JP2004529642A - 薬物およびプロドラッグの送達系としてのアミノ酸輸送体ａｔｂ０，＋の利用 - Google Patents

薬物およびプロドラッグの送達系としてのアミノ酸輸送体ａｔｂ０，＋の利用 Download PDF

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Publication number
JP2004529642A
JP2004529642A JP2002580865A JP2002580865A JP2004529642A JP 2004529642 A JP2004529642 A JP 2004529642A JP 2002580865 A JP2002580865 A JP 2002580865A JP 2002580865 A JP2002580865 A JP 2002580865A JP 2004529642 A JP2004529642 A JP 2004529642A
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Prior art keywords
atb
compound
transport
carnitine
amino acids
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JP2002580865A
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Japanese (ja)
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JP2004529642A5 (https=
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バディベル ギャナパシー
貴弘 畠中
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Chugai Pharmaceutical Co Ltd
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Chugai Pharmaceutical Co Ltd
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Publication of JP2004529642A publication Critical patent/JP2004529642A/ja
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • General Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2002580865A 2001-04-13 2002-04-12 薬物およびプロドラッグの送達系としてのアミノ酸輸送体ａｔｂ０，＋の利用 Withdrawn JP2004529642A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US28332601P 2001-04-13 2001-04-13
US30616801P 2001-07-19 2001-07-19
PCT/JP2002/003678 WO2002083060A2 (en) 2001-04-13 2002-04-12 Use of amino acid transporter atb0,+ as a delivery system for drugs and prodrugs

Publications (2)

Publication Number Publication Date
JP2004529642A true JP2004529642A (ja) 2004-09-30
JP2004529642A5 JP2004529642A5 (https=) 2005-12-22

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ID=26961983

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JP2002580865A Withdrawn JP2004529642A (ja) 2001-04-13 2002-04-12 薬物およびプロドラッグの送達系としてのアミノ酸輸送体ａｔｂ０，＋の利用

Country Status (5)

Country Link
US (1) US20040142317A1 (https=)
EP (1) EP1384081A2 (https=)
JP (1) JP2004529642A (https=)
CA (1) CA2443732A1 (https=)
WO (1) WO2002083060A2 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPWO2021132691A1 (https=) * 2019-12-27 2021-07-01

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003271173A1 (en) * 2002-10-11 2004-05-04 Chugai Seiyaku Kabushiki Kaisha Cell growth regulator
US20090123388A1 (en) 2005-01-14 2009-05-14 Medical College Of Georgia Research Institute Prodrugs of Short-Chain Fatty Acids and Treatment Methods
WO2010042685A2 (en) * 2008-10-08 2010-04-15 Medical College Of Georgia Research Institute, Inc. Inhibitors of the atb(0,+) transporter and uses thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPWO2021132691A1 (https=) * 2019-12-27 2021-07-01
WO2021132691A1 (ja) * 2019-12-27 2021-07-01 Kagami株式会社 Ｄ－セリン輸送調節剤及びそのスクリーニング方法、並びにｄ－セリン輸送体タンパク質のスクリーニング方法

Also Published As

Publication number Publication date
CA2443732A1 (en) 2002-10-24
WO2002083060A2 (en) 2002-10-24
EP1384081A2 (en) 2004-01-28
US20040142317A1 (en) 2004-07-22
WO2002083060A3 (en) 2003-07-10

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