JP2004511779A - 検体検出システム - Google Patents
検体検出システム Download PDFInfo
- Publication number
- JP2004511779A JP2004511779A JP2002534838A JP2002534838A JP2004511779A JP 2004511779 A JP2004511779 A JP 2004511779A JP 2002534838 A JP2002534838 A JP 2002534838A JP 2002534838 A JP2002534838 A JP 2002534838A JP 2004511779 A JP2004511779 A JP 2004511779A
- Authority
- JP
- Japan
- Prior art keywords
- sensor
- semiconductor element
- analyte
- binder layer
- conductive element
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000001514 detection method Methods 0.000 title claims description 139
- 239000012491 analyte Substances 0.000 claims abstract description 96
- 229920000642 polymer Polymers 0.000 claims abstract description 15
- 239000004065 semiconductor Substances 0.000 claims description 106
- 239000011230 binding agent Substances 0.000 claims description 101
- 239000000126 substance Substances 0.000 claims description 45
- 238000000034 method Methods 0.000 claims description 35
- 239000000463 material Substances 0.000 claims description 20
- 230000003287 optical effect Effects 0.000 claims description 9
- 150000002894 organic compounds Chemical class 0.000 claims description 8
- 238000005401 electroluminescence Methods 0.000 claims description 6
- 238000002161 passivation Methods 0.000 claims description 2
- WABPQHHGFIMREM-UHFFFAOYSA-N lead(0) Chemical compound [Pb] WABPQHHGFIMREM-UHFFFAOYSA-N 0.000 claims 1
- 238000006243 chemical reaction Methods 0.000 abstract description 27
- 229920001059 synthetic polymer Polymers 0.000 abstract description 3
- 229920005615 natural polymer Polymers 0.000 abstract 1
- 239000010410 layer Substances 0.000 description 87
- 230000006870 function Effects 0.000 description 40
- 239000000523 sample Substances 0.000 description 32
- 108090000790 Enzymes Proteins 0.000 description 31
- 102000004190 Enzymes Human genes 0.000 description 31
- 229940088598 enzyme Drugs 0.000 description 31
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 16
- 229910052782 aluminium Inorganic materials 0.000 description 15
- 239000011888 foil Substances 0.000 description 15
- 238000000576 coating method Methods 0.000 description 13
- 239000000427 antigen Substances 0.000 description 12
- 108091007433 antigens Proteins 0.000 description 12
- 102000036639 antigens Human genes 0.000 description 12
- 238000010586 diagram Methods 0.000 description 12
- 229910052751 metal Inorganic materials 0.000 description 12
- 239000002184 metal Substances 0.000 description 12
- 108020004707 nucleic acids Proteins 0.000 description 12
- 102000039446 nucleic acids Human genes 0.000 description 12
- 150000007523 nucleic acids Chemical class 0.000 description 12
- 229910052737 gold Inorganic materials 0.000 description 11
- 239000010931 gold Substances 0.000 description 11
- 230000008859 change Effects 0.000 description 10
- 239000011248 coating agent Substances 0.000 description 10
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 10
- AMGQUBHHOARCQH-UHFFFAOYSA-N indium;oxotin Chemical compound [In].[Sn]=O AMGQUBHHOARCQH-UHFFFAOYSA-N 0.000 description 10
- 102000005962 receptors Human genes 0.000 description 10
- 108020003175 receptors Proteins 0.000 description 10
- 238000005259 measurement Methods 0.000 description 9
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 8
- -1 antibodies Proteins 0.000 description 8
- 229920002521 macromolecule Polymers 0.000 description 8
- 241000234295 Musa Species 0.000 description 7
- 235000018290 Musa x paradisiaca Nutrition 0.000 description 7
- 239000008280 blood Substances 0.000 description 7
- 210000004369 blood Anatomy 0.000 description 7
- 230000003197 catalytic effect Effects 0.000 description 7
- 102000004169 proteins and genes Human genes 0.000 description 7
- 108090000623 proteins and genes Proteins 0.000 description 7
- 238000002474 experimental method Methods 0.000 description 6
- 235000013305 food Nutrition 0.000 description 6
- 238000012545 processing Methods 0.000 description 6
- 230000004044 response Effects 0.000 description 6
- 108020004414 DNA Proteins 0.000 description 5
- 241001646719 Escherichia coli O157:H7 Species 0.000 description 5
- 241000935974 Paralichthys dentatus Species 0.000 description 5
- 230000001580 bacterial effect Effects 0.000 description 5
- 239000003446 ligand Substances 0.000 description 5
- 230000001717 pathogenic effect Effects 0.000 description 5
- 102000004196 processed proteins & peptides Human genes 0.000 description 5
- 108090000765 processed proteins & peptides Proteins 0.000 description 5
- 239000000243 solution Substances 0.000 description 5
