JP2004188111A - System and method for cleaning and sterilizing clean room - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a system and a method for cleaning and sterilizing the piping for spraying sterilizing and rinsing waters in clean rooms. <P>SOLUTION: Systems 10 and 30, for cleaning and sterilizing clean rooms, are provided with piping 11 and 31 for supplying a sterilizing water and a rinsing water to the clean rooms and a plurality of nozzles 21 and 41 installed at prescribed positions on the piping, for spraying the sterilizing water and the rinsing water in the clean rooms. At least part of the piping has double structure, consisting of an inner pipe and an outer pipe surrounding at least part of the inner pipe in the peripheral direction, so that steam can be passed through the space between the inner pipe and the outer pipe and the inside of the inner pipe and at least the outer surface of the outer pipe can be heated and sterilized thereby. <P>COPYRIGHT: (C)2004,JPO&NCIPI

Description

[0001]
[Industrial applications]
BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a cleaning sterilization system and method for cleaning and sterilizing a clean room, and more particularly, for example, cleaning or spraying or spraying a cleaning liquid into a clean room where liquid beverage production or filling and packaging processing is performed. The present invention relates to a system for sterilization and such a washing and sterilization method, and further relates to a structure and a method for residual liquid prevention and sterilization of piping of such a system.
[0002]
[Prior art]
In recent years, various bottled beverages such as mineral water, tea, and coffee have been manufactured. When filling these beverages, hot pack filling is often used for sterilization, but recently, filling has been sterilized with a filter and then filled at room temperature in a clean room. By filling the contents into a PET bottle in a clean room and capping the contents without heating, there is an advantage that deterioration of contents, change in flavor due to heating, and heating cost can be reduced by heating. However, since it is necessary to install a filling machine having a complicated structure and a device for attaching a cap (hereinafter referred to as a capper) in a clean room, it is necessary to periodically perform cleaning and sterilization in order to prevent microbial contamination of these devices. Conventionally, this operation has been performed by manually spraying a cleaning liquid and a germicidal liquid onto the apparatus by a human, and then cleaning the apparatus with sterilized water (rinse liquid). Therefore, there are problems in terms of worker health, work efficiency and reproducibility. In order to solve these problems, etc., automation of cleaning and sterilization in a clean room in a beverage filling system has been attempted, but there has been no success as an automatic cleaning and sterilization system using a cleaning agent and a sterilizing agent. .
[0003]
One of the biggest reasons why it is difficult to automate cleanroom cleaning and sterilization is that sterile air always flows from top to bottom in the cleanroom. Alternatively, there is a problem in that bacteria adhere to and proliferate to the outside, and when the bacteria fall, they jump into a tank or a bottle of a beverage below and become contaminated. In particular, the outer periphery of the uppermost pipe (hereinafter referred to as the outer periphery) can be temporarily sterilized by spraying a chemical solution from below, but cannot prevent the propagation of microorganisms until the next spraying of the chemical. Therefore, there has been a demand for the development of a method for preventing microbial contamination of the outer peripheral portion of a pipe.
[0004]
As a solution, a method of filling the inside of the pipe with a chemical solution and keeping it in a sterilized state can be considered, but in this case, the dropping of the liquid (so-called dripping) may contaminate the filling and damage the pipe, There have been problems such as the fact that sediment adheres to the pipe, cleaning efficiency is deteriorated, and bacteria easily proliferate in a portion where rinse water is accumulated. Also in this case, although the inside of the tube can be sterilized or sterilized, the outer peripheral surface of the tube to which bacteria have adhered cannot be sterilized or sterilized. Therefore, development of a method of sterilizing the outer peripheral surface of the upper pipe has been required.
