JP2003528577A - 身体組織の分化転換方法 - Google Patents

身体組織の分化転換方法

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Publication number
JP2003528577A
JP2003528577A JP2001513421A JP2001513421A JP2003528577A JP 2003528577 A JP2003528577 A JP 2003528577A JP 2001513421 A JP2001513421 A JP 2001513421A JP 2001513421 A JP2001513421 A JP 2001513421A JP 2003528577 A JP2003528577 A JP 2003528577A
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JP
Japan
Prior art keywords
cells
transdifferentiation
guanosine
cell
agent
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Pending
Application number
JP2001513421A
Other languages
English (en)
Japanese (ja)
Other versions
JP2003528577A5 (https=
Inventor
バラノヴィッツ，スティーブン
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Individual
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Individual
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Application filed by Individual filed Critical Individual
Publication of JP2003528577A publication Critical patent/JP2003528577A/ja
Publication of JP2003528577A5 publication Critical patent/JP2003528577A5/ja
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/01—Modulators of cAMP or cGMP, e.g. non-hydrolysable analogs, phosphodiesterase inhibitors, cholera toxin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C12N2501/38—Hormones with nuclear receptors
    • C12N2501/385—Hormones with nuclear receptors of the family of the retinoic acid recptor, e.g. RAR, RXR; Peroxisome proliferator-activated receptor [PPAR]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/30—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from cancer cells, e.g. reversion of tumour cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2001513421A 1999-07-29 2000-07-31 身体組織の分化転換方法 Pending JP2003528577A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US14627299P 1999-07-29 1999-07-29
US60/146,272 1999-07-29
US16855599P 1999-12-02 1999-12-02
US60/168,555 1999-12-02
PCT/US2000/021015 WO2001008691A1 (en) 1999-07-29 2000-07-31 Methods for transdifferentiation of body tissues

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2011021729A Division JP2011139705A (ja) 1999-07-29 2011-02-03 身体組織の分化転換方法

Publications (2)

Publication Number Publication Date
JP2003528577A true JP2003528577A (ja) 2003-09-30
JP2003528577A5 JP2003528577A5 (https=) 2007-10-04

Family

ID=26843741

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2001513421A Pending JP2003528577A (ja) 1999-07-29 2000-07-31 身体組織の分化転換方法
JP2011021729A Withdrawn JP2011139705A (ja) 1999-07-29 2011-02-03 身体組織の分化転換方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2011021729A Withdrawn JP2011139705A (ja) 1999-07-29 2011-02-03 身体組織の分化転換方法

Country Status (7)

Country Link
US (2) US6670397B1 (https=)
EP (1) EP1200101A4 (https=)
JP (2) JP2003528577A (https=)
AU (1) AU782396B2 (https=)
CA (1) CA2378140A1 (https=)
IL (2) IL147669A0 (https=)
WO (1) WO2001008691A1 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011155984A (ja) * 2000-05-10 2011-08-18 Tristem Trading (Cyprus) Ltd 装置
WO2021201170A1 (ja) * 2020-03-31 2021-10-07 スカイファーマ株式会社 医薬有効成分のスクリーニング方法、製造方法及び設計方法

