JP2004510162A5 - - Google Patents
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- Publication number
- JP2004510162A5 JP2004510162A5 JP2002530645A JP2002530645A JP2004510162A5 JP 2004510162 A5 JP2004510162 A5 JP 2004510162A5 JP 2002530645 A JP2002530645 A JP 2002530645A JP 2002530645 A JP2002530645 A JP 2002530645A JP 2004510162 A5 JP2004510162 A5 JP 2004510162A5
- Authority
- JP
- Japan
- Prior art keywords
- linker
- conjugate
- biomolecule
- reagent composition
- uniform stoichiometry
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10048417A DE10048417A1 (de) | 2000-09-29 | 2000-09-29 | Verbindungen mit verzweigtem Linker |
| EP01107491A EP1245956A1 (en) | 2001-03-29 | 2001-03-29 | Conjugates of defined stoichiometry |
| PCT/EP2001/011101 WO2002027317A2 (en) | 2000-09-29 | 2001-09-26 | Conjugates of defined stoichiometry |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004510162A JP2004510162A (ja) | 2004-04-02 |
| JP2004510162A5 true JP2004510162A5 (cg-RX-API-DMAC10.html) | 2005-03-03 |
| JP3836429B2 JP3836429B2 (ja) | 2006-10-25 |
Family
ID=26007222
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002530645A Expired - Fee Related JP3836429B2 (ja) | 2000-09-29 | 2001-09-26 | 規定した化学量論の結合体 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7897404B2 (cg-RX-API-DMAC10.html) |
| EP (2) | EP1364208B1 (cg-RX-API-DMAC10.html) |
| JP (1) | JP3836429B2 (cg-RX-API-DMAC10.html) |
| AT (1) | ATE313796T1 (cg-RX-API-DMAC10.html) |
| AU (1) | AU2001289923A1 (cg-RX-API-DMAC10.html) |
| CA (1) | CA2420768C (cg-RX-API-DMAC10.html) |
| DE (1) | DE60116146T2 (cg-RX-API-DMAC10.html) |
| ES (1) | ES2254489T3 (cg-RX-API-DMAC10.html) |
| WO (1) | WO2002027317A2 (cg-RX-API-DMAC10.html) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100361933B1 (ko) | 1993-09-08 | 2003-02-14 | 라 졸라 파마슈티칼 컴파니 | 화학적으로정의된비중합성결합가플랫폼분자및그것의콘주게이트 |
| CA2414076A1 (en) | 2000-06-08 | 2001-12-13 | La Jolla Pharmaceutical Company | Multivalent platform molecules comprising high molecular weight polyethylene oxide |
| WO2012055815A1 (en) | 2010-10-25 | 2012-05-03 | Roche Diagnostics Gmbh | Use of signal enhancing compounds in electrochemiluminescence detection |
| US10131682B2 (en) | 2012-11-24 | 2018-11-20 | Hangzhou Dac Biotech Co., Ltd. | Hydrophilic linkers and their uses for conjugation of drugs to a cell binding molecules |
| AU2018342105B2 (en) | 2017-09-26 | 2023-11-16 | University Of Florida Research Foundation, Incorporated | Use of metformin and analogs thereof to reduce ran protein levels in the treatment of neurological disorders |
| US20220331442A1 (en) * | 2018-03-15 | 2022-10-20 | Levim Biotech Llp | Antibody-biomolecule conjugates linked through multifunctional macromolecule and uses thereof |
| AU2020348916B2 (en) * | 2019-09-20 | 2025-12-18 | University Of Florida Research Foundation, Incorporated | Detection of antibodies against RAN proteins from serum and tissue lysates |
| WO2021072187A2 (en) | 2019-10-10 | 2021-04-15 | University Of Florida Research Foundation, Incorporated | Ran proteins as biomarkers in cag/ctg expansion disorders |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2493382A (en) * | 1948-10-29 | 1950-01-03 | American Cyanamid Co | Automatic sample collector |
| GB2095818B (en) | 1981-03-27 | 1985-10-02 | Exxon Research Engineering Co | Staged adsorption/resorption heat pump |
| US5047324A (en) * | 1986-12-09 | 1991-09-10 | Miles Inc. | Substantially pure enzyme-antibody conjugate preparations |
| US5554748A (en) * | 1989-04-07 | 1996-09-10 | Nycomed Salutar, Inc. | Adducts of macrocyclic chelants |
| CA2087163A1 (en) * | 1990-07-20 | 1992-01-21 | Hubert Agback | Heterobifunctional reagents and conjugates with oxaalkylene units for amphiphilic bridge structures |
| US6120768A (en) * | 1993-05-17 | 2000-09-19 | Immunomedics, Inc. | Dota-biotin derivatives |
| US5804371A (en) | 1994-07-25 | 1998-09-08 | Boehringer Mannheim Gmbh | Hapten-labelled peptides |
| DE59507438D1 (de) * | 1994-07-25 | 2000-01-20 | Roche Diagnostics Gmbh | Hydrophile metallkomplexe |
| ES2148540T3 (es) * | 1994-07-25 | 2000-10-16 | Roche Diagnostics Gmbh | Complejos metalicos con enlazador cargado. |
| WO1996003652A1 (de) | 1994-07-25 | 1996-02-08 | Boehringer Mannheim Gmbh | Bestimmung von spezifischem immunglobulin unter verwendung multipler antigene |
| WO1996003651A1 (de) | 1994-07-25 | 1996-02-08 | Boehringer Mannheim Gmbh | Metallchelat-markierte peptide |
| DE4430972A1 (de) * | 1994-07-25 | 1996-02-01 | Boehringer Mannheim Gmbh | Bestimmung von spezifischem Immunglobulin unter Verwendung multipler Antigene |
| GB9415143D0 (en) | 1994-07-27 | 1994-09-14 | Edwards Raymond | Glycated haemoglobin assay |
| AU3649697A (en) * | 1996-06-27 | 1998-01-14 | G.D. Searle & Co. | Particles comprising amphiphilic copolymers, having a cross-linked shell domain and an interior core domain, useful for pharmaceutical and other applications |
-
2001
- 2001-08-26 US US10/381,941 patent/US7897404B2/en not_active Expired - Fee Related
- 2001-09-26 EP EP01969773A patent/EP1364208B1/en not_active Expired - Lifetime
- 2001-09-26 JP JP2002530645A patent/JP3836429B2/ja not_active Expired - Fee Related
- 2001-09-26 EP EP05023387A patent/EP1625857A3/en not_active Ceased
- 2001-09-26 CA CA2420768A patent/CA2420768C/en not_active Expired - Fee Related
- 2001-09-26 WO PCT/EP2001/011101 patent/WO2002027317A2/en not_active Ceased
- 2001-09-26 AT AT01969773T patent/ATE313796T1/de active
- 2001-09-26 ES ES01969773T patent/ES2254489T3/es not_active Expired - Lifetime
- 2001-09-26 AU AU2001289923A patent/AU2001289923A1/en not_active Abandoned
- 2001-09-26 DE DE60116146T patent/DE60116146T2/de not_active Expired - Lifetime
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