JP2004525952A - Ｍｒｐ１を阻害するための化合物および医薬組成物 - Google Patents

Ｍｒｐ１を阻害するための化合物および医薬組成物 Download PDF

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Publication number
JP2004525952A
JP2004525952A JP2002579468A JP2002579468A JP2004525952A JP 2004525952 A JP2004525952 A JP 2004525952A JP 2002579468 A JP2002579468 A JP 2002579468A JP 2002579468 A JP2002579468 A JP 2002579468A JP 2004525952 A JP2004525952 A JP 2004525952A
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Japan
Prior art keywords
optionally substituted
alkyl
heterocycle
mmol
phenyl
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Pending
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JP2002579468A
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Japanese (ja)
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JP2004525952A5 (enExample
Inventor
ジェフリー・ダニエル・コーエン
ルイス・ニコラウス・ジュンガイム
ブライアン・スティーブン・ミュール
ケネス・ジェフ・スラッシャー
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Eli Lilly and Co
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Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of JP2004525952A publication Critical patent/JP2004525952A/ja
Publication of JP2004525952A5 publication Critical patent/JP2004525952A5/ja
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2002579468A 2001-04-09 2002-03-27 Ｍｒｐ１を阻害するための化合物および医薬組成物 Pending JP2004525952A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28264201P 2001-04-09 2001-04-09
PCT/US2002/006662 WO2002081480A1 (en) 2001-04-09 2002-03-27 Compounds and pharmaceutical compositions for inhibiting mrp1

Publications (2)

Publication Number Publication Date
JP2004525952A true JP2004525952A (ja) 2004-08-26
JP2004525952A5 JP2004525952A5 (enExample) 2005-12-22

Family

ID=23082449

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2002579468A Pending JP2004525952A (ja) 2001-04-09 2002-03-27 Ｍｒｐ１を阻害するための化合物および医薬組成物

Country Status (5)

Country Link
US (1) US7101891B2 (enExample)
EP (1) EP1392701A1 (enExample)
JP (1) JP2004525952A (enExample)
CA (1) CA2442141A1 (enExample)
WO (1) WO2002081480A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JO2409B1 (en) 2000-11-21 2007-06-17 شركة جانسين فارماسوتيكا ان. في Second-phenyl carboxy amides are useful as lipid-lowering agents
JP2009508963A (ja) * 2005-09-21 2009-03-05 インサイト・コーポレイション アミド化合物および医薬組成物としてのその使用
WO2007101270A1 (en) * 2006-03-02 2007-09-07 Incyte Corporation MODULATORS OF 11-β HYDROXYL STEROID DEHYDROGENASE TYPE 1, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6369070B1 (en) * 1998-04-08 2002-04-09 Eli Lilly And Company Methods for inhibiting mrp1
US6743794B2 (en) * 1999-12-22 2004-06-01 Eli Lilly And Company Methods and compounds for inhibiting MRP1

Also Published As

Publication number Publication date
US7101891B2 (en) 2006-09-05
WO2002081480A1 (en) 2002-10-17
EP1392701A1 (en) 2004-03-03
CA2442141A1 (en) 2002-10-17
US20040116460A1 (en) 2004-06-17

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