistic combination therapy for treating ALS

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4738841A (en) * 1985-08-28 1988-04-19 Repligen Corporation Use of thioredoxin, thioredoxin-derived, or thioredoxin-like dithiol peptides in hair care preparations
US4966848A (en) * 1988-02-08 1990-10-30 The General Hospital Corporation Isolation, purification, characterization, cloning and sequencing of N α-acetyltransferase
KR0141693B1 (ko) * 1988-08-12 1998-06-15 나까무라 하루후미 펩티드 유도체 및 항치매제
US5223421A (en) * 1989-10-25 1993-06-29 The General Hospital Corporation Identification of methionine Nα-acetyltransferase
IT1243911B (it) * 1990-11-19 1994-06-28 Zambon Spa Composizioni per la terapia mucolitica
US5464825A (en) * 1991-03-14 1995-11-07 Cornell Research Foundation, Inc. Raising glutathione equivalent levels using N-acyl glutathione monoesters
US5272252A (en) * 1991-11-04 1993-12-21 Merrell Dow Pharmaceuticals Inc. Synthetic lung surfactant having antioxidant properties
US5869615A (en) * 1994-01-03 1999-02-09 Washington University Modified complement proteases
US5688489A (en) * 1995-09-15 1997-11-18 Resolution Pharmaceuticals, Inc. Non-receptor mediated imaging agents
SE9503679D0 (sv) * 1995-10-20 1995-10-20 Pharmacia Ab Antioxidants
US5744593A (en) * 1996-02-15 1998-04-28 Heska Corporation Parasitic helminth larval thiol specific antioxidant proteins and nucleic acid molecules
US5985261A (en) * 1996-06-28 1999-11-16 National Jewish Medical And Research Center Use of thioredoxin-like molecules for induction of MnSOD to treat oxidative damage
US5874468A (en) * 1996-12-26 1999-02-23 Yissum Brain targeted low molecular weight hydrophobic antioxidant compounds
US5906811A (en) * 1997-06-27 1999-05-25 Thione International, Inc. Intra-oral antioxidant preparations
EP1068239A2 (en) 1998-03-31 2001-01-17 University Of Cincinnati Antioxidant peptides derived from apolipoprotein a-iv
US6686443B1 (en) * 2000-05-26 2004-02-03 The Regents Of The University Of California Chemical reagents for formation of disulfide bonds in peptides
SV2003000617A (es) 2000-08-31 2003-01-13 Lilly Co Eli Inhibidores de la proteasa peptidomimetica ref. x-14912m
GB2368339B (en) 2000-10-26 2002-09-18 Yissum Res Dev Co Complex incorporating a plurality of antioxidants
US20030109457A1 (en) * 2001-10-25 2003-06-12 Yissum Research Development Company Of The Hebrew University Of Jerusalem Multi-component antioxidant compounds, pharmaceutical compositions containing same and their use for reducing or preventing oxidative stress

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