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1200101A4 (en) * 1999-07-29 2003-02-05 Steven Baranowitz METHODS FOR TRANSDIFFERENTIATING BODY TISSUES
US20070087993A1 (en) * 1999-07-29 2007-04-19 Steven Baranowitz Method for transdifferentiation of body tissues
US8609412B2 (en) 1999-08-05 2013-12-17 Regents Of The University Of Minnesota Mapc generation of lung tissue
US8252280B1 (en) 1999-08-05 2012-08-28 Regents Of The University Of Minnesota MAPC generation of muscle
US7015037B1 (en) 1999-08-05 2006-03-21 Regents Of The University Of Minnesota Multiponent adult stem cells and methods for isolation
US10638734B2 (en) 2004-01-05 2020-05-05 Abt Holding Company Multipotent adult stem cells, sources thereof, methods of obtaining and maintaining same, methods of differentiation thereof, methods of use thereof and cells derived thereof
WO2002064748A2 (en) 2001-02-14 2002-08-22 Furcht Leo T Multipotent adult stem cells, sources thereof, methods of obtaining and maintaining same, methods of differentiation thereof, methods of use thereof and cells derived thereof
WO2001011011A2 (en) 1999-08-05 2001-02-15 Mcl Llc Multipotent adult stem cells and methods for isolation
US6864243B1 (en) 2000-05-12 2005-03-08 Inspire Pharmaceuticals, Inc. Method for treating retinal degeneration with purinergic receptor agonists
AU2003202988A1 (en) * 2002-01-14 2003-07-30 The Board Of Trustees Of The University Of Illinois Use of modified pyrimidine compounds to promote stem cell migration and proliferation
US20060228798A1 (en) 2002-11-27 2006-10-12 Catherine Verfaillie Homologous recombination in multipotent adult progenitor cells
AU2003300012A1 (en) * 2002-12-30 2004-07-29 Indiana University Research & Technology Corporation Method of treatment for central nervous system injury
JP2007508816A (ja) * 2003-10-10 2007-04-12 ゲ・ミン・ルイ 細胞培養および組織培養プラットフォームのための組成物および方法
RU2319132C2 (ru) * 2005-08-24 2008-03-10 Надежда Витальевна Корсакова Усовершенствованный способ выявления клеточных структур в хрусталике глаза экспериментальных животных
CN101310012B (zh) 2005-10-14 2012-05-09 明尼苏达大学董事会 非胚胎干细胞分化成具有胰腺表型的细胞
WO2008063675A2 (en) 2006-11-24 2008-05-29 Regents Of The University Of Minnesota Endodermal progenitor cells
US7897363B2 (en) * 2007-06-12 2011-03-01 Phylonix Pharmaceuticals, Inc. Methods of screening an agent for an activity in an isolated eye of a teleost
AU2009205886B2 (en) 2008-01-18 2015-08-27 Katholieke Universiteit Leuven Stem cell aggregates and methods for making and using
WO2010049752A1 (en) 2008-10-31 2010-05-06 Katholieke Universiteit Leuven Optimized methods for differentiation of cells into cells with hepatocyte and hepatocyte progenitor phenotypes, cells produced by the methods, and methods for using the cells
TWI450228B (zh) * 2010-01-15 2014-08-21 私立中原大學 A method of simulating spinal surgery on a computer system
SG185526A1 (en) 2010-05-12 2012-12-28 Abt Holding Co Modulation of splenocytes in cell therapy
WO2011158125A2 (en) 2010-06-17 2011-12-22 Katholieke Universiteit Leuven Methods for differentiating cells into hepatic stellate cells and hepatic sinusoidal endothelial cells, cells produced by the methods, and methods for using the cells
EP2609191B1 (en) 2010-08-24 2017-11-22 Regents Of The University Of Minnesota Non-static suspension culture of cell aggregates
IL289870B2 (en) 2013-04-12 2023-03-01 Lafrancesca Saverio Improving organs for transplantation
CA2978109A1 (en) 2015-03-31 2016-10-06 The University Of North Carolina At Chapel Hill Delivery vehicles for stem cells and uses thereof
NL2019618B1 (en) 2017-09-22 2019-03-28 Ncardia B V In vitro method for providing stem cell derived cardiomyocytes
JP2020537522A (ja) 2017-10-13 2020-12-24 イーエムベーアー−インスティテュート フュール モレクラレ バイオテクノロジー ゲゼルシャフト ミット ベシュレンクテル ハフツング 体細胞の増強された再プログラミング

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7319994A (en) * 1993-06-30 1995-01-24 Board Of Regents, The University Of Texas System Nucleotide preparation and uses thereof in wound healing
US6087168A (en) * 1999-01-20 2000-07-11 Cedars Sinai Medical Center Conversion of non-neuronal cells into neurons: transdifferentiation of epidermal cells
EP1200101A4 (en) * 1999-07-29 2003-02-05 Steven Baranowitz METHODS FOR TRANSDIFFERENTIATING BODY TISSUES

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011155984A (ja) * 2000-05-10 2011-08-18 Tristem Trading (Cyprus) Ltd 装置
WO2021201170A1 (ja) * 2020-03-31 2021-10-07 スカイファーマ株式会社 医薬有効成分のスクリーニング方法、製造方法及び設計方法

Also Published As

Publication number Publication date
US6670397B1 (en) 2003-12-30
IL147669A0 (en) 2002-08-14
JP2011139705A (ja) 2011-07-21
IL147669A (en) 2009-05-04
EP1200101A1 (en) 2002-05-02
AU782396B2 (en) 2005-07-21
WO2001008691A1 (en) 2001-02-08
AU6754500A (en) 2001-02-19
US7176189B2 (en) 2007-02-13
US20030229008A1 (en) 2003-12-11
CA2378140A1 (en) 2001-02-08
EP1200101A4 (en) 2003-02-05

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