[0005]
Also, it is difficult to sterilize the nozzle tip portion of the upper pipe, and there is a risk that microorganisms proliferate in that portion after spraying sterilizing water for rinsing, and the contaminated liquid falls and enters the PET bottle or tank. Therefore, development of a method of sterilizing a nozzle of a pipe in a clean room was also required. In addition, by developing a method capable of sterilizing the peripheral portion of the piping, it is expected that sterilization and cleaning can be automated or semi-automated, and development of an automatic system for cleaning and sterilizing work in a clean room has been desired.
[0006]
[Problems to be solved by the invention]
The present invention has been made based on such a demand, and an object of the present invention is to provide a method and system for cleaning and sterilizing a clean room.
Another object of the present invention is to disinfect the clean room, at least a part of the pipe for spraying the cleaning liquid has a double structure, sterilization, after spraying the cleaning liquid, passing the pipe between the inner pipe and the outside through the steam. It is an object of the present invention to provide a method and system for cleaning and sterilizing, which prevents the residual moisture and bacteria by heating and sterilizing.
Another object of the present invention is to provide a residual liquid prevention and sterilization structure for pipes that performs sterilization by removing residual liquid adhering to the inside and outside of pipes in a clean room cleaning and sterilizing system.
It is still another object of the present invention to provide a method for disinfecting and injecting a cleaning liquid into a clean room through a pipe and a plurality of nozzles attached to the pipe, with the difference in foaming efficiency being reduced and foaming.
[0007]
[Means for Solving the Problems]
According to the first aspect of the present invention, in a clean room cleaning / sterilizing system, a pipe for supplying sterilization, a cleaning liquid and a rinsing liquid into the clean room, and a pipe attached to a predetermined position of the pipe, and sterilizing, cleaning liquid and And at least one nozzle for injecting a rinsing liquid, wherein at least a part of the pipes has a double structure having an inner pipe and an outer pipe surrounding at least a part of a circumferential direction of the inner pipe, A washing and sterilizing system is provided, wherein steam can be passed between the inner tube and the outer tube to heat and sterilize the inside of the inner tube and at least the outer periphery of the outer tube.
According to this cleaning / sterilizing system, cleaning and sterilization of the clean room are performed, and the remaining of water and the propagation of bacteria inside and outside the pipes in the clean room can be prevented. In the above system, the pipes may be arranged in a plurality of stages at different heights in the vertical direction, and at least the uppermost pipe may have the double structure. Further, by disposing a nozzle attached to the pipe as close to the pipe as possible, the heat of the pipe may be transmitted to the nozzle to increase the temperature of the nozzle and keep the nozzle in a dry state. Further, the pipe may be of a sanitary specification.
[0008]
According to the invention as set forth in claim 5, in the method for cleaning and sterilizing a clean room, a pipe for supplying sterilization, a cleaning liquid and a rinsing liquid into the clean room, wherein at least a part of the pipe is an inner pipe and a circumferential direction of the inner pipe. A pipe having a double structure having an outer pipe surrounding at least a part of the pipe, and at least one nozzle which is attached to a predetermined position of the pipe and injects a sterilizing liquid, a cleaning liquid and a rinsing liquid into the clean room. Then, the sterilization, cleaning solution, rinsing solution and sterile gas are injected in the clean room through the pipe and the nozzle at a time interval in order, and thereafter, steam is passed between the inner pipe and the outer pipe. A cleaning and sterilizing method is provided, wherein drying and sterilizing the inside of the inner tube and at least drying and sterilizing the outer periphery of the outer tube.
According to this cleaning and sterilizing method, the clean room is cleaned and sterilized, and the remaining moisture and the propagation of bacteria inside and outside the pipes in the clean room can be prevented.
In the cleaning / sterilizing method, when sterilizing and injecting the cleaning liquid into the clean room, a sterile gas may be added to the sterilizing / cleaning liquid to foam the liquid, and the liquid may be injected. Also, a difference in the bubbling efficiency from the nozzle in the area may be reduced by introducing aseptic gas into the pipe from both sides of the area where the nozzle is installed.
Further, in the cleaning sterilization method, sterilization into the pipe, prior to the supply of the cleaning liquid, sterilization by flowing steam between the inner pipe and the outer pipe of the double-structured pipe, so as to dry. In this case, the cooling may be performed by flowing steam between the inner pipe and the outer pipe of the double-structured pipe and then flowing a cooling gas. Furthermore, by disposing the nozzle attached to the pipe as close to the pipe as possible, the heat of the pipe may be transmitted to the nozzle, thereby increasing the temperature of the nozzle and keeping the nozzle in a dry state.
[0009]
In the invention according to claim 11, in a residual liquid prevention and sterilization structure of a pipe for performing sterilization by eliminating residual liquid adhering to the inside and outside of a pipe in a clean room cleaning and sterilizing system, the pipe for which residual liquid is to be prevented and sterilized is provided. Has a double structure having an inner tube and an outer tube surrounding at least a part of the inner tube in a circumferential direction, wherein the inside of the inner tube passes steam between the inner tube and the outer tube, and at least an outer periphery of the outer tube. The present invention provides a structure for preventing residual liquid and disinfection of piping, characterized in that it can be dried and sterilized.
In the method for preventing and sterilizing residual liquid in the above-mentioned pipe, sterilization, washing liquid and rinsing liquid are supplied to the inner pipe at different times, and then sterile gas is introduced into the inner pipe to discharge the residual liquid in the inner pipe. Thereafter, steam may be sent between the inner tube and the outer tube.
In the method according to the thirteenth aspect, in the method of disinfecting a clean room and bubbling and spraying a cleaning liquid through a pipe and at least one nozzle attached to the pipe, air is introduced from both sides of a nozzle installation area of the pipe. By doing so, there is provided a method for spraying a sterilizing and cleaning liquid, characterized in that the difference in the bubbling efficiency from the nozzle during that time is reduced.
[0010]
【Example】
Hereinafter, embodiments of the present invention will be described with reference to the drawings as a cleaning and sterilizing system for a clean room (hereinafter, referred to as CR) for a liquid beverage filling facility.
1 to 3 show three CR1 to CR3 for a beverage filling facility, which are separated from the outside by a peripheral wall 6 and also from each other by a partition 7 in a known manner. A rinser 1 for washing and rinsing the container is arranged in CR1, a beverage filling device 3 for filling a beverage in the container washed with the rinser is arranged in CR2, and a lid is attached to the container in CR3. Although the present invention is not a invention of a rinser, a beverage filling device, and a capper, the description of their structures and operations will be omitted. Further, since the basic structure of the cleaning and sterilizing system for CR is the same for each CR, the cleaning and sterilizing systems for CR1 and CR2 will be described below.
[0011]
In FIG. 1 to FIG. 4, the cleaning / sterilizing system 10 for CR1 includes upper, middle, and lower pipes 11, 12 for spraying or spraying a cleaning liquid and a sterilizing liquid at positions vertically separated in the CR1. And 13 are provided. FIG. 1 shows a plan view of upper pipes 11 and 31 and nozzles 21 and 41 attached thereto.
FIG. 2 shows the planar arrangement of the middle pipes 12 and 32 and the nozzles 22 and 42 attached thereto, and FIG. 3 shows the planar arrangement of the lower pipes 13 and 33 and the nozzles 23 and 43 attached thereto. The planar arrangement position of the upper pipe 11 is as shown in FIG. 1, and a nozzle 21 for spraying or spraying a cleaning liquid, a sterilizing liquid or the like is attached to the tip and / or the middle of the pipe 11. The arrangement is as shown in FIGS. Further, the planar arrangement position of the middle pipe 12 is as shown in FIG. 2, and a nozzle 22 for spraying or spraying a cleaning liquid, a sterilizing liquid or the like is attached to the tip and / or the middle of the pipe 12, The arrangement of the nozzles is as shown in FIGS. Further, a planar arrangement position of the lower pipe 13 is as shown in FIG. 3, and a nozzle 23 for spraying or spraying a cleaning liquid, a sterilizing liquid, or the like is attached to the tip and / or the middle of the pipe 13, The arrangement of the nozzles is as shown in FIGS.
[0012]
In FIGS. 1 to 3 and 5, the cleaning / sterilizing system 30 for CR2 includes upper, middle and lower pipes for spraying or spraying the cleaning liquid and the sterilizing liquid at positions vertically separated in the CR2. 31, 32 and 33 are provided. The planar arrangement position of the upper pipe 31 is as shown in FIG. 1, and a nozzle 41 for spraying or spraying a cleaning liquid, a sterilizing liquid or the like is attached to the tip and / or the middle of the pipe 31. The arrangement is as shown in FIGS. Further, the planar arrangement position of the middle pipe 32 is as shown in FIG. 2, and a nozzle 42 for spraying or spraying a cleaning liquid, a sterilizing liquid, or the like is attached at the tip and / or the middle of the pipe 32, The arrangement of the nozzles is as shown in FIGS. Further, the planar arrangement position of the lower pipe 33 is as shown in FIG. 3, and a nozzle 43 for spraying or spraying a cleaning liquid, a sterilizing liquid, or the like is attached to the tip and / or the middle of the pipe 33, The arrangement of the nozzles is as shown in FIGS.
[0013]
In FIG. 1, among the pipes 11 to 13 and 31 to 33, in the present embodiment shown in the present example, the pipes of the upper pipes 11 and 31, the portions located in CR1 and CR2 are shown in FIGS. Although it has a double pipe structure illustrated in FIG. 7, all the other pipes have a single structure. The double structure may be a structure in which the outer tube 112 surrounds the entire outer periphery of the inner tube 111 as shown in FIG. 7A, or a part of the outer periphery of the inner tube 111 as shown in FIG. 7B. (In this example, a half circumference) may be configured to be surrounded by the outer tube 113. A pipe line between the inner pipe 111 and the outer pipe 112 or 113 is connected to a steam supply pipe 15, in which steam is supplied from a steam supply source (not shown) and sterile (or sterilized) air (gas) not shown is supplied. Sterile (or sterile) air (gas) can be selectively supplied from the source. As shown in FIG. 8, each of the nozzles 21 and 41 is attached to the double-structured pipes 11 and 31 by attaching a mounting member 115 to the end of the inner pipe 111 and the outer pipe 112 or 113 at the end of the pipe. Are joined by welding or the like, and the nozzle 21 or 41 is attached via the attachment member 115. Since the nozzles 21 and 41 may have a known structure, detailed description will be omitted. Since the nozzle is made of stainless steel, the heat efficiency is high and the heating effect is high, so that a sufficient sterilizing effect can be obtained even at the nozzle portion. At the ends of the pipes 11 and 31, it is further necessary to provide a passage for discharging the steam sent into the pipe between the inner pipe and the outer pipe. In this embodiment, a pipe 116 for connecting the discharge pipe is attached to the end of the outer pipe 112 or 113 by welding or the like so that the steam flow contacts the mounting member 115 to efficiently heat the mounting member. . More specifically, the inner pipe 111 and the outer pipe 112 are connected by connecting a portion of the inner face of the pipe 116 on the distal end side of the pipe so as to be substantially flush with the upper face (see FIG. 8) of the flange portion of the mounting member 115. Or the steam flowing in the conduit between 113 and 113 is in sufficient contact with the mounting member to heat it and raise the temperature of the nozzle so that it can be kept dry. As the material of the pipe having the double structure, stainless steel is preferable in order to prevent corrosion, and more specifically, it is preferable to use a sanitary specification having no seams. However, seamless pipes of other materials can also be used. The double pipe can be used as long as it is made of a material that can withstand high temperature and pressure of steam and has high thermal conductivity.
