JP2003524369A5 - - Google Patents

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Publication number
JP2003524369A5
JP2003524369A5 JP2000509741A JP2000509741A JP2003524369A5 JP 2003524369 A5 JP2003524369 A5 JP 2003524369A5 JP 2000509741 A JP2000509741 A JP 2000509741A JP 2000509741 A JP2000509741 A JP 2000509741A JP 2003524369 A5 JP2003524369 A5 JP 2003524369A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2000509741A
Other languages
Japanese (ja)
Other versions
JP2003524369A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US1997/020023 external-priority patent/WO1999009064A1/en
Publication of JP2003524369A publication Critical patent/JP2003524369A/ja
Publication of JP2003524369A5 publication Critical patent/JP2003524369A5/ja
Pending legal-status Critical Current

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JP2000509741A 1997-08-19 1997-11-04 エピトープを有する主要組織適合複合体クラスiiエレメント/免疫グロブリンキメラ分子 Pending JP2003524369A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US5618597P 1997-08-19 1997-08-19
US60/056,185 1997-08-19
PCT/US1997/020023 WO1999009064A1 (en) 1997-08-19 1997-11-04 Epitope-bearing major histocompatibility complex class ii element/immunoglobulin chimeric molecules

Publications (2)

Publication Number Publication Date
JP2003524369A JP2003524369A (ja) 2003-08-19
JP2003524369A5 true JP2003524369A5 (uk) 2005-12-22

Family

ID=22002738

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000509741A Pending JP2003524369A (ja) 1997-08-19 1997-11-04 エピトープを有する主要組織適合複合体クラスiiエレメント/免疫グロブリンキメラ分子

Country Status (5)

Country Link
EP (1) EP1007567A4 (uk)
JP (1) JP2003524369A (uk)
AU (1) AU5428598A (uk)
CA (1) CA2301709C (uk)
WO (1) WO1999009064A1 (uk)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0889964A1 (en) 1996-03-28 1999-01-13 The Johns Hopkins University Soluble divalent and multivalent heterodimeric analogs of proteins
US6458354B1 (en) 1996-03-28 2002-10-01 The Johns Hopkins University Molecular complexes which modify immune responses
US6737057B1 (en) 1997-01-07 2004-05-18 The University Of Tennessee Research Corporation Compounds, compositions and methods for the endocytic presentation of immunosuppressive factors
US6268411B1 (en) 1997-09-11 2001-07-31 The Johns Hopkins University Use of multivalent chimeric peptide-loaded, MHC/ig molecules to detect, activate or suppress antigen-specific T cell-dependent immune responses
US20030007978A1 (en) * 1997-09-16 2003-01-09 Burrows Gregory G. Recombinant MHC molecules useful for manipulation of antigen-specific T-cells
BR9908082A (pt) * 1998-02-19 2000-10-31 Harvard College Proteìna de fusão do complexo de histocompatibilidade principal classe ii, conjugado dos domìnios de ligação do complexo de histocompatibilidade principal multimérico, processos para detectar células t tendo uma especificidade do complexo definido de mhc / peptìdeo, para conferir a um indivìduo imunidade adotiva a um complexo definido de mhc / peptìdeo, para estimular ou ativar as células t reativas a um complexo definido de mhc / peptìdeo, para seletivamente matar células t reativas a um complexo definido de mhc / peptìdeo, para tolerizar um indivìduo humano a um complexo definido de mhc / peptìdeo, e, ácido nucleico isolado
FR2796953B1 (fr) * 1999-07-29 2003-10-10 Centre Nat Rech Scient Proteines recombinantes, et complexes moleculaires derives de ces proteines, analogues a des molecules impliquees dans les reponses immunitaires
WO2001070245A1 (en) * 2000-03-22 2001-09-27 Corixa Corporation Immune mediators and related methods
US6811785B2 (en) 2001-05-07 2004-11-02 Mount Sinai School Of Medicine Of New York University Multivalent MHC class II—peptide chimeras
EP2783699A1 (en) 2003-09-05 2014-10-01 Oregon Health & Science University Monomeric recombinant MHC molecules useful for manipulation of antigen-specific T cells
WO2006077152A2 (en) * 2005-01-21 2006-07-27 Utku Nalan Hla fusion molecules and uses thereof
KR100754667B1 (ko) 2005-04-08 2007-09-03 한미약품 주식회사 비펩타이드성 중합체로 개질된 면역글로불린 Fc 단편 및이를 포함하는 약제학적 조성물

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5126433A (en) * 1986-08-21 1992-06-30 The Trustees Of Columbia University In The City Of New York Soluble forms of the t cell surface protein cd4
US5109123A (en) * 1988-06-14 1992-04-28 Dana Farber Cancer Institute Alteration of ability of soluble CD4 fragments to bind HIV
US5130297A (en) * 1988-06-23 1992-07-14 Anergen, Inc. Conjugates useful in ameliorating autoimmunity MHC-II-peptide
AU3220593A (en) * 1991-11-19 1993-06-15 Anergen, Inc. Soluble mhc molecules and their uses
US5820866A (en) * 1994-03-04 1998-10-13 National Jewish Center For Immunology And Respiratory Medicine Product and process for T cell regulation

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