- 239000000758 substrate Substances 0.000 description 5
- 238000012546 transfer Methods 0.000 description 5
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 4
- 238000004090 dissolution Methods 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- 239000008103 glucose Substances 0.000 description 4
- 229910001385 heavy metal Inorganic materials 0.000 description 4
- 239000000976 ink Substances 0.000 description 4
- 238000012544 monitoring process Methods 0.000 description 4
- 244000052769 pathogen Species 0.000 description 4
- 238000011002 quantification Methods 0.000 description 4
- 150000003839 salts Chemical class 0.000 description 4
- 239000013545 self-assembled monolayer Substances 0.000 description 4
- 230000035945 sensitivity Effects 0.000 description 4
- 239000011780 sodium chloride Substances 0.000 description 4
- 239000007787 solid Substances 0.000 description 4
- 241000894007 species Species 0.000 description 4
- 238000012360 testing method Methods 0.000 description 4
- 241000894006 Bacteria Species 0.000 description 3
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 3
- 229930006000 Sucrose Natural products 0.000 description 3
- 241000700605 Viruses Species 0.000 description 3
- 244000052616 bacterial pathogen Species 0.000 description 3
- 230000008901 benefit Effects 0.000 description 3
- 230000000295 complement effect Effects 0.000 description 3
- 238000013461 design Methods 0.000 description 3
- 235000014113 dietary fatty acids Nutrition 0.000 description 3
- 230000005684 electric field Effects 0.000 description 3
- 229930195729 fatty acid Natural products 0.000 description 3
- 239000000194 fatty acid Substances 0.000 description 3
- 150000004665 fatty acids Chemical class 0.000 description 3
- 239000007789 gas Substances 0.000 description 3
- 230000007774 longterm Effects 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 229920000620 organic polymer Polymers 0.000 description 3
- 238000007747 plating Methods 0.000 description 3
- 230000027756 respiratory electron transport chain Effects 0.000 description 3
- 239000005720 sucrose Substances 0.000 description 3
- 239000000725 suspension Substances 0.000 description 3
- 239000002966 varnish Substances 0.000 description 3
- 230000003612 virological effect Effects 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- 102000053602 DNA Human genes 0.000 description 2
- 238000002965 ELISA Methods 0.000 description 2
- SXRSQZLOMIGNAQ-UHFFFAOYSA-N Glutaraldehyde Chemical compound O=CCCCC=O SXRSQZLOMIGNAQ-UHFFFAOYSA-N 0.000 description 2
- 238000004082 amperometric method Methods 0.000 description 2
- 238000004458 analytical method Methods 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 210000001124 body fluid Anatomy 0.000 description 2
- 239000010839 body fluid Substances 0.000 description 2
- 206010012601 diabetes mellitus Diseases 0.000 description 2
- DOIRQSBPFJWKBE-UHFFFAOYSA-N dibutyl phthalate Chemical compound CCCCOC(=O)C1=CC=CC=C1C(=O)OCCCC DOIRQSBPFJWKBE-UHFFFAOYSA-N 0.000 description 2
- 238000007598 dipping method Methods 0.000 description 2
- 230000005611 electricity Effects 0.000 description 2
- 230000005686 electrostatic field Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 238000006911 enzymatic reaction Methods 0.000 description 2
- 230000005669 field effect Effects 0.000 description 2
- 210000001156 gastric mucosa Anatomy 0.000 description 2
- 230000005525 hole transport Effects 0.000 description 2
- 150000002500 ions Chemical class 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- TWNQGVIAIRXVLR-UHFFFAOYSA-N oxo(oxoalumanyloxy)alumane Chemical compound O=[Al]O[Al]=O TWNQGVIAIRXVLR-UHFFFAOYSA-N 0.000 description 2
- 229920005596 polymer binder Polymers 0.000 description 2
- 239000002491 polymer binding agent Substances 0.000 description 2
- 239000002094 self assembled monolayer Substances 0.000 description 2
- 239000002356 single layer Substances 0.000 description 2
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- 239000004971 Cross linker Substances 0.000 description 1
- 108010069941 DNA receptor Proteins 0.000 description 1
- 241000588724 Escherichia coli Species 0.000 description 1
- 108010015776 Glucose oxidase Proteins 0.000 description 1
- 239000004366 Glucose oxidase Substances 0.000 description 1
- 241000589989 Helicobacter Species 0.000 description 1
- 241000590002 Helicobacter pylori Species 0.000 description 1
- 239000000020 Nitrocellulose Substances 0.000 description 1
- 108090000854 Oxidoreductases Proteins 0.000 description 1
- 102000004316 Oxidoreductases Human genes 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 description 1