[0014]
As shown in FIG. 4, the middle pipe 12 of the cleaning sterilization system 10 has a portion 12 a extending vertically along a side wall and (or a partition wall) defining them in the CR 1, and a lateral direction at an upper position. A plurality of nozzles 22 are attached to the pipes vertically or horizontally. As shown in FIG. 5, the middle pipe 32 of the cleaning / sterilizing system 30 has a portion 32a extending vertically along a side wall and / or a partition wall defining the same within the CR2, and a horizontal portion 32 at an upper position. And a plurality of nozzles 42 attached to the pipes vertically or horizontally. The middle and lower pipes are also preferably made of a material that does not easily corrode, such as stainless steel, and more specifically, it is desirable to use a material having a seamless sanitary specification. However, seamless pipes of other materials can also be used.
[0015]
The pipe line between the inner pipe and the outer pipe of the double-structured pipes 11 and 31 can be connected not only to the steam supply source as described above, but also to a sterile air supply source via a valve (not shown). It is possible to supply sterile air into the pipeline. Further, the inner pipe 111 and the other pipes 12, 13, 32, and 33 of the pipe having the double structure are connected to the supply pipe 16 outside the CR1 and CR2, and the supply pipe is connected to a sterile water through a valve (not shown). Connected to source. The supply pipe 16 can be connected to a supply source of cleaning and disinfectant (none is shown) through a valve, and is connected to a supply source of sterile air (none is shown) through a valve. Can also be connected.
In a structure in which a plurality of nozzles are attached to one pipe, as shown in FIG. 9, an area A for simultaneously disinfecting and spraying the cleaning liquid is defined at once, and a nozzle in the area is sandwiched therebetween. Sterile air is supplied from both sides of the pipe so that there is no difference in the efficiency of sterilization and foaming of the cleaning liquid. That is, in the pipes 12, 13, 32, or 33 to which the plurality of nozzles 22, 23, 42, or 43 are attached, an area A for simultaneously disinfecting and spraying the cleaning liquid is determined at once, and the pipes are provided at both ends of the area. A supply pipe 17 for sterile air is connected, and the supply pipe is connected to a sterile air supply source via a valve (not shown). By doing so, when spraying the cleaning and sterilizing liquid from the nozzles present in the area, sterile air was supplied into the piping from the air supply pipes on both sides of the area, and the cleaning and the sterilizing agent were foamed. Spray the sterilizing solution from the nozzle in the state. By supplying aseptic air from both sides into the pipe in the desired area, foaming of the sterilizing solution can be homogenized, and foaming efficiency can be increased and uniformized.
[0016]
Next, the operation of the cleaning / sterilizing system will be described by taking the operation of the cleaning / sterilizing system for CR1 as an example, but the operation of the cleaning / sterilizing system of CR2 is the same, so the description is omitted.
First, steam is supplied from a steam supply source to a pipe line between the inner pipe 111 and the outer pipe 112 from the steam supply pipe of the upper pipe 11 to heat the inner pipe 111 to sterilize the inside of the inner pipe. Thereafter, sterile air or sterile gas is supplied between the inner pipe 111 and the outer pipe 112 from a supply source of sterile air (not shown) to cool the pipe 11.
Next, sterile water is supplied into the inner pipes of the upper-layer double-structure pipes 11, 31 and the middle- and lower-layer single-structure pipes 12, 13, 32, and 33, and the pipes are filled with sterile water. After that, first, concentrated sterilizing and cleaning liquids are supplied into the lower pipe 13 and sterile air is supplied into the pipes to sterilize and foam the cleaning liquid, and the sterilizing liquid is sprayed from the nozzles. After the sterilization from the lower pipe and the spraying of the cleaning liquid are completed, concentrated sterilization and cleaning liquid are supplied into the middle pipe 12, and sterile air is supplied into the pipe to sterilize from the nozzle while the sterilizing liquid is foamed. Spray the cleaning solution. Thereafter, sterilizing and cleaning liquid is supplied into the inner pipe 111 of the pipe 11 and sterile air is supplied into the pipe, and the sterilizing liquid is sprayed from the nozzle in a state where the sterilizing liquid is foamed. When the sterilizing and cleaning liquid is foamed and sprayed, as described above, the area to be sprayed is divided in advance, and aseptic air is sent to the pipe from both ends of the area to uniform the foaming efficiency.
