JP2003511396A - 化学療法を増強する方法 - Google Patents
化学療法を増強する方法Info
- Publication number
- JP2003511396A JP2003511396A JP2001529267A JP2001529267A JP2003511396A JP 2003511396 A JP2003511396 A JP 2003511396A JP 2001529267 A JP2001529267 A JP 2001529267A JP 2001529267 A JP2001529267 A JP 2001529267A JP 2003511396 A JP2003511396 A JP 2003511396A
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- formula
- chemotherapeutic agent
- compound
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- salt
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- Pending
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- HAWPXGHAZFHHAD-UHFFFAOYSA-N mechlorethamine Chemical compound ClCCN(C)CCCl HAWPXGHAZFHHAD-UHFFFAOYSA-N 0.000 description 1
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- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 description 1
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- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 1
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 description 1
- 239000001488 sodium phosphate Substances 0.000 description 1
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- 239000008117 stearic acid Substances 0.000 description 1
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- ZSJLQEPLLKMAKR-GKHCUFPYSA-N streptozocin Chemical compound O=NN(C)C(=O)N[C@H]1[C@@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O ZSJLQEPLLKMAKR-GKHCUFPYSA-N 0.000 description 1
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- MNRILEROXIRVNJ-UHFFFAOYSA-N tioguanine Chemical compound N1C(N)=NC(=S)C2=NC=N[C]21 MNRILEROXIRVNJ-UHFFFAOYSA-N 0.000 description 1
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- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 description 1
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- KDQAABAKXDWYSZ-PNYVAJAMSA-N vinblastine sulfate Chemical compound OS(O)(=O)=O.C([C@H](C[C@]1(C(=O)OC)C=2C(=CC3=C([C@]45[C@H]([C@@]([C@H](OC(C)=O)[C@]6(CC)C=CCN([C@H]56)CC4)(O)C(=O)OC)N3C)C=2)OC)C[C@@](C2)(O)CC)N2CCC2=C1NC1=CC=CC=C21 KDQAABAKXDWYSZ-PNYVAJAMSA-N 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15832299P | 1999-10-08 | 1999-10-08 | |
| US60/158,322 | 1999-10-08 | ||
| PCT/US2000/027612 WO2001026467A1 (en) | 1999-10-08 | 2000-10-06 | Methods of enhancing chemotherapy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2003511396A true JP2003511396A (ja) | 2003-03-25 |
| JP2003511396A5 JP2003511396A5 (https=) | 2006-01-05 |
Family
ID=22567591
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001529267A Pending JP2003511396A (ja) | 1999-10-08 | 2000-10-06 | 化学療法を増強する方法 |
Country Status (7)
| Country | Link |
|---|---|
| EP (2) | EP2064951A1 (https=) |
| JP (1) | JP2003511396A (https=) |
| AT (1) | ATE426335T1 (https=) |
| AU (1) | AU782401B2 (https=) |
| CA (1) | CA2382727A1 (https=) |
| DE (1) | DE60041880D1 (https=) |
| WO (1) | WO2001026467A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003084543A1 (en) | 2002-04-10 | 2003-10-16 | Virginia Commonwealth University | Combination of glivec(sti571) with a cyclin-dependent kinase inhibitor, especially flavopiridol in the treatment of cancer |
| AU2003257329C1 (en) | 2002-08-19 | 2010-07-22 | Lorus Therapeutics Inc. | 2,4,5-trisubstituted imidazoles and their use as anti-microbial agents |
| US8969372B2 (en) | 2003-11-14 | 2015-03-03 | Aptose Boisciences Inc. | Aryl imidazoles and their use as anti-cancer agents |
| AU2006250809B2 (en) | 2005-05-25 | 2011-05-12 | Lorus Therapeutics Inc. | 2-indolyl imidazo(4,5-D)phenanthroline derivatives and their use in the treatment of cancer |
| EP2454943B1 (en) | 2010-11-23 | 2020-05-27 | GEA Food Solutions Bakel B.V. | Apparatus and method for the production of a product with an interleaver |
| WO2014153464A2 (en) | 2013-03-20 | 2014-09-25 | Lorus Therapeutics Inc. | 2-substituted imidazo[4,5-d]phenanthroline derivatives and their use in the treatment of cancer |
| ES2775579T3 (es) | 2013-10-04 | 2020-07-27 | Aptose Biosciences Inc | Composiciones para el tratamiento del cáncer |
| LU100887B1 (en) | 2017-02-24 | 2018-12-18 | Bioactor B V | Compounds and compositions against visceral hypersensitivity |
| CN111417395A (zh) | 2017-10-30 | 2020-07-14 | 艾普托斯生物科学公司 | 用于治疗癌症的芳基咪唑 |
| WO2022249192A1 (en) * | 2021-05-27 | 2022-12-01 | Ramot At Tel-Aviv University Ltd. | Broad-spectrum metastasis suppressing compounds and therapeutic uses thereof in human tumors |
| WO2025119974A1 (en) | 2023-12-04 | 2025-06-12 | Bioactor Bv | Naringin or naringenin for improving sleep quality |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4160452A (en) | 1977-04-07 | 1979-07-10 | Alza Corporation | Osmotic system having laminated wall comprising semipermeable lamina and microporous lamina |
| US4256108A (en) | 1977-04-07 | 1981-03-17 | Alza Corporation | Microporous-semipermeable laminated osmotic system |
| US4265874A (en) | 1980-04-25 | 1981-05-05 | Alza Corporation | Method of delivering drug with aid of effervescent activity generated in environment of use |
| US5700826A (en) * | 1995-06-07 | 1997-12-23 | Ontogen Corporation | 1,2,4,5-tetra substituted imidazoles as modulators of multi-drug resistance |
| US5756527A (en) * | 1995-06-07 | 1998-05-26 | Ontogen Corporation | Imidazole derivatives useful as modulators of multi drug resistances |
| US5840721A (en) | 1997-07-09 | 1998-11-24 | Ontogen Corporation | Imidazole derivatives as MDR modulators |
-
2000
- 2000-10-06 EP EP09004137A patent/EP2064951A1/en not_active Withdrawn
- 2000-10-06 EP EP00968797A patent/EP1221847B1/en not_active Expired - Lifetime
- 2000-10-06 CA CA002382727A patent/CA2382727A1/en not_active Abandoned
- 2000-10-06 AU AU78661/00A patent/AU782401B2/en not_active Ceased
- 2000-10-06 JP JP2001529267A patent/JP2003511396A/ja active Pending
- 2000-10-06 AT AT00968797T patent/ATE426335T1/de not_active IP Right Cessation
- 2000-10-06 WO PCT/US2000/027612 patent/WO2001026467A1/en not_active Ceased
- 2000-10-06 DE DE60041880T patent/DE60041880D1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| AU7866100A (en) | 2001-04-23 |
| EP1221847B1 (en) | 2009-03-25 |
| CA2382727A1 (en) | 2001-04-19 |
| ATE426335T1 (de) | 2009-04-15 |
| EP1221847A4 (en) | 2006-03-22 |
| AU782401B2 (en) | 2005-07-28 |
| EP2064951A1 (en) | 2009-06-03 |
| WO2001026467A1 (en) | 2001-04-19 |
| EP1221847A1 (en) | 2002-07-17 |
| DE60041880D1 (de) | 2009-05-07 |
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