- 108010046334 Urease Proteins 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 239000012790 adhesive layer Substances 0.000 description 1
- 239000000443 aerosol Substances 0.000 description 1
- 229940035674 anesthetics Drugs 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 239000007900 aqueous suspension Substances 0.000 description 1
- 238000003491 array Methods 0.000 description 1
- 238000004630 atomic force microscopy Methods 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 150000001732 carboxylic acid derivatives Chemical class 0.000 description 1
- 238000006555 catalytic reaction Methods 0.000 description 1
- 239000002738 chelating agent Substances 0.000 description 1
- 230000009920 chelation Effects 0.000 description 1
- 238000010382 chemical cross-linking Methods 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 230000001149 cognitive effect Effects 0.000 description 1
- 230000001332 colony forming effect Effects 0.000 description 1
- 239000002131 composite material Substances 0.000 description 1
- 229920001940 conductive polymer Polymers 0.000 description 1
- 230000008878 coupling Effects 0.000 description 1
- 238000010168 coupling process Methods 0.000 description 1
- 238000005859 coupling reaction Methods 0.000 description 1
- 238000004132 cross linking Methods 0.000 description 1
- 239000003431 cross linking reagent Substances 0.000 description 1
- 238000013500 data storage Methods 0.000 description 1
- 230000008021 deposition Effects 0.000 description 1
- 229910003460 diamond Inorganic materials 0.000 description 1
- 239000010432 diamond Substances 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000000428 dust Substances 0.000 description 1
- 238000001839 endoscopy Methods 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 239000002532 enzyme inhibitor Substances 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 230000004907 flux Effects 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 239000003193 general anesthetic agent Substances 0.000 description 1
- 230000007274 generation of a signal involved in cell-cell signaling Effects 0.000 description 1
- 230000002068 genetic effect Effects 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 229940116332 glucose oxidase Drugs 0.000 description 1
- 235000019420 glucose oxidase Nutrition 0.000 description 1
- 150000002343 gold Chemical class 0.000 description 1
- 231100001261 hazardous Toxicity 0.000 description 1
- 229940037467 helicobacter pylori Drugs 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 230000028993 immune response Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 239000003112 inhibitor Substances 0.000 description 1
- 150000002484 inorganic compounds Chemical class 0.000 description 1
- 229910010272 inorganic material Inorganic materials 0.000 description 1
- 239000002207 metabolite Substances 0.000 description 1
- 150000002739 metals Chemical class 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 210000000653 nervous system Anatomy 0.000 description 1
- 229920001220 nitrocellulos Polymers 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- 230000001590 oxidative effect Effects 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- XNGIFLGASWRNHJ-UHFFFAOYSA-L phthalate(2-) Chemical compound [O-]C(=O)C1=CC=CC=C1C([O-])=O XNGIFLGASWRNHJ-UHFFFAOYSA-L 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 238000004886 process control Methods 0.000 description 1
- 230000000644 propagated effect Effects 0.000 description 1
- 230000002285 radioactive effect Effects 0.000 description 1
- 230000009257 reactivity Effects 0.000 description 1
- 238000004574 scanning tunneling microscopy Methods 0.000 description 1
- 238000013207 serial dilution Methods 0.000 description 1
- 238000002791 soaking Methods 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 230000006641 stabilisation Effects 0.000 description 1
- 238000011105 stabilization Methods 0.000 description 1
- 150000003431 steroids Chemical class 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 235000000346 sugar Nutrition 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 239000010409 thin film Substances 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 230000032258 transport Effects 0.000 description 1
- 229920003169 water-soluble polymer Polymers 0.000 description 1
Images
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
- G01N33/5438—Electrodes
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- General Physics & Mathematics (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Food Science & Technology (AREA)