[0017]
After the disinfecting of the germicidal solution is completed in the CR 1, the system waits for a predetermined time to maintain the effect of the germicide. And sterile water is sprayed from each nozzle to wash out the sterilizing solution in CR1. Thereafter, sterile air is supplied into all the pipes 11 (the inner pipe in the case of the lower pipe 11), 12 and 13, and the water remaining in the pipes and the nozzles is blown off from each nozzle. Finally, steam flows between the inner pipe 111 and the outer pipe of the upper pipe 11 to heat and sterilize the pipe 11 and the nozzle attached to the pipe. When the pipe 11 is heated with steam, the inner pipe is heated and dried therein, and the outer circumference of the inner pipe and / or the outer circumference of the outer pipe 112 are also heated and moisture adhering to the outer peripheral surface is dried, Further, the nozzle is also heated, and moisture adhering to the nozzle is also dried. This completes a series of cleaning and disinfecting operations.
[0018]
【The invention's effect】
According to the present invention, the following effects can be obtained.
(A) The inside and the outer periphery of the pipe in the CR can be sterilized, and it is possible to prevent contamination of the lower filling material due to mixing of various bacteria.
(B) It becomes possible to semi-automate or automate the cleaning and sterilizing operation in the CR.
(C) Since no packing is used at the nozzle mounting portion at the end of the pipe, the efficiency of heat conduction to the nozzle is improved, and a sufficient heating effect of the nozzle is obtained.
(D) By using a sanitary specification pipe, a double pipe can be made with only two pipes without making a joint in the CR. In addition, since the surface can be polished, the surface can be smoothed, whereby an effect that bacteria are hardly adhered is obtained, and it can withstand high temperature and high pressure.
[Brief description of the drawings]
FIG. 1 is a schematic plan view of a clean room for a beverage filling facility equipped with the cleaning and sterilizing system of the present invention, showing an upper pipe and an arrangement of nozzles attached thereto.
FIG. 2 is a schematic plan view of the clean room shown in FIG. 1, showing an arrangement of a middle pipe and nozzles attached thereto.
FIG. 3 is a schematic plan view of the clean room shown in FIG. 1, showing a lower pipe and an arrangement of nozzles attached thereto.
FIG. 4 is a diagram showing an arrangement of pipes in a clean room CR1 shown in FIGS. 1 to 3 and nozzles attached thereto.
FIG. 5 is a diagram showing an arrangement of pipes in a clean room CR2 shown in FIGS. 1 to 3 and nozzles attached thereto.
FIG. 6 is a plan view showing an example of a pipe having a double structure.
FIG. 7 is an enlarged cross-sectional view showing an example of a pipe having a double structure.
FIG. 8 is an enlarged sectional view showing a state in which a nozzle is attached to an upper pipe.
FIG. 9 is a diagram illustrating a method of supplying sterile air to a pipe.
