CA2443732A1 - Use of amino acid transporter atb0,+ as a delivery system for drugs and prodrugs - Google Patents

Use of amino acid transporter atb0,+ as a delivery system for drugs and prodrugs Download PDF

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Publication number
CA2443732A1
CA2443732A1 CA002443732A CA2443732A CA2443732A1 CA 2443732 A1 CA2443732 A1 CA 2443732A1 CA 002443732 A CA002443732 A CA 002443732A CA 2443732 A CA2443732 A CA 2443732A CA 2443732 A1 CA2443732 A1 CA 2443732A1
Authority
CA
Canada
Prior art keywords
compound
atb
transport
phenylglycine
carnitine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002443732A
Other languages
English (en)
French (fr)
Inventor
Vadivel Ganapathy
Takahiro Hatanaka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chugai Pharmaceutical Co Ltd
Augusta University Research Institute Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2443732A1 publication Critical patent/CA2443732A1/en
Abandoned legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • General Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CA002443732A 2001-04-13 2002-04-12 Use of amino acid transporter atb0,+ as a delivery system for drugs and prodrugs Abandoned CA2443732A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US28332601P 2001-04-13 2001-04-13
US60/283,326 2001-04-13
US30616801P 2001-07-19 2001-07-19
US60/306,168 2001-07-19
PCT/JP2002/003678 WO2002083060A2 (en) 2001-04-13 2002-04-12 Use of amino acid transporter atb0,+ as a delivery system for drugs and prodrugs

Publications (1)

Publication Number Publication Date
CA2443732A1 true CA2443732A1 (en) 2002-10-24

Family

ID=26961983

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002443732A Abandoned CA2443732A1 (en) 2001-04-13 2002-04-12 Use of amino acid transporter atb0,+ as a delivery system for drugs and prodrugs

Country Status (5)

Country Link
US (1) US20040142317A1 (https=)
EP (1) EP1384081A2 (https=)
JP (1) JP2004529642A (https=)
CA (1) CA2443732A1 (https=)
WO (1) WO2002083060A2 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003271173A1 (en) * 2002-10-11 2004-05-04 Chugai Seiyaku Kabushiki Kaisha Cell growth regulator
US20090123388A1 (en) 2005-01-14 2009-05-14 Medical College Of Georgia Research Institute Prodrugs of Short-Chain Fatty Acids and Treatment Methods
WO2010042685A2 (en) * 2008-10-08 2010-04-15 Medical College Of Georgia Research Institute, Inc. Inhibitors of the atb(0,+) transporter and uses thereof
US20230220387A1 (en) * 2019-12-27 2023-07-13 Kagami Inc. D-serine transport modifier and screening method thereof, and screening method of d-serine transporter protein

Also Published As

Publication number Publication date
WO2002083060A2 (en) 2002-10-24
EP1384081A2 (en) 2004-01-28
US20040142317A1 (en) 2004-07-22
JP2004529642A (ja) 2004-09-30
WO2002083060A3 (en) 2003-07-10

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued