JP2004184363A - Alpha-ray irradiator - Google Patents

Alpha-ray irradiator Download PDF

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Publication number
JP2004184363A
JP2004184363A JP2002354719A JP2002354719A JP2004184363A JP 2004184363 A JP2004184363 A JP 2004184363A JP 2002354719 A JP2002354719 A JP 2002354719A JP 2002354719 A JP2002354719 A JP 2002354719A JP 2004184363 A JP2004184363 A JP 2004184363A
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JP
Japan
Prior art keywords
alpha
ray
sample
ray source
section
Prior art date
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Pending
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JP2002354719A
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Japanese (ja)
Inventor
Yutaka Yamada
裕 山田
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
National Institute of Radiological Sciences
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National Institute of Radiological Sciences
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Priority to JP2002354719A priority Critical patent/JP2004184363A/en
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Abstract

<P>PROBLEM TO BE SOLVED: To provide an alpha-ray irradiator which easily and efficiently irradiates objects with alpha rays. <P>SOLUTION: The irradiator is equipped with a sample holding section for holding a sample to be irradiated with the alpha rays, an alpha-ray source section for irradiating the sample with the alpha rays, an alpha-ray source fixing section for fixing the alpha-ray source section, a collimator section for adjusting the irradiation angles of the alpha rays in an approximately vertical direction and a shutter section for selecting the time for alpha-ray irradiation by opening and closing a shutter. Preferably, the irradiator is equipped with a distance adjustment mechanism for adjusting the distance from the alpha-ray source to the sample. <P>COPYRIGHT: (C)2004,JPO&NCIPI