[Explanation of symbols]
10, 30 Cleaning and sterilization system 11, 12, 13, 31, 32, 33 Piping 21, 22, 23, 41, 42, 43 Nozzle 15 Steam supply pipe 16 Supply pipe CR1, CR2 Clean room

Claims (13)

In clean room cleaning and sterilization systems,
A pipe for supplying sterilization, a cleaning liquid and a rinsing liquid in the clean room,
At least one nozzle that is attached to a predetermined position of the pipe and injects sterilization, cleaning liquid and rinsing liquid into the clean room,
At least a part of the pipes has a double structure including an inner pipe and an outer pipe surrounding at least a part of the inner pipe in a circumferential direction, and the inner pipe and the outer pipe are provided with steam between the outer pipe and the inner pipe. A washing and sterilizing system, wherein the inside of the tube and at least the outer periphery of the outer tube can be heated and sterilized. The clean room cleaning / sterilizing system according to claim 1,
A washing and sterilizing system in which the pipes are arranged in a plurality of stages at different heights in the vertical direction, and at least the uppermost pipe has the double structure. The cleaning and sterilizing system for a clean room according to claim 1 or 2,
A cleaning and sterilizing system characterized by disposing a nozzle attached to the pipe as close to the pipe as possible, thereby transferring the heat of the pipe to the nozzle, thereby increasing the temperature of the nozzle and keeping it in a dry state. The cleaning and sterilizing system for a clean room according to any one of claims 1 to 3,
A cleaning and sterilizing system, wherein the pipe is of a sanitary specification. In the clean room cleaning sterilization method,
A pipe for supplying sterilization, a cleaning liquid and a rinsing liquid into the clean room, wherein at least a part of the pipe has a double structure having an inner pipe and an outer pipe surrounding at least a part of a circumferential direction of the inner pipe. Piping, at least one nozzle that is attached to a predetermined position of the piping and injects sterilization, a cleaning liquid and a rinsing liquid into the clean room,
The sterilization, cleaning solution, rinsing solution and sterile gas are injected in the order of time in the clean room through the pipe and the nozzle,
Thereafter, drying and sterilization in the inner tube and at least drying and sterilization of the outer periphery of the outer tube are performed by passing steam between the inner tube and the outer tube. The method for cleaning and sterilizing a clean room according to claim 5,
A method for cleaning and sterilizing, comprising adding a sterile gas to the sterilizing and cleaning liquid to foam the liquid when spraying the sterilizing and cleaning liquid into the clean room. In the method for cleaning and sterilizing a clean room according to claim 6,
A method of cleaning and sterilizing, wherein sterile gas is introduced into the pipe from both sides of an area where the nozzle is installed to reduce a difference in foaming efficiency from the nozzle in the area. The method for cleaning and sterilizing a clean room according to any one of claims 5 to 7,
A cleaning and sterilizing method, characterized in that steam is passed between the inner pipe and the outer pipe of the double-structured pipe to sterilize and dry prior to the sterilization and the supply of the cleaning liquid into the pipe. In the method for cleaning and sterilizing a clean room according to claim 8,
A washing and sterilizing method, characterized in that steam is flowed between the inner pipe and the outer pipe of the double-structured pipe and then cooled by flowing a cooling gas. The method for cleaning and sterilizing a clean room according to any one of claims 5 to 9,
A cleaning and sterilizing method characterized by disposing a nozzle attached to the pipe as close as possible to the pipe, thereby transmitting heat of the pipe to the nozzle, thereby increasing the temperature of the nozzle and keeping it dry. In the residual liquid prevention and sterilization structure of the pipe that sterilizes by eliminating the residual liquid that adheres to the inside and outside of the pipe in the clean room cleaning sterilization system,
The pipe to be subjected to the prevention and sterilization of the residual liquid has a double structure having an inner pipe and an outer pipe surrounding at least a part of the inner pipe in a circumferential direction, and steam is passed between the inner pipe and the outer pipe. A residual liquid preventing and sterilizing structure for piping, wherein the inside of the inner tube and at least the outer periphery of the outer tube can be dried and sterilized. The method for preventing residual liquid and sterilizing pipes according to claim 11,
Sterilization in the inner tube, after supplying the cleaning liquid and the rinsing liquid at different times, introducing a sterile gas into the inner tube to discharge the residual liquid in the inner tube, and then, the inner tube and the outer tube A method for preventing residual liquid from pipes and disinfecting the pipes, comprising sending steam between the pipes. In a method of disinfecting the clean room through a pipe and at least one nozzle attached to the pipe, foaming and spraying a cleaning liquid,
A method for injecting a sterilizing and cleaning liquid, characterized in that sterile gas is introduced from both sides of a nozzle installation region of the pipe to reduce a difference in foaming efficiency from a nozzle between the two.

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