- Pathology (AREA)
- Nanotechnology (AREA)
- Condensed Matter Physics & Semiconductors (AREA)
- Materials Engineering (AREA)
- Crystallography & Structural Chemistry (AREA)
- Composite Materials (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IL13896200 | 2000-10-12 | ||
| PCT/US2001/029791 WO2002031504A1 (en) | 2000-10-12 | 2001-09-25 | An analyte detection system |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004511779A true JP2004511779A (ja) | 2004-04-15 |
| JP2004511779A5 JP2004511779A5 (enrdf_load_stackoverflow) | 2005-04-14 |
Family
ID=11074727
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002534838A Pending JP2004511779A (ja) | 2000-10-12 | 2001-09-25 | 検体検出システム |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP1325330A4 (enrdf_load_stackoverflow) |
| JP (1) | JP2004511779A (enrdf_load_stackoverflow) |
| AU (1) | AU2001294656A1 (enrdf_load_stackoverflow) |
| WO (1) | WO2002031504A1 (enrdf_load_stackoverflow) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10319155B4 (de) | 2003-04-29 | 2008-02-14 | Bruker Daltonik Gmbh | Elektrisch auslesbare Bindungen von Analytmolekülen an immobilisierten Sondenmolekülen |
| CN109406617B (zh) * | 2018-10-23 | 2022-06-24 | 太原科技大学 | 一种基于电磁效应的病菌检测装置及其检测方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0721478B2 (ja) * | 1986-03-31 | 1995-03-08 | 財団法人化学及血清療法研究所 | 免疫センサ−用作用膜 |
| JP2578370B2 (ja) * | 1989-07-24 | 1997-02-05 | アンリツ株式会社 | 味覚センサ及びその製造方法 |
| IL93020A (en) * | 1990-01-09 | 1995-06-29 | Yeda Res & Dev | Biosensors comprising a lipid bilayer doped with ion channels anchored to a recording electrode by bridging molecules |
| WO1999066322A1 (en) * | 1998-06-15 | 1999-12-23 | Biosensor Systems Design, Inc. (1998) | A sensor for analyte detection |
| IL124903A0 (en) * | 1998-06-15 | 1999-01-26 | Bauer Alan Josef | An enzyme biosensor |
| WO2000077522A1 (en) * | 1999-06-15 | 2000-12-21 | Biosensor Systems Design, Inc. | Analytic sensor apparatus and method |
-
2001
- 2001-09-25 WO PCT/US2001/029791 patent/WO2002031504A1/en not_active Application Discontinuation
- 2001-09-25 EP EP01975319A patent/EP1325330A4/en not_active Withdrawn
- 2001-09-25 AU AU2001294656A patent/AU2001294656A1/en not_active Abandoned
- 2001-09-25 JP JP2002534838A patent/JP2004511779A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP1325330A4 (en) | 2004-12-08 |
| AU2001294656A1 (en) | 2002-04-22 |
| EP1325330A1 (en) | 2003-07-09 |
| WO2002031504A1 (en) | 2002-04-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US20040197821A1 (en) | Rapid-detection biosensor | |
| Curulli | Electrochemical biosensors in food safety: Challenges and perspectives | |
| Pastucha et al. | Magnetic nanoparticles for smart electrochemical immunoassays: a review on recent developments | |
| US6322963B1 (en) | Sensor for analyte detection | |
| US6503701B1 (en) | Analytic sensor apparatus and method | |
| Zhang et al. | Multiplexed sandwich immunoassays using flow-injection electrochemiluminescence with designed substrate spatial-resolved technique for detection of tumor markers | |
| US6096497A (en) | Electrostatic enzyme biosensor | |
| US20100231242A1 (en) | Electronic sensing of biological and chemical agents using functionalized nanostructures | |
| CN101231287B (zh) | 外场诱导电极中排列纳米颗粒制备生物传感器的方法 | |
| EP1185868A1 (en) | Analytic sensor apparatus and method | |
| Cheng et al. | Integrated electrochemical lateral flow immunoassays (eLFIAs): recent advances | |
| Kothiyal et al. | Field effect transistor (FET)-sensor for biological applications | |
| Qazi et al. | Recent advancement for enhanced e. Coli detection in electrochemical biosensors | |
| CN112924662A (zh) | 一种电致化学发光免疫传感器的制备方法及其在检测黄曲霉毒素b1中的应用 | |
| US20200149094A1 (en) | Methods for increasing the molecular specificity of a nanosensor | |
| Carvalho et al. | Electro sensors based on quantum dots and their applications in diagnostic medicine | |
| CN110441535A (zh) | 一种基于Pd NCs功能化CuInOS检测降钙素原的电化学免疫传感器的制备方法 | |
| Rodrigues et al. | On the detection of cTnI-a comparison of surface-plasmon optical-electrochemical-, and electronic sensing concepts | |
| US20040037746A1 (en) | Analyte detection system | |
| JP2004511779A (ja) | 検体検出システム | |
| Byon et al. | Label-free biomolecular detection using carbon nanotube field effect transistors | |
| Lee et al. | Electrical detection-based analytic biodevice technology | |
| Maity et al. | Electrochemical sensors: Core principle, new fabrication trends, and their applications | |
| WO1999066322A1 (en) | A sensor for analyte detection | |
| Sun et al. | Chemical Sensors using Single‐Molecule Electrical Measurements |