Description

【0001】
【発明の属する技術分野】
本発明はアルファ線照射装置に関する。
【0002】
【従来の技術】
従来、被照射試料にアルファ線を照射してその影響を評価するために、アルファ線照射装置が利用されている。このアルファ線照射装置は、たとえば培養細胞に対するアルファ線照射の影響を調べるために、コリメーターを通った放射線を照射しうるように構成されている。
【0003】
しかしながら、従来のアルファ線照射装置は、照射時間、特に数分の1秒〜数10分の1秒という短い照射時間を正確に設定できない、また線源から試料までの距離を正確かつ任意に調節できない、さらにはアルファ線源の回りの気相を置換できないことから必ずしも簡便にかつ効率よく照射しうるものではない。
【0004】
【発明が解決しようとする課題】
本発明は、簡便にかつ効率よくアルファ線を照射しうるアルファ線照射装置を提供する。
【0005】
【課題を解決するための手段】
本発明のアルファ線照射装置は、アルファ線を照射される試料を保持するための試料保持部、アルファ線を照射するアルファ線源部、アルファ線源部を固定するためのアルファ線源固定部、アルファ線の照射角度を略垂直に調整するためのコリメーター部、ならびにアルファ線照射時間をシャッターの開閉により選定するためのシャッター部、を備えてなる。
【0006】
本発明のアルファ線照射装置において、試料保持部はアルファ線を照射される試料を保持し、その下部に試料、たとえば培養皿に入った細胞を装填し、好適には試料の高さを調節しうるように構成されている。そのような調節は、たとえば、高さ調整リングを回すことにより高さを変動しうる機構が挙げられる。アルファ線源部は、アルファ線源およびそれを支持する線源台からなり、アルファ線源固定部によりアルファ線源の高さを調節し、固定する。アルファ線源固定部は、アルファ線の回りの気相を置換するために、ヘリウム等の入気管と排気管を備えてなるのが好適であり、これにより空気によるアルファ線の減衰を防止しうる。
【0007】
アルファ線源部と試料保持部の間には、アルファ線の照射角度を略垂直に調整するためのコリメーター部が設けられる。このコリメーター部はハニカム状の略垂直な開口を有するのが好適である。そしてこのコリメーター部と試料保持部との間にシャッターが備えられている。シャッターとしてはカメラにおけるレンズシャッターもしくはフォーカルプレンシャッターと同様な基本構成とし得る。試料保持部の下部には試料が充填され、シャッター部を開けると試料保持部の低部よりアルファ線が試料に照射されることになる。本発明におけるシャッター部はアルファ線照射時間をコントローラーにより任意に調節しうる。
【0008】
【発明の実施の形態】
以下、図1により本発明をさらに詳細に説明する。図1は本発明のアルファ線照射装置の1例(卓上型)を示す断面略図である。細胞培養皿1は試料保持部2の下部に装填され、試料高さ調節リング3により、高さを調節される。4はシャッター、5はコリメーター、6はシャッターステージであり、7はアルファ線源、8は線源台、そして9はアルファ線源調節ボルトである。さらに10は下部カバーである。シャッター4が開かれているときには、アルファ線はアルファ線源7によりコリメーター5の開口を通って試料に照射される。
【0009】
コリメーター5はアルファ線の照射角度を略垂直に調整するためにハニカム状の略垂直な開口を有する(図2)。シャッター4はシャッターステージ6に搭載されており、コントローラー(図示せず)により、任意の所定時間開くことにより照射時間を選定しうる。アルファ線源7は線源台8の上に搭載され、線源調節ボルト9によりコリメーターに密着・固定されうる。線源台8および線源調節ボルト9がアルファ線固定部を構成する。
【0010】
アルファ線照射に際しては、まずアルファ線源7、ついでコリメーター5を取付け、シャッター4本体を所定位置にセットし、さらに試料高さ調節リング3により、試料高さを調節する。コントローラー(図示せず)をシャッター4本体にレリースケーブルで接続する。ついで、細胞培養皿1を試料保持部2の下部に装填し、所定のシャッター速度を選択し、アルファ線を照射する。
【0011】
【発明の効果】
本発明によれば、簡便にかつ効率よくアルファ線を照射しうるアルファ線照射装置を提供しうる。
【図面の簡単な説明】
【図1】本発明のアルファ線照射装置の1例(卓上型)を示す断面略図。
【図2】本発明のアルファ線照射装置におけるコリメーターの1例を示す概略図。
【符号の説明】
1…細胞培養皿
2…試料保持部
3…試料高さ調節リング
4…シャッター
5…コリメーター
6…シャッターステージ
7…アルファ線源
8…線源台
9…アルファ線源調節ボルト
10…下部カバー
[0001]
TECHNICAL FIELD OF THE INVENTION
The present invention relates to an alpha ray irradiation device.
[0002]
[Prior art]
BACKGROUND ART Conventionally, an alpha-ray irradiator has been used to irradiate a sample to be irradiated with alpha-rays and evaluate the influence. The alpha-irradiation apparatus is configured to be capable of irradiating radiation that has passed through a collimator, for example, to investigate the effect of alpha-irradiation on cultured cells.
[0003]
However, conventional alpha-ray irradiators cannot accurately set the irradiation time, especially a short irradiation time of a fraction of a second to a tenth of a second, and can accurately and arbitrarily adjust the distance from the source to the sample. Irradiation cannot be performed simply and efficiently because the gas phase around the alpha-ray source cannot be replaced.
[0004]
[Problems to be solved by the invention]
The present invention provides an alpha-ray irradiator that can easily and efficiently irradiate alpha-rays.
[0005]
[Means for Solving the Problems]
The alpha ray irradiation apparatus of the present invention is a sample holding unit for holding a sample to be irradiated with alpha rays, an alpha ray source unit for irradiating alpha rays, an alpha ray source fixing unit for fixing the alpha ray source unit, A collimator unit for adjusting the irradiation angle of the alpha ray to be substantially vertical, and a shutter unit for selecting the alpha ray irradiation time by opening and closing the shutter are provided.
[0006]
In the alpha ray irradiation apparatus of the present invention, the sample holding section holds a sample to be irradiated with alpha rays, and loads a sample, for example, cells in a culture dish, below the sample, preferably adjusts the height of the sample. It is configured to receive. Such adjustment includes, for example, a mechanism that can vary the height by turning a height adjustment ring. The alpha-ray source unit includes an alpha-ray source and a source table that supports the alpha-ray source. The alpha-source fixing unit adjusts and fixes the height of the alpha-ray source. The alpha source fixing part preferably includes an inlet pipe and an exhaust pipe made of helium or the like in order to replace a gas phase around the alpha ray, thereby preventing attenuation of the alpha ray by air. .
[0007]
A collimator section is provided between the alpha ray source section and the sample holding section for adjusting the irradiation angle of the alpha ray substantially vertically. This collimator section preferably has a honeycomb-shaped substantially vertical opening. A shutter is provided between the collimator and the sample holder. The shutter may have the same basic configuration as a lens shutter or a focal plane shutter in a camera. The lower part of the sample holder is filled with the sample, and when the shutter is opened, the sample is irradiated with alpha rays from the lower part of the sample holder. In the shutter unit according to the present invention, the alpha-ray irradiation time can be arbitrarily adjusted by a controller.
[0008]
BEST MODE FOR CARRYING OUT THE INVENTION
Hereinafter, the present invention will be described in more detail with reference to FIG. FIG. 1 is a schematic sectional view showing an example (tabletop type) of an alpha-ray irradiation apparatus according to the present invention. The cell culture dish 1 is loaded in the lower part of the sample holding unit 2, and the height is adjusted by a sample height adjusting ring 3. 4 is a shutter, 5 is a collimator, 6 is a shutter stage, 7 is an alpha source, 8 is a source stage, and 9 is an alpha source adjusting bolt. 10 is a lower cover. When the shutter 4 is open, the sample is irradiated with alpha rays through the aperture of the collimator 5 by the alpha ray source 7.
[0009]
The collimator 5 has a honeycomb-shaped substantially vertical opening for adjusting the irradiation angle of the alpha ray to be almost vertical (FIG. 2). The shutter 4 is mounted on a shutter stage 6, and the irradiation time can be selected by opening the shutter 4 at an arbitrary predetermined time by a controller (not shown). The alpha ray source 7 is mounted on a source table 8 and can be closely attached and fixed to a collimator by a source adjusting bolt 9. The source table 8 and the source adjusting bolt 9 constitute an alpha ray fixing unit.
[0010]
When irradiating with alpha rays, first, the alpha ray source 7 and then the collimator 5 are attached, the shutter 4 main body is set at a predetermined position, and the sample height is adjusted by the sample height adjusting ring 3. A controller (not shown) is connected to the shutter 4 main body with a release cable. Next, the cell culture dish 1 is loaded in the lower part of the sample holder 2, a predetermined shutter speed is selected, and alpha rays are irradiated.
[0011]
【The invention's effect】
ADVANTAGE OF THE INVENTION According to this invention, the alpha-ray irradiation apparatus which can irradiate an alpha-ray easily and efficiently can be provided.
[Brief description of the drawings]
FIG. 1 is a schematic cross-sectional view showing an example (tabletop type) of an alpha-ray irradiation device of the present invention.
FIG. 2 is a schematic diagram showing an example of a collimator in the alpha-ray irradiation device of the present invention.
[Explanation of symbols]
DESCRIPTION OF SYMBOLS 1 ... Cell culture dish 2 ... Sample holder 3 ... Sample height adjustment ring 4 ... Shutter 5 ... Collimator 6 ... Shutter stage 7 ... Alpha ray source 8 ... Source table 9 ... Alpha ray source adjustment bolt 10 ... Lower cover

Claims (8)

アルファ線を照射される試料を保持するための試料保持部、アルファ線を照射するアルファ線源部、アルファ線源部を固定するためのアルファ線源固定部、アルファ線の照射角度を略垂直に調整するためのコリメーター部、ならびにアルファ線照射時間をシャッターの開閉により選定するためのシャッター部、を備えてなることを特徴とするアルファ線照射装置。A sample holder for holding a sample to be irradiated with alpha rays, an alpha ray source section for emitting alpha rays, an alpha ray source fixing section for fixing the alpha ray source section, and an irradiation angle of the alpha rays to be substantially vertical. An alpha-ray irradiator comprising: a collimator section for adjusting; and a shutter section for selecting an alpha-ray irradiation time by opening and closing a shutter. 該アルファ線源から該試料までの距離を調節するための距離調節機構をさらに備えてなる請求項1記載のアルファ線照射装置。The alpha ray irradiation apparatus according to claim 1, further comprising a distance adjusting mechanism for adjusting a distance from the alpha ray source to the sample. アルファ線源固定部が、アルファ線の回りの気相を置換するために、入気管と排気管を備えてなる請求項1記載のアルファ線照射装置。2. The alpha-ray irradiation apparatus according to claim 1, wherein the alpha-ray source fixing unit includes an intake pipe and an exhaust pipe for replacing a gas phase around the alpha-ray. 距離調節機構が、試料保持部に設けられている請求項2記載のアルファ線照射装置。The alpha ray irradiation device according to claim 2, wherein the distance adjusting mechanism is provided on the sample holding unit. 距離調節機構が試料高さ調整リングである請求項2記載のアルファ線照射装置。The alpha ray irradiation device according to claim 2, wherein the distance adjusting mechanism is a sample height adjusting ring. コリメーター部がハニカム状の略垂直な開口を有する請求項1記載のアルファ線照射装置。2. The alpha-ray irradiator according to claim 1, wherein the collimator has a honeycomb-shaped substantially vertical opening. 試料が培養細胞である請求項1記載のアルファ線照射装置。The alpha ray irradiation device according to claim 1, wherein the sample is a cultured cell. アルファ線源部がアルファ線源およびそれを支持する線源台からなる請求項1記載のアルファ線照射装置。2. The alpha-ray irradiation apparatus according to claim 1, wherein the alpha-ray source section comprises an alpha-ray source and a source base supporting the alpha-ray source.
JP2002354719A 2002-12-06 2002-12-06 Alpha-ray irradiator Pending JP2004184363A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010091387A (en) * 2008-10-07 2010-04-22 Mitsubishi Heavy Ind Ltd Radiation irradiator of non-fixed type
JP2011007733A (en) * 2009-06-29 2011-01-13 Japan Atomic Energy Agency Radiation irradiation device
CN103820317A (en) * 2014-01-21 2014-05-28 苏州大学 Alpha source irradiation device for cell experiments

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010091387A (en) * 2008-10-07 2010-04-22 Mitsubishi Heavy Ind Ltd Radiation irradiator of non-fixed type
JP2011007733A (en) * 2009-06-29 2011-01-13 Japan Atomic Energy Agency Radiation irradiation device
CN103820317A (en) * 2014-01-21 2014-05-28 苏州大学 Alpha source irradiation device for cell experiments
CN103820317B (en) * 2014-01-21 2015-08-19 苏州大学 For the α source irradiating unit of cell experiment

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